Harvard Catalyst Profiles

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Takaharu Ichimura, Ph.D.

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  1. R01DK046267 (ICHIMURA, TAKAHARU) Jan 1, 1994 - Dec 31, 2006
    NIH
    BIOCHEMICAL TOXICOLOGY AND MOLECULAR STRESS RESPONSES
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Dai L, Uehara M, Li X, LaBarre BA, Banouni N, Ichimura T, Lee-Sundlov MM, Kasinath V, Sullivan JA, Ni H, Barone F, Giannini S, Bahmani B, Sage PT, Patsopoulos NA, Tsokos GC, Bromberg JS, Hoffmeister K, Jiang L, Abdi R. Characterization of CD41+ cells in the lymph node. Front Immunol. 2022; 13:801945. PMID: 36032128; PMCID: PMC9405417.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Sugisaki T, Aoyama T, Kawakami K, Yokokawa T, Kobayashi K, Suzuki W, Ogura M, Ichimura T, Chin K, Yamaguchi K, Hanaoka S, Hayashi H, Yamaguchi M. Correlation between magnesium pre-loading and cisplatin-induced nephrotoxicity in 5-fluorouracil/cisplatin combination therapy for esophageal cancer. Pharmazie. 2022 02 01; 77(2):85-88. PMID: 35209969.
    Citations:    Fields:    Translation:Humans
  3. Mori Y, Fink C, Ichimura T, Sako K, Mori M, Lee NN, Aschauer P, Padmanabha Das KM, Hong S, Song M, Padera RF, Weins A, Lee LP, Nasr ML, Dekaban GA, Dikeakos JD, Bonventre JV. KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney. medRxiv. 2022 Jan 11. PMID: 32995803; PMCID: PMC7523142.
    Citations:    
  4. Mychaleckyj JC, Valo E, Ichimura T, Ahluwalia TS, Dina C, Miller RG, Shabalin IG, Gyorgy B, Cao J, Onengut-Gumuscu S, Satake E, Smiles AM, Haukka JK, Tregouet DA, Costacou T, O'Neil K, Paterson AD, Forsblom C, Keenan HA, Pezzolesi MG, Pragnell M, Galecki A, Rich SS, Sandholm N, Klein R, Klein BE, Susztak K, Orchard TJ, Korstanje R, King GL, Hadjadj S, Rossing P, Bonventre JV, Groop PH, Warram JH, Krolewski AS. Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes. J Am Soc Nephrol. 2021 10; 32(10):2634-2651. PMID: 34261756; PMCID: PMC8722802.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  5. Zhao J, Jiang L, Uehara M, Banouni N, Al Dulaijan BS, Azzi J, Ichimura T, Li X, Jarolim P, Fiorina P, Tullius SG, Madsen JC, Kasinath V, Abdi R. ACTH treatment promotes murine cardiac allograft acceptance. JCI Insight. 2021 07 08; 6(13). PMID: 34236047; PMCID: PMC8410061.
    Citations: 3     Fields:    Translation:AnimalsCells
  6. Wiraja C, Mori Y, Ichimura T, Hwang J, Xu C, Bonventre JV. Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA Nanoflares. Nano Lett. 2021 07 14; 21(13):5850-5858. PMID: 34156251; PMCID: PMC9844158.
    Citations: 6     Fields:    Translation:Humans
  7. Li L, Galichon P, Xiao X, Figueroa-Ramirez AC, Tamayo D, Lee JJ, Kalocsay M, Gonzalez-Sanchez D, Chancay MS, McCracken KW, Lee NN, Ichimura T, Mori Y, Valerius MT, Wilflingseder J, Lemos DR, Edelman ER, Bonventre JV. Orphan nuclear receptor COUP-TFII enhances myofibroblast glycolysis leading to kidney fibrosis. EMBO Rep. 2021 06 04; 22(6):e51169. PMID: 34031962; PMCID: PMC8183413.
    Citations: 5     Fields:    Translation:AnimalsCells
  8. Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV. KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease. Cell Metab. 2021 05 04; 33(5):1042-1061.e7. PMID: 33951465; PMCID: PMC8132466.
    Citations: 37     Fields:    Translation:HumansAnimals
  9. Kishi S, Matsumoto T, Ichimura T, Brooks CR. Human reconstructed kidney models. In Vitro Cell Dev Biol Anim. 2021 Feb; 57(2):133-147. PMID: 33594607.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  10. Jiang L, Jung S, Zhao J, Kasinath V, Ichimura T, Joseph J, Fiorina P, Liss AS, Shah K, Annabi N, Joshi N, Akama TO, Bromberg JS, Kobayashi M, Uchimura K, Abdi R. Simultaneous targeting of primary tumor, draining lymph node, and distant metastases through high endothelial venule-targeted delivery. Nano Today. 2021 Feb; 36. PMID: 33391389; PMCID: PMC7774643.
