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Steven Edward Arnold, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AG051958 (ARNOLD, STEVEN E) Sep 1, 2016 - Apr 30, 2018
    NIH/NIA
    Assessment of Brain Insulin Resistance in Alzheimer's Disease with Insulin Clamp
    Role: Principal Investigator
  2. R01NS084965 (ARVANITAKIS, ZOE) Jul 1, 2014 - Jun 30, 2019
    NIH/NINDS
    Mechanisms linking insulin resistance to brain structure, pathology, and function
    Role: Co-Principal Investigator
  3. R01AG039478 (ARNOLD, STEVEN E) Apr 1, 2011 - Mar 31, 2017
    NIH/NIA
    Targeted Proteomics of Resilient Cognition in Aging
    Role: Principal Investigator
  4. R01MH072880 (ARNOLD, STEVEN E) Aug 18, 2005 - Jan 31, 2010
    NIH/NIMH
    Neurobiology of Dysbindin in Schizophrenia and sdy Mouse
    Role: Principal Investigator
  5. R01MH059344 (ARNOLD, STEVEN E) May 1, 2000 - Apr 30, 2004
    NIH/NIMH
    OLFACTORY NEURODEVELOPMENTAL PATHOLOGY IN SCHIZOPHRENIA
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gangishetti U, Christina Howell J, Perrin RJ, Louneva N, Watts KD, Kollhoff A, Grossman M, Wolk DA, Shaw LM, Morris JC, Trojanowski JQ, Fagan AM, Arnold SE, Hu WT. Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease. Alzheimers Res Ther. 2018 Sep 25; 10(1):98. PMID: 30253800.
    View in: PubMed
  2. Carlyle BC, Trombetta BA, Arnold SE. Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias. Proteomes. 2018 Aug 31; 6(3). PMID: 30200280.
    View in: PubMed
  3. Arnold SE, Betensky RA. Multicrossover Randomized Controlled Trial Designs in Alzheimer Disease. Ann Neurol. 2018 Aug; 84(2):168-175. PMID: 30014506.
    View in: PubMed
  4. Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, Duda JE, Irwin DJ, Wolk D, Elman L, McCluskey L, Chen-Plotkin A, Weintraub D, Arnold SE, Brettschneider J, Lee VM, Trojanowski JQ. Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated. Brain. 2018 Jul 01; 141(7):2181-2193. PMID: 29878075.
    View in: PubMed
  5. Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP. 18F-florbetapir Positron Emission Tomography-determined Cerebral ß-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. 2018 04; 128(4):728-744. PMID: 29389750.
    View in: PubMed
  6. Trombetta BA, Carlyle BC, Koenig AM, Shaw LM, Trojanowski JQ, Wolk DA, Locascio JJ, Arnold SE. The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease. PLoS One. 2018; 13(3):e0193707. PMID: 29505610.
    View in: PubMed
  7. Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM, Nathan DM. Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Nat Rev Neurol. 2018 Mar; 14(3):168-181. PMID: 29377010.
    View in: PubMed
  8. Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM, Mattsson N, Kornhuber J, Sabri O, Rowe CC, Parnetti L, Popp J, Fladby T, Jagust WJ, Aalten P, Lee DY, Vandenberghe R, Resende de Oliveira C, Kapaki E, Froelich L, Ivanoiu A, Gabryelewicz T, Verbeek MM, Sanchez-Juan P, Hildebrandt H, Camus V, Zboch M, Brooks DJ, Drzezga A, Rinne JO, Newberg A, de Mendonça A, Sarazin M, Rabinovici GD, Madsen K, Kramberger MG, Nordberg A, Mok V, Mroczko B, Wolk DA, Meyer PT, Tsolaki M, Scheltens P, Verhey FRJ, Visser PJ, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BNM, Blennow K, van Buchem MA, Cavedo E, Chen K, Chipi E, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gkatzima O, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Johannsen P, Klimkowicz-Mrowiec A, Köhler S, Koglin N, van Laere K, de Leon M, Lisetti V, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Nordlund A, Novak GP, Paraskevas GP, Perera G, Peters O, Ramakers IHGB, Rami L, Rodríguez-Rodríguez E, Roe CM, Rot U, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Zetterberg H. Association of Cerebral Amyloid-ß Aggregation With Cognitive Functioning in Persons Without Dementia. JAMA Psychiatry. 2018 Jan 01; 75(1):84-95. PMID: 29188296.
    View in: PubMed
  9. Kimchi EY, Hshieh TT, Guo R, Wong B, O'Connor M, Marcantonio ER, Metzger ED, Strauss J, Arnold SE, Inouye SK, Fong TG. Consensus Approaches to Identify Incident Dementia in Cohort Studies: Systematic Review and Approach in the Successful Aging after Elective Surgery Study. J Am Med Dir Assoc. 2017 Dec 01; 18(12):1010-1018.e1. PMID: 28927945.
    View in: PubMed
  10. Lanctôt KL, Amatniek J, Ancoli-Israel S, Arnold SE, Ballard C, Cohen-Mansfield J, Ismail Z, Lyketsos C, Miller DS, Musiek E, Osorio RS, Rosenberg PB, Satlin A, Steffens D, Tariot P, Bain LJ, Carrillo MC, Hendrix JA, Jurgens H, Boot B. Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms. Alzheimers Dement (N Y). 2017 Sep; 3(3):440-449. PMID: 29067350.
    View in: PubMed
  11. Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384. PMID: 28714976.
    View in: PubMed
  12. Penna M, Hompes R, Arnold S, Wynn G, Austin R, Warusavitarne J, Moran B, Hanna GB, Mortensen NJ, Tekkis PP. Transanal Total Mesorectal Excision: International Registry Results of the First 720 Cases. Ann Surg. 2017 07; 266(1):111-117. PMID: 27735827.
    View in: PubMed
  13. Vasunilashorn SM, Dillon ST, Inouye SK, Ngo LH, Fong TG, Jones RN, Travison TG, Schmitt EM, Alsop DC, Freedman SD, Arnold SE, Metzger ED, Libermann TA, Marcantonio ER. High C-Reactive Protein Predicts Delirium Incidence, Duration, and Feature Severity After Major Noncardiac Surgery. J Am Geriatr Soc. 2017 Aug; 65(8):e109-e116. PMID: 28555781.
    View in: PubMed
  14. Carter O, Bennett D, Nash T, Arnold S, Brown L, Cai RY, Allan Z, Dluzniak A, McAnally K, Burr D, Sundram S. Sensory integration deficits support a dimensional view of psychosis and are not limited to schizophrenia. Transl Psychiatry. 2017 05 09; 7(5):e1118. PMID: 28485725.
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  15. Espeland MA, Luchsinger JA, Baker LD, Neiberg R, Kahn SE, Arnold SE, Wing RR, Blackburn GL, Bray G, Evans M, Hazuda HP, Jeffery RW, Wilson VM, Clark JM, Coday M, Demos-McDermott K, Foreyt JP, Greenway F, Hill JO, Horton ES, Jakicic JM, Johnson KC, Knowler WC, Lewis CE, Nathan DM, Peters A, Pi-Sunyer X, Pownall H, Wadden TA, Rapp SR. Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment. Neurology. 2017 May 23; 88(21):2026-2035. PMID: 28446656.
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  16. Koenig AM, Mechanic-Hamilton D, Xie SX, Combs MF, Cappola AR, Xie L, Detre JA, Wolk DA, Arnold SE. Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study. Alzheimer Dis Assoc Disord. 2017 Apr-Jun; 31(2):107-113. PMID: 28538088.
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  17. Roalf DR, Moore TM, Mechanic-Hamilton D, Wolk DA, Arnold SE, Weintraub DA, Moberg PJ. Bridging cognitive screening tests in neurologic disorders: A crosswalk between the short Montreal Cognitive Assessment and Mini-Mental State Examination. Alzheimers Dement. 2017 Aug; 13(8):947-952. PMID: 28238740.
    View in: PubMed
  18. Rapp SR, Luchsinger JA, Baker LD, Blackburn GL, Hazuda HP, Demos-McDermott KE, Jeffery RW, Keller JN, McCaffery JM, Pajewski NM, Evans M, Wadden TA, Arnold SE, Espeland MA. Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study. J Am Geriatr Soc. 2017 May; 65(5):966-972. PMID: 28067945.
    View in: PubMed
  19. Yarchoan M, James BD, Shah RC, Arvanitakis Z, Wilson RS, Schneider J, Bennett DA, Arnold SE. Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology. J Alzheimers Dis. 2017; 56(2):699-706. PMID: 28035936.
    View in: PubMed
  20. Quarmley M, Moberg PJ, Mechanic-Hamilton D, Kabadi S, Arnold SE, Wolk DA, Roalf DR. Odor Identification Screening Improves Diagnostic Classification in Incipient Alzheimer's Disease. J Alzheimers Dis. 2017; 55(4):1497-1507. PMID: 27886011.
    View in: PubMed
  21. Pruzin JJ, Schneider JA, Capuano AW, Leurgans SE, Barnes LL, Ahima RS, Arnold SE, Bennett DA, Arvanitakis Z. Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology. Alzheimer Dis Assoc Disord. 2017 Jan-Mar; 31(1):41-47. PMID: 27755004.
    View in: PubMed
  22. Roalf DR, Quarmley M, Mechanic-Hamilton D, Wolk DA, Arnold SE, Moberg PJ. Within-Individual Variability: An Index for Subtle Change in Neurocognition in Mild Cognitive Impairment. J Alzheimers Dis. 2016 08 10; 54(1):325-35. PMID: 27567827.
    View in: PubMed
  23. Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM. Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models. Front Behav Neurosci. 2016; 10:136. PMID: 27445731.
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  24. Roalf DR, Moore TM, Wolk DA, Arnold SE, Mechanic-Hamilton D, Rick J, Kabadi S, Ruparel K, Chen-Plotkin AS, Chahine LM, Dahodwala NA, Duda JE, Weintraub DA, Moberg PJ. Defining and validating a short form Montreal Cognitive Assessment (s-MoCA) for use in neurodegenerative disease. J Neurol Neurosurg Psychiatry. 2016 12; 87(12):1303-1310. PMID: 27071646.
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  25. Dillon ST, Vasunilashorn SM, Ngo L, Otu HH, Inouye SK, Jones RN, Alsop DC, Kuchel GA, Metzger ED, Arnold SE, Marcantonio ER, Libermann TA. Higher C-Reactive Protein Levels Predict Postoperative Delirium in Older Patients Undergoing Major Elective Surgery: A Longitudinal Nested Case-Control Study. Biol Psychiatry. 2017 01 15; 81(2):145-153. PMID: 27160518.
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  26. Chen Y, Bang S, McMullen MF, Kazi H, Talbot K, Ho MX, Carlson G, Arnold SE, Ong WY, Kim SF. Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia. Mol Neurobiol. 2017 04; 54(3):1699-1709. PMID: 26873854.
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  27. Camacho-Mercado CL, Figueroa R, Acosta H, Arnold SE, Vega IE. Profiling of Alzheimer's disease patients in Puerto Rico: A comparison of two distinct socioeconomic areas. SAGE Open Med. 2016; 4:2050312115627826. PMID: 26893902; PMCID: PMC4737973.
  28. Koenig AM, Arnold SE, Streim JE. Agitation and Irritability in Alzheimer's Disease: Evidenced-Based Treatments and the Black-Box Warning. Curr Psychiatry Rep. 2016 Jan; 18(1):3. PMID: 26695173.
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  29. Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, Adler CH, Beach TG, Trojanowski JQ. Pathological a-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathol. 2016 Mar; 131(3):393-409. PMID: 26721587; PMCID: PMC4754135 [Available on 03/01/17].
  30. Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ. Deep clinical and neuropathological phenotyping of Pick disease. Ann Neurol. 2016 Feb; 79(2):272-87. PMID: 26583316; PMCID: PMC4755803 [Available on 02/01/17].
