Harvard Catalyst Profiles

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Anastasia Shindyapina, Ph.D.


Young Investigator Award for Outstanding Contribution in Science
2015 - 2017
Presidential Fellowship for Young Investigators

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Shindyapina AV, Cho Y, Kaya A, Tyshkovskiy A, Castro JP, Deik A, Gordevicius J, Poganik JR, Clish CB, Horvath S, Peshkin L, Gladyshev VN. Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna. Sci Adv. 2022 09 16; 8(37):eabo5482. PMID: 36112674; PMCID: PMC9481125.
    Citations: 1     Fields:    Translation:Animals
  2. Walsh K, Raghavachari N, Kerr C, Bick AG, Cummings SR, Druley T, Dunbar CE, Genovese G, Goodell MA, Jaiswal S, Maciejewski J, Natarajan P, Shindyapina AV, Shuldiner AR, Van Den Akker EB, Vijg J. Clonal Hematopoiesis Analyses in Clinical, Epidemiologic, and Genetic Aging Studies to Unravel Underlying Mechanisms of Age-Related Dysfunction in Humans. Front Aging. 2022; 3:841796. PMID: 35821803; PMCID: PMC9261374.
  3. Ying K, Zhai R, Pyrkov TV, Shindyapina AV, Mariotti M, Fedichev PO, Shen X, Gladyshev VN. Genetic and phenotypic analysis of the causal relationship between aging and COVID-19. Commun Med (Lond). 2021; 1:35. PMID: 35602207; PMCID: PMC9053191.
    Citations: 3     
  4. Santesmasses D, Castro JP, Zenin AA, Shindyapina AV, Gerashchenko MV, Zhang B, Kerepesi C, Yim SH, Fedichev PO, Gladyshev VN. COVID-19 is an emergent disease of aging. Aging Cell. 2020 10; 19(10):e13230. PMID: 33006233.
    Citations: 47     Fields:    Translation:HumansCellsPHPublic Health
  5. Shindyapina AV, Zenin AA, Tarkhov AE, Santesmasses D, Fedichev PO, Gladyshev VN. Germline burden of rare damaging variants negatively affects human healthspan and lifespan. Elife. 2020 04 07; 9. PMID: 32254024.
    Citations: 5     Fields:    Translation:HumansCells
  6. Komarova TV, Sheshukova EV, Kosobokova EN, Kosorukov VS, Shindyapina AV, Lipskerov FA, Shpudeiko PS, Byalik TE, Dorokhov YL. The biological activity of bispecific trastuzumab/pertuzumab plant biosimilars may be drastically boosted by disulfiram increasing formaldehyde accumulation in cancer cells. Sci Rep. 2019 11 07; 9(1):16168. PMID: 31700025.
    Citations: 2     Fields:    Translation:HumansCells
  7. Sheshukova EV, Komarova TV, Ershova NM, Shindyapina AV, Dorokhov YL. An Alternative Nested Reading Frame May Participate in the Stress-Dependent Expression of a Plant Gene. Front Plant Sci. 2017; 8:2137. PMID: 29312392; PMCID: PMC5742262.
    Citations: 1     
  8. Shindyapina AV, Komarova TV, Sheshukova EV, Ershova NM, Tashlitsky VN, Kurkin AV, Yusupov IR, Mkrtchyan GV, Shagidulin MY, Dorokhov YL. The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals. Front Neurosci. 2017; 11:651. PMID: 29249928; PMCID: PMC5717020.
    Citations: 6     
  9. Sheshukova EV, Komarova TV, Pozdyshev DV, Ershova NM, Shindyapina AV, Tashlitsky VN, Sheval EV, Dorokhov YL. The Intergenic Interplay between Aldose 1-Epimerase-Like Protein and Pectin Methylesterase in Abiotic and Biotic Stress Control. Front Plant Sci. 2017; 8:1646. PMID: 28993784; PMCID: PMC5622589.
    Citations: 10     
  10. Dorokhov YL, Sheshukova EV, Kosobokova EN, Shindyapina AV, Kosorukov VS, Komarova TV. Functional Role of Carbohydrate Residues in Human Immunoglobulin G and Therapeutic Monoclonal Antibodies. Biochemistry (Mosc). 2016 Aug; 81(8):835-57. PMID: 27677552.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Sheshukova EV, Shindyapina AV, Komarova TV, Dorokhov YL. ["Matreshka" Genes with Alternative Reading Frames]. Genetika. 2016 Feb; 52(2):146-63. PMID: 27215029.
    Citations:    Fields:    Translation:HumansCells
  12. Dorokhov YL, Shindyapina AV, Sheshukova EV, Komarova TV. Metabolic methanol: molecular pathways and physiological roles. Physiol Rev. 2015 Apr; 95(2):603-44. PMID: 25834233.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  13. Shindyapina AV, Petrunia IV, Komarova TV, Sheshukova EV, Kosorukov VS, Kiryanov GI, Dorokhov YL. Dietary methanol regulates human gene activity. PLoS One. 2014; 9(7):e102837. PMID: 25033451.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  14. Shindyapina AV, Mkrtchyan GV, Gneteeva T, Buiucli S, Tancowny B, Kulka M, Aliper A, Zhavoronkov A. Mineralization of the connective tissue: a complex molecular process leading to age-related loss of function. Rejuvenation Res. 2014 Apr; 17(2):116-33. PMID: 23902273.
    Citations: 3     Fields:    Translation:HumansAnimals
  15. Komarova TV, Petrunia IV, Shindyapina AV, Silachev DN, Sheshukova EV, Kiryanov GI, Dorokhov YL. Endogenous methanol regulates mammalian gene activity. PLoS One. 2014; 9(2):e90239. PMID: 24587296.
    Citations: 10     Fields:    Translation:Animals
  16. Dorokhov YL, Komarova TV, Petrunia IV, Kosorukov VS, Zinovkin RA, Shindyapina AV, Frolova OY, Gleba YY. Methanol may function as a cross-kingdom signal. PLoS One. 2012; 7(4):e36122. PMID: 22563443.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.