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Tyler S Beyett, Ph.D.

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  1. F32CA247198 (BEYETT, TYLER STEVEN) Jun 4, 2020
    NIH/NCI
    Studies of mutant-selective allosteric inhibitors of EGFR for non-small cell lung cancer
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Beyett TS, Chen Q, Labudde EJ, Krampen J, Sharma PV, Tesmer JJG. Characterization of a hyperphosphorylated variant of G protein-coupled receptor kinase 5 expressed in E. coli. Protein Expr Purif. 2020 04; 168:105547. PMID: 31786308.
    Citations:    
  2. Beyett TS, Fraley AE, Labudde E, Patra D, Coleman RC, Eguchi A, Glukhova A, Chen Q, Williams RM, Koch WJ, Sherman DH, Tesmer JJG. Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe. Proc Natl Acad Sci U S A. 2019 08 06; 116(32):15895-15900. PMID: 31337679.
    Citations:    
  3. Heppner DE, Beyett TS, Eck MJ. A driving test for oncogenic mutations. J Biol Chem. 2019 06 14; 294(24):9390-9391. PMID: 31201242.
    Citations:    
  4. Gan X, Wilson MW, Beyett TS, Wen B, Sun D, Larsen SD, Tesmer JJG, Saltiel AR, Showalter HD. Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes. J Labelled Comp Radiopharm. 2019 05 15; 62(5):202-208. PMID: 30828860.
    Citations:    
  5. Beyett TS, Gan X, Reilly SM, Gomez AV, Chang L, Tesmer JJG, Saltiel AR, Showalter HD. Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKe for the treatment of obesity. Bioorg Med Chem. 2018 11 01; 26(20):5443-5461. PMID: 30270002.
    Citations:    Fields:    
  6. Beyett TS, Gan X, Reilly SM, Chang L, Gomez AV, Saltiel AR, Showalter HD, Tesmer JJG. Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKe and Reveal Mechanisms for Selective Inhibition. Mol Pharmacol. 2018 10; 94(4):1210-1219. PMID: 30082428.
    Citations:    Fields:    
  7. Yao XQ, Cato MC, Labudde E, Beyett TS, Tesmer JJG, Grant BJ. Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation. J Biol Chem. 2017 09 29; 292(39):16032-16043. PMID: 28808053.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  8. Beyett TS, Bandekar SB, Tesmer JJG. G Protein-Coupled Receptor Kinases. Molecular Basis for Targeting, Inhibition, and Receptor Phosphorylation in the G Protein-Coupled Receptor Kinase 4 Subfamily. 2016; 59-74. View Publication.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.