  31. Irwin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ. Semi-Automated Digital Image Analysis of Pick's Disease and TDP-43 Proteinopathy. J Histochem Cytochem. 2016 01; 64(1):54-66. PMID: 26538548; PMCID: PMC4810792 [Available on 01/01/17].
  32. Cecchi M, Moore DK, Sadowsky CH, Solomon PR, Doraiswamy PM, Smith CD, Jicha GA, Budson AE, Arnold SE, Fadem KC. A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings. Alzheimers Dement (Amst). 2015 Dec; 1(4):387-94. PMID: 27239520.
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  33. Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, Soares HD, Kling MA, Mailman M, Arnold SE, Narayan VA, Lee VM, Shaw LM, Baker D, Wittenberg GM, Trojanowski JQ, Wang LS. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study. Alzheimers Dement (Amst). 2015 Sep 01; 1(3):339-348. PMID: 26693175.
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  34. Egbujo CN, Sinclair D, Borgmann-Winter KE, Arnold SE, Turetsky BI, Hahn CG. Molecular evidence for decreased synaptic efficacy in the postmortem olfactory bulb of individuals with schizophrenia. Schizophr Res. 2015 Oct; 168(1-2):554-62. PMID: 26260078.
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  35. Meeks S, Van Haitsma K, Mast BT, Arnold S, Streim JE, Sephton S, Smith PJ, Kleban M, Rovine M. Psychological and social resources relate to biomarkers of allostasis in newly admitted nursing home residents. Aging Ment Health. 2016; 20(1):88-99. PMID: 26237175; PMCID: PMC4628586 [Available on 01/01/17].
  36. Toledo JB, Bjerke M, Chen K, Rozycki M, Jack CR, Weiner MW, Arnold SE, Reiman EM, Davatzikos C, Shaw LM, Trojanowski JQ. Memory, executive, and multidomain subtle cognitive impairment: clinical and biomarker findings. Neurology. 2015 Jul 14; 85(2):144-53. PMID: 26085606.
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  37. Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NC, Yoon H, Kim J, Fujioka S, McLean CA, Ghetti B, Spina S, Cantwell LB, Farlow MR, Grafman J, Huey ED, Ryung Han M, Beecher S, Geller ET, Kretzschmar HA, Roeber S, Gearing M, Juncos JL, Vonsattel JP, Van Deerlin VM, Grossman M, Hurtig HI, Gross RG, Arnold SE, Trojanowski JQ, Lee VM, Wenning GK, White CL, Höglinger GU, Müller U, Devlin B, Golbe LI, Crook J, Parisi JE, Boeve BF, Josephs KA, Wszolek ZK, Uitti RJ, Graff-Radford NR, Litvan I, Younkin SG, Wang LS, Ertekin-Taner N, Rademakers R, Hakonarsen H, Schellenberg GD, Dickson DW. Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy. Nat Commun. 2015 Jun 16; 6:7247. PMID: 26077951; PMCID: PMC4469997.
  38. Negash S, Kliot D, Howard DV, Howard JH, Das SR, Yushkevich PA, Pluta JB, Arnold SE, Wolk DA. Relationship of contextual cueing and hippocampal volume in amnestic mild cognitive impairment patients and cognitively normal older adults. J Int Neuropsychol Soc. 2015 Apr; 21(4):285-96. PMID: 25991413; PMCID: PMC4596722.
  39. Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BN, Bibeau K, Blennow K, Brooks DJ, van Buchem MA, Camus V, Cavedo E, Chen K, Chetelat G, Cohen AD, Drzezga A, Engelborghs S, Fagan AM, Fladby T, Fleisher AS, van der Flier WM, Ford L, Förster S, Fortea J, Foskett N, Frederiksen KS, Freund-Levi Y, Frisoni GB, Froelich L, Gabryelewicz T, Gill KD, Gkatzima O, Gómez-Tortosa E, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Hildebrandt H, Ishihara L, Ivanoiu A, Jagust WJ, Johannsen P, Kandimalla R, Kapaki E, Klimkowicz-Mrowiec A, Klunk WE, Köhler S, Koglin N, Kornhuber J, Kramberger MG, Van Laere K, Landau SM, Lee DY, de Leon M, Lisetti V, Lleó A, Madsen K, Maier W, Marcusson J, Mattsson N, de Mendonça A, Meulenbroek O, Meyer PT, Mintun MA, Mok V, Molinuevo JL, Møllergård HM, Morris JC, Mroczko B, Van der Mussele S, Na DL, Newberg A, Nordberg A, Nordlund A, Novak GP, Paraskevas GP, Parnetti L, Perera G, Peters O, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Resende de Oliveira C, Rinne JO, Rodrigue KM, Rodríguez-Rodríguez E, Roe CM, Rot U, Rowe CC, Rüther E, Sabri O, Sanchez-Juan P, Santana I, Sarazin M, Schröder J, Schütte C, Seo SW, Soetewey F, Soininen H, Spiru L, Struyfs H, Teunissen CE, Tsolaki M, Vandenberghe R, Verbeek MM, Villemagne VL, Vos SJ, van Waalwijk van Doorn LJ, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Zboch M, Zetterberg H. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. JAMA. 2015 May 19; 313(19):1924-38. PMID: 25988462; PMCID: PMC4486209.
  40. Moelter ST, Glenn MA, Xie SX, Chittams J, Clark CM, Watson M, Arnold SE. The Dementia Severity Rating Scale predicts clinical dementia rating sum of boxes scores. Alzheimer Dis Assoc Disord. 2015 Apr-Jun; 29(2):158-60. PMID: 24770371; PMCID: PMC4208973.
  41. Das SR, Mancuso L, Olson IR, Arnold SE, Wolk DA. Short-Term Memory Depends on Dissociable Medial Temporal Lobe Regions in Amnestic Mild Cognitive Impairment. Cereb Cortex. 2016 May; 26(5):2006-17. PMID: 25725042.
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  43. Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, Zukin RS, Woo NH, Tranfaglia MR, Louneva N, Arnold SE, Siegel SJ, Bolduc FV, McDonald TV, Jongens TA, McBride SM. PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome. J Neurosci. 2015 Jan 07; 35(1):396-408. PMID: 25568131.
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  44. Koenig AM, DeLozier IJ, Zmuda MD, Marron MM, Begley AE, Anderson SJ, Reynolds CF, Arnold SE, Becker JT, Butters MA. Neuropsychological functioning in the acute and remitted States of late-life depression. J Alzheimers Dis. 2015; 45(1):175-85. PMID: 25471193; PMCID: PMC4675725.
  45. Kandel BM, Avants BB, Gee JC, Arnold SE, Wolk DA. Neuropsychological Testing Predicts Cerebrospinal Fluid Amyloid-ß in Mild Cognitive Impairment. J Alzheimers Dis. 2015; 46(4):901-12. PMID: 25881908; PMCID: PMC4699841.
  46. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. PMID: 25199842.
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  47. Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee A, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein T, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, White CL, Wisniewski T, Woltjer RL, Yamada M, Nelson PT. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014 Dec; 128(6):755-66. PMID: 25348064; PMCID: PMC4257842.
  48. Banerjee A, Wang HY, Borgmann-Winter KE, MacDonald ML, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Sleiman P, Chang X, Hakonarson H, Gur RE, Hahn CG. Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia. Mol Psychiatry. 2015 Sep; 20(9):1091-100. PMID: 25330739.
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  49. Yarchoan M, Toledo JB, Lee EB, Arvanitakis Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ, Arnold SE. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014 Nov; 128(5):679-89. PMID: 25107476; PMCID: PMC4304658.
  50. Steinberg SI, Sammel MD, Harel BT, Schembri A, Policastro C, Bogner HR, Negash S, Arnold SE. Exercise, sedentary pastimes, and cognitive performance in healthy older adults. Am J Alzheimers Dis Other Demen. 2015 May; 30(3):290-8. PMID: 25100746; PMCID: PMC4617764.
  51. Wilson RS, Capuano AW, Boyle PA, Hoganson GM, Hizel LP, Shah RC, Nag S, Schneider JA, Arnold SE, Bennett DA. Clinical-pathologic study of depressive symptoms and cognitive decline in old age. Neurology. 2014 Aug 19; 83(8):702-9. PMID: 25080520; PMCID: PMC4150132.
  52. Irwin DJ, McMillan CT, Suh E, Powers J, Rascovsky K, Wood EM, Toledo JB, Arnold SE, Lee VM, Van Deerlin VM, Trojanowski JQ, Grossman M. Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia. Neurology. 2014 Aug 05; 83(6):502-9. PMID: 24994843; PMCID: PMC4141997.
  53. Yarchoan M, Arnold SE. Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease. Diabetes. 2014 Jul; 63(7):2253-61. PMID: 24931035; PMCID: PMC4066335.
  54. Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH. A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. J Neuropathol Exp Neurol. 2014 May; 73(5):467-73. PMID: 24709683; PMCID: PMC4109801.
  55. Arnold SE, Lucki I, Brookshire BR, Carlson GC, Browne CA, Kazi H, Bang S, Choi BR, Chen Y, McMullen MF, Kim SF. High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice. Neurobiol Dis. 2014 Jul; 67:79-87. PMID: 24686304; PMCID: PMC4083060.
  56. Toledo JB, Weiner MW, Wolk DA, Da X, Chen K, Arnold SE, Jagust W, Jack C, Reiman EM, Davatzikos C, Shaw LM, Trojanowski JQ. Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition. Acta Neuropathol Commun. 2014 Mar 06; 2:26. PMID: 24602322; PMCID: PMC4008258.
  57. Toledo JB, Da X, Weiner MW, Wolk DA, Xie SX, Arnold SE, Davatzikos C, Shaw LM, Trojanowski JQ. CSF Apo-E levels associate with cognitive decline and MRI changes. Acta Neuropathol. 2014 May; 127(5):621-32. PMID: 24385135; PMCID: PMC3988233.
  58. Korecka M, Waligorska T, Figurski M, Toledo JB, Arnold SE, Grossman M, Trojanowski JQ, Shaw LM. Qualification of a surrogate matrix-based absolute quantification method for amyloid-ß42 in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry. J Alzheimers Dis. 2014; 41(2):441-51. PMID: 24625802; PMCID: PMC4159707.
  59. Bennett DA, Arnold SE, Valenzuela MJ, Brayne C, Schneider JA. Cognitive and social lifestyle: links with neuropathology and cognition in late life. Acta Neuropathol. 2014 Jan; 127(1):137-50. PMID: 24356982; PMCID: PMC4054865.
  60. Segrave RA, Arnold S, Hoy K, Fitzgerald PB. Concurrent cognitive control training augments the antidepressant efficacy of tDCS: a pilot study. Brain Stimul. 2014 Mar-Apr; 7(2):325-31. PMID: 24486425.
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  61. Arnold SE, Toledo JB, Appleby DH, Xie SX, Wang LS, Baek Y, Wolk DA, Lee EB, Miller BL, Lee VM, Trojanowski JQ. Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases. J Comp Neurol. 2013 Dec 15; 521(18):4339-55. PMID: 23881776; PMCID: PMC3872132.
  62. Wolk DA, Manning K, Kliot D, Arnold SE. Recognition memory in amnestic-mild cognitive impairment: insights from event-related potentials. Front Aging Neurosci. 2013; 5:89. PMID: 24376418; PMCID: PMC3858817.
  63. Steinberg SI, Negash S, Sammel MD, Bogner H, Harel BT, Livney MG, McCoubrey H, Wolk DA, Kling MA, Arnold SE. Subjective memory complaints, cognitive performance, and psychological factors in healthy older adults. Am J Alzheimers Dis Other Demen. 2013 Dec; 28(8):776-83. PMID: 24363073; PMCID: PMC4617766.
  64. Wilson RS, Nag S, Boyle PA, Hizel LP, Yu L, Buchman AS, Shah RC, Schneider JA, Arnold SE, Bennett DA. Brainstem aminergic nuclei and late-life depressive symptoms. JAMA Psychiatry. 2013 Dec; 70(12):1320-8. PMID: 24132763; PMCID: PMC3856195.
