Harvard Catalyst Profiles

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Sean Kodani, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kodani SD, Tseng YH. Narrating the story ARC of adipose tissue aging. Dev Cell. 2021 May 17; 56(10):1359-1360. PMID: 34004148.
    Citations:    Fields:    
  2. Morisseau C, Kodani SD, Kamita SG, Yang J, Lee KSS, Hammock BD. Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues. Int J Mol Sci. 2021 May 08; 22(9). PMID: 34066758.
    Citations:    Fields:    
  3. Wilt S, Kodani S, Le TNH, Nguyen L, Vo N, Ly T, Rodriguez M, Hudson PK, Morisseau C, Hammock BD, Pecic S. Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies. Bioorg Chem. 2020 10; 103:104165. PMID: 32891856.
    Citations:    Fields:    Translation:Humans
  4. Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. Front Vet Sci. 2020; 7:580. PMID: 33005645.
  5. Hildreth K, Kodani SD, Hammock BD, Zhao L. Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies. J Nutr Biochem. 2020 12; 86:108484. PMID: 32827665.
    Citations: 5     Fields:    
  6. Rand AA, Rajamani A, Kodani SD, Harris TR, Schlatt L, Barnych B, Passerini AG, Hammock BD. Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2. J Lipid Res. 2019 12; 60(12):1996-2005. PMID: 31641036.
    Citations: 7     Fields:    Translation:HumansCells
  7. Lynes MD, Kodani SD, Tseng YH. Lipokines and Thermogenesis. Endocrinology. 2019 10 01; 160(10):2314-2325. PMID: 31504387.
    Citations: 6     Fields:    Translation:Animals
  8. Lee KSS, Yang J, Niu J, Ng CJ, Wagner KM, Dong H, Kodani SD, Wan D, Morisseau C, Hammock BD. Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. ACS Cent Sci. 2019 Sep 25; 5(9):1614-1624. PMID: 31572788.
    Citations: 8     
  9. Leiria LO, Wang CH, Lynes MD, Yang K, Shamsi F, Sato M, Sugimoto S, Chen EY, Bussberg V, Narain NR, Sansbury BE, Darcy J, Huang TL, Kodani SD, Sakaguchi M, Rocha AL, Schulz TJ, Bartelt A, Hotamisligil GS, Hirshman MF, van Leyen K, Goodyear LJ, Blüher M, Cypess AM, Kiebish MA, Spite M, Tseng YH. 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat. Cell Metab. 2019 10 01; 30(4):768-783.e7. PMID: 31353262.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  10. Hildreth K, Overby H, Kodani S, Morisseau C, Hammock B, Bettaieb A, Zhao L. Soluble Epoxide Hydrolase Inhibitor t-AUCB Promotes Murine Brown Adipogenesis: Role of PPAR Gamma and PPAR Alpha (P21-069-19). Curr Dev Nutr. 2019 Jun; 3(Suppl 1). PMID: 31223951.
  11. Kodani SD, Morisseau C. Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation. Biochimie. 2019 Apr; 159:59-65. PMID: 30716359.
    Citations: 8     Fields:    Translation:HumansCells
  12. Kodani SD, Wan D, Wagner KM, Hwang SH, Morisseau C, Hammock BD. Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. ACS Omega. 2018 Oct 31; 3(10):14076-14086. PMID: 30411058.
    Citations: 5     
  13. Harris TR, Kodani S, Rand AA, Yang J, Imai DM, Hwang SH, Hammock BD. Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol. 2018 08; 94(2):834-841. PMID: 29844231.
    Citations: 6     Fields:    Translation:Animals
  14. Hao L, Kearns J, Scott S, Wu D, Kodani SD, Morisseau C, Hammock BD, Sun X, Zhao L, Wang S. Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther. 2018 06; 365(3):467-475. PMID: 29567865.
    Citations: 3     Fields:    Translation:AnimalsCells
  15. Pecic S, Zeki AA, Xu X, Jin GY, Zhang S, Kodani S, Halim M, Morisseau C, Hammock BD, Deng SX. Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins Other Lipid Mediat. 2018 05; 136:90-95. PMID: 29567338.
