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Konstantinos Kokkaliaris, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kfoury YS, Ji F, Mazzola M, Sykes DB, Scherer AK, Anselmo A, Akiyama Y, Mercier F, Severe N, Kokkaliaris KD, Zhao T, Brouse T, Saez B, Seidl J, Papazian A, Ivanov P, Mansour MK, Sadreyev RI, Scadden DT. tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche. Cell Stem Cell. 2021 Sep 15. PMID: 34551362.
    Citations:    Fields:    
  2. Kokkaliaris KD, Kunz L, Cabezas-Wallscheid N, Christodoulou C, Renders S, Camargo F, Trumpp A, Scadden DT, Schroeder T. Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations. Blood. 2020 11 12; 136(20):2296-2307. PMID: 32766876.
    Citations: 12     Fields:    Translation:AnimalsCells
  3. Kokkaliaris KD, Scadden DT. Cell interactions in the bone marrow microenvironment affecting myeloid malignancies. Blood Adv. 2020 08 11; 4(15):3795-3803. PMID: 32780848.
    Citations: 9     Fields:    Translation:HumansCells
  4. Stadler T, Skylaki S, Kokkaliaris KD, Schroeder T. Erratum to "On the statistical analysis of single cell lineage trees" [J. Theor. Biol. 439 (2018) 160-165]. J Theor Biol. 2020 12 07; 506:110424. PMID: 32741579.
    Citations:    Fields:    
  5. Kokkaliaris KD. Dissecting the spatial bone marrow microenvironment of hematopoietic stem cells. Curr Opin Oncol. 2020 03; 32(2):154-161. PMID: 32022758.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  6. Christodoulou C, Spencer JA, Yeh SA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Guo G, Seyedhassantehrani N, Esipova TV, Vinogradov SA, Rudzinskas S, Zhang Y, Perkins AS, Orkin SH, Calogero RA, Schroeder T, Lin CP, Camargo FD. Live-animal imaging of native haematopoietic stem and progenitor cells. Nature. 2020 02; 578(7794):278-283. PMID: 32025033.
    Citations: 44     Fields:    Translation:AnimalsCells
  7. Loeffler D, Wehling A, Schneiter F, Zhang Y, Müller-Bötticher N, Hoppe PS, Hilsenbeck O, Kokkaliaris KD, Endele M, Schroeder T. Asymmetric lysosome inheritance predicts activation of haematopoietic stem cells. Nature. 2019 09; 573(7774):426-429. PMID: 31485073.
    Citations: 29     Fields:    
  8. Loeffler D, Wehling A, Schneiter F, Zhang Y, Müller-Bötticher N, Hoppe PS, Hilsenbeck O, Kokkaliaris KD, Endele M, Schroeder T. Publisher Correction: Asymmetric lysosome inheritance predicts activation of haematopoietic stem cells. Nature. 2019 Sep; 573(7775):E5. PMID: 31515536.
    Citations:    Fields:    
  9. Bourgine PE, Fritsch K, Pigeot S, Takizawa H, Kunz L, Kokkaliaris KD, Coutu DL, Manz MG, Martin I, Schroeder T. Fate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organs. iScience. 2019 Sep 27; 19:504-513. PMID: 31442666.
    Citations: 5     
  10. Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT. Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019 Oct 03; 25(4):570-583.e7. PMID: 31279774.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  11. Baryawno N, Przybylski D, Kowalczyk MS, Kfoury Y, Severe N, Gustafsson K, Kokkaliaris KD, Mercier F, Tabaka M, Hofree M, Dionne D, Papazian A, Lee D, Ashenberg O, Subramanian A, Vaishnav ED, Rozenblatt-Rosen O, Regev A, Scadden DT. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia. Cell. 2019 06 13; 177(7):1915-1932.e16. PMID: 31130381.
    Citations: 153     Fields:    Translation:HumansAnimalsCells
  12. Etzrodt M, Ahmed N, Hoppe PS, Loeffler D, Skylaki S, Hilsenbeck O, Kokkaliaris KD, Kaltenbach HM, Stelling J, Nerlov C, Schroeder T. Inflammatory signals directly instruct PU.1 in HSCs via TNF. Blood. 2019 02 21; 133(8):816-819. PMID: 30301719.