    Citations: 10     
  11. Jiang L, Wang YJ, Zhao J, Uehara M, Hou Q, Kasinath V, Ichimura T, Banouni N, Dai L, Li X, Greiner DL, Shultz LD, Zhang X, Sun ZJ, Curtin I, Vangos NE, Yeoh ZC, Geffken EA, Seo HS, Liu ZX, Heffron GJ, Shah K, Dhe-Paganon S, Abdi R. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020 11 25; 183(5):1219-1233.e18. PMID: 33242418.
    Citations: 16     Fields:    Translation:AnimalsCells
  12. Ordikhani F, Kasinath V, Uehara M, Akbarzadeh A, Yilmam OA, Dai L, Aksu H, Jung S, Jiang L, Li X, Zhao J, Bahmani B, Ichimura T, Fiorina P, Annabi N, Abdi R. Selective Trafficking of Light Chain-Conjugated Nanoparticles to the Kidney and Renal Cell Carcinoma. Nano Today. 2020 Dec; 35. PMID: 33244320.
    Citations: 6     
  13. Cai S, Choi JY, Borges TJ, Zhang H, Miao J, Ichimura T, Li X, Xu S, Chu P, Eskandari SK, Allos H, Alhaddad JB, Muhsin SA, Yatim K, Riella LV, Sage PT, Chandraker AK, Azzi JR. Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo. Sci Rep. 2020 08 28; 10(1):14249. PMID: 32859934; PMCID: PMC7455707.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  14. Li X, Zhao J, Kasinath V, Uehara M, Jiang L, Banouni N, McGrath MM, Ichimura T, Fiorina P, Lemos DR, Shin SR, Ware CF, Bromberg JS, Abdi R. Lymph node fibroblastic reticular cells deposit fibrosis-associated collagen following organ transplantation. J Clin Invest. 2020 08 03; 130(8):4182-4194. PMID: 32597832; PMCID: PMC7410068.
    Citations: 12     Fields:    Translation:AnimalsCells
  15. Wilflingseder J, Willi M, Lee HK, Olauson H, Jankowski J, Ichimura T, Erben R, Valerius MT, Hennighausen L, Bonventre JV. Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury. Nat Commun. 2020 07 07; 11(1):3383. PMID: 32636391; PMCID: PMC7341735.
    Citations: 18     Fields:    Translation:AnimalsCells
  16. Kishi S, Brooks CR, Taguchi K, Ichimura T, Mori Y, Akinfolarin A, Gupta N, Galichon P, Elias BC, Suzuki T, Wang Q, Gewin L, Morizane R, Bonventre JV. Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses. J Clin Invest. 2019 11 01; 129(11):4797-4816. PMID: 31589169; PMCID: PMC6819104.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  17. Goldman A, Khiste S, Freinkman E, Dhawan A, Majumder B, Mondal J, Pinkerton AB, Eton E, Medhi R, Chandrasekar V, Rahman MM, Ichimura T, Gopinath KS, Majumder P, Kohandel M, Sengupta S. Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance. Sci Signal. 2019 08 20; 12(595). PMID: 31431543.
    Citations: 26     Fields:    Translation:HumansCells
  18. Kasinath V, Yilmam OA, Uehara M, Yonar M, Jiang L, Li X, Qiu W, Eskandari S, Ichimura T, Abdi R. Urine podoplanin heralds the onset of ischemia-reperfusion injury of the kidney. Am J Physiol Renal Physiol. 2019 05 01; 316(5):F957-F965. PMID: 30864839; PMCID: PMC6580248.
    Citations: 2     Fields:    Translation:AnimalsCells
  19. Canaud G, Brooks CR, Kishi S, Taguchi K, Nishimura K, Magassa S, Scott A, Hsiao LL, Ichimura T, Terzi F, Yang L, Bonventre JV. Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair. Sci Transl Med. 2019 01 23; 11(476). PMID: 30674655; PMCID: PMC6527117.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  20. Bahmani B, Uehara M, Ordikhani F, Li X, Jiang L, Banouni N, Ichimura T, Kasinath V, Eskandari SK, Annabi N, Bromberg JS, Shultz LD, Greiner DL, Abdi R. Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery. EBioMedicine. 2018 Dec; 38:79-88. PMID: 30497977; PMCID: PMC6306381.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  21. Bahmani B, Uehara M, Jiang L, Ordikhani F, Banouni N, Ichimura T, Solhjou Z, Furtmüller GJ, Brandacher G, Alvarez D, von Andrian UH, Uchimura K, Xu Q, Vohra I, Yilmam OA, Haik Y, Azzi J, Kasinath V, Bromberg JS, McGrath MM, Abdi R. Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival. J Clin Invest. 2018 11 01; 128(11):4770-4786. PMID: 30277476; PMCID: PMC6205374.
