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Kevin Arturo Pacheco Barrios, M.D.

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San Martin de Porres University, PeruMD05/2016Medicine
Cayetano Heredia University, PeruMSc03/2019Neuroscience
Spaulding Rehabilitation Hospital & Massachusetts General Hospital, Harvard Medical School, USACurrentNeuromodulation


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AT009491 (FREGNI, FELIPE) Aug 6, 2018 - Jul 31, 2023
    Optimized tDCS for fibromyalgia: targeting the endogenous pain control system
    Role: Co-Investigator
  2. R01HD082302 (FREGNI, FELIPE) Aug 1, 2015 - Apr 30, 2020
    Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and tDCS
    Role: Co-Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fregni F, El-Hagrassy MM, Pacheco-Barrios K, Carvalho S, Leite J, Simis M, Brunelin J, Nakamura-Palacios EM, Marangolo P, Venkatasubramanian G, San-Juan D, Caumo W, Bikson M, Brunoni AR. Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders. Int J Neuropsychopharmacol. 2021 Apr 21; 24(4):256-313. PMID: 32710772.
    Citations: 9     Fields:    
  2. Kevin Pacheco-Barrios, Damaris Ramirez-Alva, Ana Balbuena-Pareja, Niels Pacheco-Barrios, Stefano Giannoni-Luza, Anna Carolina Gianlorenco, Luna Vasconcelos Felippe, Ivan Chacha-Angulo, Felipe Fregni. Annals of Neurology. Worldwide Frequency of Phantom Limb Pain in People with Amputations: A Systematic Review and Meta-Analysis. 2020; 88:S244-S245. View Publication.
  3. Isabel Pinedo-Torres, Magaly Flores-Fernández, Marlon Yovera-Aldana, Claudia Gutierrez-Ortiz, Paolo Zegarra-Lizana, Claudio Intimayta-Escalante, Cristian Moran-Mariños, Carlos Alva-Diaz, Kevin Pacheco-Barrios. Prevalence of Diabetes Mellitus and Its Associated Unfavorable Outcomes in Patients With Acute Respiratory Syndromes Due to Coronaviruses Infection: A Systematic Review and Meta-Analysis. Clinical Medicine Insights: Endocrinology and Diabetes. 2020. View Publication.
  4. Carlos Alva-Diaz, Christoper A Alarcon-Ruiz, Kevin Pacheco-Barrios, Nicanor Mori, Josmel Pacheco-Mendoza, Bryan J Traynor, Andrea Rivera-Valdivia, Pongtawat Lertwilaiwittaya, Thomas D Bird, Mario Cornejo-Olivas. C9orf72 hexanucleotide repeat in Huntington-like patients: Systematic review and meta-analysis. Frontiers in Genetics. 2020. View Publication.
  5. Jose Ernesto Fernandez-Chinguel, Niels Pacheco-Barrios, Martina Guillermo-Roman, Aaron Rodriguez Calienes, Kevin Pacheco-Barrios. Annals of Neurology. Global Prevalence of Tuberculosis in the Central Nervous System: A Systematic Review and Meta-Analysis. 2020; 88:S141-S142. View Publication.
  6. Alba Navarro-Flores, Oscar Rivera-Torrejon, Andrely Huerta-Rosario, Roberto A Molina, Victor Velasquez-Rimachi, Carlos Alva-Diaz, Kevin Pacheco-Barrios. Annals of Neurology. Prevalence of Epilepsy in Latin America and the Caribbean (LAC): A Systematic Review and Meta-Analysis. 2020; 88:S137-S137. View Publication.
  7. Zeng H, Pacheco-Barrios K, Cao Y, Li Y, Zhang J, Yang C, Fregni F. Non-invasive neuromodulation effects on painful diabetic peripheral neuropathy: a systematic review and meta-analysis. Sci Rep. 2020 11 05; 10(1):19184. PMID: 33154432.
