Harvard Catalyst Profiles

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Jonathan Garrett Van Vranken, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mitchell DC, Kuljanin M, Li J, Van Vranken JG, Bulloch N, Schweppe DK, Huttlin EL, Gygi SP. A proteome-wide atlas of drug mechanism of action. Nat Biotechnol. 2023 Jan 02. PMID: 36593396.
    Citations:    Fields:    
  2. Kam TI, Park H, Chou SC, Van Vranken JG, Mittenbühler MJ, Kim H, A M, Choi YR, Biswas D, Wang J, Shin Y, Loder A, Karuppagounder SS, Wrann CD, Dawson VL, Spiegelman BM, Dawson TM. Amelioration of pathologic a-synuclein-induced Parkinson's disease by irisin. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2204835119. PMID: 36044549; PMCID: PMC9457183.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Van Vranken JG, Li J, Mitchell DC, Navarrete-Perea J, Gygi SP. Assessing target engagement using proteome-wide solvent shift assays. Elife. 2021 12 08; 10. PMID: 34878405; PMCID: PMC8654358.
    Citations: 1     Fields:    Translation:HumansCells
  4. Navarrete-Perea J, Guerra-Moreno A, Van Vranken J, Isasa M, Paulo JA, Gygi SP. Iron Deficiency and Recovery in Yeast: A Quantitative Proteomics Approach. J Proteome Res. 2021 05 07; 20(5):2751-2761. PMID: 33797912; PMCID: PMC8210944.
    Citations:    Fields:    Translation:HumansAnimals
  5. Li J, Van Vranken JG, Paulo JA, Huttlin EL, Gygi SP. Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay. J Proteome Res. 2020 05 01; 19(5):2159-2166. PMID: 32243163; PMCID: PMC7294736.
    Citations: 5     Fields:    
  6. Li J, Van Vranken JG, Pontano Vaites L, Schweppe DK, Huttlin EL, Etienne C, Nandhikonda P, Viner R, Robitaille AM, Thompson AH, Kuhn K, Pike I, Bomgarden RD, Rogers JC, Gygi SP, Paulo JA. TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples. Nat Methods. 2020 04; 17(4):399-404. PMID: 32203386.
    Citations: 76     Fields:    Translation:HumansCells
  7. Nowinski SM, Van Vranken JG, Dove KK, Rutter J. Impact of Mitochondrial Fatty Acid Synthesis on Mitochondrial Biogenesis. Curr Biol. 2018 10 22; 28(20):R1212-R1219. PMID: 30352195; PMCID: PMC6258005.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  8. Van Vranken JG, Nowinski SM, Clowers KJ, Jeong MY, Ouyang Y, Berg JA, Gygi JP, Gygi SP, Winge DR, Rutter J. ACP Acylation Is an Acetyl-CoA-Dependent Modification Required for Electron Transport Chain Assembly. Mol Cell. 2018 08 16; 71(4):567-580.e4. PMID: 30118679.
    Citations: 32     Fields:    Translation:AnimalsCells
  9. Zurita Rendón O, Fredrickson EK, Howard CJ, Van Vranken J, Fogarty S, Tolley ND, Kalia R, Osuna BA, Shen PS, Hill CP, Frost A, Rutter J. Vms1p is a release factor for the ribosome-associated quality control complex. Nat Commun. 2018 06 06; 9(1):2197. PMID: 29875445.
    Citations: 28     Fields:    Translation:AnimalsCells
  10. Cory SA, Van Vranken JG, Brignole EJ, Patra S, Winge DR, Drennan CL, Rutter J, Barondeau DP. Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):E5325-E5334. PMID: 28634302.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  11. Van Vranken JG, Rutter J. The Whole (Cell) Is Less Than the Sum of Its Parts. Cell. 2016 Aug 25; 166(5):1078-1079. PMID: 27565337.
    Citations: 4     Fields:    Translation:HumansCells
  12. Van Vranken JG, Jeong MY, Wei P, Chen YC, Gygi SP, Winge DR, Rutter J. The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis. Elife. 2016 08 19; 5. PMID: 27540631; PMCID: PMC4991935.
    Citations: 61     Fields:    Translation:AnimalsCells
  13. Van Vranken JG, Rutter J. You Down With ETC? Yeah, You Know D! Cell. 2015 Jul 30; 162(3):471-3. PMID: 26232217.
    Citations: 9     Fields:    
  14. Van Vranken JG, Na U, Winge DR, Rutter J. Protein-mediated assembly of succinate dehydrogenase and its cofactors. Crit Rev Biochem Mol Biol. 2015 Mar-Apr; 50(2):168-80. PMID: 25488574; PMCID: PMC4653115.
    Citations: 44     Fields:    Translation:HumansCells
  15. Schell JC, Olson KA, Jiang L, Hawkins AJ, Van Vranken JG, Xie J, Egnatchik RA, Earl EG, DeBerardinis RJ, Rutter J. A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth. Mol Cell. 2014 Nov 06; 56(3):400-413. PMID: 25458841.
    Citations: 155     Fields:    Translation:HumansAnimalsCells
  16. Van Vranken JG, Bricker DK, Dephoure N, Gygi SP, Cox JE, Thummel CS, Rutter J. SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration. Cell Metab. 2014 Aug 05; 20(2):241-52. PMID: 24954416.
    Citations: 44     Fields:    Translation:AnimalsCells
  17. Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J. A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science. 2012 Jul 06; 337(6090):96-100. PMID: 22628558.
    Citations: 344     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.