Harvard Catalyst Profiles

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Mark B. Jones, Ph.D.

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Biography
The Johns Hopkins University, Baltimore, MDB.S.2003Biomedical Engineering
The Johns Hopkins University, Baltimore, MDM.S.E.2006Biomedical Engineering
RPCI at SUNY Buffalo, Buffalo, NYPh.D.2012Molecular and Cellular Biology

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32AI114109 (JONES, MARK B) Jun 1, 2015 - Jun 30, 2017
    NIH/NIAID
    Connecting the microbiota to peripheral immune quiescence by T cell crosstalk
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jones MB, Alvarez CA, Johnson JL, Zhou JY, Morris N, Cobb BA. CD45Rb-low effector T cells require IL-4 to induce IL-10 in FoxP3 Tregs and to protect mice from inflammation. PLoS One. 2019; 14(5):e0216893. PMID: 31120919.
    Citations:    
  2. Johnson JL, Jones MB, Cobb BA. Polysaccharide-experienced effector T cells induce IL-10 in FoxP3+ regulatory T cells to prevent pulmonary inflammation. Glycobiology. 2018 12 01; 28(1):50-58. PMID: 29087497.
    Citations:    
  3. Cobb BA, Jones MB. Special Issue: The role of glycans in immunity and disease. Cell Immunol. 2018 Nov; 333:1. PMID: 30554675.
    Citations:    
  4. Oswald DM, Sim ES, Baker C, Farhan O, Debanne SM, Morris NJ, Rodriguez BG, Jones MB, Cobb BA. Plasma glycomics predict cardiovascular disease in patients with ART-controlled HIV infections. FASEB J. 2019 Feb; 33(2):1852-1859. PMID: 30183373.
    Citations:    
  5. Jones MB. IgG and leukocytes: Targets of immunomodulatory a2,6 sialic acids. Cell Immunol. 2018 Nov; 333:58-64. PMID: 29685495.
    Citations:    
  6. Jun JC, Jones MB, Oswald DM, Sim ES, Jonnalagadda AR, Kreisman LSC, Cobb BA. T cell-intrinsic TLR2 stimulation promotes IL-10 expression and suppressive activity by CD45RbHi T cells. PLoS One. 2017; 12(7):e0180688. PMID: 28742882.
    Citations:    
  7. Jones MB, Oswald DM, Joshi S, Whiteheart SW, Orlando R, Cobb BA. B-cell-independent sialylation of IgG. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7207-12. PMID: 27303031.
    Citations:    
  8. Jones MB, Ryan SO, Johnson JL, Cobb BA. Dendritic cell-specific Mgat2 knockout mice show antigen presentation defects but reveal an unexpected CD11c expression pattern. Glycobiology. 2016 09; 26(9):1007-1013. PMID: 27146521.
    Citations:    
  9. Johnson JL, Jones MB, Cobb BA. Polysaccharide A from the capsule of Bacteroides fragilis induces clonal CD4+ T cell expansion. J Biol Chem. 2015 Feb 20; 290(8):5007-14. PMID: 25540199.
    Citations:    
  10. Johnson JL, Jones MB, Cobb BA. Bacterial capsular polysaccharide prevents the onset of asthma through T-cell activation. Glycobiology. 2015 Apr; 25(4):368-75. PMID: 25347992.
    Citations:    
  11. Jun JC, Kertesy S, Jones MB, Marinis JM, Cobb BA, Tigno-Aranjuez JT, Abbott DW. Innate immune-directed NF-?B signaling requires site-specific NEMO ubiquitination. Cell Rep. 2013 Jul 25; 4(2):352-61. PMID: 23871670.
    Citations:    
  12. Johnson JL, Jones MB, Ryan SO, Cobb BA. The regulatory power of glycans and their binding partners in immunity. Trends Immunol. 2013 Jun; 34(6):290-8. PMID: 23485517.
    Citations:    
  13. Jones MB, Nasirikenari M, Lugade AA, Thanavala Y, Lau JT. Anti-inflammatory IgG production requires functional P1 promoter in ß-galactoside a2,6-sialyltransferase 1 (ST6Gal-1) gene. J Biol Chem. 2012 May 04; 287(19):15365-70. PMID: 22427662.
    Citations:    
  14. Jones MB, Nasirikenari M, Feng L, Migliore MT, Choi KS, Kazim L, Lau JT. Role for hepatic and circulatory ST6Gal-1 sialyltransferase in regulating myelopoiesis. J Biol Chem. 2010 Aug 06; 285(32):25009-17. PMID: 20529847.
    Citations:    
  15. Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconj J. 2010 May; 27(4):445-59. PMID: 20458533.
    Citations: 4     Fields:    
  16. Sampathkumar SG, Jones MB, Meledeo MA, Campbell CT, Choi SS, Hida K, Gomutputra P, Sheh A, Gilmartin T, Head SR, Yarema KJ. Targeting glycosylation pathways and the cell cycle: sugar-dependent activity of butyrate-carbohydrate cancer prodrugs. Chem Biol. 2006 Dec; 13(12):1265-75. PMID: 17185222.
    Citations:    
  17. Sampathkumar SG, Li AV, Jones MB, Sun Z, Yarema KJ. Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology. Nat Chem Biol. 2006 Mar; 2(3):149-52. PMID: 16474386.
    Citations:    
  18. Sampathkumar SG, Jones MB, Yarema KJ. Metabolic expression of thiol-derivatized sialic acids on the cell surface and their quantitative estimation by flow cytometry. Nat Protoc. 2006; 1(4):1840-51. PMID: 17487167.
    Citations:    
  19. Kim EJ, Jones MB, Rhee JK, Sampathkumar SG, Yarema KJ. Establishment of N-acetylmannosamine (ManNAc) analogue-resistant cell lines as improved hosts for sialic acid engineering applications. Biotechnol Prog. 2004 Nov-Dec; 20(6):1674-82. PMID: 15575698.
    Citations:    
  20. Jones MB, Teng H, Rhee JK, Lahar N, Baskaran G, Yarema KJ. Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids. Biotechnol Bioeng. 2004 Feb 20; 85(4):394-405. PMID: 14755557.
    Citations:    
  21. Kim EJ, Sampathkumar SG, Jones MB, Rhee JK, Baskaran G, Goon S, Yarema KJ. Characterization of the metabolic flux and apoptotic effects of O-hydroxyl- and N-acyl-modified N-acetylmannosamine analogs in Jurkat cells. J Biol Chem. 2004 Apr 30; 279(18):18342-52. PMID: 14966124.
    Citations:    
  22. Tong L, Baskaran G, Jones MB, Rhee JK, Yarema KJ. Glycosylation changes as markers for the diagnosis and treatment of human disease. Biotechnol Genet Eng Rev. 2003; 20:199-244. PMID: 14997853.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.