Harvard Catalyst Profiles

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Mark J. O'Connor, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ge T, Irvin MR, Patki A, Srinivasasainagendra V, Lin YF, Tiwari HK, Armstrong ND, Benoit B, Chen CY, Choi KW, Cimino JJ, Davis BH, Dikilitas O, Etheridge B, Feng YA, Gainer V, Huang H, Jarvik GP, Kachulis C, Kenny EE, Khan A, Kiryluk K, Kottyan L, Kullo IJ, Lange C, Lennon N, Leong A, Malolepsza E, Miles AD, Murphy S, Namjou B, Narayan R, O'Connor MJ, Pacheco JA, Perez E, Rasmussen-Torvik LJ, Rosenthal EA, Schaid D, Stamou M, Udler MS, Wei WQ, Weiss ST, Ng MCY, Smoller JW, Lebo MS, Meigs JB, Limdi NA, Karlson EW. Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Med. 2022 06 29; 14(1):70. PMID: 35765100; PMCID: PMC9241245.
    Citations: 1     Fields:    Translation:Humans
  2. O'Connor MJ, Schroeder P, Huerta-Chagoya A, Cortés-Sánchez P, Bonàs-Guarch S, Guindo-Martínez M, Cole JB, Kaur V, Torrents D, Veerapen K, Grarup N, Kurki M, Rundsten CF, Pedersen O, Brandslund I, Linneberg A, Hansen T, Leong A, Florez JC, Mercader JM. Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes. Diabetes. 2022 03 01; 71(3):554-565. PMID: 34862199; PMCID: PMC8893948.
    Citations: 2     Fields:    Translation:Humans
  3. McCormick N, O'Connor MJ, Yokose C, Merriman TR, Mount DB, Leong A, Choi HK. Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization. Arthritis Rheumatol. 2021 11; 73(11):2096-2104. PMID: 33982892; PMCID: PMC8568618.
    Citations: 12     Fields:    Translation:Humans
  4. Lloyd RL, Urban V, Muñoz-Martínez F, Ayestaran I, Thomas JC, de Renty C, O'Connor MJ, Forment JV, Galanty Y, Jackson SP. Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress. Nucleic Acids Res. 2021 09 07; 49(15):8665-8683. PMID: 34329458.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  5. Gill SJ, Wijnhoven PWG, Fok JHL, Lloyd RL, Cairns J, Armenia J, Nikkilä J, Lau A, Bakkenist CJ, Galbraith SM, Vens C, O'Connor MJ. Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development. Mol Cancer Ther. 2021 09; 20(9):1614-1626. PMID: 34158341; PMCID: PMC8650722.
    Citations: 5     Fields:    Translation:HumansCells
  6. Jiang Y, Martin J, Alkadhimi M, Shigemori K, Kinchesh P, Gilchrist S, Kersemans V, Smart S, Thompson JM, Hill MA, O'Connor MJ, Davies BR, Ryan AJ. Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model. Br J Cancer. 2021 05; 124(11):1809-1819. PMID: 33742147; PMCID: PMC8144220.
    Citations: 1     Fields:    Translation:Animals
  7. Winkler C, Armenia J, Jones GN, Tobalina L, Sale MJ, Petreus T, Baird T, Serra V, Wang AT, Lau A, Garnett MJ, Jaaks P, Coker EA, Pierce AJ, O'Connor MJ, Leo E. SLFN11 informs on standard of care and novel treatments in a wide range of cancer models. Br J Cancer. 2021 03; 124(5):951-962. PMID: 33339894.
    Citations: 23     Fields:    Translation:HumansAnimals
  8. Tran Chau V, Liu W, Gerbé de Thoré M, Meziani L, Mondini M, O'Connor MJ, Deutsch E, Clémenson C. Differential therapeutic effects of PARP and ATR inhibition combined with radiotherapy in the treatment of subcutaneous versus orthotopic lung tumour models. Br J Cancer. 2020 09; 123(5):762-771. PMID: 32546832; PMCID: PMC7463250.
    Citations: 6     Fields:    Translation:AnimalsCells
  9. Gomez MK, Illuzzi G, Colomer C, Churchman M, Hollis RL, O'Connor MJ, Gourley C, Leo E, Melton DW. Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells. Cancers (Basel). 2020 Jun 09; 12(6). PMID: 32526907.
    Citations: 6     
  10. Borst GR, Kumareswaran R, Yücel H, Telli S, Do T, McKee T, Zafarana G, Jonkers J, Verheij M, O'Connor MJ, Rottenberg S, Bristow RG. Correction: Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model. Oncotarget. 2020 Apr 28; 11(17):1573-1574. PMID: 32391125; PMCID: PMC7197446.
    Citations:    Fields:    
  11. O'Connor MJ, Snyder EA, Hayes FJ. Klinefelter Syndrome and Diabetes. Curr Diab Rep. 2019 07 31; 19(9):71. PMID: 31367971.
    Citations: 12     Fields:    Translation:Humans
  12. O'Connor L, Kue RC, O'Connor MJ. Characteristics of Patients with Recurrent Emergency Medical Services Utilization for Symptomatic Hypoglycemia in an Urban Setting. Prehosp Emerg Care. 2019 Nov-Dec; 23(6):780-787. PMID: 30893563.
    Citations: 3     Fields:    Translation:Humans
  13. Ambrus DB, O'Connor MJ. Things We Do For No Reason: Sliding-Scale Insulin as Monotherapy for Glycemic Control in Hospitalized Patients. J Hosp Med. 2019 02 01; 14(2):114-116. PMID: 30534639.
    Citations: 5     Fields:    Translation:Humans
  14. O'Connor L, Rebesco M, Robinson C, Gross K, Castellana A, O'Connor MJ, Restuccia M. Outcomes of Prehospital Chemical Sedation With Ketamine Versus Haloperidol and Benzodiazepine or Physical Restraint Only. Prehosp Emerg Care. 2019 Mar-Apr; 23(2):201-209. PMID: 30118360.
    Citations: 8     Fields:    Translation:Humans
  15. Dezieck L, Hafez Z, Conicella A, Blohm E, O'Connor MJ, Schwarz ES, Mullins ME. Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Clin Toxicol (Phila). 2017 Sep; 55(8):908-913. PMID: 28494183.
    Citations: 16     Fields:    Translation:Humans
  16. O'Connor M, Dunbar N. Bayesian Analysis of Blood Transfusion in Dracula. Ir Med J. 2016 Feb 19; 109(2):362. PMID: 27685695.
    Citations:    Fields:    
  17. O'Connor MJ, Hauser AE, Haberman AM, Kleinstein SH. Activated germinal centre B cells undergo directed migration. Int J Data Min Bioinform. 2011; 5(3):321-31. PMID: 21805826.
    Citations: 1     Fields:    Translation:Cells
  18. Zimmermann H, Koh CH, Degenkolbe R, O'Connor MJ, Müller A, Steger G, Chen JJ, Lui Y, Androphy E, Bernard HU. Interaction with CBP/p300 enables the bovine papillomavirus type 1 E6 oncoprotein to downregulate CBP/p300-mediated transactivation by p53. J Gen Virol. 2000 Nov; 81(Pt 11):2617-2623. PMID: 11038372.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.