Harvard Catalyst Profiles

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Yu Hou, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Braun DA, Street K, Burke KP, Cookmeyer DL, Denize T, Pedersen CB, Gohil SH, Schindler N, Pomerance L, Hirsch L, Bakouny Z, Hou Y, Forman J, Huang T, Li S, Cui A, Keskin DB, Steinharter J, Bouchard G, Sun M, Pimenta EM, Xu W, Mahoney KM, McGregor BA, Hirsch MS, Chang SL, Livak KJ, McDermott DF, Shukla SA, Olsen LR, Signoretti S, Sharpe AH, Irizarry RA, Choueiri TK, Wu CJ. Progressive immune dysfunction with advancing disease stage in renal cell carcinoma. Cancer Cell. 2021 05 10; 39(5):632-648.e8. PMID: 33711273.
    Citations: 4     Fields:    
  2. Bakouny Z, Braun DA, Shukla SA, Pan W, Gao X, Hou Y, Flaifel A, Tang S, Bosma-Moody A, He MX, Vokes N, Nyman J, Xie W, Nassar AH, Abou Alaiwi S, Flippot R, Bouchard G, Steinharter JA, Nuzzo PV, Ficial M, Sant'Angelo M, Forman J, Berchuck JE, Dudani S, Bi K, Park J, Camp S, Sticco-Ivins M, Hirsch L, Baca SC, Wind-Rotolo M, Ross-Macdonald P, Sun M, Lee GM, Chang SL, Wei XX, McGregor BA, Harshman LC, Genovese G, Ellis L, Pomerantz M, Hirsch MS, Freedman ML, Atkins MB, Wu CJ, Ho TH, Linehan WM, McDermott DF, Heng DYC, Viswanathan SR, Signoretti S, Van Allen EM, Choueiri TK. Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. Nat Commun. 2021 02 05; 12(1):808. PMID: 33547292.
    Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
  3. Ficial M, Jegede OA, Sant'Angelo M, Hou Y, Flaifel A, Pignon JC, Braun DA, Wind-Rotolo M, Sticco-Ivins MA, Catalano PJ, Freeman GJ, Sharpe AH, Hodi FS, Motzer RJ, Wu CJ, Atkins MB, McDermott DF, Shukla SA, Choueiri TK, Signoretti S. Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma. Clin Cancer Res. 2021 03 01; 27(5):1371-1380. PMID: 33219016.
    Citations: 5     Fields:    
  4. Braun DA, Hou Y, Bakouny Z, Ficial M, Sant' Angelo M, Forman J, Ross-Macdonald P, Berger AC, Jegede OA, Elagina L, Steinharter J, Sun M, Wind-Rotolo M, Pignon JC, Cherniack AD, Lichtenstein L, Neuberg D, Catalano P, Freeman GJ, Sharpe AH, McDermott DF, Van Allen EM, Signoretti S, Wu CJ, Shukla SA, Choueiri TK. Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma. Nat Med. 2020 06; 26(6):909-918. PMID: 32472114.
    Citations: 56     Fields:    Translation:HumansCells
  5. Liu T, Chen CY, Chen-Deng A, Chen YL, Wang JY, Hou YI, Lin MC. Joining Illumina paired-end reads for classifying phylogenetic marker sequences. BMC Bioinformatics. 2020 Mar 14; 21(1):105. PMID: 32171248.
    Citations: 5     Fields:    Translation:HumansCells
  6. Bian S, Hou Y, Zhou X, Li X, Yong J, Wang Y, Wang W, Yan J, Hu B, Guo H, Wang J, Gao S, Mao Y, Dong J, Zhu P, Xiu D, Yan L, Wen L, Qiao J, Tang F, Fu W. Single-cell multiomics sequencing and analyses of human colorectal cancer. Science. 2018 11 30; 362(6418):1060-1063. PMID: 30498128.
    Citations: 58     Fields:    Translation:HumansCells
  7. Ji Q, Zheng Y, Zhang G, Hu Y, Fan X, Hou Y, Wen L, Li L, Xu Y, Wang Y, Tang F. Single-cell RNA-seq analysis reveals the progression of human osteoarthritis. Ann Rheum Dis. 2019 01; 78(1):100-110. PMID: 30026257.
    Citations: 48     Fields:    Translation:HumansCells
  8. Yu L, Li J, Hong J, Takashima Y, Fujimoto N, Nakajima M, Yamamoto A, Dong X, Dang Y, Hou Y, Yang W, Minami I, Okita K, Tanaka M, Luo C, Tang F, Chen Y, Tang C, Kotera H, Liu L. Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells. Stem Cell Reports. 2018 07 10; 11(1):142-156. PMID: 30008324.