    Citations: 31     Fields:    Translation:AnimalsCells
  22. Uehara M, Solhjou Z, Banouni N, Kasinath V, Xiaqun Y, Dai L, Yilmam O, Yilmaz M, Ichimura T, Fiorina P, Martins PN, Ohori S, Guleria I, Maarouf OH, Tullius SG, McGrath MM, Abdi R. Ischemia augments alloimmune injury through IL-6-driven CD4+ alloreactivity. Sci Rep. 2018 02 06; 8(1):2461. PMID: 29410442.
    Citations: 21     Fields:    Translation:AnimalsCells
  23. Okamura A, Watanabe M, Mine S, Kurogochi T, Yamashita K, Hayami M, Imamura Y, Ogura M, Ichimura T, Takahari D, Chin K. Failure of neoadjuvant chemotherapy for resectable esophageal squamous cell carcinoma. Dis Esophagus. 2017 Sep 01; 30(9):1-8. PMID: 28859367.
    Citations: 7     Fields:    Translation:Humans
  24. Solhjou Z, Uehara M, Bahmani B, Maarouf OH, Ichimura T, Brooks CR, Xu W, Yilmaz M, Elkhal A, Tullius SG, Guleria I, McGrath MM, Abdi R. Novel Application of Localized Nanodelivery of Anti-Interleukin-6 Protects Organ Transplant From Ischemia-Reperfusion Injuries. Am J Transplant. 2017 Sep; 17(9):2326-2337. PMID: 28296000; PMCID: PMC5573642.
    Citations: 16     Fields:    Translation:AnimalsCells
  25. Zhou Y, Chen H, Liu L, Yu X, Sukhova GK, Yang M, Zhang L, Kyttaris VC, Tsokos GC, Stillman IE, Ichimura T, Bonventre JV, Libby P, Shi GP. CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice. J Immunol. 2017 04 01; 198(7):2568-2577. PMID: 28219888; PMCID: PMC5360510.
    Citations: 6     Fields:    Translation:AnimalsCells
  26. Fischer K, Ohori S, Meral FC, Uehara M, Giannini S, Ichimura T, Smith RN, Jolesz FA, Guleria I, Zhang Y, White PJ, McDannold NJ, Hoffmeister K, Givertz MM, Abdi R. Testing the Efficacy of Contrast-Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation. Am J Transplant. 2017 Jul; 17(7):1791-1801. PMID: 28009476; PMCID: PMC5481513.
    Citations: 6     Fields:    Translation:Animals
  27. Azzi J, Yin Q, Uehara M, Ohori S, Tang L, Cai K, Ichimura T, McGrath M, Maarouf O, Kefaloyianni E, Loughhead S, Petr J, Sun Q, Kwon M, Tullius S, von Andrian UH, Cheng J, Abdi R. Targeted Delivery of Immunomodulators to Lymph Nodes. Cell Rep. 2016 05 10; 15(6):1202-13. PMID: 27134176.
    Citations: 30     Fields:    Translation:Animals
  28. Fischer K, Meral FC, Zhang Y, Vangel MG, Jolesz FA, Ichimura T, Bonventre JV. High-resolution renal perfusion mapping using contrast-enhanced ultrasonography in ischemia-reperfusion injury monitors changes in renal microperfusion. Kidney Int. 2016 06; 89(6):1388-98. PMID: 27165821; PMCID: PMC4870008.
    Citations: 16     Fields:    Translation:HumansAnimals
  29. Suzuki T, Yamaguchi H, Kikusato M, Hashizume O, Nagatoishi S, Matsuo A, Sato T, Kudo T, Matsuhashi T, Murayama K, Ohba Y, Watanabe S, Kanno S, Minaki D, Saigusa D, Shinbo H, Mori N, Yuri A, Yokoro M, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Kikuchi K, Toyohara T, Suzuki C, Ichimura T, Anzai J, Kohzuki M, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Tsumoto K, Nakada K, Bonventre JV, Ito S, Osaka H, Hayashi K, Abe T. Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage. J Am Soc Nephrol. 2016 07; 27(7):1925-32. PMID: 26609120; PMCID: PMC4926982.