    Citations: 21     Fields:    Translation:AnimalsCells
  13. Dettinger P, Frank T, Etzrodt M, Ahmed N, Reimann A, Trenzinger C, Loeffler D, Kokkaliaris KD, Schroeder T, Tay S. Automated Microfluidic System for Dynamic Stimulation and Tracking of Single Cells. Anal Chem. 2018 09 18; 90(18):10695-10700. PMID: 30059208.
    Citations: 6     Fields:    Translation:AnimalsCells
  14. Strasser MK, Hoppe PS, Loeffler D, Kokkaliaris KD, Schroeder T, Theis FJ, Marr C. Lineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm. Nat Commun. 2018 07 12; 9(1):2697. PMID: 30002371.
    Citations: 7     Fields:    Translation:AnimalsCells
  15. Bourgine PE, Klein T, Paczulla AM, Shimizu T, Kunz L, Kokkaliaris KD, Coutu DL, Lengerke C, Skoda R, Schroeder T, Martin I. In vitro biomimetic engineering of a human hematopoietic niche with functional properties. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):E5688-E5695. PMID: 29866839.
    Citations: 28     Fields:    Translation:HumansCells
  16. Hastreiter S, Skylaki S, Loeffler D, Reimann A, Hilsenbeck O, Hoppe PS, Coutu DL, Kokkaliaris KD, Schwarzfischer M, Anastassiadis K, Theis FJ, Schroeder T. Inductive and Selective Effects of GSK3 and MEK Inhibition on Nanog Heterogeneity in Embryonic Stem Cells. Stem Cell Reports. 2018 07 10; 11(1):58-69. PMID: 29779897.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T. Three-dimensional map of nonhematopoietic bone and bone-marrow cells and molecules. Nat Biotechnol. 2017 Dec; 35(12):1202-1210. PMID: 29131149.
    Citations: 37     Fields:    Translation:AnimalsCells
  18. Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T. Multicolor quantitative confocal imaging cytometry. Nat Methods. 2018 01; 15(1):39-46. PMID: 29320487.
    Citations: 26     Fields:    Translation:Animals
  19. Buggenthin F, Buettner F, Hoppe PS, Endele M, Kroiss M, Strasser M, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Schroeder T, Theis FJ, Marr C. Prospective identification of hematopoietic lineage choice by deep learning. Nat Methods. 2017 Apr; 14(4):403-406. PMID: 28218899.
    Citations: 31     Fields:    Translation:AnimalsCells
  20. Endele M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Skylaki S, Hoppe PS, Schambach A, Stanley ER, Schroeder T. CSF-1-induced Src signaling can instruct monocytic lineage choice. Blood. 2017 03 23; 129(12):1691-1701. PMID: 28159742.
    Citations: 5     Fields:    Translation:AnimalsCells
  21. Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA, Marr C, Strasser MK, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H, Nerlov C, Theis FJ, Schroeder T. Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature. 2016 07 14; 535(7611):299-302. PMID: 27411635.
    Citations: 70     Fields:    Translation:AnimalsCells
  22. Hilsenbeck O, Schwarzfischer M, Skylaki S, Schauberger B, Hoppe PS, Loeffler D, Kokkaliaris KD, Hastreiter S, Skylaki E, Filipczyk A, Strasser M, Buggenthin F, Feigelman JS, Krumsiek J, van den Berg AJ, Endele M, Etzrodt M, Marr C, Theis FJ, Schroeder T. Software tools for single-cell tracking and quantification of cellular and molecular properties. Nat Biotechnol. 2016 07 12; 34(7):703-6. PMID: 27404877.
    Citations: 42     Fields:    
  23. Kokkaliaris KD, Drew E, Endele M, Loeffler D, Hoppe PS, Hilsenbeck O, Schauberger B, Hinzen C, Skylaki S, Theodorou M, Kieslinger M, Lemischka I, Moore K, Schroeder T. Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification. Blood. 2016 09 01; 128(9):1181-92. PMID: 27365423.
