Harvard Catalyst Profiles

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Kazutaka Hayashida, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hibino S, Hayashida K. Modifiable Host Factors for the Prevention and Treatment of COVID-19: Diet and Lifestyle/Diet and Lifestyle Factors in the Prevention of COVID-19. Nutrients. 2022 Apr 29; 14(9). PMID: 35565841; PMCID: PMC9102954.
    Citations: 1     Fields:    Translation:HumansAnimalsPHPublic Health
  2. Hayashida K, Aquino RS, Park PW. Coreceptor functions of cell surface heparan sulfate proteoglycans. Am J Physiol Cell Physiol. 2022 05 01; 322(5):C896-C912. PMID: 35319900; PMCID: PMC9109798.
    Citations: 2     Fields:    Translation:Cells
  3. Aquino RS, Hayashida K, Hayashida A, Park PW. Role of HSPGs in Systemic Bacterial Infections. Methods Mol Biol. 2022; 2303:605-625. PMID: 34626410; PMCID: PMC8560348.
    Citations:    Fields:    Translation:AnimalsCells
  4. Nam EJ, Hayashida K, Aquino RS, Couchman JR, Kozar RA, Liu J, Park PW. Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice. Hepatology. 2017 11; 66(5):1601-1615. PMID: 28543100; PMCID: PMC6516470.
    Citations: 15     Fields:    Translation:AnimalsCells
  5. Volpi S, Yamazaki Y, Brauer PM, van Rooijen E, Hayashida A, Slavotinek A, Sun Kuehn H, Di Rocco M, Rivolta C, Bortolomai I, Du L, Felgentreff K, Ott de Bruin L, Hayashida K, Freedman G, Marcovecchio GE, Capuder K, Rath P, Luche N, Hagedorn EJ, Buoncompagni A, Royer-Bertrand B, Giliani S, Poliani PL, Imberti L, Dobbs K, Poulain FE, Martini A, Manis J, Linhardt RJ, Bosticardo M, Rosenzweig SD, Lee H, Puck JM, Zúñiga-Pflücker JC, Zon L, Park PW, Superti-Furga A, Notarangelo LD. EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. J Exp Med. 2017 03 06; 214(3):623-637. PMID: 28148688; PMCID: PMC5339678.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  6. Kume N, Mitsuoka H, Hayashida K, Tanaka M. Pentraxin 3 as a biomarker for acute coronary syndrome: comparison with biomarkers for cardiac damage. J Cardiol. 2011 Jul; 58(1):38-45. PMID: 21616640.
    Citations: 17     Fields:    Translation:Humans
  7. Hayashida K, Bartlett AH, Chen Y, Park PW. Molecular and cellular mechanisms of ectodomain shedding. Anat Rec (Hoboken). 2010 Jun; 293(6):925-37. PMID: 20503387.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  8. Kume N, Mitsuoka H, Hayashida K, Tanaka M, Kominami G, Kita T. Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome--comparison with other biomarkers. J Cardiol. 2010 Sep; 56(2):159-65. PMID: 20605699.
    Citations: 26     Fields:    Translation:Humans
  9. Kume N, Mitsuoka H, Hayashida K, Tanaka M, Kita T. Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts prognosis after acute coronary syndrome--a pilot study. Circ J. 2010 Jul; 74(7):1399-404. PMID: 20467154.
    Citations: 24     Fields:    Translation:Humans
  10. Mitsuoka H, Toyohara M, Kume N, Hayashida K, Jinnai T, Tanaka M, Kita T. Circulating soluble SR-PSOX/CXCL16 as a biomarker for acute coronary syndrome -comparison with high-sensitivity C-reactive protein. J Atheroscler Thromb. 2009 Oct; 16(5):586-93. PMID: 19729872.
    Citations: 6     Fields:    Translation:Humans
  11. Hayashida K, Parks WC, Park PW. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines. Blood. 2009 Oct 01; 114(14):3033-43. PMID: 19638625; PMCID: PMC2756208.
    Citations: 83     Fields:    Translation:AnimalsCells
  12. Nakamura M, Ohta H, Kume N, Hayashida K, Tanaka M, Mitsuoka H, Kaneshige T, Misaki S, Imagawa K, Shimosako K, Ogawa N, Kita T, Kominami G. Generation of monoclonal antibodies against a soluble form of lectin-like oxidized low-density lipoprotein receptor-1 and development of a sensitive chemiluminescent enzyme immunoassay. J Pharm Biomed Anal. 2010 Jan 05; 51(1):158-63. PMID: 19632802.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  13. Hayashida K, Stahl PD, Park PW. Syndecan-1 ectodomain shedding is regulated by the small GTPase Rab5. J Biol Chem. 2008 Dec 19; 283(51):35435-44. PMID: 18957427.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  14. Hayashida K, Chen Y, Bartlett AH, Park PW. Syndecan-1 is an in vivo suppressor of Gram-positive toxic shock. J Biol Chem. 2008 Jul 18; 283(29):19895-903. PMID: 18499671.
