Harvard Catalyst Profiles

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Meredith Anne Skiba, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Suomivuori CM, Latorraca NR, Wingler LM, Eismann S, King MC, Kleinhenz ALW, Skiba MA, Staus DP, Kruse AC, Lefkowitz RJ, Dror RO. Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor. Science. 2020 02 21; 367(6480):881-887. PMID: 32079767.
    Citations:    
  2. Wingler LM, Skiba MA, McMahon C, Staus DP, Kleinhenz ALW, Suomivuori CM, Latorraca NR, Dror RO, Lefkowitz RJ, Kruse AC. Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR. Science. 2020 02 21; 367(6480):888-892. PMID: 32079768.
    Citations:    
  3. Skiba MA, Tran CL, Dan Q, Sikkema AP, Klaver Z, Gerwick WH, Sherman DH, Smith JL. Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis. Structure. 2020 01 07; 28(1):63-74.e4. PMID: 31785925.
    Citations:    
  4. Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Structural Basis of Polyketide Synthase O-Methylation. ACS Chem Biol. 2018 12 21; 13(12):3221-3228. PMID: 30489068.
    Citations:    Fields:    
  5. Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. ACS Chem Biol. 2018 06 15; 13(6):1640-1650. PMID: 29701944.
    Citations: 1     Fields:    
  6. Skiba MA, Maloney FP, Dan Q, Fraley AE, Aldrich CC, Smith JL, Brown WC. PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production. Methods Enzymol. 2018; 604:45-88. PMID: 29779664.
    Citations: 1     Fields:    
  7. Chun SW, Hinze ME, Skiba MA, Narayan ARH. Chemistry of a Unique Polyketide-like Synthase. J Am Chem Soc. 2018 02 21; 140(7):2430-2433. PMID: 29390180.
    Citations: 2     Fields:    Translation:Cells
  8. Skiba MA, Sikkema AP, Moss NA, Tran CL, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit. ACS Chem Biol. 2017 12 15; 12(12):3039-3048. PMID: 29096064.
    Citations: 3     Fields:    Translation:Cells
  9. Motl N, Skiba MA, Kabil O, Smith JL, Banerjee R. Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J Biol Chem. 2017 08 25; 292(34):14026-14038. PMID: 28684420.
    Citations: 2     Fields:    Translation:Cells
  10. Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, Skiba MA, Maloney FP, Beinlich FR, Popovic Z, Baker D, Khatib F, Bardwell JC. Corrigendum: Determining crystal structures through crowdsourcing and coursework. Nat Commun. 2016 10 25; 7:13392. PMID: 27779204.
    Citations:    Fields:    
  11. Skiba MA, Sikkema AP, Fiers WD, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase. ACS Chem Biol. 2016 12 16; 11(12):3319-3327. PMID: 27723289.
    Citations: 8     Fields:    Translation:Cells
  12. Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, Skiba MA, Maloney FP, Beinlich FR, Popovic Z, Baker D, Khatib F, Bardwell JC. Determining crystal structures through crowdsourcing and coursework. Nat Commun. 2016 09 16; 7:12549. PMID: 27633552.
    Citations: 4     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.