    Citations: 10     Fields:    Translation:AnimalsCells
  24. Kokkaliaris KD, Lucas D, Beerman I, Kent DG, Perié L. Understanding hematopoiesis from a single-cell standpoint. Exp Hematol. 2016 06; 44(6):447-50. PMID: 26997547.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  25. Sykes SM, Kokkaliaris KD, Milsom MD, Levine RL, Majeti R. Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia. Exp Hematol. 2015 Dec; 43(12):989-92. PMID: 26455528.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  26. Yilmaz A, Engeler R, Constantinescu S, Kokkaliaris KD, Dimitrakopoulos C, Schroeder T, Beerenwinkel N, Paro R. Ectopic expression of Msx2 in mammalian myotubes recapitulates aspects of amphibian muscle dedifferentiation. Stem Cell Res. 2015 Nov; 15(3):542-553. PMID: 26468601.
    Citations: 4     Fields:    Translation:AnimalsCells
  27. Filipczyk A, Marr C, Hastreiter S, Feigelman J, Schwarzfischer M, Hoppe PS, Loeffler D, Kokkaliaris KD, Endele M, Schauberger B, Hilsenbeck O, Skylaki S, Hasenauer J, Anastassiadis K, Theis FJ, Schroeder T. Network plasticity of pluripotency transcription factors in embryonic stem cells. Nat Cell Biol. 2015 Oct; 17(10):1235-46. PMID: 26389663.
    Citations: 50     Fields:    Translation:AnimalsCells
  28. Mende N, Kuchen EE, Lesche M, Grinenko T, Kokkaliaris KD, Hanenberg H, Lindemann D, Dahl A, Platz A, Höfer T, Calegari F, Waskow C. CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo. J Exp Med. 2015 Jul 27; 212(8):1171-83. PMID: 26150472.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  29. Trompouki E, King KY, Will B, Lessard J, Flores-Figueroa E, Kokkaliaris KD, Bowman T. Bloody signals: from birth to disease and death. Exp Hematol. 2014 Dec; 42(12):989-94. PMID: 25482344.
    Citations:    Fields:    Translation:HumansAnimalsCells
  30. Margaritis LH, Manta AK, Kokkaliaris KD, Schiza D, Alimisis K, Barkas G, Georgiou E, Giannakopoulou O, Kollia I, Kontogianni G, Kourouzidou A, Myari A, Roumelioti F, Skouroliakou A, Sykioti V, Varda G, Xenos K, Ziomas K. Drosophila oogenesis as a bio-marker responding to EMF sources. Electromagn Biol Med. 2014 Sep; 33(3):165-89. PMID: 23915130.
    Citations: 5     Fields:    Translation:AnimalsPHPublic Health
  31. Montrone C, Kokkaliaris KD, Loeffler D, Lechner M, Kastenmüller G, Schroeder T, Ruepp A. HSC-explorer: a curated database for hematopoietic stem cells. PLoS One. 2013; 8(7):e70348. PMID: 23936191.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  32. Swiers G, Baumann C, O'Rourke J, Giannoulatou E, Taylor S, Joshi A, Moignard V, Pina C, Bee T, Kokkaliaris KD, Yoshimoto M, Yoder MC, Frampton J, Schroeder T, Enver T, Göttgens B, de Bruijn MFTR. Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level. Nat Commun. 2013; 4:2924. PMID: 24326267.
    Citations: 75     Fields:    Translation:AnimalsCells
  33. Kokkaliaris KD, Loeffler D, Schroeder T. Advances in tracking hematopoiesis at the single-cell level. Curr Opin Hematol. 2012 Jul; 19(4):243-9. PMID: 22555393.
    Citations: 7     Fields:    Translation:HumansCells
  34. Jackson M, Axton RA, Taylor AH, Wilson JA, Gordon-Keylock SA, Kokkaliaris KD, Brickman JM, Schulz H, Hummel O, Hubner N, Forrester LM. HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche. Stem Cells. 2012 Feb; 30(2):150-60. PMID: 22084016.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  35. Loeffler D, Kokkaliaris KD, Schroeder T. Wnt to notch relay signaling induces definitive hematopoiesis. Cell Stem Cell. 2011 Jul 08; 9(1):2-4. PMID: 21726826.
    Citations: 4     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.