  65. Richardson K, Schoen M, French B, Umscheid CA, Mitchell MD, Arnold SE, Heidenreich PA, Rader DJ, deGoma EM. Statins and cognitive function: a systematic review. Ann Intern Med. 2013 Nov 19; 159(10):688-97. PMID: 24247674.
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  66. Adler BL, Yarchoan M, Hwang HM, Louneva N, Blair JA, Palm R, Smith MA, Lee HG, Arnold SE, Casadesus G. Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition. Neurobiol Aging. 2014 Apr; 35(4):793-801. PMID: 24239383.
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  67. Negash S, Wilson RS, Leurgans SE, Wolk DA, Schneider JA, Buchman AS, Bennett DA, Arnold SE. Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition. Curr Alzheimer Res. 2013 Oct; 10(8):844-51. PMID: 23919768; PMCID: PMC4060425.
  68. Pantazopoulos H, Boyer-Boiteau A, Holbrook EH, Jang W, Hahn CG, Arnold SE, Berretta S. Proteoglycan abnormalities in olfactory epithelium tissue from subjects diagnosed with schizophrenia. Schizophr Res. 2013 Nov; 150(2-3):366-72. PMID: 24035561; PMCID: PMC4215560.
  69. Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SX, McBride J, Wood EM, Schuck T, Irwin DJ, Gross RG, Hurtig H, McCluskey L, Elman L, Karlawish J, Schellenberg G, Chen-Plotkin A, Wolk D, Grossman M, Arnold SE, Shaw LM, Lee VM, Trojanowski JQ. A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimers Dement. 2014 Jul; 10(4):477-484.e1. PMID: 23978324.
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  70. Yarchoan M, Louneva N, Xie SX, Swenson FJ, Hu W, Soares H, Trojanowski JQ, Lee VM, Kling MA, Shaw LM, Chen-Plotkin A, Wolk DA, Arnold SE. Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease. J Neurol Sci. 2013 Oct 15; 333(1-2):9-12. PMID: 23978419; PMCID: PMC3815534.
  71. Irwin DJ, Cohen TJ, Grossman M, Arnold SE, McCarty-Wood E, Van Deerlin VM, Lee VM, Trojanowski JQ. Acetylated tau neuropathology in sporadic and hereditary tauopathies. Am J Pathol. 2013 Aug; 183(2):344-51. PMID: 23885714; PMCID: PMC3730769.
  72. Toledo JB, Arnold SE, Raible K, Brettschneider J, Xie SX, Grossman M, Monsell SE, Kukull WA, Trojanowski JQ. Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre. Brain. 2013 Sep; 136(Pt 9):2697-706. PMID: 23842566; PMCID: PMC3858112.
  73. Motsinger-Reif AA, Zhu H, Kling MA, Matson W, Sharma S, Fiehn O, Reif DM, Appleby DH, Doraiswamy PM, Trojanowski JQ, Kaddurah-Daouk R, Arnold SE. Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer's disease from normal cognitive aging. Acta Neuropathol Commun. 2013 Jun 27; 1:28. PMID: 24252434; PMCID: PMC3893491.
  74. Wang Z, Das SR, Xie SX, Arnold SE, Detre JA, Wolk DA. Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study. Neuroimage Clin. 2013; 2:630-6. PMID: 24179814; PMCID: PMC3777751.
  75. Kaddurah-Daouk R, Zhu H, Sharma S, Bogdanov M, Rozen SG, Matson W, Oki NO, Motsinger-Reif AA, Churchill E, Lei Z, Appleby D, Kling MA, Trojanowski JQ, Doraiswamy PM, Arnold SE. Alterations in metabolic pathways and networks in Alzheimer's disease. Transl Psychiatry. 2013 Apr 09; 3:e244. PMID: 23571809; PMCID: PMC3641405.
  76. Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC, Goate AM. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68. PMID: 23562540.
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  77. Berlau DJ, Corrada MM, Robinson JL, Geser F, Arnold SE, Lee VM, Kawas CH, Trojanowski JQ. Neocortical ß-amyloid area is associated with dementia and APOE in the oldest-old. Alzheimers Dement. 2013 Nov; 9(6):699-705. PMID: 23474043.
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  78. Wolk DA, Mancuso L, Kliot D, Arnold SE, Dickerson BC. Familiarity-based memory as an early cognitive marker of preclinical and prodromal AD. Neuropsychologia. 2013 May; 51(6):1094-102. PMID: 23474075; PMCID: PMC3742759.
  79. Müntinga H, Ahlers H, Krutzik M, Wenzlawski A, Arnold S, Becker D, Bongs K, Dittus H, Duncker H, Gaaloul N, Gherasim C, Giese E, Grzeschik C, Hänsch TW, Hellmig O, Herr W, Herrmann S, Kajari E, Kleinert S, Lämmerzahl C, Lewoczko-Adamczyk W, Malcolm J, Meyer N, Nolte R, Peters A, Popp M, Reichel J, Roura A, Rudolph J, Schiemangk M, Schneider M, Seidel ST, Sengstock K, Tamma V, Valenzuela T, Vogel A, Walser R, Wendrich T, Windpassinger P, Zeller W, van Zoest T, Ertmer W, Schleich WP, Rasel EM. Interferometry with Bose-Einstein condensates in microgravity. Phys Rev Lett. 2013 Mar 01; 110(9):093602. PMID: 23496709.
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  80. Seligman SC, Kamath V, Giovannetti T, Arnold SE, Moberg PJ. Olfaction and apathy in Alzheimer's disease, mild cognitive impairment, and healthy older adults. Aging Ment Health. 2013; 17(5):564-70. PMID: 23398350; PMCID: PMC3664659.
  81. Toledo JB, Da X, Bhatt P, Wolk DA, Arnold SE, Shaw LM, Trojanowski JQ, Davatzikos C. Relationship between plasma analytes and SPARE-AD defined brain atrophy patterns in ADNI. PLoS One. 2013; 8(2):e55531. PMID: 23408997; PMCID: PMC3568142.
  82. Mathews SB, Arnold SE, Epperson CN. Hospitalization and cognitive decline: Can the nature of the relationship be deciphered? Am J Geriatr Psychiatry. 2014 May; 22(5):465-80. PMID: 23567430; PMCID: PMC4080837.
  83. Buchman AS, Boyle PA, Wilson RS, Leurgans SE, Arnold SE, Bennett DA. Neuroticism, extraversion, and motor function in community-dwelling older persons. Am J Geriatr Psychiatry. 2013 Feb; 21(2):145-54. PMID: 23343488; PMCID: PMC3406259.
  84. Arnold SE, Vega IE, Karlawish JH, Wolk DA, Nunez J, Negron M, Xie SX, Wang LS, Dubroff JG, McCarty-Wood E, Trojanowski JQ, Van Deerlin V. Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia. J Alzheimers Dis. 2013; 33(4):1089-95. PMID: 23114514; PMCID: PMC3575080.
  85. Roalf DR, Moberg PJ, Xie SX, Wolk DA, Moelter ST, Arnold SE. Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging. Alzheimers Dement. 2013 Sep; 9(5):529-37. PMID: 23260866; PMCID: PMC4036230.
  86. Yarchoan M, Xie SX, Kling MA, Toledo JB, Wolk DA, Lee EB, Van Deerlin V, Lee VM, Trojanowski JQ, Arnold SE. Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias. Brain. 2012 Dec; 135(Pt 12):3749-56. PMID: 23204143; PMCID: PMC3577102.
  87. Kling MA, Trojanowski JQ, Wolk DA, Lee VM, Arnold SE. Vascular disease and dementias: paradigm shifts to drive research in new directions. Alzheimers Dement. 2013 Jan; 9(1):76-92. PMID: 23183137; PMCID: PMC3640817.
  88. De Jesús-Cortés HJ, Nogueras-Ortiz CJ, Gearing M, Arnold SE, Vega IE. Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration. Neuroreport. 2012 Nov 14; 23(16):942-6. PMID: 22975846; PMCID: PMC3696496.
  89. Negash S, Xie S, Davatzikos C, Clark CM, Trojanowski JQ, Shaw LM, Wolk DA, Arnold SE. Cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology. Alzheimers Dement. 2013 May; 9(3):e89-95. PMID: 23127468; PMCID: PMC3640705.
  90. Trojanowski JQ, Arnold SE, Karlawish JH, Naylor M, Brunden KR, Lee VM. A model for improving the treatment and care of Alzheimer's disease patients through interdisciplinary research. Alzheimers Dement. 2012 Nov; 8(6):564-73. PMID: 23102127; PMCID: PMC3643202.
  91. Irwin DJ, McMillan CT, Brettschneider J, Libon DJ, Powers J, Rascovsky K, Toledo JB, Boller A, Bekisz J, Chandrasekaran K, Wood EM, Shaw LM, Woo JH, Cook PA, Wolk DA, Arnold SE, Van Deerlin VM, McCluskey LF, Elman L, Lee VM, Trojanowski JQ, Grossman M. Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2013 Feb; 84(2):163-9. PMID: 23117491; PMCID: PMC3543474.
  92. Rinne JO, Wong DF, Wolk DA, Leinonen V, Arnold SE, Buckley C, Smith A, McLain R, Sherwin PF, Farrar G, Kailajärvi M, Grachev ID. [(18)F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid ß detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies. Acta Neuropathol. 2012 Dec; 124(6):833-45. PMID: 23053137.
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  93. Naylor MD, Karlawish JH, Arnold SE, Khachaturian AS, Khachaturian ZS, Lee VM, Baumgart M, Banerjee S, Beck C, Blennow K, Brookmeyer R, Brunden KR, Buckwalter KC, Comer M, Covinsky K, Feinberg LF, Frisoni G, Green C, Guimaraes RM, Gwyther LP, Hefti FF, Hutton M, Kawas C, Kent DM, Kuller L, Langa KM, Mahley RW, Maslow K, Masters CL, Meier DE, Neumann PJ, Paul SM, Petersen RC, Sager MA, Sano M, Schenk D, Soares H, Sperling RA, Stahl SM, van Deerlin V, Stern Y, Weir D, Wolk DA, Trojanowski JQ. Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit. Alzheimers Dement. 2012 Sep; 8(5):445-52. PMID: 22959699.
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  94. Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, Elman L, Karlawish J, Chen-Plotkin A, Hurtig HI, Siderowf A, Swenson F, Lee VM, Morris JC, Trojanowski JQ, Soares H. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology. 2012 Aug 28; 79(9):897-905. PMID: 22855860; PMCID: PMC3425844.
  95. Irwin DJ, McMillan CT, Toledo JB, Arnold SE, Shaw LM, Wang LS, Van Deerlin V, Lee VM, Trojanowski JQ, Grossman M. Comparison of cerebrospinal fluid levels of tau and Aß 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms. Arch Neurol. 2012 Aug; 69(8):1018-25. PMID: 22490326; PMCID: PMC3528180.
  96. Wolk DA, Zhang Z, Boudhar S, Clark CM, Pontecorvo MJ, Arnold SE. Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography. J Neurol Neurosurg Psychiatry. 2012 Sep; 83(9):923-6. PMID: 22791901; PMCID: PMC4479493.
  97. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. PMID: 22722634.
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  98. Farlow M, Arnold SE, van Dyck CH, Aisen PS, Snider BJ, Porsteinsson AP, Friedrich S, Dean RA, Gonzales C, Sethuraman G, DeMattos RB, Mohs R, Paul SM, Siemers ER. Safety and biomarker effects of solanezumab in patients with Alzheimer's disease. Alzheimers Dement. 2012 Jul; 8(4):261-71. PMID: 22672770.
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  99. Newberg AB, Arnold SE, Wintering N, Rovner BW, Alavi A. Initial clinical comparison of 18F-florbetapir and 18F-FDG PET in patients with Alzheimer disease and controls. J Nucl Med. 2012 Jun; 53(6):902-7. PMID: 22577238.
