Harvard Catalyst Profiles

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Dimitrios Bitounis, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Toprani SM, Bitounis D, Huang Q, Oliveira N, Ng KW, Tay CY, Nagel ZD, Demokritou P. High-Throughput Screening Platform for Nanoparticle-Mediated Alterations of DNA Repair Capacity. ACS Nano. 2021 03 23; 15(3):4728-4746. PMID: 33710878.
    Citations:    Fields:    Translation:HumansCells
  2. Wu Z, Shi P, Lim HK, Ma Y, Setyawati MI, Bitounis D, Demokritou P, Ng KW, Tay CY. Inflammation Increases Susceptibility of Human Small Airway Epithelial Cells to Pneumonic Nanotoxicity. Small. 2020 05; 16(21):e2000963. PMID: 32338442.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  3. Parviz D, Bitounis D, Demokritou P, Strano M. Engineering Two-dimensional Nanomaterials to Enable Structure-Activity Relationship Studies in Nanosafety Research. NanoImpact. 2020 Apr; 18. PMID: 32617436.
    Citations: 3     
  4. O'Connor BB, Grevesse T, Zimmerman JF, Ardoña HAM, Jimenez JA, Bitounis D, Demokritou P, Parker KK. Human brain microvascular endothelial cell pairs model tissue-level blood-brain barrier function. Integr Biol (Camb). 2020 04 14; 12(3):64-79. PMID: 32195539.
    Citations:    Fields:    Translation:HumansCells
  5. Bitounis D, Parviz D, Cao X, Amadei CA, Vecitis CD, Sunderland EM, Thrall BD, Fang M, Strano MS, Demokritou P. Synthesis and Physicochemical Transformations of Size-Sorted Graphene Oxide during Simulated Digestion and Its Toxicological Assessment against an In Vitro Model of the Human Intestinal Epithelium. Small. 2020 05; 16(21):e1907640. PMID: 32196921.
    Citations: 3     Fields:    Translation:Humans
  6. Duan Y, Coreas R, Liu Y, Bitounis D, Zhang Z, Parviz D, Strano M, Demokritou P, Zhong W. Prediction of protein corona on nanomaterials by machine learning using novel descriptors. NanoImpact. 2020 Jan; 17. PMID: 32104746.
    Citations: 4     
  7. Touloumes GJ, Ardoña HAM, Casalino EK, Zimmerman JF, Chantre CO, Bitounis D, Demokritou P, Parker KK. Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues. NanoImpact. 2020 Jan; 17. PMID: 33251378.
    Citations: 1     
  8. Eweje F, Ardoña HAM, Zimmerman JF, O'Connor BB, Ahn S, Grevesse T, Rivera KN, Bitounis D, Demokritou P, Parker KK. Quantifying the effects of engineered nanomaterials on endothelial cell architecture and vascular barrier integrity using a cell pair model. Nanoscale. 2019 Oct 03; 11(38):17878-17893. PMID: 31553035.
    Citations: 7     Fields:    Translation:HumansCells
  9. Cao X, DeLoid GM, Bitounis D, De La Torre-Roche R, White JC, Zhang Z, Ho CG, Ng KW, Eitzer BD, Demokritou P. Co-exposure to the food additives SiO2 (E551) or TiO2 (E171) and the pesticide boscalid increases cytotoxicity and bioavailability of the pesticide in a tri-culture small intestinal epithelium model: Potential health implications. Environ Sci Nano. 2019 Sep 01; 6(9):2786-2800. PMID: 32133147.
    Citations: 12     
  10. Bitounis D, Pyrgiotakis G, Bousfield D, Demokritou P. Dispersion preparation, characterization, and dosimetric analysis of cellulose nano-fibrils and nano-crystals: Implications for cellular toxicological studies. NanoImpact. 2019 Mar; 15. PMID: 32133424.
    Citations: 3     
  11. Salari M, Bitounis D, Bhattacharya K, Pyrgiotakis G, Zhang Z, Purington E, Gramlich W, Grondin Y, Rogers R, Bousfield D, Demokritou P. Development & Characterization of Fluorescently Tagged Nanocellulose for Nanotoxicological Studies. Environ Sci Nano. 2019 May 01; 6(5):1516-1526. PMID: 31844523.
    Citations: 3     
  12. Zhang Z, Zhang R, Xiao H, Bhattacharya K, Bitounis D, Demokritou P, McClements DJ. Development of a standardized food model for studying the impact of food matrix effects on the gastrointestinal fate and toxicity of ingested nanomaterials. NanoImpact. 2019 Jan; 13:13-25. PMID: 31093583.
    Citations: 14     
  13. Bitounis D, Barnier V, Guibert C, Pourchez J, Forest V, Boudard D, Hochepied JF, Chelle P, Vergnon JM, Cottier M. A method for the quantitative extraction of gold nanoparticles from human bronchoalveolar lavage fluids through a glycerol gradient. Nanoscale. 2018 Feb 08; 10(6):2955-2969. PMID: 29372197.
    Citations: 1     Fields:    Translation:Humans
  14. Bitounis D, Klein JP, Mery L, El-Merhie A, Forest V, Boudard D, Pourchez J, Cottier M. Ex vivo detection and quantification of gold nanoparticles in human seminal and follicular fluids. Analyst. 2018 Jan 15; 143(2):475-486. PMID: 29230439.
    Citations:    Fields:    Translation:Humans
  15. Forest V, Vergnon JM, Guibert C, Bitounis D, Leclerc L, Sarry G, Pourchez J. Metal load assessment in patient pulmonary lavages: towards a comprehensive mineralogical analysis including the nano-sized fraction. Nanotoxicology. 2017 Nov - Dec; 11(9-10):1211-1224. PMID: 29172825.
    Citations: 1     Fields:    Translation:Humans
  16. Bitounis D, Pourchez J, Forest V, Boudard D, Cottier M, Klein JP. Detection and analysis of nanoparticles in patients: A critical review of the status quo of clinical nanotoxicology. Biomaterials. 2016 Jan; 76:302-12. PMID: 26561929.
    Citations: 4     Fields:    Translation:Humans
  17. Rinaldi L, Barabino G, Klein JP, Bitounis D, Pourchez J, Forest V, Boudard D, Leclerc L, Sarry G, Roblin X, Cottier M, Phelip JM. Metals distribution in colorectal biopsies: New insight on the elemental fingerprint of tumour tissue. Dig Liver Dis. 2015 Jul; 47(7):602-7. PMID: 25869551.
    Citations:    Fields:    Translation:Humans
  18. Bitounis D, Ali-Boucetta H, Hong BH, Min DH, Kostarelos K. Prospects and challenges of graphene in biomedical applications. . 2013 Apr 24; 25(16):2258-68. PMID: 23494834.
    Citations: 73     Translation:HumansAnimals
  19. Ali-Boucetta H, Bitounis D, Raveendran-Nair R, Servant A, Van den Bossche J, Kostarelos K. Purified graphene oxide dispersions lack in vitro cytotoxicity and in vivo pathogenicity. Adv Healthc Mater. 2013 Mar; 2(3):433-41. PMID: 23184580.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  20. Bitounis D, Fanciullino R, Iliadis A, Ciccolini J. Optimizing Druggability through Liposomal Formulations: New Approaches to an Old Concept. ISRN Pharm. 2012; 2012:738432. PMID: 22474607.
    Citations: 13     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.