    Citations:    Fields:    Translation:Humans
  8. Pacheco-Barrios K, Meng X, Fregni F. Neuromodulation Techniques in Phantom Limb Pain: A Systematic Review and Meta-analysis. Pain Med. 2020 10 01; 21(10):2310-2322. PMID: 32176286.
    Citations: 1     Fields:    Translation:Humans
  9. Pacheco-Barrios, K., Gianlorenço, A. C., Machado, R., Queiroga, M., Zeng, H., Shaikh, E., Yang, Y., Nogueira, B., Castelo-Branco, L., & Fregni, F. Exercise-induced pain threshold modulation in healthy subjects: a systematic review and meta-analysis. Principles and Practice of Clinical Research. 2020; 3(6):18-24. View Publication.
  10. Andrely Huerta-Rosario, Roberto A Molina, Jésica J Ventura-Chilón, Aníbal Terreros, Carlos Alva-Diaz, Kevin Pacheco-Barrios, Roberto Romero Sánchez, Nicanor Mori Quispe. Chronic meningitis as an initial presentation of Sjögren syndrome. Revista Colombiana de Reumatología (Spanish). 2020; 3(28). View Publication.
  11. Kevin Pacheco-Barrios, Huiyan Zeng, Ying Cao, Ying Li, Jimming Zhang, Caifeng Yang, Felipe Fregni. Neurology. Non-Invasive Neuromodulation in Diabetic Peripheral Neuropathy: a meta-analysis (5484). 2020; 94(15 Supplem). View Publication.
  12. Kevin Pacheco-Barrios, Stefano Gianonni-Luza, Ana Balbuena, Carlos Alva-Diaz. Neurology. Burden of disease due to stroke and risk factors in Latin America: an analysis of the Global Burden Disease Study (5444). 2020; 94(15 Supplem). View Publication.
  13. Pacheco-Barrios K, Cardenas-Rojas A, Giannoni-Luza S, Fregni F. COVID-19 pandemic and Farr's law: A global comparison and prediction of outbreak acceleration and deceleration rates. PLoS One. 2020; 15(9):e0239175. PMID: 32941485.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  14. Pacheco-Barrios K, Cardenas-Rojas A, Thibaut A, Costa B, Ferreira I, Caumo W, Fregni F. Methods and strategies of tDCS for the treatment of pain: current status and future directions. Expert Rev Med Devices. 2020 Sep; 17(9):879-898. PMID: 32845195.
    Citations:    Fields:    Translation:Humans
  15. Giannoni-Luza S, Pacheco-Barrios K, Cardenas-Rojas A, Mejia-Pando PF, Luna-Cuadros MA, Barouh JL, Gnoatto-Medeiros M, Candido-Santos L, Barra A, Caumo W, Fregni F. Noninvasive motor cortex stimulation effects on quantitative sensory testing in healthy and chronic pain subjects: a systematic review and meta-analysis. Pain. 2020 09 01; 161(9):1955-1975. PMID: 32453135.
    Citations:    Fields:    Translation:Humans
  16. Carlos Alva-Díaz, Victor Velásquez-Rimachi, Cristian Morán-Mariños, Mariela Osores-Flores, Jorge Chachaima-Mar, Andrely Huerta-Rosario, Roberto A Molina, Oscar Rivera-Torrejón, Isabel Pinedo-Torres, Boris Verona-Mesia, Mariela Huerta-Rosario, Kevin Pacheco-Barrios, Tatiana Metcalf. Treatment guidelines for COVID-19 infected patients. Med Int Méx (Spanish). 2020; 4(36):509-529. View Publication.
  17. Duarte D, Bauer CCC, Pinto CB, Saleh Velez FG, Estudillo-Guerra MA, Pacheco-Barrios K, Gunduz ME, Crandell D, Merabet L, Fregni F. Cortical plasticity in phantom limb pain: A fMRI study on the neural correlates of behavioral clinical manifestations. Psychiatry Res Neuroimaging. 2020 10 30; 304:111151. PMID: 32738724.