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  100. Arnold SE, Louneva N, Cao K, Wang LS, Han LY, Wolk DA, Negash S, Leurgans SE, Schneider JA, Buchman AS, Wilson RS, Bennett DA. Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease. Neurobiol Aging. 2013 Jan; 34(1):157-68. PMID: 22554416; PMCID: PMC3478410.
  101. Toledo JB, Brettschneider J, Grossman M, Arnold SE, Hu WT, Xie SX, Lee VM, Shaw LM, Trojanowski JQ. CSF biomarkers cutoffs: the importance of coincident neuropathological diseases. Acta Neuropathol. 2012 Jul; 124(1):23-35. PMID: 22526019; PMCID: PMC3551449.
  102. Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest. 2012 Apr; 122(4):1316-38. PMID: 22476197; PMCID: PMC3314463.
  103. Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aß oligomers. J Clin Invest. 2012 Apr; 122(4):1339-53. PMID: 22476196; PMCID: PMC3314445.
  104. Patel S, Lee EB, Xie SX, Law A, Jackson EM, Arnold SE, Clark CM, Shaw LM, Grady MS, Trojanowski JQ, Hamilton RH. Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus. Fluids Barriers CNS. 2012 Mar 23; 9(1):7. PMID: 22444461; PMCID: PMC3353832.
  105. Irwin DJ, Cohen TJ, Grossman M, Arnold SE, Xie SX, Lee VM, Trojanowski JQ. Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies. Brain. 2012 Mar; 135(Pt 3):807-18. PMID: 22366796; PMCID: PMC3286338.
  106. Taylor MB, Bromham NR, Arnold SE. Carcinoma of unknown primary: key radiological issues from the recent National Institute for Health and Clinical Excellence guidelines. Br J Radiol. 2012 Jun; 85(1014):661-71. PMID: 22374278; PMCID: PMC3474101.
  107. Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Weiner M, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee TY, Bartha R, Johnson S, Asthana S, Carlsson CM, Potkin SG, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre DW, Kataki M, Zimmerman EA, Celmins D, Brown AD, Pearlson GD, Blank K, Anderson K, Santulli RB, Schwartz ES, Sink KM, Williamson JD, Garg P, Watkins F, Ott BR, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen HJ, Miller BL, Mintzer J, Longmire CF, Spicer K, Finger E, Rachinsky I, Drost D, Jernigan T, McCabe C, Grant E, Ernst T, Kuperman J, Chung Y, Murray S, Bloss C, Darst B, Pritchett L, Saito A, Amaral D, DiNino M, Eyngorina B, Sowell E, Houston S, Soderberg L, Kaufmann W, van Zijl P, Rizzo-Busack H, Javid M, Mehta N, Ruberry E, Powers A, Rosen B, Gebhard N, Manigan H, Frazier J, Kennedy D, Yakutis L, Hill M, Gruen J, Bosson-Heenan J, Carlson H. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90. PMID: 22343285.
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  108. Chin AL, Negash S, Xie S, Arnold SE, Hamilton R. Quality, and not just quantity, of education accounts for differences in psychometric performance between african americans and white non-hispanics with Alzheimer's disease. J Int Neuropsychol Soc. 2012 Mar; 18(2):277-85. PMID: 22300593; PMCID: PMC3685288.
  109. Buchman AS, Shulman JM, Nag S, Leurgans SE, Arnold SE, Morris MC, Schneider JA, Bennett DA. Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol. 2012 Feb; 71(2):258-66. PMID: 22367997; PMCID: PMC3367476.
  110. Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, Wilson RS, Shaw LM. Plasma biomarkers of depressive symptoms in older adults. Transl Psychiatry. 2012 Jan 03; 2:e65. PMID: 22832727; PMCID: PMC3309547.
  111. Zhang Q, Stafford RB, Wang Z, Arnold SE, Wolk DA, Detre JA. Microvascular perfusion based on arterial spin labeled perfusion MRI as a measure of vascular risk in Alzheimer's disease. J Alzheimers Dis. 2012; 32(3):677-87. PMID: 22886015.
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  112. Glass DJ, Arnold SE. Some evolutionary perspectives on Alzheimer's disease pathogenesis and pathology. Alzheimers Dement. 2012 Jul; 8(4):343-51. PMID: 22137143; PMCID: PMC3646265.
  113. Robinson JL, Geser F, Corrada MM, Berlau DJ, Arnold SE, Lee VM, Kawas CH, Trojanowski JQ. Neocortical and hippocampal amyloid-ß and tau measures associate with dementia in the oldest-old. Brain. 2011 Dec; 134(Pt 12):3708-15. PMID: 22120149; PMCID: PMC3235569.
  114. Chen Y, Wolk DA, Reddin JS, Korczykowski M, Martinez PM, Musiek ES, Newberg AB, Julin P, Arnold SE, Greenberg JH, Detre JA. Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease. Neurology. 2011 Nov 29; 77(22):1977-85. PMID: 22094481; PMCID: PMC3235355.
  115. Musiek ES, Chen Y, Korczykowski M, Saboury B, Martinez PM, Reddin JS, Alavi A, Kimberg DY, Wolk DA, Julin P, Newberg AB, Arnold SE, Detre JA. Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer's disease. Alzheimers Dement. 2012 Jan; 8(1):51-9. PMID: 22018493; PMCID: PMC3264701.
  116. Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ. Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E962-70. PMID: 21969553; PMCID: PMC3203764.
  117. Wilson RS, Boyle PA, Buchman AS, Yu L, Arnold SE, Bennett DA. Harm avoidance and risk of Alzheimer's disease. Psychosom Med. 2011 Oct; 73(8):690-6. PMID: 21949425; PMCID: PMC3304581.
  118. Doyle GA, Wang MJ, Chou AD, Oleynick JU, Arnold SE, Buono RJ, Ferraro TN, Berrettini WH. In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression. PLoS One. 2011; 6(8):e23373. PMID: 21858091; PMCID: PMC3155531.
  119. Wolk DA, Grachev ID, Buckley C, Kazi H, Grady MS, Trojanowski JQ, Hamilton RH, Sherwin P, McLain R, Arnold SE. Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology. Arch Neurol. 2011 Nov; 68(11):1398-403. PMID: 21747004; PMCID: PMC4532383.
  120. Xie SX, Baek Y, Grossman M, Arnold SE, Karlawish J, Siderowf A, Hurtig H, Elman L, McCluskey L, Van Deerlin V, Lee VM, Trojanowski JQ. Building an integrated neurodegenerative disease database at an academic health center. Alzheimers Dement. 2011 Jul; 7(4):e84-93. PMID: 21784346; PMCID: PMC3145967.
  121. Negash S, Bennett DA, Wilson RS, Schneider JA, Arnold SE. Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project. Curr Alzheimer Res. 2011 Jun; 8(4):336-40. PMID: 21222592; PMCID: PMC3157574.
  122. Livney MG, Clark CM, Karlawish JH, Cartmell S, Negrón M, Nuñez J, Xie SX, Entenza-Cabrera F, Vega IE, Arnold SE. Ethnoracial differences in the clinical characteristics of Alzheimer's disease at initial presentation at an urban Alzheimer's disease center. Am J Geriatr Psychiatry. 2011 May; 19(5):430-9. PMID: 21522051; PMCID: PMC3085004.
  123. Buchman AS, Leurgans SE, Boyle PA, Schneider JA, Arnold SE, Bennett DA. Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study. BMC Med. 2011 Apr 20; 9:42. PMID: 21507235; PMCID: PMC3100235.
  124. Cohen JW, Louneva N, Han LY, Hodes GE, Wilson RS, Bennett DA, Lucki I, Arnold SE. Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain. Synapse. 2011 Aug; 65(8):763-70. PMID: 21190219; PMCID: PMC3401554.
  125. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. PMID: 21460841.
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  126. Talbot K, Louneva N, Cohen JW, Kazi H, Blake DJ, Arnold SE. Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location. PLoS One. 2011 Mar 01; 6(3):e16886. PMID: 21390302; PMCID: PMC3046962.
  127. Wilson RS, Yu L, Schneider JA, Arnold SE, Buchman AS, Bennett DA. Lewy bodies and olfactory dysfunction in old age. Chem Senses. 2011 May; 36(4):367-73. PMID: 21257733; PMCID: PMC3073534.
  128. Gabel MJ, Foster NL, Heidebrink JL, Higdon R, Aizenstein HJ, Arnold SE, Barbas NR, Boeve BF, Burke JR, Clark CM, Dekosky ST, Farlow MR, Jagust WJ, Kawas CH, Koeppe RA, Leverenz JB, Lipton AM, Peskind ER, Turner RS, Womack KB, Zamrini EY. Validation of consensus panel diagnosis in dementia. Arch Neurol. 2010 Dec; 67(12):1506-12. PMID: 21149812; PMCID: PMC3178413.
  129. Chen-Plotkin AS, Hu WT, Siderowf A, Weintraub D, Goldmann Gross R, Hurtig HI, Xie SX, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Van Deerlin VM, Lee VM, Soares H, Trojanowski JQ. Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease. Ann Neurol. 2011 Apr; 69(4):655-63. PMID: 21520231; PMCID: PMC3155276.
  130. Womack KB, Diaz-Arrastia R, Aizenstein HJ, Arnold SE, Barbas NR, Boeve BF, Clark CM, DeCarli CS, Jagust WJ, Leverenz JB, Peskind ER, Turner RS, Zamrini EY, Heidebrink JL, Burke JR, DeKosky ST, Farlow MR, Gabel MJ, Higdon R, Kawas CH, Koeppe RA, Lipton AM, Foster NL. Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors. Arch Neurol. 2011 Mar; 68(3):329-37. PMID: 21059987; PMCID: PMC3058918.
  131. Hu WT, Chen-Plotkin A, Grossman M, Arnold SE, Clark CM, Shaw LM, McCluskey L, Elman L, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Novel CSF biomarkers for frontotemporal lobar degenerations. Neurology. 2010 Dec 07; 75(23):2079-86. PMID: 21048198; PMCID: PMC2995537.
  132. Buchman AS, Boyle PA, Wilson RS, James BD, Leurgans SE, Arnold SE, Bennett DA. Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study. BMC Geriatr. 2010 Oct 22; 10:77. PMID: 20969786; PMCID: PMC2975650.
  133. Hamilton R, Patel S, Lee EB, Jackson EM, Lopinto J, Arnold SE, Clark CM, Basil A, Shaw LM, Xie SX, Grady MS, Trojanowski JQ. Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology. Ann Neurol. 2010 Oct; 68(4):535-40. PMID: 20687117; PMCID: PMC2964442.
  134. Geser F, Robinson JL, Malunda JA, Xie SX, Clark CM, Kwong LK, Moberg PJ, Moore EM, Van Deerlin VM, Lee VM, Arnold SE, Trojanowski JQ. Pathological 43-kDa transactivation response DNA-binding protein in older adults with and without severe mental illness. Arch Neurol. 2010 Oct; 67(10):1238-50. PMID: 20937952; PMCID: PMC3050578.
  135. Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease. Acta Neuropathol. 2010 Sep; 120(3):385-99. PMID: 20652578; PMCID: PMC2982700.
  136. van Zoest T, Gaaloul N, Singh Y, Ahlers H, Herr W, Seidel ST, Ertmer W, Rasel E, Eckart M, Kajari E, Arnold S, Nandi G, Schleich WP, Walser R, Vogel A, Sengstock K, Bongs K, Lewoczko-Adamczyk W, Schiemangk M, Schuldt T, Peters A, Könemann T, Müntinga H, Lämmerzahl C, Dittus H, Steinmetz T, Hänsch TW, Reichel J. Bose-Einstein condensation in microgravity. Science. 2010 Jun 18; 328(5985):1540-3. PMID: 20558713.
