Harvard Catalyst Profiles

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Hong Yong Peh, Ph.D.

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2022 - 2023
Development (Travel) Grant
2020 - 2022
Career Development Grant
2017 - 2020
NUS-Overseas Postdoctoral Fellowship
2015 - 2017
President's Graduate Fellowship

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Brüggemann TR, Carlo T, Krishnamoorthy N, Duvall MG, Abdulnour RE, Nijmeh J, Peh HY, Filippakis H, Croze RH, Goh B, Oh SF, Levy BD. Mouse phospholipid phosphatase 6 regulates dendritic cell cholesterol, macropinocytosis, and allergen sensitization. iScience. 2022 Oct 21; 25(10):105185. PMID: 36238896; PMCID: PMC9550614.
  2. Lam TYW, Nguyen N, Peh HY, Shanmugasundaram M, Chandna R, Tee JH, Ong CB, Hossain MZ, Venugopal S, Zhang T, Xu S, Qiu T, Kong WT, Chakarov S, Srivastava S, Liao W, Kim JS, Teh M, Ginhoux F, Fred Wong WS, Ge R. ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis. Proc Natl Acad Sci U S A. 2022 01 25; 119(4). PMID: 35046017; PMCID: PMC8794848.
    Citations: 2     Fields:    Translation:AnimalsCells
  3. Wang X, Rojas-Quintero J, Zhang D, Nakajima T, Walker KH, Peh HY, Li Y, Fucci QA, Tesfaigzi Y, Owen CA. A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice. Mucosal Immunol. 2021 03; 14(2):342-356. PMID: 32690871; PMCID: PMC8422911.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Tavares LP, Peh HY, Tan WSD, Pahima H, Maffia P, Tiligada E, Levi-Schaffer F. Granulocyte-targeted therapies for airway diseases. Pharmacol Res. 2020 07; 157:104881. PMID: 32380052.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  5. Tan WSD, Liao W, Peh HY, Vila M, Dong J, Shen HM, Wong WSF. Andrographolide simultaneously augments Nrf2 antioxidant defense and facilitates autophagic flux blockade in cigarette smoke-exposed human bronchial epithelial cells. Toxicol Appl Pharmacol. 2018 12 01; 360:120-130. PMID: 30291937.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  6. Dong J, Liao W, Peh HY, Tan WSD, Zhou S, Wong WSF. Ribosomal Protein S3 Gene Silencing Protects Against Cigarette Smoke-Induced Acute Lung Injury. Mol Ther Nucleic Acids. 2018 Sep 07; 12:370-380. PMID: 30195775.
    Citations: 7     
  7. Peh HY, Tan WSD, Chan TK, Pow CW, Foster PS, Wong WSF. Vitamin E isoform ?-tocotrienol protects against emphysema in cigarette smoke-induced COPD. Free Radic Biol Med. 2017 09; 110:332-344. PMID: 28684161.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  8. Chan TK, Tan WSD, Peh HY, Wong WSF. Aeroallergens Induce Reactive Oxygen Species Production and DNA Damage and Dampen Antioxidant Responses in Bronchial Epithelial Cells. J Immunol. 2017 07 01; 199(1):39-47. PMID: 28526682.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  9. Dong J, Liao W, Peh HY, Chan TK, Tan WS, Li L, Yong A, Wong WS. Ribosomal protein S3 gene silencing protects against experimental allergic asthma. Br J Pharmacol. 2017 04; 174(7):540-552. PMID: 28093718.
    Citations: 6     Fields:    Translation:AnimalsCells
  10. Liao W, Dong J, Peh HY, Tan LH, Lim KS, Li L, Wong WF. Oligonucleotide Therapy for Obstructive and Restrictive Respiratory Diseases. Molecules. 2017 Jan 17; 22(1). PMID: 28106744.
    Citations: 9     Fields:    Translation:HumansAnimals
  11. Chan JHS, Chua YL, Peh HY, Jovanovic V, Gascoigne NRJ, Wong WSF, Chew FT, Hanson BJ, Kemeny DM, MacAry PA. Molecular engineering of a therapeutic antibody for Blo t 5-induced allergic asthma. J Allergy Clin Immunol. 2017 05; 139(5):1705-1708.e6. PMID: 27923562.
    Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
  12. Chua YL, Liong KH, Huang CH, Wong HS, Zhou Q, Ler SS, Tang Y, Low CP, Koh HY, Kuo IC, Zhang Y, Wong WS, Peh HY, Lim HY, Ge MQ, Haczku A, Angeli V, MacAry PA, Chua KY, Kemeny DM. Blomia tropicalis-Specific TCR Transgenic Th2 Cells Induce Inducible BALT and Severe Asthma in Mice by an IL-4/IL-13-Dependent Mechanism. J Immunol. 2016 11 15; 197(10):3771-3781. PMID: 27733553; PMCID: PMC8904742.
    Citations: 5     Fields:    Translation:AnimalsCells
  13. Chan TK, Loh XY, Peh HY, Tan WNF, Tan WSD, Li N, Tay IJJ, Wong WSF, Engelward BP. House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs. J Allergy Clin Immunol. 2016 07; 138(1):84-96.e1. PMID: 27157131.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  14. Tan WS, Peh HY, Liao W, Pang CH, Chan TK, Lau SH, Chow VT, Wong WS. Cigarette Smoke-Induced Lung Disease Predisposes to More Severe Infection with Nontypeable Haemophilus influenzae: Protective Effects of Andrographolide. J Nat Prod. 2016 05 27; 79(5):1308-15. PMID: 27104764.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  15. Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo MB, Telcian AG, Del Rosario A, Chang C, Peh HY, Kebadze T, Aniscenko J, Stanciu L, Essilfie-Quaye S, Ito K, Barnes PJ, Elkin SL, Kon OM, Wong WS, Adcock IM, Johnston SL. Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD. Chest. 2016 Jan; 149(1):62-73. PMID: 25790167; PMCID: PMC4700054.
    Citations: 31     Fields:    Translation:HumansCells
  16. Peh HY, Tan WS, Liao W, Wong WS. Vitamin E therapy beyond cancer: Tocopherol versus tocotrienol. Pharmacol Ther. 2016 06; 162:152-69. PMID: 26706242.
    Citations: 75     Fields:    Translation:HumansAnimals
  17. Peh HY, Ho WE, Cheng C, Chan TK, Seow AC, Lim AY, Fong CW, Seng KY, Ong CN, Wong WS. Vitamin E Isoform ?-Tocotrienol Downregulates House Dust Mite-Induced Asthma. J Immunol. 2015 Jul 15; 195(2):437-44. PMID: 26041537.
    Citations: 12     Fields:    Translation:AnimalsCells
  18. Ho WE, Xu YJ, Cheng C, Peh HY, Tannenbaum SR, Wong WSF, Ong CN. Metabolomics Reveals Inflammatory-Linked Pulmonary Metabolic Alterations in a Murine Model of House Dust Mite-Induced Allergic Asthma. J Proteome Res. 2014 Aug 01; 13(8):3771-3782. PMID: 24956233.
    Citations: 10     Fields:    
  19. Ho WE, Peh HY, Chan TK, Wong WS. Artemisinins: pharmacological actions beyond anti-malarial. Pharmacol Ther. 2014 Apr; 142(1):126-39. PMID: 24316259.
    Citations: 123     Fields:    Translation:HumansAnimals
  20. Guan SP, Tee W, Ng DS, Chan TK, Peh HY, Ho WE, Cheng C, Mak JC, Wong WS. Andrographolide protects against cigarette smoke-induced oxidative lung injury via augmentation of Nrf2 activity. Br J Pharmacol. 2013 Apr; 168(7):1707-18. PMID: 23146110; PMCID: PMC3605877.
    Citations: 37     Fields:    Translation:AnimalsCells
  21. Ho WE, Xu YJ, Xu F, Cheng C, Peh HY, Tannenbaum SR, Wong WS, Ong CN. Metabolomics reveals altered metabolic pathways in experimental asthma. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):204-11. PMID: 23144334.
    Citations: 31     Fields:    Translation:Animals
  22. Ho WE, Cheng C, Peh HY, Xu F, Tannenbaum SR, Ong CN, Wong WS. Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma. Free Radic Biol Med. 2012 Aug 01; 53(3):498-507. PMID: 22634146.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.