Harvard Catalyst Profiles

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Rajula Elango, M.S.

Title
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Biography
education and training
University of Iowa, IowaPhD12/2017Genetics

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Elango R, Panday A, Willis NA, Scully R. Exploiting CRISPR/Cas9 to engineer precise segmental deletions in mouse embryonic stem cells. STAR Protoc. 2022 09 16; 3(3):101551. PMID: 36042887; PMCID: PMC9420392.
    Citations:    Fields:    Translation:AnimalsCells
  2. Elango R, Panday A, Lach FP, Willis NA, Nicholson K, Duffey EE, Smogorzewska A, Scully R. The structure-specific endonuclease complex SLX4-XPF regulates Tus-Ter-induced homologous recombination. Nat Struct Mol Biol. 2022 08; 29(8):801-812. PMID: 35941380; PMCID: PMC9941964.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Panday A, Elango R, Willis NA, Scully R. A modified CUT&RUN-seq technique for qPCR analysis of chromatin-protein interactions. STAR Protoc. 2022 09 16; 3(3):101529. PMID: 35928003; PMCID: PMC9344018.
    Citations:    Fields:    Translation:Cells
  4. Scully R, Elango R, Panday A, Willis NA. Recombination and restart at blocked replication forks. Curr Opin Genet Dev. 2021 12; 71:154-162. PMID: 34464818; PMCID: PMC9006750.
    Citations: 7     Fields:    Translation:Cells
  5. Panday A, Willis NA, Elango R, Menghi F, Duffey EE, Liu ET, Scully R. FANCM regulates repair pathway choice at stalled replication forks. Mol Cell. 2021 06 03; 81(11):2428-2444.e6. PMID: 33882298; PMCID: PMC8180084.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  6. Liu L, Yan Z, Osia BA, Twarowski J, Sun L, Kramara J, Lee RS, Kumar S, Elango R, Li H, Dang W, Ira G, Malkova A. Tracking break-induced replication shows that it stalls at roadblocks. Nature. 2021 02; 590(7847):655-659. PMID: 33473214; PMCID: PMC8219245.
    Citations: 17     Fields:    Translation:AnimalsCells
  7. Osia B, Elango R, Kramara J, Roberts SA, Malkova A. Investigation of Break-Induced Replication in Yeast. Methods Mol Biol. 2021; 2153:307-328. PMID: 32840789; PMCID: PMC9041317.
    Citations:    Fields:    Translation:AnimalsCells
  8. Elango R, Osia B, Harcy V, Malc E, Mieczkowski PA, Roberts SA, Malkova A. Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements. Nucleic Acids Res. 2019 10 10; 47(18):9666-9684. PMID: 31392335; PMCID: PMC6765108.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  9. Scully R, Panday A, Elango R, Willis NA. DNA double-strand break repair-pathway choice in somatic mammalian cells. Nat Rev Mol Cell Biol. 2019 11; 20(11):698-714. PMID: 31263220; PMCID: PMC7315405.
    Citations: 370     Fields:    Translation:HumansAnimalsCells
  10. Klein HL, Bacinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microb Cell. 2019 Jan 07; 6(1):1-64. PMID: 30652105.
    Citations: 19     
  11. Elango R, Kockler Z, Liu L, Malkova A. Investigation of Break-Induced Replication in Yeast. Methods Enzymol. 2018; 601:161-203. PMID: 29523232.
    Citations: 3     Fields:    Translation:AnimalsCells
  12. Elango R, Sheng Z, Jackson J, DeCata J, Ibrahim Y, Pham NT, Liang DH, Sakofsky CJ, Vindigni A, Lobachev KS, Ira G, Malkova A. Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2. Nat Commun. 2017 11 27; 8(1):1790. PMID: 29176630.
    Citations: 35     Fields:    Translation:AnimalsCells
  13. Saini N, Ramakrishnan S, Elango R, Ayyar S, Zhang Y, Deem A, Ira G, Haber JE, Lobachev KS, Malkova A. Migrating bubble during break-induced replication drives conservative DNA synthesis. Nature. 2013 Oct 17; 502(7471):389-92. PMID: 24025772.
    Citations: 201     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.