    Citations: 1     Fields:    Translation:Humans
  18. AJ. Mendes, K. Pacheco-Barrios, P.Gonzalez-Mego, A.Sanchez, F.Fregni. Ten strategies to formulate a strong research question. Principles and Practice of Clinical Research Journal. 2020; 2(6):21-24. View Publication.
  19. Pacheco-Barrios K, Pinto CB, Saleh Velez FG, Duarte D, Gunduz ME, Simis M, Lepesteur Gianlorenco AC, Barouh JL, Crandell D, Guidetti M, Battistella L, Fregni F. Structural and functional motor cortex asymmetry in unilateral lower limb amputation with phantom limb pain. Clin Neurophysiol. 2020 10; 131(10):2375-2382. PMID: 32828040.
    Citations: 1     Fields:    Translation:Humans
  20. Uygur-Kucukseymen E, Castelo-Branco L, Pacheco-Barrios K, Luna-Cuadros MA, Cardenas-Rojas A, Giannoni-Luza S, Zeng H, Gianlorenco AC, Gnoatto-Medeiros M, Shaikh ES, Caumo W, Fregni F. Decreased neural inhibitory state in fibromyalgia pain: A cross-sectional study. Neurophysiol Clin. 2020 Sep; 50(4):279-288. PMID: 32654884.
    Citations:    Fields:    
  21. Navarro-Flores A, Alva-Diaz C, Pacheco-Barrios K, Vasquez-Quicaño K, Quispe NM, Sanchez RR. Adult-Onset Rasmussen’s Encephalitis: Response After Steroid Pulses. Sinapse. 2020; 20(1). View Publication.
  22. Alva-Diaz C; Huerta-Rosario A; Molina RA; Pacheco-Barrios K; Aguirre-Quispe W; Navarro-Flores A; Velásquez-Rimachi V; Sinche-Espinal HA; Ocampo-Zegarra JC; Andamayo-Villalba LA; Metcalf T; Chahua M; Romero Sanchez R. Mental and substance use disorders in Peru: a systematic analysis of the Global Burden of Disease study. Zeitschrift fur Gesundheitswissenschaften. 2020. View Publication.
  23. Alva-Díaz C, Huerta-Rosario A, Pacheco-Barrios K, Molina RA, Navarro-Flores A, Aguirre-Quispe W, Custodio N, Toro-Perez J, Mori N, Romero-Sanchez R. Neurological diseases in Peru: a systematic analysis of the global burden disease study. Arq Neuropsiquiatr. 2020 05; 78(5):282-289. PMID: 32490965.
    Citations:    Fields:    Translation:Humans
  24. Velásquez-Rimachi V, Orellana-Tovar I, Rodriguez-López E, López-Saavedra A, Esteban-Arias D, Pacheco-Barrios K, Metcalf T, Alva-Diaz C. Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review. Indian J Tuberc. 2020 Jul; 67(3):286-294. PMID: 32825855.
    Citations:    Fields:    
  25. Simis M, Uygur-Kucukseymen E, Pacheco-Barrios K, Battistella LR, Fregni F. Beta-band oscillations as a biomarker of gait recovery in spinal cord injury patients: A quantitative electroencephalography analysis. Clin Neurophysiol. 2020 08; 131(8):1806-1814. PMID: 32540720.
    Citations: 1     Fields:    Translation:Humans
  26. Pacheco-Barrios K, Fregni F. Evidence-based decision making during COVID-19 pandemic. Princ Pract Clin Res. 2020 Jan-Apr; 6(1):1-2. PMID: 32766450.
  27. Estudillo-Guerra MA, Pacheco-Barrios K, Cardenas-Rojas A, Adame-Ocampo G, Camprodon JA, Morales-Quezada L, Gutiérrez-Mora D, Flores-Ramos M. Brain perfusion during manic episode and at 6-month follow-up period in bipolar disorder patients: Correlation with cognitive functions. Brain Behav. 2020 06; 10(6):e01615. PMID: 32356600.
