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Ali Ajdari, Ph.D.

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Biography
Harvard Medical School, Boston, MAPostdoctoral Fellow02/2020Radiation Therapy Optimization
University of Washington, Seattle, WAPh.D.12/2017Optimization
Sharif University of Technology, IranM.Sc.02/2012Industrial & Systems Engineering
Isfahan University of Technology, IranB.Sc.02/2009Industrial & Systems Engineering

Overview
I am an Industrial Engineer and Operations Researcher by education and Cancer Researcher and Optimization expert by profession. My areas of interest is applications of optimization techniques, including convex, robust, dynamic, and stochastic optimization, in healthcare systems, especially in the world of Oncology. I heavily and routinely use state-of-the-art image analysis and data analytics techniques to extract valuable information from complex medical data (e.g. imaging, genetic, and bio-physiological) and use them in advanced data-driven optimization techniques. In particular, I am very interested in Personalized Medicine -- the personalization of standard treatment protocols based on patients' genetic and epigenetic characteristics. My overall goal is to integrate knowledge from mathematics, biology, and oncology to arrive at a fully data-informed personalized treatment plans.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ten Eikelder SCM, Ajdari A, Bortfeld T, den Hertog D. Conic formulation of fluence map optimization problems. Phys Med Biol. 2021 Nov 24; 66(22). PMID: 34587600.
    Citations:    Fields:    
  2. Ajdari A, Xie Y, Richter C, Niyazi M, Duda DG, Hong TS, Bortfeld T. Toward Personalized Radiation Therapy of Liver Metastasis: Importance of Serial Blood Biomarkers. JCO Clin Cancer Inform. 2021 03; 5:315-325. PMID: 33764817.
    Citations: 2     Fields:    Translation:HumansCells
  3. Ten Eikelder SCM, Ferjancic P, Ajdari A, Bortfeld T, den Hertog D, Jeraj R. Optimal treatment plan adaptation using mid-treatment imaging biomarkers. Phys Med Biol. 2020 12 22; 65(24):245011. PMID: 33053518.
    Citations:    Fields:    Translation:HumansAnimals
  4. McNamara AL, Hall DC, Shusharina N, Liu A, Wei X, Ajdari A, Mohan R, Liao Z, Paganetti H. Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial. Radiother Oncol. 2020 06; 147:8-14. PMID: 32224318.
    Citations: 2     Fields:    Translation:Humans
  5. Ali Ajdari Fatemeh Saberian Archis Ghate. A theoretical framework for learning tumor dose-response uncertainty in individualized spatiobiologically integrated radiotherapy, INFORMS Journal on Computing. INFORMS Journal on Computing. 2019.
  6. Ajdari A, Niyazi M, Nicolay NH, Thieke C, Jeraj R, Bortfeld T. Towards optimal stopping in radiation therapy. Radiother Oncol. 2019 05; 134:96-100. PMID: 31005230.
    Citations: 3     Fields:    Translation:Humans
  7. Ajdari A, Ghate A, Kim M. Adaptive treatment-length optimization in spatiobiologically integrated radiotherapy. Phys Med Biol. 2018 03 27; 63(7):075009. PMID: 29512510.
    Citations:    Fields:    Translation:Humans
  8. Ajdari A, Boyle LN, Kannan N, Wang J, Rivara FP, Vavilala MS. Simulation of the Emergency Department Care Process for Pediatric Traumatic Brain Injury. J Healthc Qual. 2018 Mar/Apr; 40(2):110-118. PMID: 29271801.
    Citations: 1     Fields:    Translation:Humans
  9. Ajdari A, Boyle LN, Kannan N, Rowhani-Rahbar A, Wang J, Mink R, Ries B, Wainwright M, Groner JI, Bell MJ, Giza C, Zatzick DF, Ellenbogen RG, Mitchell PH, Rivara FP, Vavilala MS. Examining Emergency Department Treatment Processes in Severe Pediatric Traumatic Brain Injury. J Healthc Qual. 2017 Nov/Dec; 39(6):334-344. PMID: 28166114.
    Citations: 4     Fields:    Translation:Humans
  10. Ali Ajdari Minsun Kim Archis Ghate. Robust spatiotemporally integrated fractionation in radiotherapy. Operations Research Letter. 2016; 44(4):544-549.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.