    Citations: 22     Fields:    Translation:AnimalsCells
  15. Mitsuoka H, Kume N, Hayashida K, Inui-Hayashiada A, Aramaki Y, Toyohara M, Jinnai T, Nishi E, Kita T. Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1). Atherosclerosis. 2009 Jan; 202(1):176-82. PMID: 18514661.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  16. Bartlett AH, Hayashida K, Park PW. Molecular and cellular mechanisms of syndecans in tissue injury and inflammation. Mol Cells. 2007 Oct 31; 24(2):153-66. PMID: 17978567.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  17. Shibata Y, Kume N, Arai H, Hayashida K, Inui-Hayashida A, Minami M, Mukai E, Toyohara M, Harauma A, Murayama T, Kita T, Hara S, Kamei K, Yokode M. Mulberry leaf aqueous fractions inhibit TNF-alpha-induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 (LOX-1) expression in vascular endothelial cells. Atherosclerosis. 2007 Jul; 193(1):20-7. PMID: 17055514.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  18. Hayashida K, Johnston DR, Goldberger O, Park PW. Syndecan-1 expression in epithelial cells is induced by transforming growth factor beta through a PKA-dependent pathway. J Biol Chem. 2006 Aug 25; 281(34):24365-74. PMID: 16807246.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  19. Ueda A, Kume N, Hayashida K, Inui-Hayashida A, Asai M, Kita T, Kominami G. ELISA for soluble form of lectin-like oxidized LDL receptor-1, a novel marker of acute coronary syndrome. Clin Chem. 2006 Jun; 52(6):1210-1. PMID: 16723692.
    Citations: 6     Fields:    Translation:Humans
  20. Hayashida K, Kume N, Murase T, Minami M, Nakagawa D, Inada T, Tanaka M, Ueda A, Kominami G, Kambara H, Kimura T, Kita T. Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: a novel marker for early diagnosis. Circulation. 2005 Aug 09; 112(6):812-8. PMID: 16061745.
    Citations: 88     Fields:    Translation:Humans
  21. Hayashida K, Kume N, Minami M, Inui-Hayashida A, Mukai E, Toyohara M, Kita T. Peroxisome proliferator-activated receptor alpha ligands activate transcription of lectin-like oxidized low density lipoprotein receptor-1 gene through GC box motif. Biochem Biophys Res Commun. 2004 Oct 22; 323(3):1116-23. PMID: 15381115.
    Citations: 1     Fields:    Translation:AnimalsCells
  22. Mukai E, Kume N, Hayashida K, Minami M, Yamada Y, Seino Y, Kita T. Heparin-binding EGF-like growth factor induces expression of lectin-like oxidized LDL receptor-1 in vascular smooth muscle cells. Atherosclerosis. 2004 Oct; 176(2):289-96. PMID: 15380451.
    Citations: 8     Fields:    Translation:AnimalsCells
  23. Shimaoka T, Nakayama T, Hieshima K, Kume N, Fukumoto N, Minami M, Hayashida K, Kita T, Yoshie O, Yonehara S. Chemokines generally exhibit scavenger receptor activity through their receptor-binding domain. J Biol Chem. 2004 Jun 25; 279(26):26807-10. PMID: 15128749.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  24. Shimaoka T, Nakayama T, Fukumoto N, Kume N, Takahashi S, Yamaguchi J, Minami M, Hayashida K, Kita T, Ohsumi J, Yoshie O, Yonehara S. Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells. J Leukoc Biol. 2004 Feb; 75(2):267-74. PMID: 14634054.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  25. Shimaoka T, Nakayama T, Kume N, Takahashi S, Yamaguchi J, Minami M, Hayashida K, Kita T, Ohsumi J, Yoshie O, Yonehara S. Cutting edge: SR-PSOX/CXC chemokine ligand 16 mediates bacterial phagocytosis by APCs through its chemokine domain. J Immunol. 2003 Aug 15; 171(4):1647-51. PMID: 12902461.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  26. Hayashida K, Tanaka M, Morita H, Hayashi F, Inada T, Suzuki H, Sakamoto T, Katsuragawa M, Hibino H, Kambara H. Chlamydia pneumoniae seropositivity predicts the risk of restenosis after percutaneous transluminal coronary angioplasty. Heart Vessels. 2002 May; 16(4):137-45. PMID: 12224784.
    Citations: 2     Fields:    Translation:HumansCells
  27. Hayashida K, Kume N, Minami M, Kita T. Lectin-like oxidized LDL receptor-1 (LOX-1) supports adhesion of mononuclear leukocytes and a monocyte-like cell line THP-1 cells under static and flow conditions. FEBS Lett. 2002 Jan 30; 511(1-3):133-8. PMID: 11821063.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.