    Citations: 1     Fields:    
  28. Gunduz ME, Pinto CB, Saleh Velez FG, Duarte D, Pacheco-Barrios K, Lopes F, Fregni F. Motor Cortex Reorganization in Limb Amputation: A Systematic Review of TMS Motor Mapping Studies. Front Neurosci. 2020; 14:314. PMID: 32372907.
    Citations: 3     
  29. Münger M, Pinto CB, Pacheco-Barrios K, Duarte D, Enes Gunduz M, Simis M, Battistella LR, Fregni F. Protective and Risk Factors for Phantom Limb Pain and Residual Limb Pain Severity. Pain Pract. 2020 07; 20(6):578-587. PMID: 32176435.
    Citations: 1     Fields:    Translation:Humans
  30. Joel Mario Sequeiros-Chirinos; Carlos A. Alva-Díaz; Kevin Pacheco-Barrios; Jorge Huaringa-Marcelo; Charles Huamaní; Carla E. Camarena-Flores; Walter S. Durand-Castro; Ana María Valencia-Chávez; Rosa L. Ecos-Quispe; Paula I. Estupinan-Valdez; Marla Gallo-Guerrero; Marlene Doris Huamaní-Mendoza; Evelyn Vanessa Mariños-Sánchez; María Elizabeth Morón-Cabrera; Elena Pulachet-Contreras; Alfredo Ramos-Auccasi; Liliana Rodríguez-Kadota; César Saavedra-Rocha; Lesly Chávez-Rimache; Raúl Timaná Ruíz. Diagnosis and therapy for the acute stage of ischemic cerebrovascular accident: A clinical practice guideline from Peruvian Social Security (EsSalud). Acta Médica Peruana (Spanish). 2020. View Publication.
  31. Cardenas-Rojas A, Pacheco-Barrios K, Giannoni-Luza S, Rivera-Torrejon O, Fregni F. Noninvasive brain stimulation combined with exercise in chronic pain: a systematic review and meta-analysis. Expert Rev Neurother. 2020 04; 20(4):401-412. PMID: 32130037.
    Citations: 2     Fields:    Translation:Humans
  32. Javier Héctor Cáceres-del-Carpio; Renzo Cañote Flores; José Montes-Alvis; Kevin Pacheco-Barrios; Doris Quiroz-Cerna; Vanesa Cinthia Luján-Donayre; Guillermo Reátegui-Escalante; Robinson Richard Escobedo-Arriola; Pedro Manuel García-Rodríguez; Enrique Chacón-Rosello; J. Yolanda Chahua- Torres; Harvy Alberto Honorio-Morales; Antonio Martín Touzett-Valera; Héctor Eduardo Shimabuku- Ysa; Lesly Chávez-Rimache; Alvaro Taype-Rondan; Raúl Timaná-Ruiz. Diagnosis and treatment of diabetic retinopathy and diabetic macular edema: clinical practice guidelines of the Peruvian Health Social Security (EsSalud). Anales de la Facultad de Medicina (Spanish). 2020. View Publication.
  33. Ballester M, Orrego C, Heijmans M, Alonso-Coello P, Versteegh MM, Mavridis D, Groene O, Immonen K, Wagner C, Canelo-Aybar C, Sunol R. Comparing the effectiveness and cost-effectiveness of self-management interventions in four high-priority chronic conditions in Europe (COMPAR-EU): a research protocol. BMJ Open. 2020 01 19; 10(1):e034680. PMID: 31959612.
    Citations: 3     Fields:    Translation:Humans
  34. Carlos Alva-Diaz; Nicanor Mori; Kevin Pacheco-Barrios; Victor Velásquez-Rimachi; Oscar Rivera-Torrejon; Cristina Andrely Huerta-Rosario; Christoper A. Alarcon-Ruiz; María Meza-Vega; Yrma Quispe-Zapana; Isabel Tagle-Lostaunau; Juan Luis Cam-Paucar; Francisco Aquino-Peña; Víctor Vargas-Bellina; Gladys Guillen-Tello; Víctor Campuzano-Lezama; Gloria Amalia Vargas-Nuñez; Leonel Mario Lozano-Vasquez; Pilar Elena Mazzetti-Soler. Clinical practice guideline for the diagnosis and treatment of Guillain-Barre syndrome. Neurología Argentina (Spanish). 2020; 12(1):36-48. View Publication.
