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Katharina Tepper, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kaniyappan S, Tepper K, Biernat J, Chandupatla RR, Hübschmann S, Irsen S, Bicher S, Klatt C, Mandelkow EM, Mandelkow E. FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments. Mol Neurodegener. 2020 07 16; 15(1):39. PMID: 32677995.
    Citations:    
  2. Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 2019 Jan 16; 101(2):349. PMID: 30653936.
    Citations:    Fields:    
  3. Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. 2018 09 05; 99(5):925-940.e7. PMID: 30189209.
    Citations:    Fields:    
  4. Mari SA, Wegmann S, Tepper K, Hyman BT, Mandelkow EM, Mandelkow E, Müller DJ. Reversible Cation-Selective Attachment and Self-Assembly of Human Tau on Supported Brain Lipid Membranes. Nano Lett. 2018 05 09; 18(5):3271-3281. PMID: 29644863.
    Citations:    Fields:    Translation:HumansCells
  5. Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C, Roe AD, Fan Z, Molliex AM, Hernandez-Vega A, Muller D, Hyman AA, Mandelkow E, Taylor JP, Hyman BT. Tau protein liquid-liquid phase separation can initiate tau aggregation. EMBO J. 2018 04 03; 37(7). PMID: 29472250.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Xiang S, Kulminskaya N, Habenstein B, Biernat J, Tepper K, Paulat M, Griesinger C, Becker S, Lange A, Mandelkow E, Linser R. A Two-Component Adhesive: Tau Fibrils Arise from a Combination of a Well-Defined Motif and Conformationally Flexible Interactions. J Am Chem Soc. 2017 02 22; 139(7):2639-2646. PMID: 28124562.
    Citations:    Fields:    Translation:HumansCells
  7. Wang Y, Balaji V, Kaniyappan S, Krüger L, Irsen S, Tepper K, Chandupatla R, Maetzler W, Schneider A, Mandelkow E, Mandelkow EM. The release and trans-synaptic transmission of Tau via exosomes. Mol Neurodegener. 2017 01 13; 12(1):5. PMID: 28086931.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  8. Akoury E, Mukrasch MD, Biernat J, Tepper K, Ozenne V, Mandelkow E, Blackledge M, Zweckstetter M. Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer. Protein Sci. 2016 May; 25(5):1010-20. PMID: 26940799.
    Citations: 4     Fields:    Translation:HumansCells
  9. Mair W, Muntel J, Tepper K, Tang S, Biernat J, Seeley WW, Kosik KS, Mandelkow E, Steen H, Steen JA. FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease. Anal Chem. 2016 Apr 05; 88(7):3704-14. PMID: 26877193.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  10. Kadavath H, Hofele RV, Biernat J, Kumar S, Tepper K, Urlaub H, Mandelkow E, Zweckstetter M. Tau stabilizes microtubules by binding at the interface between tubulin heterodimers. Proc Natl Acad Sci U S A. 2015 Jun 16; 112(24):7501-6. PMID: 26034266.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  11. Tepper K, Biernat J, Kumar S, Wegmann S, Timm T, Hübschmann S, Redecke L, Mandelkow EM, Müller DJ, Mandelkow E. Oligomer formation of tau protein hyperphosphorylated in cells. J Biol Chem. 2014 Dec 05; 289(49):34389-407. PMID: 25339173.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  12. Kumar S, Tepper K, Kaniyappan S, Biernat J, Wegmann S, Mandelkow EM, Müller DJ, Mandelkow E. Stages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicity. J Biol Chem. 2014 Jul 18; 289(29):20318-32. PMID: 24825901.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  13. Daebel V, Chinnathambi S, Biernat J, Schwalbe M, Habenstein B, Loquet A, Akoury E, Tepper K, Müller H, Baldus M, Griesinger C, Zweckstetter M, Mandelkow E, Vijayan V, Lange A. ß-Sheet core of tau paired helical filaments revealed by solid-state NMR. J Am Chem Soc. 2012 Aug 29; 134(34):13982-9. PMID: 22862303.
    Citations: 37     Fields:    Translation:HumansCells
  14. Garvey M, Tepper K, Haupt C, Knüpfer U, Klement K, Meinhardt J, Horn U, Balbach J, Fändrich M. Phosphate and HEPES buffers potently affect the fibrillation and oligomerization mechanism of Alzheimer's Aß peptide. Biochem Biophys Res Commun. 2011 Jun 10; 409(3):385-8. PMID: 21575606.
    Citations: 2     Fields:    Translation:Humans
  15. Friedrich RP, Tepper K, Rönicke R, Soom M, Westermann M, Reymann K, Kaether C, Fändrich M. Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):1942-7. PMID: 20133839.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  16. Balk J, Aguilar Netz DJ, Tepper K, Pierik AJ, Lill R. The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly. Mol Cell Biol. 2005 Dec; 25(24):10833-41. PMID: 16314508.
    Citations: 44     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.