    Citations: 39     Fields:    Translation:AnimalsCells
  30. Shinke H, Masuda S, Togashi Y, Ikemi Y, Ozawa A, Sato T, Kim YH, Mishima M, Ichimura T, Bonventre JV, Matsubara K. Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients. Cancer Chemother Pharmacol. 2015 Nov; 76(5):989-96. PMID: 26407820.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  31. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV. KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. EMBO J. 2015 Oct 01; 34(19):2441-64. PMID: 26282792; PMCID: PMC4601664.
    Citations: 43     Fields:    Translation:HumansCells
  32. Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV. Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury. EBioMedicine. 2015 Sep; 2(9):1090-101. PMID: 26501107.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  33. Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV. KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest. 2015 Apr; 125(4):1620-36. PMID: 25751064; PMCID: PMC4396492.
    Citations: 140     Fields:    Translation:AnimalsCells
  34. Besschetnova TY, Ichimura T, Katebi N, St Croix B, Bonventre JV, Olsen BR. Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 2015 Mar; 42:56-73. PMID: 25572963; PMCID: PMC4409530.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  35. Mishima E, Inoue C, Saigusa D, Inoue R, Ito K, Suzuki Y, Jinno D, Tsukui Y, Akamatsu Y, Araki M, Araki K, Shimizu R, Shinke H, Suzuki T, Takeuchi Y, Shima H, Akiyama Y, Toyohara T, Suzuki C, Saiki Y, Tominaga T, Miyagi S, Kawagisihi N, Soga T, Ohkubo T, Yamamura K, Imai Y, Masuda S, Sabbisetti V, Ichimura T, Mount DB, Bonventre JV, Ito S, Tomioka Y, Itoh K, Abe T. Conformational change in transfer RNA is an early indicator of acute cellular damage. J Am Soc Nephrol. 2014 Oct; 25(10):2316-26. PMID: 24833129.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  36. Batal I, Azzi J, Mounayar M, Abdoli R, Moore R, Lee JY, Rosetti F, Wang C, Fiorina P, Sackstein R, Ichimura T, Abdi R. The mechanisms of up-regulation of dendritic cell activity by oxidative stress. J Leukoc Biol. 2014 Aug; 96(2):283-93. PMID: 24676276.
    Citations: 14     Fields:    Translation:AnimalsCells
  37. Bassi R, Vergani A, D'Addio F, Ben Nasr M, Mocci A, Rastaldi MP, Ichimura T, Bonventre JV, Fiorina P. Positive effects of a novel non-peptidyl low molecular weight radical scavenger in renal ischemia/reperfusion: a preliminary report. Springerplus. 2014; 3:158. PMID: 24741476.
    Citations: 4     
  38. Abu-Saleh N, Awad H, Khamaisi M, Armaly Z, Karram T, Heyman SN, Kaballa A, Ichimura T, Holman J, Abassi Z. Nephroprotective effects of TVP1022, a non-MAO inhibitor S-isomer of rasagiline, in an experimental model of diabetic renal ischemic injury. Am J Physiol Renal Physiol. 2014 Jan 01; 306(1):F24-33. PMID: 24197064.
    Citations: 6     Fields:    Translation:AnimalsCells
  39. Humphreys BD, Xu F, Sabbisetti V, Grgic I, Movahedi Naini S, Wang N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, Bonventre JV. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest. 2013 Sep; 123(9):4023-35. PMID: 23979159; PMCID: PMC3755983.
    Citations: 145     Fields:    Translation:AnimalsCells
  40. Timsit MO, Adams WJ, Laguna-Fernandez A, Ichimura T, Bonventre JV, García-Cardeña G, Tullius SG. Flow is critical for maintaining a protective phenotype in renal proximal tubular cells. Am J Transplant. 2013 Jun; 13(6):1617-8. PMID: 23617882; PMCID: PMC4625983.
    Citations: 3     Fields:    Translation:Humans
  41. Nishihara K, Masuda S, Shinke H, Ozawa A, Ichimura T, Yonezawa A, Nakagawa S, Inui K, Bonventre JV, Matsubara K. Urinary chemokine (C-C motif) ligand 2 (monocyte chemotactic protein-1) as a tubular injury marker for early detection of cisplatin-induced nephrotoxicity. Biochem Pharmacol. 2013 Feb 15; 85(4):570-82. PMID: 23291264.
    Citations: 17     Fields:    Translation:AnimalsCells
  42. Milwid JM, Ichimura T, Li M, Jiao Y, Lee J, Yarmush JS, Parekkadan B, Tilles AW, Bonventre JV, Yarmush ML. Secreted factors from bone marrow stromal cells upregulate IL-10 and reverse acute kidney injury. Stem Cells Int. 2012; 2012:392050. PMID: 23319959.
