Harvard Catalyst Profiles

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Ahmed Elzoghby, Ph.D.

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Biography
education and training
Brigham and Women's HospitalPostdoc Fellow07/2022Biomedical Engineering (Immunoengineering)
Cancer Nanotechnology Research Laboratory (CNRL) Director12/2017Pharmaceutical Sciences (Drug Delivery)
Faculty of Pharmacy, Alexandria University Ph.D.10/2012Pharmaceutical Sciences (Drug Delivery)
Faculty of Pharmacy, Alexandria UniversityM.Sc.09/2009Pharmaceutical Sciences (Drug Delivery)
Faculty of Pharmacy, Alexandria UniversityB.Sc.06/2003Pharmaceutical Sciences
awards and honors
2018
Fulbright Visiting Scholar Award
2021
Highly Cited Researcher Award
2022
Highly Cited Researcher Award
2022
BRIght Futures Prize Award
2023
Highly Cited Researcher Award
2024
Litwin IBD Pioneers Award
2024
Department of Defense Concept Award
2024
Joslin DRC Pilot & Feasibility Award
2025
Department of Defense Discovery Award

Overview
overview
My research focuses on immunoengineering of tumor microenvironment (TME) to overcome the resistance to cancer immunotherapy. More particularly, I am engineering innovative nanomedicines to disrupt the vicious crosstalk between cancer cells and stromal cancer associated fibroblasts (CAFs) via modulating the release and cargo of tumoral and stromal exosomes.
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. PR240001 (Ahmed Elzoghby) Jan 1, 2025 - Dec 31, 2026
    Department of Defense office of the Congressionally Directed Medical Research Programs (CDMRP)
    Highly Penetrating Nanodisc for Targeting Fibroblast Plasticity in Pulmonary Fibrosis
    Role: Principal Investigator
  2. 2023A072971 (Ahmed Elzoghby) May 1, 2024
    Joslin DRC Pilot & Feasibility Program, Joslin Diabetes Center
    Halting Diabetic Renal Fibrosis Progression using Bimodal Circularized Nanodisc
    Role: Principal Investigator
  3. 1158589 (Ahmed Elzoghby) Jan 1, 2024 - Dec 31, 2024
    Litwin IBD Pioneers Program, Crohn's & Colitis Foundation
    Engineered nanomedicine for reversal of fibrosis in Crohn's disease patients
    Role: Principal Investigator
  4. KC230061 (Ahmed Elzoghby) Jan 1, 2024 - Dec 31, 2024
    Department of Defense office of the Congressionally Directed Medical Research Programs (CDMRP)
    Engineering AntagomiR Nanodiscs to Reprogram Renal Cell Carcinoma-Associated Fibroblasts
    Role: Principal Investigator
  5. 2022A015398 (Ahmed Elzoghby) Nov 1, 2022 - Oct 31, 2024
    BRIght Futures Prize 2022, Brigham Research Institute (BRI)
    Genetically Engineered Fibroblasts as In Situ Factory of Cytolytic Exosomes
    Role: Principal Investigator

Bibliographic
selected publications
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.