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Huwenbo Shi, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhu Z, Li J, Si J, Ma B, Shi H, Lv J, Cao W, Guo Y, Millwood IY, Walters RG, Lin K, Yang L, Chen Y, Du H, Yu B, Hasegawa K, Camargo CA, Moffatt MF, Cookson WOC, Chen J, Chen Z, Li L, Yu C, Liang L. A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Eur Respir J. 2021 Mar 25. PMID: 33766948.
    Citations:    Fields:    
  2. Shi H, Gazal S, Kanai M, Koch EM, Schoech AP, Siewert KM, Kim SS, Luo Y, Amariuta T, Huang H, Okada Y, Raychaudhuri S, Sunyaev SR, Price AL. Population-specific causal disease effect sizes in functionally important regions impacted by selection. Nat Commun. 2021 02 17; 12(1):1098. PMID: 33597505.
    Citations:    Fields:    Translation:Humans
  3. Lee CH, Shi H, Pasaniuc B, Eskin E, Han B. PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics. Am J Hum Genet. 2021 01 07; 108(1):36-48. PMID: 33352115.
    Citations:    Fields:    Translation:Humans
  4. Shi H, Burch KS, Johnson R, Freund MK, Kichaev G, Mancuso N, Manuel AM, Dong N, Pasaniuc B. Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data. Am J Hum Genet. 2020 06 04; 106(6):805-817. PMID: 32442408.
    Citations: 6     Fields:    Translation:Humans
  5. Zhu Z, Zhu X, Liu CL, Shi H, Shen S, Yang Y, Hasegawa K, Camargo CA, Liang L. Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. Eur Respir J. 2019 12; 54(6). PMID: 31619474.
    Citations: 7     Fields:    Translation:Humans
  6. Julienne H, Shi H, Pasaniuc B, Aschard H. RAISS: robust and accurate imputation from summary statistics. Bioinformatics. 2019 11 01; 35(22):4837-4839. PMID: 31173064.
    Citations: 1     Fields:    
  7. Zhu Z, Guo Y, Shi H, Liu CL, Panganiban RA, Chung W, O'Connor LJ, Himes BE, Gazal S, Hasegawa K, Camargo CA, Qi L, Moffatt MF, Hu FB, Lu Q, Cookson WOC, Liang L. Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank. J Allergy Clin Immunol. 2020 02; 145(2):537-549. PMID: 31669095.
    Citations: 14     Fields:    Translation:HumansAnimals
  8. Hou K, Burch KS, Majumdar A, Shi H, Mancuso N, Wu Y, Sankararaman S, Pasaniuc B. Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture. Nat Genet. 2019 08; 51(8):1244-1251. PMID: 31358995.
    Citations: 8     Fields:    Translation:Humans
  9. Mancuso N, Freund MK, Johnson R, Shi H, Kichaev G, Gusev A, Pasaniuc B. Probabilistic fine-mapping of transcriptome-wide association studies. Nat Genet. 2019 04; 51(4):675-682. PMID: 30926970.
    Citations: 35     Fields:    Translation:HumansCells
  10. Freund MK, Burch KS, Shi H, Mancuso N, Kichaev G, Garske KM, Pan DZ, Miao Z, Mohlke KL, Laakso M, Pajukanta P, Pasaniuc B, Arboleda VA. Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits. Am J Hum Genet. 2018 10 04; 103(4):535-552. PMID: 30290150.
    Citations: 22     Fields:    Translation:HumansCells
  11. Giambartolomei C, Zhenli Liu J, Zhang W, Hauberg M, Shi H, Boocock J, Pickrell J, Jaffe AE, Pasaniuc B, Roussos P. A Bayesian framework for multiple trait colocalization from summary association statistics. Bioinformatics. 2018 08 01; 34(15):2538-2545. PMID: 29579179.
    Citations: 37     Fields:    Translation:HumansCells
  12. Johnson R, Shi H, Pasaniuc B, Sankararaman S. A unifying framework for joint trait analysis under a non-infinitesimal model. Bioinformatics. 2018 07 01; 34(13):i195-i201. PMID: 29949958.
    Citations: 2     Fields:    Translation:Humans
  13. Shi H, Mancuso N, Spendlove S, Pasaniuc B. Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits. Am J Hum Genet. 2017 Nov 02; 101(5):737-751. PMID: 29100087.
    Citations: 33     Fields:    Translation:Humans
  14. Mancuso N, Shi H, Goddard P, Kichaev G, Gusev A, Pasaniuc B. Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits. Am J Hum Genet. 2017 Mar 02; 100(3):473-487. PMID: 28238358.
    Citations: 66     Fields:    Translation:HumansCells
  15. Shi H, Kichaev G, Pasaniuc B. Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data. Am J Hum Genet. 2016 07 07; 99(1):139-53. PMID: 27346688.
    Citations: 85     Fields:    Translation:Humans
  16. Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 07; 7:10979. PMID: 27052111.
    Citations: 22     Fields:    Translation:HumansCells
  17. Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Raitakari OT, Kuusisto J, Laakso M, Price AL, Pajukanta P, Pasaniuc B. Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet. 2016 Mar; 48(3):245-52. PMID: 26854917.
    Citations: 346     Fields:    Translation:HumansAnimalsCells
  18. Shi H, Pasaniuc B, Lange KL. A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data. Bioinformatics. 2015 Nov 01; 31(21):3514-21. PMID: 26139633.
    Citations: 1     Fields:    Translation:HumansCells
  19. Orozco LD, Morselli M, Rubbi L, Guo W, Go J, Shi H, Lopez D, Furlotte NA, Bennett BJ, Farber CR, Ghazalpour A, Zhang MQ, Bahous R, Rozen R, Lusis AJ, Pellegrini M. Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. Cell Metab. 2015 Jun 02; 21(6):905-17. PMID: 26039453.
    Citations: 41     Fields:    Translation:AnimalsCells
  20. Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, Pickrell J, Hirschhorn J, Strachan DP, Patterson N, Price AL. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics. 2014 Oct 15; 30(20):2906-14. PMID: 24990607.
    Citations: 70     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.