    Citations: 13     
  43. Havasi A, Haegele JA, Gall JM, Blackmon S, Ichimura T, Bonegio RG, Panchenko MV. Histone acetyl transferase (HAT) HBO1 and JADE1 in epithelial cell regeneration. Am J Pathol. 2013 Jan; 182(1):152-62. PMID: 23159946; PMCID: PMC3532714.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  44. Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12105-10. PMID: 22773818.
    Citations: 70     Fields:    Translation:AnimalsCells
  45. Ichimura T, Brooks CR, Bonventre JV. Kim-1/Tim-1 and immune cells: shifting sands. Kidney Int. 2012 May; 81(9):809-11. PMID: 22499138.
    Citations: 30     Fields:    Translation:AnimalsCells
  46. Grgic I, Campanholle G, Bijol V, Wang C, Sabbisetti VS, Ichimura T, Humphreys BD, Bonventre JV. Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis. Kidney Int. 2012 Jul; 82(2):172-83. PMID: 22437410.
    Citations: 210     Fields:    Translation:AnimalsCells
  47. Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV, Shen J. Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway. Mol Neurodegener. 2012 Jan 09; 7:2. PMID: 22230652; PMCID: PMC3296570.
    Citations: 108     Fields:    Translation:HumansAnimalsCells
  48. Qin Y, Alderliesten MC, Stokman G, Pennekamp P, Bonventre JV, de Heer E, Ichimura T, de Graauw M, Price LS, van de Water B. Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion. Am J Pathol. 2011 Dec; 179(6):2766-78. PMID: 21982831; PMCID: PMC3260828.
    Citations: 7     Fields:    Translation:AnimalsCells
  49. Azzi J, Tang L, Moore R, Tong R, El Haddad N, Akiyoshi T, Mfarrej B, Yang S, Jurewicz M, Ichimura T, Lindeman N, Cheng J, Abdi R. Polylactide-cyclosporin A nanoparticles for targeted immunosuppression. FASEB J. 2010 Oct; 24(10):3927-38. PMID: 20547662.
    Citations: 27     Fields:    Translation:Animals
  50. Jurewicz M, Takakura A, Augello A, Movahedi Naini S, Ichimura T, Zandi-Nejad K, Abdi R. Ischemic injury enhances dendritic cell immunogenicity via TLR4 and NF-kappa B activation. J Immunol. 2010 Mar 15; 184(6):2939-48. PMID: 20164431.
    Citations: 16     Fields:    Translation:AnimalsCells
  51. Nishihara K, Masuda S, Nakagawa S, Yonezawa A, Ichimura T, Bonventre JV, Inui K. Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats. Am J Physiol Renal Physiol. 2010 Apr; 298(4):F923-34. PMID: 20071461; PMCID: PMC4380486.
    Citations: 6     Fields:    Translation:AnimalsCells
  52. Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest. 2008 May; 118(5):1657-68. PMID: 18414680; PMCID: PMC2293335.
    Citations: 298     Fields:    Translation:HumansAnimalsCells
  53. Ichimura T, Mou S. Kidney injury molecule-1 in acute kidney injury and renal repair: a review. Zhong Xi Yi Jie He Xue Bao. 2008 May; 6(5):533-8. PMID: 18471422.
    Citations: 5     Fields:    Translation:HumansAnimals
  54. Rennert PD, Ichimura T, Sizing ID, Bailly V, Li Z, Rennard R, McCoon P, Pablo L, Miklasz S, Tarilonte L, Bonventre JV. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol. 2006 Oct 01; 177(7):4311-21. PMID: 16982865.
    Citations: 37     Fields:    Translation:AnimalsCells
  55. Tanaka Y, Kanai F, Ichimura T, Tateishi K, Asaoka Y, Guleng B, Jazag A, Ohta M, Imamura J, Ikenoue T, Ijichi H, Kawabe T, Isobe T, Omata M. The hepatitis B virus X protein enhances AP-1 activation through interaction with Jab1. Oncogene. 2006 Jan 26; 25(4):633-42. PMID: 16247477.
    Citations: 38     Fields:    Translation:HumansCells
  56. Vaidya VS, Ramirez V, Ichimura T, Bobadilla NA, Bonventre JV. Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol. 2006 Feb; 290(2):F517-29. PMID: 16174863.
    Citations: 233     Fields:    Translation:AnimalsCells
  57. Asmellash S, Stevens JL, Ichimura T. Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo. Toxicol Sci. 2005 Dec; 88(2):576-84. PMID: 16150886.
