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Sian Victoria Owen, Ph.D.

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Overview
Siân Owen completed her PhD and a short postdoctoral fellowship at the University of Liverpool, UK, in the group of Professor Jay Hinton. Sian's research explored the biological contribution of temperate bacteriophages to an emerging variant of Salmonella enterica serovar Typhimurium that is associated with an epidemic of bloodstream infections in sub-Saharan Africa. She is currently working in the Baym Lab in the Department of Biomedical Informatics and the Laboratory of Systems Pharmacology using experimental evolution and computational approaches to study the phenomenon of antibiotic resistance in bacteria.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hammarlöf DL, Kröger C, Owen SV, Canals R, Lacharme-Lora L, Wenner N, Schager AE, Wells TJ, Henderson IR, Wigley P, Hokamp K, Feasey NA, Gordon MA, Hinton JCD. Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):E2614-E2623. PMID: 29487214.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  2. Ashton PM, Owen SV, Kaindama L, Rowe WPM, Lane CR, Larkin L, Nair S, Jenkins C, de Pinna EM, Feasey NA, Hinton JCD, Dallman TJ. Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa. Genome Med. 2017 10 31; 9(1):92. PMID: 29084588.
    Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  3. Faulkner M, Rodriguez-Ramos J, Dykes GF, Owen SV, Casella S, Simpson DM, Beynon RJ, Liu LN. Direct characterization of the native structure and mechanics of cyanobacterial carboxysomes. Nanoscale. 2017 Aug 03; 9(30):10662-10673. PMID: 28616951.
    Citations: 3     Fields:    Translation:Cells
  4. Owen SV, Wenner N, Canals R, Makumi A, Hammarlöf DL, Gordon MA, Aertsen A, Feasey NA, Hinton JC. Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1. Front Microbiol. 2017; 8:235. PMID: 28280485.
    Citations: 6     
  5. Connor TR, Owen SV, Langridge G, Connell S, Nair S, Reuter S, Dallman TJ, Corander J, Tabing KC, Le Hello S, Fookes M, Doublet B, Zhou Z, Feltwell T, Ellington MJ, Herrera S, Gilmour M, Cloeckaert A, Achtman M, Parkhill J, Wain J, De Pinna E, Weill FX, Peters T, Thomson N. What's in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B. MBio. 2016 08 23; 7(4). PMID: 27555304.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  6. Srikumar S, Kröger C, Hébrard M, Colgan A, Owen SV, Sivasankaran SK, Cameron AD, Hokamp K, Hinton JC. RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium. PLoS Pathog. 2015; 11(11):e1005262. PMID: 26561851.
    Citations: 26     Fields:    Translation:Cells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.