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  137. Soetanto A, Wilson RS, Talbot K, Un A, Schneider JA, Sobiesk M, Kelly J, Leurgans S, Bennett DA, Arnold SE. Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch Gen Psychiatry. 2010 May; 67(5):448-57. PMID: 20439826; PMCID: PMC2926797.
  138. Arnold SE, Lee EB, Moberg PJ, Stutzbach L, Kazi H, Han LY, Lee VM, Trojanowski JQ. Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Ann Neurol. 2010 Apr; 67(4):462-9. PMID: 20437581; PMCID: PMC2864948.
  139. Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, Pickering E, Kuhn M, Chen Y, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment. Acta Neuropathol. 2010 Jun; 119(6):669-78. PMID: 20232070; PMCID: PMC2880811.
  140. Trojanowski JQ, Arnold SE, Karlawish JH, Brunden K, Cary M, Davatzikos C, Detre J, Gaulton G, Grossman M, Hurtig H, Jedrziewski K, McCluskey L, Naylor M, Polsky D, Schellenberg GD, Siderowf A, Shaw LM, Van Deerlin V, Wang LS, Werner R, Xie SX, Lee VM. Design of comprehensive Alzheimer's disease centers to address unmet national needs. Alzheimers Dement. 2010 Mar; 6(2):150-5. PMID: 20298979; PMCID: PMC2842603.
  141. Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafman J, Hodges J, Spillantini MG, Gilman S, Lieberman AP, Kaye JA, Woltjer RL, Bigio EH, Mesulam M, Al-Sarraj S, Troakes C, Rosenberg RN, White CL, Ferrer I, Lladó A, Neumann M, Kretzschmar HA, Hulette CM, Welsh-Bohmer KA, Miller BL, Alzualde A, Lopez de Munain A, McKee AC, Gearing M, Levey AI, Lah JJ, Hardy J, Rohrer JD, Lashley T, Mackenzie IR, Feldman HH, Hamilton RL, Dekosky ST, van der Zee J, Kumar-Singh S, Van Broeckhoven C, Mayeux R, Vonsattel JP, Troncoso JC, Kril JJ, Kwok JB, Halliday GM, Bird TD, Ince PG, Shaw PJ, Cairns NJ, Morris JC, McLean CA, DeCarli C, Ellis WG, Freeman SH, Frosch MP, Growdon JH, Perl DP, Sano M, Bennett DA, Schneider JA, Beach TG, Reiman EM, Woodruff BK, Cummings J, Vinters HV, Miller CA, Chui HC, Alafuzoff I, Hartikainen P, Seilhean D, Galasko D, Masliah E, Cotman CW, Tuñón MT, Martínez MC, Munoz DG, Carroll SL, Marson D, Riederer PF, Bogdanovic N, Schellenberg GD, Hakonarson H, Trojanowski JQ, Lee VM. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet. 2010 Mar; 42(3):234-9. PMID: 20154673.
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  142. Yu CE, Bird TD, Bekris LM, Montine TJ, Leverenz JB, Steinbart E, Galloway NM, Feldman H, Woltjer R, Miller CA, Wood EM, Grossman M, McCluskey L, Clark CM, Neumann M, Danek A, Galasko DR, Arnold SE, Chen-Plotkin A, Karydas A, Miller BL, Trojanowski JQ, Lee VM, Schellenberg GD, Van Deerlin VM. The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Arch Neurol. 2010 Feb; 67(2):161-70. PMID: 20142524; PMCID: PMC2901991.
  143. Tang J, LeGros RP, Louneva N, Yeh L, Cohen JW, Hahn CG, Blake DJ, Arnold SE, Talbot K. Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression. Hum Mol Genet. 2009 Oct 15; 18(20):3851-63. PMID: 19617633; PMCID: PMC2748893.
  144. Xie SX, Ewbank DC, Chittams J, Karlawish JH, Arnold SE, Clark CM. Rate of decline in Alzheimer disease measured by a Dementia Severity Rating Scale. Alzheimer Dis Assoc Disord. 2009 Jul-Sep; 23(3):268-74. PMID: 19812470; PMCID: PMC3014643.
  145. Wilson RS, Arnold SE, Schneider JA, Boyle PA, Buchman AS, Bennett DA. Olfactory impairment in presymptomatic Alzheimer's disease. Ann N Y Acad Sci. 2009 Jul; 1170:730-5. PMID: 19686220; PMCID: PMC2857767.
  146. Ewbank DC, Arnold SE. Cool with plaques and tangles. N Engl J Med. 2009 May 28; 360(22):2357-9. PMID: 19474435.
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  147. Hahn CG, Banerjee A, Macdonald ML, Cho DS, Kamins J, Nie Z, Borgmann-Winter KE, Grosser T, Pizarro A, Ciccimaro E, Arnold SE, Wang HY, Blair IA. The post-synaptic density of human postmortem brain tissues: an experimental study paradigm for neuropsychiatric illnesses. PLoS One. 2009; 4(4):e5251. PMID: 19370153; PMCID: PMC2666803.
  148. Cox MM, Tucker AM, Tang J, Talbot K, Richer DC, Yeh L, Arnold SE. Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background. Genes Brain Behav. 2009 Jun; 8(4):390-7. PMID: 19220483; PMCID: PMC2774142.
  149. Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS, Bennett DA, Trojanowski JQ, Arnold SE. Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. Am J Pathol. 2008 Nov; 173(5):1488-95. PMID: 18818379; PMCID: PMC2570138.
  150. Rossol M, Pierer M, Arnold S, Keysser G, Burkhardt H, Baerwald C, Wagner U. Homozygosity for DNASE2 single nucleotide polymorphisms in the 5'-regulatory region is associated with rheumatoid arthritis. Ann Rheum Dis. 2009 Sep; 68(9):1498-503. PMID: 18812394.
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  151. Turetsky BI, Hahn CG, Arnold SE, Moberg PJ. Olfactory receptor neuron dysfunction in schizophrenia. Neuropsychopharmacology. 2009 Feb; 34(3):767-74. PMID: 18754006; PMCID: PMC3524971.
  152. Fairless AH, Dow HC, Toledo MM, Malkus KA, Edelmann M, Li H, Talbot K, Arnold SE, Abel T, Brodkin ES. Low sociability is associated with reduced size of the corpus callosum in the BALB/cJ inbred mouse strain. Brain Res. 2008 Sep 16; 1230:211-7. PMID: 18662677; PMCID: PMC2629607.
  153. Wilson RS, Arnold SE, Buchman AS, Tang Y, Bennett DA. Odor identification and progression of parkinsonian signs in older persons. Exp Aging Res. 2008 Jul-Sep; 34(3):173-87. PMID: 18568978; PMCID: PMC3142656.
  154. Wilson RS, Arnold SE, Beck TL, Bienias JL, Bennett DA. Change in depressive symptoms during the prodromal phase of Alzheimer disease. Arch Gen Psychiatry. 2008 Apr; 65(4):439-45. PMID: 18391132.
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  155. Wilson RS, Schneider JA, Arnold SE, Bienias JL, Bennett DA. Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. Arch Gen Psychiatry. 2007 Oct; 64(10):1204-12. PMID: 17909133.
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  156. Foster NL, Heidebrink JL, Clark CM, Jagust WJ, Arnold SE, Barbas NR, DeCarli CS, Turner RS, Koeppe RA, Higdon R, Minoshima S. FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease. Brain. 2007 Oct; 130(Pt 10):2616-35. PMID: 17704526.
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  157. Nakashima-Yasuda H, Uryu K, Robinson J, Xie SX, Hurtig H, Duda JE, Arnold SE, Siderowf A, Grossman M, Leverenz JB, Woltjer R, Lopez OL, Hamilton R, Tsuang DW, Galasko D, Masliah E, Kaye J, Clark CM, Montine TJ, Lee VM, Trojanowski JQ. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathol. 2007 Sep; 114(3):221-9. PMID: 17653732.
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  158. Xie SX, Forman MS, Farmer J, Moore P, Wang Y, Wang X, Clark CM, Coslett HB, Chatterjee A, Arnold SE, Rosen H, Karlawish JH, Van Deerlin VM, Lee VM, Trojanowski JQ, Grossman M. Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry. 2008 Feb; 79(2):126-9. PMID: 17615171.
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  159. Wilson RS, Schneider JA, Arnold SE, Tang Y, Boyle PA, Bennett DA. Olfactory identification and incidence of mild cognitive impairment in older age. Arch Gen Psychiatry. 2007 Jul; 64(7):802-8. PMID: 17606814.
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  160. Wilson RS, Schneider JA, Boyle PA, Arnold SE, Tang Y, Bennett DA. Chronic distress and incidence of mild cognitive impairment. Neurology. 2007 Jun 12; 68(24):2085-92. PMID: 17562829.
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  161. Gur RC, Turetsky BI, Loughead J, Waxman J, Snyder W, Ragland JD, Elliott MA, Bilker WB, Arnold SE, Gur RE. Hemodynamic responses in neural circuitries for detection of visual target and novelty: An event-related fMRI study. Hum Brain Mapp. 2007 Apr; 28(4):263-74. PMID: 17133387.
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  162. Gur RE, Turetsky BI, Loughead J, Snyder W, Kohler C, Elliott M, Pratiwadi R, Ragland JD, Bilker WB, Siegel SJ, Kanes SJ, Arnold SE, Gur RC. Visual attention circuitry in schizophrenia investigated with oddball event-related functional magnetic resonance imaging. Am J Psychiatry. 2007 Mar; 164(3):442-9. PMID: 17329469.
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  163. Wilson RS, Krueger KR, Arnold SE, Schneider JA, Kelly JF, Barnes LL, Tang Y, Bennett DA. Loneliness and risk of Alzheimer disease. Arch Gen Psychiatry. 2007 Feb; 64(2):234-40. PMID: 17283291.
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  164. Wilson RS, Arnold SE, Schneider JA, Li Y, Bennett DA. Chronic distress, age-related neuropathology, and late-life dementia. Psychosom Med. 2007 Jan; 69(1):47-53. PMID: 17244848.
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  165. Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, Forman MS, Van Deerlin V, de Silva R, Hardy J. The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts. Neurobiol Dis. 2007 Mar; 25(3):561-70. PMID: 17174556.
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  166. Arvanitakis Z, Schneider JA, Wilson RS, Li Y, Arnold SE, Wang Z, Bennett DA. Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology. 2006 Dec 12; 67(11):1960-5. PMID: 17159101.
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  167. O'Connor JA, Muly EC, Arnold SE, Hemby SE. AMPA receptor subunit and splice variant expression in the DLPFC of schizophrenic subjects and rhesus monkeys chronically administered antipsychotic drugs. Schizophr Res. 2007 Feb; 90(1-3):28-40. PMID: 17141476; PMCID: PMC1868481.
  168. Moberg PJ, Arnold SE, Doty RL, Gur RE, Balderston CC, Roalf DR, Gur RC, Kohler CG, Kanes SJ, Siegel SJ, Turetsky BI. Olfactory functioning in schizophrenia: relationship to clinical, neuropsychological, and volumetric MRI measures. J Clin Exp Neuropsychol. 2006 Nov; 28(8):1444-61. PMID: 17050269.
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  169. Wilson RS, Arnold SE, Schneider JA, Tang Y, Bennett DA. The relationship between cerebral Alzheimer's disease pathology and odour identification in old age. J Neurol Neurosurg Psychiatry. 2007 Jan; 78(1):30-5. PMID: 17012338; PMCID: PMC2117790.
  170. Talbot K, Cho DS, Ong WY, Benson MA, Han LY, Kazi HA, Kamins J, Hahn CG, Blake DJ, Arnold SE. Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin. Hum Mol Genet. 2006 Oct 15; 15(20):3041-54. PMID: 16980328.
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  171. Wilson RS, Arnold SE, Schneider JA, Kelly JF, Tang Y, Bennett DA. Chronic psychological distress and risk of Alzheimer's disease in old age. Neuroepidemiology. 2006; 27(3):143-53. PMID: 16974109.