    Citations: 9     Fields:    Translation:AnimalsCells
  58. Schachter AD, Ichimura T, Kohane IS. Chromosomes 18 and X are quantitative trait loci for nephrotic-range proteinuria in rats. Pediatr Nephrol. 2005 Dec; 20(12):1717-23. PMID: 16133046; PMCID: PMC1343534.
    Citations: 1     Fields:    Translation:AnimalsCells
  59. Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, Bonventre JV. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest. 2005 Jul; 115(7):1743-55. PMID: 16007251; PMCID: PMC1159124.
    Citations: 211     Fields:    Translation:AnimalsCells
  60. Cho B, Ichimura T, Shimizu R, Oshima C. Quantitative evaluation of spatial coherence of the electron beam from low temperature field emitters. Phys Rev Lett. 2004 Jun 18; 92(24):246103. PMID: 15245108.
    Citations: 2     Fields:    
  61. Ichimura T, Hung CC, Yang SA, Stevens JL, Bonventre JV. Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol. 2004 Mar; 286(3):F552-63. PMID: 14600030.
    Citations: 224     Fields:    Translation:Animals
  62. Hung CC, Ichimura T, Stevens JL, Bonventre JV. Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem. 2003 Aug 01; 278(31):29317-26. PMID: 12738790.
    Citations: 68     Fields:    Translation:AnimalsCells
  63. Shimada M, Saito M, Katakai T, Shimizu A, Ichimura T, Omata S, Horigome T. Molecular cloning and splicing isoforms of mouse p144, a homologue of CA150. J Biochem. 1999 Dec; 126(6):1033-42. PMID: 10578054.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  64. Yamazoe M, Onogi T, Sunako Y, Niki H, Yamanaka K, Ichimura T, Hiraga S. Complex formation of MukB, MukE and MukF proteins involved in chromosome partitioning in Escherichia coli. EMBO J. 1999 Nov 01; 18(21):5873-84. PMID: 10545099; PMCID: PMC1171653.
    Citations: 55     Fields:    Translation:Cells
  65. Gohshi T, Shimada M, Kawahire S, Imai N, Ichimura T, Omata S, Horigome T. Molecular cloning of mouse p47, a second group mammalian RuvB DNA helicase-like protein: homology with those from human and Saccharomyces cerevisiae. J Biochem. 1999 May; 125(5):939-46. PMID: 10220587.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  66. Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, Sanicola M. Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem. 1998 Feb 13; 273(7):4135-42. PMID: 9461608.
    Citations: 448     Fields:    Translation:AnimalsCells
  67. Ogihara T, Isobe T, Ichimura T, Taoka M, Funaki M, Sakoda H, Onishi Y, Inukai K, Anai M, Fukushima Y, Kikuchi M, Yazaki Y, Oka Y, Asano T. 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. J Biol Chem. 1997 Oct 03; 272(40):25267-74. PMID: 9312143.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  68. Ichimura T, Ito M, Itagaki C, Takahashi M, Horigome T, Omata S, Ohno S, Isobe T. The 14-3-3 protein binds its target proteins with a common site located towards the C-terminus. FEBS Lett. 1997 Aug 18; 413(2):273-6. PMID: 9280296.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  69. Hatae T, Ichimura T, Ishida T, Sakurai T. Apical tubular network in the rat kidney proximal tubule cells studied by thick-section and scanning electron microscopy. Cell Tissue Res. 1997 May; 288(2):317-25. PMID: 9082967.
    Citations: 13     Fields:    Translation:Animals
  70. Kawahire S, Takeuchi M, Gohshi T, Sasagawa S, Shimada M, Takahashi M, Abe TK, Ueda T, Kuwano R, Hikawa A, Ichimura T, Omata S, Horigome T. cDNA cloning of nuclear localization signal binding protein NBP60, a rat homologue of lamin B receptor, and identification of binding sites of human lamin B receptor for nuclear localization signals and chromatin. J Biochem. 1997 May; 121(5):881-9. PMID: 9192729.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  71. Kashimoto K, Nagano Y, Suitani Y, Hamanaka K, Mizumoto T, Tomizaki K, Takahata H, Nagamoto A, Ohata A, Yoshihara S, Ichimura T. Structure-activity relationship studies of PACAP-27 and VIP analogues. Ann N Y Acad Sci. 1996 Dec 26; 805:505-10. PMID: 8993431.
    Citations: 3     Fields:    Translation:AnimalsCells
  72. Ichimura T, Finch PW, Zhang G, Kan M, Stevens JL. Induction of FGF-7 after kidney damage: a possible paracrine mechanism for tubule repair. Am J Physiol. 1996 Nov; 271(5 Pt 2):F967-76. PMID: 8945990.
