Harvard Catalyst Profiles

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Haopeng Xiao, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Darabedian N, Ji W, Fan M, Lin S, Seo HS, Vinogradova EV, Yaron TM, Mills EL, Xiao H, Senkane K, Huntsman EM, Johnson JL, Che J, Cantley LC, Cravatt BF, Dhe-Paganon S, Stegmaier K, Zhang T, Gray NS, Chouchani ET. Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nat Chem Biol. 2023 Feb 23. PMID: 36823351.
    Citations:    Fields:    
  2. Devant P, Boršic E, Ngwa EM, Xiao H, Chouchani ET, Thiagarajah JR, Hafner-Bratkovic I, Evavold CL, Kagan JC. Gasdermin D pore-forming activity is redox-sensitive. Cell Rep. 2023 01 31; 42(1):112008. PMID: 36662620; PMCID: PMC9947919.
    Citations: 1     Fields:    Translation:Cells
  3. Mittenbühler MJ, Jedrychowski MP, Van Vranken JG, Sprenger HG, Wilensky S, Dumesic PA, Sun Y, Tartaglia A, Bogoslavski D, A M, Xiao H, Blackmore KA, Reddy A, Gygi SP, Chouchani ET, Spiegelman BM. Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues. Cell Metab. 2023 Jan 14. PMID: 36681077.
    Citations:    Fields:    
  4. Xiao H, Bozi LHM, Sun Y, Riley CL, Philip VM, Chen M, Li J, Zhang T, Mills EL, Emont MP, Sun W, Reddy A, Garrity R, Long J, Becher T, Vitas LP, Laznik-Bogoslavski D, Ordonez M, Liu X, Chen X, Wang Y, Liu W, Tran N, Liu Y, Zhang Y, Cypess AM, White AP, He Y, Deng R, Schöder H, Paulo JA, Jedrychowski MP, Banks AS, Tseng YH, Cohen P, Tsai LT, Rosen ED, Klein S, Chondronikola M, McAllister FE, Van Bruggen N, Huttlin EL, Spiegelman BM, Churchill GA, Gygi SP, Chouchani ET. Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. Cell. 2022 11 23; 185(24):4654-4673.e28. PMID: 36334589.
    Citations: 1     Fields:    Translation:HumansAnimals
  5. Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, Chouchani ET. Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation. Cell Metab. 2022 01 04; 34(1):140-157.e8. PMID: 34861155; PMCID: PMC8732317.
    Citations: 4     Fields:    Translation:Animals
  6. Mills EL, Harmon C, Jedrychowski MP, Xiao H, Garrity R, Tran NV, Bradshaw GA, Fu A, Szpyt J, Reddy A, Prendeville H, Danial NN, Gygi SP, Lynch L, Chouchani ET. UCP1 governs liver extracellular succinate and inflammatory pathogenesis. Nat Metab. 2021 05; 3(5):604-617. PMID: 34002097; PMCID: PMC8207988.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  7. Yan S, Kumari M, Xiao H, Jacobs C, Kochumon S, Jedrychowski M, Chouchani E, Ahmad R, Rosen ED. IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis. J Clin Invest. 2021 04 01; 131(7). PMID: 33571167; PMCID: PMC8011904.
    Citations: 8     Fields:    Translation:AnimalsCells
  8. Mills EL, Xiao H, Chouchani ET. AIDA and UCP1 snuggle up to prevent hypothermia. Nat Cell Biol. 2021 03; 23(3):216-218. PMID: 33723427.
    Citations:    Fields:    Translation:Humans
  9. Reddy A, Bozi LHM, Yaghi OK, Mills EL, Xiao H, Nicholson HE, Paschini M, Paulo JA, Garrity R, Laznik-Bogoslavski D, Ferreira JCB, Carl CS, Sjøberg KA, Wojtaszewski JFP, Jeppesen JF, Kiens B, Gygi SP, Richter EA, Mathis D, Chouchani ET. pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise. Cell. 2020 10 01; 183(1):62-75.e17. PMID: 32946811; PMCID: PMC7778787.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  10. Yu Q, Xiao H, Jedrychowski MP, Schweppe DK, Navarrete-Perea J, Knott J, Rogers J, Chouchani ET, Gygi SP. Sample multiplexing for targeted pathway proteomics in aging mice. Proc Natl Acad Sci U S A. 2020 05 05; 117(18):9723-9732. PMID: 32332170.
    Citations: 18     Fields:    Translation:Animals
  11. Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, Paulo JA, Zhang T, Gray NS, Gygi SP, Chouchani ET. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. 2020 03 05; 180(5):968-983.e24. PMID: 32109415.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  12. Nguyen DC, Garimalla S, Xiao H, Kyu S, Albizua I, Galipeau J, Chiang KY, Waller EK, Wu R, Gibson G, Roberson J, Lund FE, Randall TD, Sanz I, Lee FE. Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion. Nat Commun. 2018 09 12; 9(1):3698. PMID: 30209264.
    Citations: 42     Fields:    Translation:HumansCells
  13. Xiao H, Suttapitugsakul S, Sun F, Wu R. Mass Spectrometry-Based Chemical and Enzymatic Methods for Global Analysis of Protein Glycosylation. Acc Chem Res. 2018 08 21; 51(8):1796-1806. PMID: 30011186; PMCID: PMC6118346.