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  172. Lohoff FW, Dahl JP, Ferraro TN, Arnold SE, Gallinat J, Sander T, Berrettini WH. Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar i disorder. Neuropsychopharmacology. 2006 Dec; 31(12):2739-47. PMID: 16936705; PMCID: PMC2507868.
  173. Lindner D, Trantakis C, Renner C, Arnold S, Schmitgen A, Schneider J, Meixensberger J. Application of intraoperative 3D ultrasound during navigated tumor resection. Minim Invasive Neurosurg. 2006 Aug; 49(4):197-202. PMID: 17041829.
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  174. Wilson RS, Buchman AS, Arnold SE, Shah RC, Tang Y, Bennett DA. Harm avoidance and disability in old age. Exp Aging Res. 2006 Jul-Sep; 32(3):243-61. PMID: 16754467.
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  175. Hahn CG, Wang HY, Cho DS, Talbot K, Gur RE, Berrettini WH, Bakshi K, Kamins J, Borgmann-Winter KE, Siegel SJ, Gallop RJ, Arnold SE. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med. 2006 Jul; 12(7):824-8. PMID: 16767099.
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  176. Forman MS, Farmer J, Johnson JK, Clark CM, Arnold SE, Coslett HB, Chatterjee A, Hurtig HI, Karlawish JH, Rosen HJ, Van Deerlin V, Lee VM, Miller BL, Trojanowski JQ, Grossman M. Frontotemporal dementia: clinicopathological correlations. Ann Neurol. 2006 Jun; 59(6):952-62. PMID: 16718704; PMCID: PMC2629792.
  177. Bennett DA, Schneider JA, Tang Y, Arnold SE, Wilson RS. The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study. Lancet Neurol. 2006 May; 5(5):406-12. PMID: 16632311.
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  178. Wilson RS, Krueger KR, Arnold SE, Barnes LL, Mendes de Leon CF, Bienias JL, Bennett DA. Childhood adversity and psychosocial adjustment in old age. Am J Geriatr Psychiatry. 2006 Apr; 14(4):307-15. PMID: 16582039; PMCID: PMC2740729.
  179. Moberg PJ, Arnold SE, Roalf DR, Balderston CC, Abbazia J, Kohler CG, Gur RE, Turetsky BI. Apolipoprotein E genotype and odor identification in schizophrenia. J Neuropsychiatry Clin Neurosci. 2006; 18(2):231-3. PMID: 16720801.
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  180. Wilson RS, Arnold SE, Tang Y, Bennett DA. Odor identification and decline in different cognitive domains in old age. Neuroepidemiology. 2006; 26(2):61-7. PMID: 16352908.
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  181. Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE. Education modifies the association of amyloid but not tangles with cognitive function. Neurology. 2005 Sep 27; 65(6):953-5. PMID: 16186546.
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  182. Rioux L, Gelber EI, Parand L, Kazi HA, Yeh J, Wintering R, Bilker W, Arnold SE. Characterization of olfactory bulb glomeruli in schizophrenia. Schizophr Res. 2005 Sep 15; 77(2-3):229-39. PMID: 15946825.
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  183. Bennett DA, Schneider JA, Wilson RS, Bienias JL, Berry-Kravis E, Arnold SE. Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people. J Neurol Neurosurg Psychiatry. 2005 Sep; 76(9):1194-9. PMID: 16107349; PMCID: PMC1739810.
  184. Sunderland T, Gur RE, Arnold SE. The use of biomarkers in the elderly: current and future challenges. Biol Psychiatry. 2005 Aug 15; 58(4):272-6. PMID: 16018985.
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  185. Bodner SM, Berrettini W, van Deerlin V, Bennett DA, Wilson RS, Trojanowski JQ, Arnold SE. Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 05; 134B(1):1-5. PMID: 15635706.
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  186. Hahn CG, Han LY, Rawson NE, Mirza N, Borgmann-Winter K, Lenox RH, Arnold SE. In vivo and in vitro neurogenesis in human olfactory epithelium. J Comp Neurol. 2005 Mar 07; 483(2):154-63. PMID: 15678478.
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  187. Francis PT, Nordberg A, Arnold SE. A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease? Trends Pharmacol Sci. 2005 Feb; 26(2):104-11. PMID: 15681028.
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  188. Rioux L, Arnold SE. The expression of retinoic acid receptor alpha is increased in the granule cells of the dentate gyrus in schizophrenia. Psychiatry Res. 2005 Jan 30; 133(1):13-21. PMID: 15698673.
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  189. Arnold SE, Talbot K, Hahn CG. Neurodevelopment, neuroplasticity, and new genes for schizophrenia. Prog Brain Res. 2005; 147:319-45. PMID: 15581715.
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  190. Cairns NJ, Grossman M, Arnold SE, Burn DJ, Jaros E, Perry RH, Duyckaerts C, Stankoff B, Pillon B, Skullerud K, Cruz-Sanchez FF, Bigio EH, Mackenzie IR, Gearing M, Juncos JL, Glass JD, Yokoo H, Nakazato Y, Mosaheb S, Thorpe JR, Uryu K, Lee VM, Trojanowski JQ. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology. 2004 Oct 26; 63(8):1376-84. PMID: 15505152; PMCID: PMC3516854.
  191. Rioux L, Ruscheinsky D, Arnold SE. Microtubule-associated protein MAP2 expression in olfactory bulb in schizophrenia. Psychiatry Res. 2004 Aug 30; 128(1):1-7. PMID: 15450909.
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  192. Cairns NJ, Uryu K, Bigio EH, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Arnold SE, Lee VM, Trojanowski JQ. alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases. Acta Neuropathol. 2004 Sep; 108(3):213-23. PMID: 15170578; PMCID: PMC3516855.
  193. Talbot K, Eidem WL, Tinsley CL, Benson MA, Thompson EW, Smith RJ, Hahn CG, Siegel SJ, Trojanowski JQ, Gur RE, Blake DJ, Arnold SE. Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. J Clin Invest. 2004 May; 113(9):1353-63. PMID: 15124027; PMCID: PMC398430.
  194. Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE. Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol. 2004 Mar; 61(3):378-84. PMID: 15023815.
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  195. Arnold SE. Bedside to bench and back again: translational neuroscience research and geriatric psychiatry. Am J Geriatr Psychiatry. 2004 Mar-Apr; 12(2):122-5. PMID: 15010339.
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  196. Nishioka N, Arnold SE. Evidence for oxidative DNA damage in the hippocampus of elderly patients with chronic schizophrenia. Am J Geriatr Psychiatry. 2004 Mar-Apr; 12(2):167-75. PMID: 15010346.
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  197. Bennett DA, Wilson RS, Schneider JA, Bienias JL, Arnold SE. Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older persons. Am J Geriatr Psychiatry. 2004 Mar-Apr; 12(2):211-9. PMID: 15010350.
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  198. Higdon R, Foster NL, Koeppe RA, DeCarli CS, Jagust WJ, Clark CM, Barbas NR, Arnold SE, Turner RS, Heidebrink JL, Minoshima S. A comparison of classification methods for differentiating fronto-temporal dementia from Alzheimer's disease using FDG-PET imaging. Stat Med. 2004 Jan 30; 23(2):315-26. PMID: 14716732.
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  199. Turetsky BI, Moberg PJ, Roalf DR, Arnold SE, Gur RE. Decrements in volume of anterior ventromedial temporal lobe and olfactory dysfunction in schizophrenia. Arch Gen Psychiatry. 2003 Dec; 60(12):1193-200. PMID: 14662551.
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  200. Lowery N, Giovanni L, Mozley LH, Arnold SE, Bilker WB, Gur RE, Moberg PJ. Relationship between clock-drawing and neuropsychological and functional status in elderly institutionalized patients with schizophrenia. Am J Geriatr Psychiatry. 2003 Nov-Dec; 11(6):621-8. PMID: 14609802.
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  201. Feddersen B, Bender A, Arnold S, Klopstock T, Noachtar S. Aggressive confusional state as a clinical manifestation of status epilepticus in MELAS. Neurology. 2003 Oct 28; 61(8):1149-50. PMID: 14581687.
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  202. Wilson RS, Schneider JA, Bienias JL, Arnold SE, Evans DA, Bennett DA. Depressive symptoms, clinical AD, and cortical plaques and tangles in older persons. Neurology. 2003 Oct 28; 61(8):1102-7. PMID: 14581672.
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  203. Moberg PJ, Arnold SE, Doty RL, Kohler C, Kanes S, Seigel S, Gur RE, Turetsky BI. Impairment of odor hedonics in men with schizophrenia. Am J Psychiatry. 2003 Oct; 160(10):1784-9. PMID: 14514491.
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  204. Falke E, Nissanov J, Mitchell TW, Bennett DA, Trojanowski JQ, Arnold SE. Subicular dendritic arborization in Alzheimer's disease correlates with neurofibrillary tangle density. Am J Pathol. 2003 Oct; 163(4):1615-21. PMID: 14507668; PMCID: PMC1868320.
  205. Ernst T, Chang L, Arnold S. Increased glial metabolites predict increased working memory network activation in HIV brain injury. Neuroimage. 2003 Aug; 19(4):1686-93. PMID: 12948723.
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  206. Bennett DA, Wilson RS, Schneider JA, Evans DA, Mendes de Leon CF, Arnold SE, Barnes LL, Bienias JL. Education modifies the relation of AD pathology to level of cognitive function in older persons. Neurology. 2003 Jun 24; 60(12):1909-15. PMID: 12821732.
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  207. Schneider JA, Wilson RS, Cochran EJ, Bienias JL, Arnold SE, Evans DA, Bennett DA. Relation of cerebral infarctions to dementia and cognitive function in older persons. Neurology. 2003 Apr 08; 60(7):1082-8. PMID: 12682310.
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  208. Turetsky BI, Moberg PJ, Arnold SE, Doty RL, Gur RE. Low olfactory bulb volume in first-degree relatives of patients with schizophrenia. Am J Psychiatry. 2003 Apr; 160(4):703-8. PMID: 12668359.
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  209. Bennett DA, Wilson RS, Schneider JA, Evans DA, Aggarwal NT, Arnold SE, Cochran EJ, Berry-Kravis E, Bienias JL. Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease. Neurology. 2003 Jan 28; 60(2):246-52. PMID: 12552039.
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  210. Rioux L, Nissanov J, Lauber K, Bilker WB, Arnold SE. Distribution of microtubule-associated protein MAP2-immunoreactive interstitial neurons in the parahippocampal white matter in subjects with schizophrenia. Am J Psychiatry. 2003 Jan; 160(1):149-55. PMID: 12505814.
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  211. Ernst T, Chang L, Jovicich J, Ames N, Arnold S. Abnormal brain activation on functional MRI in cognitively asymptomatic HIV patients. Neurology. 2002 Nov 12; 59(9):1343-9. PMID: 12427881.
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  212. Kapfhamer D, Valladares O, Sun Y, Nolan PM, Rux JJ, Arnold SE, Veasey SC, Bucan M. Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse. Nat Genet. 2002 Oct; 32(2):290-5. PMID: 12244319.
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  213. Wilson RS, Barnes LL, Mendes de Leon CF, Aggarwal NT, Schneider JS, Bach J, Pilat J, Beckett LA, Arnold SE, Evans DA, Bennett DA. Depressive symptoms, cognitive decline, and risk of AD in older persons. Neurology. 2002 Aug 13; 59(3):364-70. PMID: 12177369.
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  214. Hemby SE, Ginsberg SD, Brunk B, Arnold SE, Trojanowski JQ, Eberwine JH. Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. Arch Gen Psychiatry. 2002 Jul; 59(7):631-40. PMID: 12090816.
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  215. McBride T, Moberg PJ, Arnold SE, Mozley LH, Mahr RN, Gibney M, Kumar A, Gur RE. Neuropsychological functioning in elderly patients with schizophrenia and Alzheimer's disease. Schizophr Res. 2002 Jun 01; 55(3):217-27. PMID: 12048145.