  35. Zafra-Tanaka JH, Pacheco-Barrios K, Inga-Berrospi F, Taype-Rondan A. Self-perceived competencies in the diagnosis and treatment of mental health disorders among general practitioners in Lima, Peru. BMC Med Educ. 2019 Dec 16; 19(1):464. PMID: 31842855.
    Citations: 1     Fields:    Translation:Humans
  36. Castelo-Branco L, Uygur Kucukseymen E, Duarte D, El-Hagrassy MM, Bonin Pinto C, Gunduz ME, Cardenas-Rojas A, Pacheco-Barrios K, Yang Y, Gonzalez-Mego P, Estudillo-Guerra A, Candido-Santos L, Mesia-Toledo I, Rafferty H, Caumo W, Fregni F. Optimised transcranial direct current stimulation (tDCS) for fibromyalgia-targeting the endogenous pain control system: a randomised, double-blind, factorial clinical trial protocol. BMJ Open. 2019 10 30; 9(10):e032710. PMID: 31672712.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  37. Pacheco-Barrios, K.; Giannoni-Luza, S.; Alva-Diaz, C. Burden of disease due to stroke in Latin America: A systematic analysis of the global burden disease study 2017. Journal of the Neurological Sciences. 2019. View Publication.
  38. Pacheco-Barrios, K.; Cardenas-Rojas, A.; Alva-Diaz, C. Burden of disease due to epilepsy in Latin America: A systematic analysis of the global burden disease study 2017. Journal of the Neurological Sciences. 2019. View Publication.
  39. José E. Chavez; Jessica H. Zafra-Tanaka; Kevin Pacheco-Barrios; José Montes-Alvis; Alvaro Taype-Rondan; Víctor M. Gallegos; Juana Arias; Jorge M. Cucho; Daniel Roberto Flores; Mónica Parra-Otárola; Luz A. Pecho; María Lazo-Porras; Raúl Timaná. Clinical practice guidelines for the diagnosis and management of osteoarthritis in Peruvian Social Security (EsSalud). Acta Médica Peruana (Spanish). 2019. View Publication.
  40. Villegas, Bruno; Flores, Kevin M.; Pacheco-Barrios, Kevin; Elias, Dante. Monitoring of respiratory patterns and biosignals during speech from adults who stutter and do not stutter: A comparative analysis. 13th International Symposium on Medical Information and Communication Technology (ISMICT). 2019. View Publication.
  41. Velásquez-Rimachi V, Palma-García L, Pacheco-Barrios K, Alva-Díaz C. Successful treatment of catastrophic antiphospholipid syndrome with therapeutic plasma exchange: a case report. Hematol Transfus Cell Ther. 2020 Jul - Sep; 42(3):287-291. PMID: 31537477.
  42. Bustamante-Chavez, Hugo; Pacheco-Barrios, Niels; Alva-Diaz, Carlos; Pacheco-Barrios, Kevin. Efficacy of Prednisolone in the Treatment of Infantile Spasms: Systematic Review and Meta-Analysis. Annals of Neurology. 2019.
  43. Pacheco-Barrios, K.; Alva-Diaz, C.; Velasquez-Rimachi, V.; Moran-Marinos, C.; Chilon, J. Ventura; Huerta-Rosario, A.; Molina, R.; Farronay, C. . Epidemiology of Headache in Latin America: A Systematic Review and Meta-analysis of Its Prevalence and Incidence. Headache. 2019.