    Citations: 27     Fields:    Translation:HumansCells
  14. Xiao H, Chen W, Smeekens JM, Wu R. An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins. Nat Commun. 2018 04 27; 9(1):1692. PMID: 29703890.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  15. Nguyen DC, Lewis HC, Joyner C, Warren V, Xiao H, Kissick HT, Wu R, Galipeau J, Lee FE. Extracellular vesicles from bone marrow-derived mesenchymal stromal cells support ex vivo survival of human antibody secreting cells. J Extracell Vesicles. 2018; 7(1):1463778. PMID: 29713426.
    Citations: 17     Fields:    
  16. Suttapitugsakul S, Xiao H, Smeekens J, Wu R. Evaluation and optimization of reduction and alkylation methods to maximize peptide identification with MS-based proteomics. Mol Biosyst. 2017 Nov 21; 13(12):2574-2582. PMID: 29019370; PMCID: PMC5698164.
    Citations: 14     Fields:    Translation:Cells
  17. Xiao H, Wu R. Simultaneous Quantitation of Glycoprotein Degradation and Synthesis Rates by Integrating Isotope Labeling, Chemical Enrichment, and Multiplexed Proteomics. Anal Chem. 2017 10 03; 89(19):10361-10367. PMID: 28850217; PMCID: PMC5678942.
    Citations: 10     Fields:    Translation:HumansCells
  18. Zhang M, Matyunina LV, Walker LD, Chen W, Xiao H, Benigno BB, Wu R, McDonald JF. Evidence for the importance of post-transcriptional regulatory changes in ovarian cancer progression and the contribution of miRNAs. Sci Rep. 2017 08 15; 7(1):8171. PMID: 28811560.
    Citations: 6     Fields:    Translation:HumansCells
  19. Ali MRK, Wu Y, Tang Y, Xiao H, Chen K, Han T, Fang N, Wu R, El-Sayed MA. Targeting cancer cell integrins using gold nanorods in photothermal therapy inhibits migration through affecting cytoskeletal proteins. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5655-E5663. PMID: 28652358; PMCID: PMC5514737.
    Citations: 40     Fields:    Translation:HumansCells
  20. Xiao H, Hwang JE, Wu R. Mass spectrometric analysis of the N-glycoproteome in statin-treated liver cells with two lectin-independent chemical enrichment methods. Int J Mass Spectrom. 2018 Jun; 429:66-75. PMID: 30147434; PMCID: PMC6103449.
    Citations: 6     
  21. Zheng J, Xiao H, Wu R. Specific Identification of Glycoproteins Bearing the Tn Antigen in Human Cells. Angew Chem Int Ed Engl. 2017 06 12; 56(25):7107-7111. PMID: 28514044; PMCID: PMC5529048.
    Citations: 21     Fields:    Translation:HumansCells
  22. Ali MR, Rahman MA, Wu Y, Han T, Peng X, Mackey MA, Wang D, Shin HJ, Chen ZG, Xiao H, Wu R, Tang Y, Shin DM, El-Sayed MA. Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):E3110-E3118. PMID: 28356516; PMCID: PMC5393247.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  23. Xiao H, Wu R. Global and Site-Specific Analysis Revealing Unexpected and Extensive Protein S-GlcNAcylation in Human Cells. Anal Chem. 2017 03 21; 89(6):3656-3663. PMID: 28234450.
    Citations: 11     Fields:    Translation:HumansCells
  24. Smeekens JM, Xiao H, Wu R. Global Analysis of Secreted Proteins and Glycoproteins in Saccharomyces cerevisiae. J Proteome Res. 2017 02 03; 16(2):1039-1049. PMID: 27933904.
    Citations: 14     Fields:    Translation:AnimalsCells
  25. Ali MR, Wu Y, Han T, Zang X, Xiao H, Tang Y, Wu R, Fernández FM, El-Sayed MA. Simultaneous Time-Dependent Surface-Enhanced Raman Spectroscopy, Metabolomics, and Proteomics Reveal Cancer Cell Death Mechanisms Associated with Gold Nanorod Photothermal Therapy. J Am Chem Soc. 2016 11 30; 138(47):15434-15442. PMID: 27809520.
    Citations: 25     Fields:    Translation:HumansCells
  26. Xiao H, Wu R. Quantitative investigation of human cell surface N-glycoprotein dynamics. Chem Sci. 2017 Jan 01; 8(1):268-277. PMID: 28616130; PMCID: PMC5458730.
    Citations: 26     
  27. Xiao H, Smeekens JM, Wu R. Quantification of tunicamycin-induced protein expression and N-glycosylation changes in yeast. Analyst. 2016 Jun 21; 141(12):3737-45. PMID: 27007503.
    Citations: 14     Fields:    Translation:AnimalsCells
  28. Xiao H, Tang GX, Wu R. Site-Specific Quantification of Surface N-Glycoproteins in Statin-Treated Liver Cells. Anal Chem. 2016 Mar 15; 88(6):3324-32. PMID: 26894747.
    Citations: 23     Fields:    Translation:HumansCells
  29. Xiao H, Chen W, Tang GX, Smeekens JM, Wu R. Systematic investigation of cellular response and pleiotropic effects in atorvastatin-treated liver cells by MS-based proteomics. J Proteome Res. 2015 Mar 06; 14(3):1600-11. PMID: 25668447.
    Citations: 4     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.