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  216. Spreer J, Arnold S, Quiske A, Wohlfarth R, Ziyeh S, Altenmüller D, Herpers M, Kassubek J, Klisch J, Steinhoff BJ, Honegger J, Schulze-Bonhage A, Schumacher M. Determination of hemisphere dominance for language: comparison of frontal and temporal fMRI activation with intracarotid amytal testing. Neuroradiology. 2002 Jun; 44(6):467-74. PMID: 12070719.
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  217. Mitchell TW, Mufson EJ, Schneider JA, Cochran EJ, Nissanov J, Han LY, Bienias JL, Lee VM, Trojanowski JQ, Bennett DA, Arnold SE. Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease. Ann Neurol. 2002 Feb; 51(2):182-9. PMID: 11835374.
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  218. Arnold SE, Han LY, Moberg PJ, Turetsky BI, Gur RE, Trojanowski JQ, Hahn CG. Dysregulation of olfactory receptor neuron lineage in schizophrenia. Arch Gen Psychiatry. 2001 Sep; 58(9):829-35. PMID: 11545665.
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  219. Spreer J, Quiske A, Altenmüller DM, Arnold S, Schulze-Bonhage A, Steinhoff BJ, Schumacher M. Unsuspected atypical hemispheric dominance for language as determined by fMRI. Epilepsia. 2001 Jul; 42(7):957-9. PMID: 11488901.
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  220. Sharma A, Mani S, Hanna N, Guha C, Vikram B, Weichselbaum RR, Sparano J, Sood B, Lee D, Regine W, Muhodin M, Valentino J, Herman J, Desimone P, Arnold S, Carrico J, Rockich AK, Warner-Carpenter J, Barton-Baxter M. Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors. Hum Gene Ther. 2001 Jun 10; 12(9):1109-31. PMID: 11399232.
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  221. Kurtz MM, Moberg PJ, Mozley LH, Hickey T, Arnold SE, Bilker WB, Gur RE. Cognitive impairment and functional status in elderly institutionalized patients with schizophrenia. Int J Geriatr Psychiatry. 2001 Jun; 16(6):631-8. PMID: 11424173.
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  222. Klisch J, Juengling F, Spreer J, Koch D, Thiel T, Büchert M, Arnold S, Feuerhake F, Schumacher M. Lhermitte-Duclos disease: assessment with MR imaging, positron emission tomography, single-photon emission CT, and MR spectroscopy. AJNR Am J Neuroradiol. 2001 May; 22(5):824-30. PMID: 11337322.
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  223. Kaltenhäuser S, Wagner U, Schuster E, Wassmuth R, Arnold S, Seidel W, Tröltzsch M, Loeffler M, Häntzschel H. Immunogenetic markers and seropositivity predict radiological progression in early rheumatoid arthritis independent of disease activity. J Rheumatol. 2001 Apr; 28(4):735-44. PMID: 11327243.
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  224. Shinnar S, Rapin I, Arnold S, Tuchman RF, Shulman L, Ballaban-Gil K, Maw M, Deuel RK, Volkmar FR. Language regression in childhood. Pediatr Neurol. 2001 Mar; 24(3):183-9. PMID: 11301218.
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  225. Arnold SE. Contributions of neuropathology to understanding schizophrenia in late life. Harv Rev Psychiatry. 2001 Mar-Apr; 9(2):69-76. PMID: 11266404.
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  226. Weil S, Noachtar S, Arnold S, Yousry TA, Winkler PA, Tatsch K. Ictal ECD-SPECT differentiates between temporal and extratemporal epilepsy: confirmation by excellent postoperative seizure control. Nucl Med Commun. 2001 Feb; 22(2):233-7. PMID: 11258411.
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  227. Zhukareva V, Vogelsberg-Ragaglia V, Van Deerlin VM, Bruce J, Shuck T, Grossman M, Clark CM, Arnold SE, Masliah E, Galasko D, Trojanowski JQ, Lee VM. Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Ann Neurol. 2001 Feb; 49(2):165-75. PMID: 11220736.
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  228. Arnold SE, Rioux L. Challenges, status, and opportunities for studying developmental neuropathology in adult schizophrenia. Schizophr Bull. 2001; 27(3):395-416. PMID: 11596843.
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  229. Mitchell TW, Nissanov J, Han LY, Mufson EJ, Schneider JA, Cochran EJ, Bennett DA, Lee VM, Trojanowski JQ, Arnold SE. Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment. J Histochem Cytochem. 2000 Dec; 48(12):1627-38. PMID: 11101631.
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  230. Arnold SE, Han LY, Clark CM, Grossman M, Trojanowski JQ. Quantitative neurohistological features of frontotemporal degeneration. Neurobiol Aging. 2000 Nov-Dec; 21(6):913-9. PMID: 11124442.
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  231. Arnold SE. Part III. Neuropathology of Alzheimer's disease. Dis Mon. 2000 Oct; 46(10):687-705. PMID: 11078010.
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  232. Medina I, Krapivinsky G, Arnold S, Kovoor P, Krapivinsky L, Clapham DE. A switch mechanism for G beta gamma activation of I(KACh). J Biol Chem. 2000 Sep 22; 275(38):29709-16. PMID: 10900209.
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  233. Gur RE, Cowell PE, Latshaw A, Turetsky BI, Grossman RI, Arnold SE, Bilker WB, Gur RC. Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia. Arch Gen Psychiatry. 2000 Aug; 57(8):761-8. PMID: 10920464.
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  234. Gur RE, Turetsky BI, Cowell PE, Finkelman C, Maany V, Grossman RI, Arnold SE, Bilker WB, Gur RC. Temporolimbic volume reductions in schizophrenia. Arch Gen Psychiatry. 2000 Aug; 57(8):769-75. PMID: 10920465.
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  235. Arnold S, Berthele A, Drzezga A, Tölle TR, Weis S, Werhahn KJ, Henkel A, Yousry TA, Winkler PA, Bartenstein P, Noachtar S. Reduction of benzodiazepine receptor binding is related to the seizure onset zone in extratemporal focal cortical dysplasia. Epilepsia. 2000 Jul; 41(7):818-24. PMID: 10897152.
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  236. Arnold SE. Cellular and molecular neuropathology of the parahippocampal region in schizophrenia. Ann N Y Acad Sci. 2000 Jun; 911:275-92. PMID: 10911880.
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  237. Hurtig HI, Trojanowski JQ, Galvin J, Ewbank D, Schmidt ML, Lee VM, Clark CM, Glosser G, Stern MB, Gollomp SM, Arnold SE. Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease. Neurology. 2000 May 23; 54(10):1916-21. PMID: 10822429.
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  238. Turetsky BI, Moberg PJ, Yousem DM, Doty RL, Arnold SE, Gur RE. Reduced olfactory bulb volume in patients with schizophrenia. Am J Psychiatry. 2000 May; 157(5):828-30. PMID: 10784482.
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  239. Shenoy S, Arnold S, Chatila T. Response to steroid therapy in autism secondary to autoimmune lymphoproliferative syndrome. J Pediatr. 2000 May; 136(5):682-7. PMID: 10802504.
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  240. Falke E, Han LY, Arnold SE. Absence of neurodegeneration in the thalamus and caudate of elderly patients with schizophrenia. Psychiatry Res. 2000 Mar 06; 93(2):103-10. PMID: 10725527.
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  241. Dewald G, Stallard R, Alsaadi A, Arnold S, Blough R, Ceperich TM, Rafael Elejalde B, Fink J, Higgins JV, Higgins RR, Hoeltge GA, Hsu WT, Johnson EB, Kronberger D, McCorquodale DJ, Meisner LF, Micale MA, Oseth L, Payne JS, Schwartz S, Sheldon S, Sophian A, Storto P, Van Tuinen P, Wenger GD, Wiktor A, Willis LA, Yung JF, Zenger-Hain J. A multicenter investigation with D-FISH BCR/ABL1 probes. Cancer Genet Cytogenet. 2000 Jan 15; 116(2):97-104. PMID: 10640140.
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  242. Duda JE, Shah U, Arnold SE, Lee VM, Trojanowski JQ. The expression of alpha-, beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases. Exp Neurol. 1999 Dec; 160(2):515-22. PMID: 10619569.
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  243. Winkler PA, Herzog C, Henkel A, Arnold S, Werhahn KJ, Yousry TA, Uttner I, Ilmberger J, Tatsch K, Weis S, Bartenstein P, Noachtar S. [Noninvasive protocol for surgical treatment of focal epilepsies]. Nervenarzt. 1999 Dec; 70(12):1088-93. PMID: 10637814.
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  244. Jokeit H, Ebner A, Arnold S, Schüller M, Antke C, Huang Y, Steinmetz H, Seitz RJ, Witte OW. Bilateral reductions of hippocampal volume, glucose metabolism, and wada hemispheric memory performance are related to the duration of mesial temporal lobe epilepsy. J Neurol. 1999 Oct; 246(10):926-33. PMID: 10552240.
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  245. McBride T, Arnold SE, Gur RC. A comparative volumetric analysis of the prefrontal cortex in human and baboon MRI. Brain Behav Evol. 1999 Sep; 54(3):159-66. PMID: 10559553.
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  246. Azari NP, Knorr U, Arnold S, Antke C, Ebner A, Niemann H, Pettigrew KD, Witte OW, Seitz RJ. Reorganized cerebral metabolic interactions in temporal lobe epilepsy. Neuropsychologia. 1999 Jun; 37(6):625-36. PMID: 10390024.
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  247. Drzezga A, Arnold S, Minoshima S, Noachtar S, Szecsi J, Winkler P, Römer W, Tatsch K, Weber W, Bartenstein P. 18F-FDG PET studies in patients with extratemporal and temporal epilepsy: evaluation of an observer-independent analysis. J Nucl Med. 1999 May; 40(5):737-46. PMID: 10319744.
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  248. Wu RH, Bruening R, Noachtar S, Arnold S, Berchtenbreiter C, Bartenstein P, Drzezga A, Tatsch K, Reiser M. MR measurement of regional relative cerebral blood volume in epilepsy. J Magn Reson Imaging. 1999 Mar; 9(3):435-40. PMID: 10194714.
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  249. Arnold SE. Neurodevelopmental abnormalities in schizophrenia: insights from neuropathology. Dev Psychopathol. 1999; 11(3):439-56. PMID: 10532618.
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  250. Arnold SE, Trojanowski JQ, Parchi P. Protease resistant prion proteins are not present in sporadic "poor outcome" schizophrenia. J Neurol Neurosurg Psychiatry. 1999 Jan; 66(1):90-2. PMID: 9886461; PMCID: PMC1736174.
  251. Arnold SE. Cognition and neuropathology in schizophrenia. Acta Psychiatr Scand Suppl. 1999; 395:41-50. PMID: 10225332.
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  252. Arnold SE, Smutzer GS, Trojanowski JQ, Moberg PJ. Cellular and molecular neuropathology of the olfactory epithelium and central olfactory pathways in Alzheimer's disease and schizophrenia. Ann N Y Acad Sci. 1998 Nov 30; 855:762-75. PMID: 9929682.
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  253. Tran KD, Smutzer GS, Doty RL, Arnold SE. Reduced Purkinje cell size in the cerebellar vermis of elderly patients with schizophrenia. Am J Psychiatry. 1998 Sep; 155(9):1288-90. PMID: 9734558.
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  254. Dewald G, Stallard R, Al Saadi A, Arnold S, Bader PI, Blough R, Chen K, Elejalde BR, Harris CJ, Higgins RR, Hoeltge GA, Hsu WT, Kubic V, McCorquodale DJ, Micale MA, Moore JW, Phillips RM, Scheib-Wixted S, Schwartz S, Siembieda S, Strole K, VanTuinen P, Vance GH, Wiktor A, Zinsmeister A, et al. A multicenter investigation with interphase fluorescence in situ hybridization using X- and Y-chromosome probes. Am J Med Genet. 1998 Apr 01; 76(4):318-26. PMID: 9545096.
