Harvard Catalyst Profiles

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Amit K Gandhi, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gandhi AK, Sun ZJ, Huang YH, Kim WM, Yang C, Petsko GA, Beauchemin N, Blumberg RS. Structural analysis of human CEACAM1 oligomerization. Commun Biol. 2022 09 30; 5(1):1042. PMID: 36180783; PMCID: PMC9525683.
    Citations:    Translation:HumansCells
  2. Gandhi AK, Sun ZJ, Kim WM, Huang YH, Kondo Y, Bonsor DA, Sundberg EJ, Wagner G, Kuchroo VK, Petsko GA, Blumberg RS. Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol. 2021 03 19; 4(1):360. PMID: 33742094; PMCID: PMC7979749.
    Citations: 3     Translation:HumansCells
  3. Hubbard JJ, Pyzik M, Rath T, Kozicky LK, Sand KMK, Gandhi AK, Grevys A, Foss S, Menzies SC, Glickman JN, Fiebiger E, Roopenian DC, Sandlie I, Andersen JT, Sly LM, Baker K, Blumberg RS. FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity. J Exp Med. 2020 10 05; 217(10). PMID: 32658257.
    Citations: 5     Fields:    Translation:HumansAnimals
  4. Kim WM, Huang YH, Gandhi A, Blumberg RS. CEACAM1 structure and function in immunity and its therapeutic implications. Semin Immunol. 2019 04; 42:101296. PMID: 31604530; PMCID: PMC6814268.
    Citations: 18     Fields:    Translation:HumansAnimals
  5. Gandhi AK, Kim WM, Sun ZJ, Huang YH, Bonsor DA, Sundberg EJ, Kondo Y, Wagner G, Kuchroo VK, Petsko G, Blumberg RS. High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3. Sci Rep. 2018 11 30; 8(1):17512. PMID: 30504845.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  6. Iyer SS, Gensollen T, Gandhi A, Oh SF, Neves JF, Collin F, Lavin R, Serra C, Glickman J, de Silva PSA, Sartor RB, Besra G, Hauser R, Maxwell A, Llebaria A, Blumberg RS. Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. Cell. 2018 05 17; 173(5):1123-1134.e11. PMID: 29775592.
    Citations: 40     Fields:    Translation:AnimalsCells
  7. Pyzik M, Rath T, Kuo TT, Win S, Baker K, Hubbard JJ, Grenha R, Gandhi A, Krämer TD, Mezo AR, Taylor ZS, McDonnell K, Nienaber V, Andersen JT, Mizoguchi A, Blumberg L, Purohit S, Jones SD, Christianson G, Lencer WI, Sandlie I, Kaplowitz N, Roopenian DC, Blumberg RS. Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):E2862-E2871. PMID: 28330995; PMCID: PMC5389309.
    Citations: 39     Fields:    Translation:AnimalsCells
  8. Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 2016 08 18; 536(7616):359. PMID: 26982724; PMCID: PMC5110397.
    Citations: 18     Fields:    
  9. Remesh SG, Ghatge MS, Ahmed MH, Musayev FN, Gandhi A, Chowdhury N, di Salvo ML, Kellogg GE, Contestabile R, Schirch V, Safo MK. Molecular basis of E. coli L-threonine aldolase catalytic inactivation at low pH. Biochim Biophys Acta. 2015 Apr; 1854(4):278-83. PMID: 25560296; PMCID: PMC4323617.
    Citations: 2     Fields:    Translation:Cells
  10. Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. 2015 01 15; 517(7534):386-90. PMID: 25363763; PMCID: PMC4297519.
    Citations: 237     Fields:    Translation:HumansAnimalsCells
  11. Ghatge MS, Contestabile R, di Salvo ML, Desai JV, Gandhi AK, Camara CM, Florio R, González IN, Parroni A, Schirch V, Safo MK. Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase. PLoS One. 2012; 7(7):e41680. PMID: 22848564.
    Citations: 13     Fields:    Translation:HumansCells
  12. Gandhi AK, Desai JV, Ghatge MS, di Salvo ML, Di Biase S, Danso-Danquah R, Musayev FN, Contestabile R, Schirch V, Safo MK. Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. PLoS One. 2012; 7(7):e40954. PMID: 22879864.
    Citations: 9     Fields:    Translation:Humans
  13. Gandhi A, Lakshminarasimhan D, Sun Y, Guo HC. Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1. Sci Rep. 2011; 1:186. PMID: 22355701.
    Citations: 18     Fields:    Translation:HumansCells
  14. Gandhi AK, Ghatge MS, Musayev FN, Sease A, Aboagye SO, di Salvo ML, Schirch V, Safo MK. Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase. Biochem Biophys Res Commun. 2009 Mar 27; 381(1):12-5. PMID: 19351586.
    Citations: 6     Fields:    Translation:HumansCells
  15. Musayev FN, di Salvo ML, Ko TP, Gandhi AK, Goswami A, Schirch V, Safo MK. Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. Protein Sci. 2007 Oct; 16(10):2184-94. PMID: 17766369; PMCID: PMC2204131.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.