Harvard Catalyst Profiles

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Sophie Sebille, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Florence X, Sebille S, Tullio Pd, Lebrun P, Pirotte B. New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position. Bioorg Med Chem. 2009 Nov 15; 17(22):7723-31. PMID: 19822435.
    Citations: 1     Fields:    Translation:Animals
  2. Sebille S, de Tullio P, Florence X, Becker B, Antoine MH, Michaux C, Wouters J, Pirotte B, Lebrun P. New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers. Bioorg Med Chem. 2008 May 15; 16(10):5704-19. PMID: 18406154.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Sebille S, Gall D, de Tullio P, Florence X, Lebrun P, Pirotte B. Design, synthesis, and pharmacological evaluation of R/S-3,4-dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2H-1-benzopyrans: toward tissue-selective pancreatic beta-cell KATP channel openers structurally related to (+/-)-cromakalim. J Med Chem. 2006 Jul 27; 49(15):4690-7. PMID: 16854075.
    Citations: 3     Fields:    Translation:AnimalsCells
  4. de Tullio P, Boverie S, Becker B, Antoine MH, Nguyen QA, Francotte P, Counerotte S, Sebille S, Pirotte B, Lebrun P. 3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers: effect of 6,7-disubstitution on potency and tissue selectivity. J Med Chem. 2005 Jul 28; 48(15):4990-5000. PMID: 16033278.
    Citations: 1     Fields:    Translation:AnimalsCells
  5. Boverie S, Antoine MH, Somers F, Becker B, Sebille S, Ouedraogo R, Counerotte S, Pirotte B, Lebrun P, de Tullio P. Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides. J Med Chem. 2005 May 19; 48(10):3492-503. PMID: 15887958.
    Citations: 3     Fields:    Translation:AnimalsCells
  6. Sebille S, de Tullio P, Becker B, Antoine MH, Boverie S, Pirotte B, Lebrun P. 4,6-Disubstituted 2,2-dimethylchromans structurally related to the K(ATP) channel opener cromakalim: design, synthesis, and effect on insulin release and vascular tone. J Med Chem. 2005 Jan 27; 48(2):614-21. PMID: 15658874.
    Citations:    Fields:    Translation:AnimalsCells
  7. de Tullio P, Becker B, Boverie S, Dabrowski M, Wahl P, Antoine MH, Somers F, Sebille S, Ouedraogo R, Hansen JB, Lebrun P, Pirotte B. Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides. J Med Chem. 2003 Jul 17; 46(15):3342-53. PMID: 12852765.
    Citations: 1     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.