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  255. Smutzer G, Lee VM, Trojanowski JQ, Arnold SE. Human olfactory mucosa in schizophrenia. Ann Otol Rhinol Laryngol. 1998 Apr; 107(4):349-55. PMID: 9557772.
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  256. Arnold SE, Trojanowski JQ, Gur RE, Blackwell P, Han LY, Choi C. Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia. Arch Gen Psychiatry. 1998 Mar; 55(3):225-32. PMID: 9510216.
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  257. Arnold SE, Ruscheinsky DD, Han LY. Further evidence of abnormal cytoarchitecture of the entorhinal cortex in schizophrenia using spatial point pattern analyses. Biol Psychiatry. 1997 Oct 15; 42(8):639-47. PMID: 9325556.
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  258. Smutzer G, Zimmerman JE, Han LY, Ruscheinsky DD, Arnold SE, Yu X, Kratskin I. Inositol 1,4,5-trisphosphate receptor expression in odontoblast cells. Biochim Biophys Acta. 1997 Oct 11; 1358(3):221-8. PMID: 9366253.
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  259. Schlaug G, Antke C, Holthausen H, Arnold S, Ebner A, Tuxhorn I, Jäncke L, Lüders H, Witte OW, Seitz RJ. Ictal motor signs and interictal regional cerebral hypometabolism. Neurology. 1997 Aug; 49(2):341-50. PMID: 9270560.
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  260. Moberg PJ, Doty RL, Turetsky BI, Arnold SE, Mahr RN, Gur RC, Bilker W, Gur RE. Olfactory identification deficits in schizophrenia: correlation with duration of illness. Am J Psychiatry. 1997 Jul; 154(7):1016-8. PMID: 9210756.
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  261. Trojanowski JQ, Clark CM, Schmidt ML, Arnold SE, Lee VM. Strategies for improving the postmortem neuropathological diagnosis of Alzheimer's disease. Neurobiol Aging. 1997 Jul-Aug; 18(4 Suppl):S75-9. PMID: 9330990.
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  262. Arnold SE, Joo E, Martinoli MG, Roy N, Trojanowski JQ, Gur RE, Cannon T, Price RA. Apolipoprotein E genotype in schizophrenia: frequency, age of onset, and neuropathologic features. Neuroreport. 1997 Apr 14; 8(6):1523-6. PMID: 9172167.
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  263. Smutzer G, Zimmerman JE, Hahn CG, Ruscheinsky DD, Rodríguez A, Han LY, Arnold SE. Inositol 1,4,5-trisphosphate receptor expression in mammalian olfactory tissue. Brain Res Mol Brain Res. 1997 Mar; 44(2):347-54. PMID: 9073177.
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  264. Buell JF, Reed E, Lee KB, Parker RJ, Venzon DJ, Amikura K, Arnold S, Fraker DL, Alexander HR. Synergistic effect and possible mechanisms of tumor necrosis factor and cisplatin cytotoxicity under moderate hyperthermia against gastric cancer cells. Ann Surg Oncol. 1997 Mar; 4(2):141-8. PMID: 9084851.
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  265. Gurevich EV, Bordelon Y, Shapiro RM, Arnold SE, Gur RE, Joyce JN. Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia. A postmortem study. Arch Gen Psychiatry. 1997 Mar; 54(3):225-32. PMID: 9075463.
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  266. Moberg PJ, Doty RL, Mahr RN, Mesholam RI, Arnold SE, Turetsky BI, Gur RE. Olfactory identification in elderly schizophrenia and Alzheimer's disease. Neurobiol Aging. 1997 Mar-Apr; 18(2):163-7. PMID: 9258893.
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  267. Prohovnik I, Arnold SE, Smith G, Lucas LR. Physostigmine reversal of scopolamine-induced hypofrontality. J Cereb Blood Flow Metab. 1997 Feb; 17(2):220-8. PMID: 9040502.
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  268. Arnold SE. The medial temporal lobe in schizophrenia. J Neuropsychiatry Clin Neurosci. 1997; 9(3):460-70. PMID: 9276847.
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  269. Seitz RJ, Piel S, Arnold S, Schlaug G, Ebner A, Holthausen H, Tuxhorn I, Witte OW. Cerebellar hypometabolism in focal epilepsy is related to age of onset and drug intoxication. Epilepsia. 1996 Dec; 37(12):1194-9. PMID: 8956851.
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  270. Arnold SE, Trojanowski JQ. Recent advances in defining the neuropathology of schizophrenia. Acta Neuropathol. 1996 Sep; 92(3):217-31. PMID: 8870823.
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  271. Arnold S, Schlaug G, Niemann H, Ebner A, Lüders H, Witte OW, Seitz RJ. Topography of interictal glucose hypometabolism in unilateral mesiotemporal epilepsy. Neurology. 1996 May; 46(5):1422-30. PMID: 8628493.
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  272. Arnold SE, Trojanowski JQ. Human fetal hippocampal development: I. Cytoarchitecture, myeloarchitecture, and neuronal morphologic features. J Comp Neurol. 1996 Apr 01; 367(2):274-92. PMID: 8708010.
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  273. Binkofski F, Seitz RJ, Arnold S, Classen J, Benecke R, Freund HJ. Thalamic metbolism and corticospinal tract integrity determine motor recovery in stroke. Ann Neurol. 1996 Apr; 39(4):460-70. PMID: 8619524.
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  274. Arnold SE, Trojanowski JQ. Human fetal hippocampal development: II. The neuronal cytoskeleton. J Comp Neurol. 1996 Apr 01; 367(2):293-307. PMID: 8708011.
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  275. Schlaug G, Hefter H, Engelbrecht V, Kuwert T, Arnold S, Stöcklin G, Seitz RJ. Neurological impairment and recovery in Wilson's disease: evidence from PET and MRI. J Neurol Sci. 1996 Mar; 136(1-2):129-39. PMID: 8815159.
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  276. Arnold SE, Trojanowski JQ. Cognitive impairment in elderly schizophrenia: a dementia (still) lacking distinctive histopathology. Schizophr Bull. 1996; 22(1):5-9. PMID: 8685663.
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  277. Arnold SE, Franz BR, Trojanowski JQ, Moberg PJ, Gur RE. Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia. Acta Neuropathol. 1996; 91(3):269-77. PMID: 8834539.
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  278. Gur RE, Mozley PD, Resnick SM, Mozley LH, Shtasel DL, Gallacher F, Arnold SE, Karp JS, Alavi A, Reivich M, et al. Resting cerebral glucose metabolism in first-episode and previously treated patients with schizophrenia relates to clinical features. Arch Gen Psychiatry. 1995 Aug; 52(8):657-67. PMID: 7632119.
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  279. Arnold SE, Franz BR, Gur RC, Gur RE, Shapiro RM, Moberg PJ, Trojanowski JQ. Smaller neuron size in schizophrenia in hippocampal subfields that mediate cortical-hippocampal interactions. Am J Psychiatry. 1995 May; 152(5):738-48. PMID: 7726314.
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  280. Arnold SE, Gur RE, Shapiro RM, Fisher KR, Moberg PJ, Gibney MR, Gur RC, Blackwell P, Trojanowski JQ. Prospective clinicopathologic studies of schizophrenia: accrual and assessment of patients. Am J Psychiatry. 1995 May; 152(5):731-7. PMID: 7726313.
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  281. Trojanowski JQ, Arnold SE. In pursuit of the molecular neuropathology of schizophrenia. Arch Gen Psychiatry. 1995 Apr; 52(4):274-6; discussion 277-8. PMID: 10681305.
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  282. Gur RC, Mozley LH, Mozley PD, Resnick SM, Karp JS, Alavi A, Arnold SE, Gur RE. Sex differences in regional cerebral glucose metabolism during a resting state. Science. 1995 Jan 27; 267(5197):528-31. PMID: 7824953.
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  283. Martinoli MG, Trojanowski JQ, Schmidt ML, Arnold SE, Fujiwara TM, Lee VM, Hurtig H, Julien JP, Clark C. Association of apolipoprotein epsilon 4 allele and neuropathologic findings in patients with dementia. Acta Neuropathol. 1995; 90(3):239-43. PMID: 8525796.
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  284. Craft S, Park TS, White DA, Schatz J, Noetzel M, Arnold S. Changes in cognitive performance in children with spastic diplegic cerebral palsy following selective dorsal rhizotomy. Pediatr Neurosurg. 1995; 23(2):68-74; discussion 75. PMID: 8555098.
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  285. Holdnack JA, Moberg PJ, Arnold SE, Gur RE, Gur RC. MMPI characteristics in adults diagnosed with ADD: a preliminary report. Int J Neurosci. 1994 Nov; 79(1-2):47-58. PMID: 7744550.
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  286. Houlihan DJ, Flaum M, Arnold SE, Keshavan M, Alliger R. Further evidence for olfactory identification deficits in schizophrenia. Schizophr Res. 1994 May; 12(2):179-82. PMID: 8043528.
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  287. Arnold SE, Franz BR, Trojanowski JQ. Elderly patients with schizophrenia exhibit infrequent neurodegenerative lesions. Neurobiol Aging. 1994 May-Jun; 15(3):299-303. PMID: 7936053.
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  288. Arnold SE, Hyman BT, Van Hoesen GW. Neuropathologic changes of the temporal pole in Alzheimer's disease and Pick's disease. Arch Neurol. 1994 Feb; 51(2):145-50. PMID: 8304839.
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  289. Warner R, Taylor D, Wright J, Sloat A, Springett G, Arnold S, Weinberg H. Substance use among the mentally ill: prevalence, reasons for use, and effects on illness. Am J Orthopsychiatry. 1994 Jan; 64(1):30-9. PMID: 8147425.
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  290. Arnold SE. Estrogen for refractory aggression after traumatic brain injury. Am J Psychiatry. 1993 Oct; 150(10):1564-5. PMID: 8379572.
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  291. Arnold S, Chew DJ, Hubler M, Casal M, Wiestner T, Hogg H, Heckmann R, Powers J, Ruesch P. Reproducibility of urethral pressure profiles in clinically normal sexually intact female dogs by use of microtransducer catheters. Am J Vet Res. 1993 Aug; 54(8):1347-51. PMID: 8214908.
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  292. Arnold SE, Kumar A. Reversible dementias. Med Clin North Am. 1993 Jan; 77(1):215-30. PMID: 8419719.
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  293. Arnold SE, Lee VM, Gur RE, Trojanowski JQ. Abnormal expression of two microtubule-associated proteins (MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia. Proc Natl Acad Sci U S A. 1991 Dec 01; 88(23):10850-4. PMID: 1961755; PMCID: PMC53029.
  294. Hyman BT, Flory JE, Arnold SE, Van Hoesen GW, Schelper RL, Ghanbari H, Haigler H. Quantitative assessment of ALZ-50 immunoreactivity in Alzheimer's disease. J Geriatr Psychiatry Neurol. 1991 Oct-Dec; 4(4):231-5. PMID: 1789912.
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  295. Arnold SE, Hyman BT, Van Hoesen GW, Damasio AR. Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia. Arch Gen Psychiatry. 1991 Jul; 48(7):625-32. PMID: 2069493.
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  296. Arnold SE, Hyman BT, Flory J, Damasio AR, Van Hoesen GW. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb Cortex. 1991 Jan-Feb; 1(1):103-16. PMID: 1822725.
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  297. Arnold SE, Biller J. Spontaneous cerebral embolism from descending thoracic aortic aneurysm--a case report. Angiology. 1991 Jan; 42(1):69-72. PMID: 1992861.
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  298. Liang C, Doherty JU, Faillace R, Maekawa K, Arnold S, Gavras H, Hood WB. Insulin infusion in conscious dogs. Effects on systemic and coronary hemodynamics, regional blood flows, and plasma catecholamines. J Clin Invest. 1982 Jun; 69(6):1321-36. PMID: 6123523; PMCID: PMC370205.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.