    Citations: 8     Fields:    Translation:HumansCells
  9. Yang X, Hu B, Hou Y, Qiao Y, Wang R, Chen Y, Qian Y, Feng S, Chen J, Liu C, Peng G, Tang F, Jing N. Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages. Cell Res. 2018 May; 28(5):593-596. PMID: 29463899.
    Citations: 9     Fields:    Translation:AnimalsCells
  10. Zhu P, Guo H, Ren Y, Hou Y, Dong J, Li R, Lian Y, Fan X, Hu B, Gao Y, Wang X, Wei Y, Liu P, Yan J, Ren X, Yuan P, Yuan Y, Yan Z, Wen L, Yan L, Qiao J, Tang F. Single-cell DNA methylome sequencing of human preimplantation embryos. Nat Genet. 2018 01; 50(1):12-19. PMID: 29255258.
    Citations: 67     Fields:    Translation:HumansCells
  11. Kuo WS, Chen HH, Chen SY, Chang CY, Chen PC, Hou YI, Shao YT, Kao HF, Lilian Hsu CL, Chen YC, Chen SJ, Wu SR, Wang JY. Graphene quantum dots with nitrogen-doped content dependence for highly efficient dual-modality photodynamic antimicrobial therapy and bioimaging. Biomaterials. 2017 03; 120:185-194. PMID: 28063357.
    Citations: 11     Fields:    Translation:Cells
  12. Xiao C, Gao L, Hou Y, Xu C, Chang N, Wang F, Hu K, He A, Luo Y, Wang J, Peng J, Tang F, Zhu X, Xiong JW. Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish. Nat Commun. 2016 12 08; 7:13787. PMID: 27929112.
    Citations: 26     Fields:    Translation:AnimalsCells
  13. Guo H, Hu B, Yan L, Yong J, Wu Y, Gao Y, Guo F, Hou Y, Fan X, Dong J, Wang X, Zhu X, Yan J, Wei Y, Jin H, Zhang W, Wen L, Tang F, Qiao J. DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells. Cell Res. 2017 Feb; 27(2):165-183. PMID: 27824029.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  14. Shi Y, Wu W, Chai Q, Li Q, Hou Y, Xia H, Ren B, Xu H, Guo X, Jin C, Lv M, Wang Z, Fu YX, Zhu M. LTßR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration. Nat Commun. 2016 08 05; 7:12369. PMID: 27493002.
    Citations: 9     Fields:    Translation:AnimalsCells
  15. Wang JY, Chen CA, Hou YI, Hsiao WL, Huang YW, Tsai YT, Tsai HJ. Longitudinal pattern of multiplexed immunoglobulin E sensitization from prenatal stage to the first year of life. Pediatr Allergy Immunol. 2016 09; 27(6):620-6. PMID: 27089848.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  16. Hou Y, Guo H, Cao C, Li X, Hu B, Zhu P, Wu X, Wen L, Tang F, Huang Y, Peng J. Single-cell triple omics sequencing reveals genetic, epigenetic, and transcriptomic heterogeneity in hepatocellular carcinomas. Cell Res. 2016 Mar; 26(3):304-19. PMID: 26902283.
    Citations: 156     Fields:    Translation:HumansAnimalsCells
  17. Guo F, Yan L, Guo H, Li L, Hu B, Zhao Y, Yong J, Hu Y, Wang X, Wei Y, Wang W, Li R, Yan J, Zhi X, Zhang Y, Jin H, Zhang W, Hou Y, Zhu P, Li J, Zhang L, Liu S, Ren Y, Zhu X, Wen L, Gao YQ, Tang F, Qiao J. The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells. Cell. 2015 Jun 04; 161(6):1437-52. PMID: 26046443.
    Citations: 152     Fields:    Translation:HumansCells
  18. Wen L, Li X, Yan L, Tan Y, Li R, Zhao Y, Wang Y, Xie J, Zhang Y, Song C, Yu M, Liu X, Zhu P, Li X, Hou Y, Guo H, Wu X, He C, Li R, Tang F, Qiao J. Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biol. 2014 Mar 04; 15(3):R49. PMID: 24594098.
    Citations: 119     Fields:    Translation:HumansCells
  19. Hou Y, Fan W, Yan L, Li R, Lian Y, Huang J, Li J, Xu L, Tang F, Xie XS, Qiao J. Genome analyses of single human oocytes. Cell. 2013 Dec 19; 155(7):1492-506. PMID: 24360273.
    Citations: 119     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.