Harvard Catalyst Profiles

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Lena O'Keefe, M.D.

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  1. O'Keefe LM, Conway SE, Czap A, Malchoff CD, Benashski S, Fortunato G, Staff I, McCullough LD. Thyroid hormones and functional outcomes after ischemic stroke. Thyroid Res. 2015; 8:9. PMID: 26157487; PMCID: PMC4495802.
  2. Venna VR, Verma R, O'Keefe LM, Xu Y, Crapser J, Friedler B, McCullough LD. Inhibition of mitochondrial p53 abolishes the detrimental effects of social isolation on ischemic brain injury. Stroke. 2014 Oct; 45(10):3101-4. PMID: 25205311; PMCID: PMC4192598.
  3. O'Keefe LM, Doran SJ, Mwilambwe-Tshilobo L, Conti LH, Venna VR, McCullough LD. Social isolation after stroke leads to depressive-like behavior and decreased BDNF levels in mice. Behav Brain Res. 2014 Mar 01; 260:162-70. PMID: 24211537; PMCID: PMC4225130.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.