  44. Villegas B, Flores KM, Jose Acuna K, Pacheco-Barrios K, Elias D. A Novel Stuttering Disfluency Classification System Based on Respiratory Biosignals. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:4660-4663. PMID: 31946902.
    Citations:    Translation:Humans
  45. Richard Soto-Becerra; Jessica Hanae Zafra-Tanaka; Sergio Goicochea-Lugo; Christoper A. Alarcón-Ruiz; Kevin Pacheco-Barrios; Alvaro Taype-Rondan; Carolina Guevara-Caicedo; Gladys Espinoza-Rivas; Mario Cabrera-Saldaña; Pío Zelaya-Castro; Ricardo Zegarra-Carhuaz; Diana Urday-Ipanaqué; Raúl Timaná-Ruiz. Clinical practice guideline for the management of atrial fibrillation for the Peruvian Social Security (EsSalud). Anales de la Facultad de Medicina. 2019. View Publication.
  46. Zafra-Tanaka JH, Pacheco-Barrios K, Tellez WA, Taype-Rondan A. Effects of dog-assisted therapy in adults with dementia: a systematic review and meta-analysis. BMC Psychiatry. 2019 01 24; 19(1):41. PMID: 30678665.
    Citations: 12     Fields:    Translation:HumansAnimals
  47. Achanccaray, D., Pacheco, K., Carranza, E., Hayashibe, M. Immersive Virtual Reality Feedback in a Brain Computer Interface for Upper Limb Rehabilitation. 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. 2019; 1006-1010. View Publication.
  48. Pacheco Barrios, K., Alva-Diaz, C., Huerta-Rosario, A., Navarro-Flores, A., Molina-Nino de Guzman, R., & Mori, N. Burden of Neurological Diseases in Peru 1990-2015: A Systematic Analysis of the Global Burden Disease 2015. Annals of Neurology. 2018; 84:S81-S82.. View Publication.
  49. Pacheco-Barrios, K., Carranza-Urquizo, E., Acchancaray, D. A., & Aguilar Mendoza, L. Immersive Virtual Reality Feedback in a Brain Computer Interface for Upper Limb Rehabilitation: A Pilot Study. Annals of Neurology. 2018; 84:S60-S60.. View Publication.
  50. Pacheco-Barrios, K., Pacheco-Barrios, N., Alva-Diaz, C., & Velasquez, V. Efficacy of the Use of Dihydroergotamine in the Management of Migraine Attacks: A Systematic Review with Meta-Analysis. Annals of Neurology. 2018; 84:S185-S185 . View Publication.
  51. Pérez-Lazo G, Maquera-Afaray J, Soca R, Pacheco-Barrios K, Castillo-Córdova R. Fungal biofilm associated with long-term central venous access device: Complications and therapeutic difficulties. Horizonte Medico (Spanish). 2018; 18(2):86-91. View Publication.
  52. Timpel P, Cesena FHY, da Silva Costa C, Soldatelli MD, Gois E, Castrillon E, Díaz LJJ, Repetto GM, Hagos F, Castillo Yermenos RE, Pacheco-Barrios K, Musallam W, Braid Z, Khidir N, Romo Guardado M, Roepke RML. Efficacy of gamification-based smartphone application for weight loss in overweight and obese adolescents: study protocol for a phase II randomized controlled trial. Ther Adv Endocrinol Metab. 2018 Jun; 9(6):167-176. PMID: 29854386.
    Citations: 2     
  53. Pacheco K, Acuna K, Carranza E, Achanccaray D, Andreu-Perez J. Performance predictors of motor imagery brain-computer interface based on spatial abilities for upper limb rehabilitation. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:1014-1017. PMID: 29060046.
    Citations: 2     Translation:Humans
  54. Montes J., Pacheco K, Figueroa J, Inga V, Ortega Y, Flores C, Acosta E, Torres V, Salazar A. Analysis of the acute anti-inflammatory and analgesic activity of metformin by the Formalin Test. Horizonte Médico (Spanish). 2012; 12(2):37-42. View Publication.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.