    Citations: 5     Fields:    Translation:HumansAnimals
  16. Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD. Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett. 2018 02 15; 28(4):762-768. PMID: 29366648.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  17. Kodani SD, Barthélemy M, Kamita SG, Hammock B, Morisseau C. Development of amide-based fluorescent probes for selective measurement of carboxylesterase 1 activity in tissue extracts. Anal Biochem. 2017 12 15; 539:81-89. PMID: 29054529.
    Citations: 2     Fields:    Translation:HumansCells
  18. Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA. Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension. . 2017 08 01; 313(2):L252-L266. PMID: 28473326.
    Citations: 11     Translation:HumansCells
  19. Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett. 2016 Nov 16; 262:92-99. PMID: 27659731.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  20. Harris TR, Kodani S, Yang J, Imai DM, Hammock BD. An ?-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis. J Nutr Biochem. 2016 12; 38:93-101. PMID: 27732914.
    Citations: 3     Fields:    Translation:AnimalsCells
  21. Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang GY, Inceoglu B, Hammock BD. Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers. J Pharmacol Exp Ther. 2016 06; 357(3):529-36. PMID: 26989141.
    Citations: 23     Fields:    Translation:Animals
  22. Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, da Silva CA, Morisseau C, Hammock BD. Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE2 induced pain model. Toxicol Appl Pharmacol. 2015 Dec 15; 289(3):419-27. PMID: 26522832.
    Citations: 9     Fields:    Translation:AnimalsCells
  23. Harris TR, Bettaieb A, Kodani S, Dong H, Myers R, Chiamvimonvat N, Haj FG, Hammock BD. Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice. Toxicol Appl Pharmacol. 2015 Jul 15; 286(2):102-11. PMID: 25827057.
    Citations: 33     Fields:    Translation:Animals
  24. Kodani SD, Hammock BD. The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain. Drug Metab Dispos. 2015 May; 43(5):788-802. PMID: 25762541.
    Citations: 28     Fields:    Translation:HumansAnimals
  25. Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD. Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. J Lipid Res. 2014 06; 55(6):1131-8. PMID: 24771868.
    Citations: 20     Fields:    Translation:HumansCells
  26. Zhang G, Kodani S, Hammock BD. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer. Prog Lipid Res. 2014 Jan; 53:108-23. PMID: 24345640.
    Citations: 58     Fields:    Translation:HumansAnimals
  27. Chan JK, Charrier JG, Kodani SD, Vogel CF, Kado SY, Anderson DS, Anastasio C, Van Winkle LS. Combustion-derived flame generated ultrafine soot generates reactive oxygen species and activates Nrf2 antioxidants differently in neonatal and adult rat lungs. Part Fibre Toxicol. 2013 Aug 01; 10:34. PMID: 23902943.
    Citations: 21     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  28. Chan JK, Vogel CF, Baek J, Kodani SD, Uppal RS, Bein KJ, Anderson DS, Van Winkle LS. Combustion derived ultrafine particles induce cytochrome P-450 expression in specific lung compartments in the developing neonatal and adult rat. . 2013 May 15; 304(10):L665-77. PMID: 23502512.
    Citations: 8     Translation:HumansAnimalsCells
  29. Liyasova MS, Schopfer LM, Kodani S, Lantz SR, Casida JE, Lockridge O. Newly observed spontaneous activation of ethephon as a butyrylcholinesterase inhibitor. Chem Res Toxicol. 2013 Mar 18; 26(3):422-31. PMID: 23410221.
    Citations: 1     Fields:    Translation:HumansCells
  30. Chan JK, Kodani SD, Charrier JG, Morin D, Edwards PC, Anderson DS, Anastasio C, Van Winkle LS. Age-specific effects on rat lung glutathione and antioxidant enzymes after inhaling ultrafine soot. Am J Respir Cell Mol Biol. 2013 Jan; 48(1):114-24. PMID: 23065132.
    Citations: 9     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.