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Chenxi Qiu, Ph.D.

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Biography
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Texas A&M University, College StationPh.D.12/2017Biochemistry

Research
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. 1K99AG076739 (Chenxi Qiu) Sep 1, 2022 - Aug 31, 2024
    NIH/NIA
    Cis proline directed proteotoxicity in the early development and therapy oftraumatic brain injury and vascular dementia
    Role: Principal Investigator
  2. AARF-19-617868 (Chenxi Qiu) Apr 1, 2019 - Aug 31, 2022
    Alzheimer's Association
    Cis phosphorylated tau in the development and therapy of vascular dementia
    Role Description: The major goal of this fellowship is to investigate the pathogenic role of cis P-tau and the therapeutic potential of cis P-tau monoclonal antibody in vascular dementia.
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tomita Y, Qiu C, Bull E, Allen W, Kotoda Y, Talukdar S, Smith LEH, Fu Z. Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa. Exp Mol Med. 2021 11; 53(11):1748-1758. PMID: 34799683; PMCID: PMC8639781.
    Citations: 2     Fields:    Translation:AnimalsCells
  2. Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz TD, Pinch BJ, Akshinthala D, Verma A, Gaglia G, Nezu Y, Ke S, Qiu C, Ohuchida K, Oda Y, Lee TH, Wegiel B, Clohessy JG, London N, Santagata S, Wulf GM, Hidalgo M, Muthuswamy SK, Nakamura M, Gray NS, Zhou XZ, Lu KP. Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy. Cell. 2021 09 02; 184(18):4753-4771.e27. PMID: 34388391; PMCID: PMC8557351.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  3. Qiu C, Albayram O, Kondo A, Wang B, Kim N, Arai K, Tsai CY, Bassal MA, Herbert MK, Washida K, Angeli P, Kozono S, Stucky JE, Baxley S, Lin YM, Sun Y, Rotenberg A, Caldarone BJ, Bigio EH, Chen X, Tenen DG, Zeidel M, Lo EH, Zhou XZ, Lu KP. Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice. Sci Transl Med. 2021 06 02; 13(596). PMID: 34078745; PMCID: PMC8272885.
    Citations: 3     Fields:    Translation:HumansAnimals
  4. Kim N, Wang B, Koikawa K, Nezu Y, Qiu C, Lee TH, Zhou XZ. Inhibition of death-associated protein kinase 1 attenuates cis P-tau and neurodegeneration in traumatic brain injury. Prog Neurobiol. 2021 08; 203:102072. PMID: 33979671; PMCID: PMC8217320.
    Citations: 6     Fields:    Translation:AnimalsCells
  5. Fu Z, Qiu C, Cagnone G, Tomita Y, Huang S, Cakir B, Kotoda Y, Allen W, Bull E, Akula JD, Joyal JS, Hellström A, Talukdar S, Smith LEH. Retinal glial remodeling by FGF21 preserves retinal function during photoreceptor degeneration. iScience. 2021 Apr 23; 24(4):102376. PMID: 33937726.
    Citations: 4     
  6. Qiu C, Jin H, Vvedenskaya I, Llenas JA, Zhao T, Malik I, Visbisky AM, Schwartz SL, Cui P, Cabart P, Han KH, Lai WKM, Metz RP, Johnson CD, Sze SH, Pugh BF, Nickels BE, Kaplan CD. Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae. Genome Biol. 2020 06 02; 21(1):132. PMID: 32487207.
    Citations: 14     Fields:    Translation:AnimalsCells
  7. Albayram O, MacIver B, Mathai J, Verstegen A, Baxley S, Qiu C, Bell C, Caldarone BJ, Zhou XZ, Lu KP, Zeidel M. Traumatic Brain Injury-related voiding dysfunction in mice is caused by damage to rostral pathways, altering inputs to the reflex pathways. Sci Rep. 2019 06 14; 9(1):8646. PMID: 31201348.
    Citations: 4     Fields:    Translation:Animals
  8. Qiu C, Kaplan CD. Functional assays for transcription mechanisms in high-throughput. Methods. 2019 04 15; 159-160:115-123. PMID: 30797033.
    Citations: 3     Fields:    Translation:AnimalsCells
  9. Kozono S, Lin YM, Seo HS, Pinch B, Lian X, Qiu C, Herbert MK, Chen CH, Tan L, Gao ZJ, Massefski W, Doctor ZM, Jackson BP, Chen Y, Dhe-Paganon S, Lu KP, Zhou XZ. Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nat Commun. 2018 08 09; 9(1):3069. PMID: 30093655.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  10. Lian X, Lin YM, Kozono S, Herbert MK, Li X, Yuan X, Guo J, Guo Y, Tang M, Lin J, Huang Y, Wang B, Qiu C, Tsai CY, Xie J, Gao ZJ, Wu Y, Liu H, Zhou XZ, Lu KP, Chen Y. Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways. J Hematol Oncol. 2018 05 30; 11(1):73. PMID: 29848341.
    Citations: 11     Fields:    Translation:HumansAnimals
  11. Malik I, Qiu C, Snavely T, Kaplan CD. Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo. Nucleic Acids Res. 2017 05 05; 45(8):4431-4451. PMID: 28119420; PMCID: PMC5416818.
    Citations: 19     Fields:    Translation:AnimalsCells
  12. Qiu C, Erinne OC, Dave JM, Cui P, Jin H, Muthukrishnan N, Tang LK, Babu SG, Lam KC, Vandeventer PJ, Strohner R, Van den Brulle J, Sze SH, Kaplan CD. High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop. PLoS Genet. 2016 Nov; 12(11):e1006321. PMID: 27898685.
    Citations: 17     Fields:    Translation:AnimalsCells
  13. Wang H, Qiao Y, Chai B, Qiu C, Chen X. Identification and molecular characterization of the homogentisate pathway responsible for pyomelanin production, the major melanin constituents in Aeromonas media WS. PLoS One. 2015; 10(3):e0120923. PMID: 25793756.
    Citations: 20     Fields:    Translation:Cells
  14. Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, Kaplan CD, Krogan NJ. From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II. Cell. 2013 Aug 15; 154(4):775-88. PMID: 23932120.
    Citations: 81     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.