    Citations: 14     Fields:    Translation:AnimalsCells
  73. Tanaka H, Date C, Chen H, Nakayama T, Yokoyama T, Yoshiike N, Iwaoka H, Iwaya M, Zaman MM, Yamaguchi M, Matsumura Y, Sugiyama M, Kushiro W, Ichimura T, Noji A, Chowdhury AH, Kim IS, Kwan TB, Cho BM. A brief review of epidemiological studies on ischemic heart disease in Japan. J Epidemiol. 1996 Aug; 6(3 Suppl):S49-59. PMID: 8800274.
    Citations: 4     Fields:    Translation:Humans
  74. Kawahire S, Tachibana T, Umemoto M, Yoneda Y, Imai N, Saito M, Ichimura T, Omata S, Horigome T. Subcellular distribution and phosphorylation of the nuclear localization signal binding protein, NBP60. Exp Cell Res. 1996 Feb 01; 222(2):385-94. PMID: 8598227.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  75. Ichimura T, Uchiyama J, Kunihiro O, Ito M, Horigome T, Omata S, Shinkai F, Kaji H, Isobe T. Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylase. J Biol Chem. 1995 Dec 01; 270(48):28515-8. PMID: 7499362.
    Citations: 15     Fields:    Translation:AnimalsCells
  76. Ichimura T, Maier JA, Maciag T, Zhang G, Stevens JL. FGF-1 in normal and regenerating kidney: expression in mononuclear, interstitial, and regenerating epithelial cells. Am J Physiol. 1995 Nov; 269(5 Pt 2):F653-62. PMID: 7503231.
    Citations: 10     Fields:    Translation:AnimalsCells
  77. Matsuoka K, Taoka M, Satozawa N, Nakayama H, Ichimura T, Takahashi N, Yamakuni T, Song SY, Isobe T. A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons. Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21):9670-4. PMID: 7937870; PMCID: PMC44878.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  78. Kano K, Ito S, Ichimura T. Effect of prednisone on thyroid function in children with nephrotic syndrome. Horm Metab Res. 1994 Aug; 26(8):395-6. PMID: 7806139.
    Citations: 1     Fields:    Translation:Humans
  79. Watanabe M, Isobe T, Ichimura T, Kuwano R, Takahashi Y, Kondo H, Inoue Y. Molecular cloning of rat cDNAs for the zeta and theta subtypes of 14-3-3 protein and differential distributions of their mRNAs in the brain. Brain Res Mol Brain Res. 1994 Aug; 25(1-2):113-21. PMID: 7984035.
    Citations: 24     Fields:    Translation:AnimalsCells
  80. Ito S, Kano K, Ando T, Ichimura T. Thyroid function in children with nephrotic syndrome. Pediatr Nephrol. 1994 Aug; 8(4):412-5. PMID: 7947028.
    Citations: 16     Fields:    Translation:Humans
  81. Lu G, de Vetten NC, Sehnke PC, Isobe T, Ichimura T, Fu H, van Heusden GP, Ferl RJ. A single Arabidopsis GF14 isoform possesses biochemical characteristics of diverse 14-3-3 homologues. Plant Mol Biol. 1994 Jul; 25(4):659-67. PMID: 8061318.
    Citations: 15     Fields:    Translation:AnimalsCells
  82. Zhang G, Sato JD, Herley MT, Tsang MW, Ye H, Liu H, Ichimura T, Yan G, McKeehan WL, Stevens JL. Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor. Cell Growth Differ. 1994 Apr; 5(4):349-57. PMID: 7519042.
    Citations: 1     Fields:    Translation:AnimalsCells
  83. Tanaka T, Hibi I, Shimizu N, Imura H, Tanaka K, Fukata J, Fujieda K, Ichimura T, Kuribayashi T, Ito K, et al. Evaluation of hypothalamo-pituitary-adrenocortical function in children by human corticotropin-releasing hormone (MCI-028) test. Endocr J. 1993 Oct; 40(5):581-9. PMID: 7951524.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  84. Ohsumi T, Ichimura T, Sugano H, Omata S, Isobe T, Kuwano R. Ribosome-binding protein p34 is a member of the leucine-rich-repeat-protein superfamily. Biochem J. 1993 Sep 01; 294 ( Pt 2):465-72. PMID: 7690545; PMCID: PMC1134477.
    Citations: 10     Fields:    Translation:AnimalsCells
  85. Yoshihara S, Kanno N, Ando T, Fukuda N, Abe T, Ichimura T, Yanaihara N. Involvement of substance P in the paroxysmal cough of pertussis. Regul Pept. 1993 Jul 02; 46(1-2):238-40. PMID: 7692502.
