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Eunpyo Hong, Ph.D.

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Overview
Genetic Epidemiologic Researcher treating Biostatistics and Bioinformatics, Dr. Eunpyo Hong Ph.D. is Research fellow at the Center for Genomic Medicine in Massachusetts General Hospital, Boston MA, USA. He has graduated in Hallym University with BS in Statistics and Informatics. He also has a Ph.D. in Medical Genetics with Genetic Epidemiology and Bioinformatics strongly interested in research related to population genetics, which aim to identify gene/sequence variations and assess a risk prediction on human complex diseases such as cancers, age-related, and metabolic diseases, using candidate gene, large-scale GWAS, WES, WGS, and RNAseq dataset involved the hundreds or thousands of study populations with subsequently applying Python and Perl languages. I investigated to identify susceptibility genes and develop genetic and nongenetic risk models on human complex traits such as hsCRP, hypertension, cardiovascular disease, type 2 diabetes, tuberculosis, cancers, etc., using various statistical approaches such as polygenic/non-genetic risk scores, meta- and survival analyses, linear mixed model, and liability threshold model. Among my investigations, some papers were published during academic degrees; others are ongoing topics such as intracranial aneurysm, Huntington disorder, osteoporosis, liver functions, cancers (e.g., hepatocellular and lung carcinomas), etc. These subjects are described in more detail in my accompanying curriculum vitae (CV).

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jeon JP, Kim SE, Chai CL, Hong EP, Yang JS, Kang SH, Choi HJ, Cho YJ. Seizure incidence of angiogram-negative subarachnoid hemorrhage: An updated meta-analysis. J Chin Med Assoc. 2020 May; 83(5):466-470. PMID: 32217992.
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  2. Pan-cancer analysis of whole genomes. Nature. 2020 02; 578(7793):82-93. PMID: 32025007.
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  3. Ellis N, Tee A, McAllister B, Massey T, McLauchlan D, Stone T, Correia K, Loupe J, Kim KH, Barker D, Hong EP, Chao MJ, Long JD, Lucente D, Vonsattel JPG, Pinto RM, Elneel KA, Ramos EM, Mysore JS, Gillis T, Wheeler VC, Medway C, Hall L, Kwak S, Sampaio C, Ciosi M, Maxwell A, Chatzi A, Monckton DG, Orth M, Landwehrmeyer GB, Paulsen JS, Shoulson I, Myers RH, van Duijn E, Rickards H, MacDonald ME, Lee JM, Gusella JF, Jones L, Holmans P. Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington's Disease. Biol Psychiatry. 2020 May 01; 87(9):857-865. PMID: 32087949.
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  4. CAG Repeat Not Polyglutamine Length Determines Timing of Huntington's Disease Onset. Cell. 2019 08 08; 178(4):887-900.e14. PMID: 31398342.
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  5. Hong EP, Kim BJ, Jeon JP, Yang JS, Choi HJ, Kang SH, Cho YJ. Association of Endothelin Receptor Type A with Intracranial Aneurysm in 20,609 East Asians: An Updated Meta-Analysis. World Neurosurg. 2019 Oct; 130:e804-e814. PMID: 31295611.
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  6. Kim BJ, Kim Y, Hong EP, Jeon JP, Yang JS, Choi HJ, Kang SH, Cho YJ. Correlation Between Altered DNA Methylation of Intergenic Regions of ITPR3 and Development of Delayed Cerebral Ischemia in Patients with Subarachnoid Hemorrhage. World Neurosurg. 2019 Oct; 130:e449-e456. PMID: 31247352.
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  7. Hong EP, Kim BJ, Jeon JP. Genome-Wide Association between the 2q33.1 Locus and Intracranial Aneurysm Susceptibility: An Updated Meta-Analysis Including 18,019 Individuals. J Clin Med. 2019 May 16; 8(5). PMID: 31100866.
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  8. Kim HC, Rhim JK, Ahn JH, Park JJ, Moon JU, Hong EP, Kim MR, Kim SG, Lee SH, Jeong JH, Choi SW, Jeon JP. Machine Learning Application for Rupture Risk Assessment in Small-Sized Intracranial Aneurysm. J Clin Med. 2019 May 15; 8(5). PMID: 31096607.
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  9. Hong EP, Kim BJ, Cho SS, Yang JS, Choi HJ, Kang SH, Jeon JP. Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population. J Clin Med. 2019 Feb 25; 8(2). PMID: 30823506.
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  10. Kim SE, Hong EP, Kim HC, Lee SU, Jeon JP. Ultrasonographic optic nerve sheath diameter to detect increased intracranial pressure in adults: a meta-analysis. Acta Radiol. 2019 Feb; 60(2):221-229. PMID: 29768927.
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  11. Lee SU, Hong EP, Kim BJ, Kim SE, Jeon JP. Delayed Cerebral Ischemia and Vasospasm After Spontaneous Angiogram-Negative Subarachnoid Hemorrhage: An Updated Meta-Analysis. World Neurosurg. 2018 Jul; 115:e558-e569. PMID: 29689403.
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  12. Hong EP, Rhee KH, Kim DH, Park JW. Identification of pleiotropic genetic variants affecting osteoporosis risk in a Korean elderly cohort. J Bone Miner Metab. 2019 Jan; 37(1):43-52. PMID: 29273888.
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  13. Hong EP, Kim BJ, Kim C, Choi HJ, Jeon JP. Association of SOX17 Gene Polymorphisms and Intracranial Aneurysm: A Case-Control Study and Meta-Analysis. World Neurosurg. 2018 Feb; 110:e823-e829. PMID: 29191544.
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  14. Jeon JP, Hong EP, Kim JE, Ha EJ, Cho WS, Son YJ, Bang JS, Oh CW. Genetic Risk Assessment of Elastin Gene Polymorphisms with Intracranial Aneurysm in Koreans. Neurol Med Chir (Tokyo). 2018 Jan 15; 58(1):17-22. PMID: 29129841.
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  15. Hong EP, Jeon JP, Kim SE, Yang JS, Choi HJ, Kang SH, Cho YJ. A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans. Yonsei Med J. 2017 Sep; 58(5):1006-1011. PMID: 28792146.
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  16. Hong EP, Go MJ, Kim HL, Park JW. Risk prediction of pulmonary tuberculosis using genetic and conventional risk factors in adult Korean population. PLoS One. 2017; 12(3):e0174642. PMID: 28355295.
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  17. Hong EP, Kim DH, Suh JG, Park JW. Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations. Hypertens Res. 2014 Jul; 37(7):692-8. PMID: 24671014.
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  18. Lee BK, Mohan BR, Byeon SH, Lim KS, Hong EP. Evaluating the performance of a turbulent wet scrubber for scrubbing particulate matter. J Air Waste Manag Assoc. 2013 May; 63(5):499-506. PMID: 23786141.
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  19. Heo SG, Hong EP, Park JW. Genetic risk prediction for normal-karyotype acute myeloid leukemia using whole-exome sequencing. Genomics Inform. 2013 Mar; 11(1):46-51. PMID: 23613682.
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  20. Hong EP, Park JW. Sample size and statistical power calculation in genetic association studies. Genomics Inform. 2012 Jun; 10(2):117-22. PMID: 23105939.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.