    Citations:    Fields:    Translation:Humans
  86. Zhang G, Ichimura T, Maier JA, Maciag T, Stevens JL. A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine in vivo. J Biol Chem. 1993 Jun 05; 268(16):11542-7. PMID: 7685015.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  87. Kanno N, Abe T, Asai H, Yoshihara S, Ichimura T. [Skin test reactivity to histamine in childhood]. Arerugi. 1993 May; 42(5):643-8. PMID: 8323463.
    Citations:    Fields:    Translation:Humans
  88. Watanabe M, Isobe T, Ichimura T, Kuwano R, Takahashi Y, Kondo H. Molecular cloning of rat cDNAs for beta and gamma subtypes of 14-3-3 protein and developmental changes in expression of their mRNAs in the nervous system. Brain Res Mol Brain Res. 1993 Jan; 17(1-2):135-46. PMID: 8381897.
    Citations: 18     Fields:    Translation:AnimalsCells
  89. Ichimura-Ohshima Y, Morii K, Ichimura T, Araki K, Takahashi Y, Isobe T, Minoshima S, Fukuyama R, Shimizu N, Kuwano R. cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain. J Neurosci Res. 1992 Apr; 31(4):600-5. PMID: 1578511.
    Citations: 5     Fields:    Translation:HumansCells
  90. Hayden PJ, Ichimura T, McCann DJ, Pohl LR, Stevens JL. Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J Biol Chem. 1991 Oct 05; 266(28):18415-8. PMID: 1917965.
    Citations: 14     Fields:    Translation:AnimalsCells
  91. Zhang GH, Ichimura T, Wallin A, Kan M, Stevens JL. Regulation of rat proximal tubule epithelial cell growth by fibroblast growth factors, insulin-like growth factor-1 and transforming growth factor-beta, and analysis of fibroblast growth factors in rat kidney. J Cell Physiol. 1991 Aug; 148(2):295-305. PMID: 1715345.
    Citations: 7     Fields:    Translation:AnimalsCells
  92. Watanabe M, Isobe T, Okuyama T, Ichimura T, Kuwano R, Takahashi Y, Kondo H. Molecular cloning of cDNA to rat 14-3-3 eta chain polypeptide and the neuronal expression of the mRNA in the central nervous system. Brain Res Mol Brain Res. 1991 May; 10(2):151-8. PMID: 1649368.
    Citations: 15     Fields:    Translation:AnimalsCells
  93. Isobe T, Ichimura T, Sunaya T, Okuyama T, Takahashi N, Kuwano R, Takahashi Y. Distinct forms of the protein kinase-dependent activator of tyrosine and tryptophan hydroxylases. J Mol Biol. 1991 Jan 05; 217(1):125-32. PMID: 1671102.
    Citations: 26     Fields:    Translation:AnimalsCells
  94. Asai H, Onisawa S, Furuya N, Abe T, Ichimura T. Breathing patterns in asthmatic children during attack. J Asthma. 1990; 27(4):229-36. PMID: 2211493.
    Citations: 1     Fields:    Translation:Humans
  95. Ichimura T, Isobe T, Okuyama T, Takahashi N, Araki K, Kuwano R, Takahashi Y. Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases. Proc Natl Acad Sci U S A. 1988 Oct; 85(19):7084-8. PMID: 2902623; PMCID: PMC282128.
    Citations: 81     Fields:    Translation:AnimalsCells
  96. Senju M, Komori M, Ide T, Ichimura T, Haraguchi M, Fukuda H, Mori N, Murakami K, Tomita S, Tanaka Y, et al. [Case of advanced gastric cancer with remakable gynecomastia and marked elevation of serum human chorionic gonadotropin (HCG)]. Nihon Shokakibyo Gakkai Zasshi. 1983 Jun; 80(6):1331-5. PMID: 6620659.
    Citations:    Fields:    Translation:Humans
  97. Fukuda H, Ide T, Ichimura T, Haraguchi M, Mori N, Murakami K, Makiyama K, Saito A, Hara K. [Clinical studies on the isolation of Clastridium difficile--13 cases]. Nihon Shokakibyo Gakkai Zasshi. 1983 Apr; 80(4):954-62. PMID: 6620648.
    Citations:    Fields:    Translation:HumansCells
  98. Haraguchi M, Beppu C, Komori M, Ide T, Ichimura T, Fukuda H, Mori N, Ide H, Tanioka H, Tomita S, Murakami K, Tanaka Y, Nakamura N, Makiyama K, Saito A, Hara K, Oka S, Harada N, Tsuchiya R. [A case of splenic abscess]. Nihon Shokakibyo Gakkai Zasshi. 1983 Feb; 80(2):223-7. PMID: 6865066.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.