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Paige L. Williams, Ph.D.

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Overview
As a faculty member with joint appointments in both Biostatistics and Epidemiology, I have focused my research over the last 25 years on environmental epidemiology studies and on HIV-related clinical trials and observational studies, with a common focus on reproductive outcomes and child development. A major focus of my HIV-related research is the safety evaluation of reproductive health outcomes in infants exposed in utero to antiretroviral agents, such as congenital anomalies, preterm birth, and low birth weight, in addition to longer term outcomes such as cardiotoxicity, neurodevelopment and behavioral functioning. My other active area of research is reproductive epidemiology in relation to environmental, nutritional, and other prenatal exposures. I have particular interest in birth and reproductive outcomes associated with prenatal exposures to endocrine disrupting chemicals (EDCs), such as phthalates, dioxins, pesticides, and heavy metals such as lead.

My statistical interests are broad and include mediation analysis, survival outcomes, clustered data, and statistical methods for evaluation of mixtures. I mentor many doctoral and masters students in biostatistics and epidemiology, and also mentor other research staff through my involvement in many collaborative studies.

Learn more about my research interests.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03HD092138 (WILLIAMS, PAIGE L) May 22, 2017 - Apr 30, 2019
    NIH
    Creation of Public Use Datasets for the Pediatric HIV/AIDS Cohort Study
    Role: Principal Investigator
  2. R29ES007981 (WILLIAMS, PAIGE L) Jul 1, 1996 - Jun 30, 2002
    NIH
    STATISTICAL PROBLEMS IN BIOASSAY AND RISK ASSESSMENT
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wesselink AK, Claus Henn B, Fruh V, Orta OR, Weuve J, Hauser R, Williams PL, McClean MD, Sjodin A, Bethea TN, Brasky TM, Baird DD, Wise LA. A Prospective Ultrasound Study of Plasma Polychlorinated Biphenyl Concentrations and Incidence of Uterine Leiomyomata. Epidemiology. 2021 Mar 01; 32(2):259-267. PMID: 33427764.
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  2. Shiau S, Brummel SS, Kennedy EM, Hermetz K, Spector SA, Williams PL, Kacanek D, Smith R, Drury SS, Agwu A, Ellis A, Patel K, Seage GR, van Dyke RB, Marsit CJ. Longitudinal changes in epigenetic age in youth with perinatally-acquired HIV and youth who are perinatally HIV-exposed uninfected. AIDS. 2021 Feb 09. PMID: 33587437.
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  3. Dirajlal-Fargo S, Williams PL, Broadwell C, McFARLAND EJ, Powis KM, Jacobson DL, Jao J. Youth living with perinatally-acquired HIV have lower physical activity levels as they age compared to HIV-exposed uninfected youth. J Acquir Immune Defic Syndr. 2021 Jan 13. PMID: 33443964.
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  4. Rawat P, Brummel SS, Singh KK, Kim J, Frazer KA, Nichols S, Seage Iii GR, Williams PL, Van Dyke RB, Harismendy O, Trout RN, Spector SA. Genomics Links Inflammation with Neurocognitive Impairment in Children Living with Human Immunodeficiency Virus type-1. J Infect Dis. 2020 Dec 29. PMID: 33373444.
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  5. Tyagi P, James-Todd T, Mínguez-Alarcón L, Ford JB, Keller M, Petrozza J, Calafat AM, Hauser R, Williams PL, Bellavia A. Identifying windows of susceptibility to endocrine disrupting chemicals in relation to gestational weight gain among pregnant women attending a fertility clinic. Environ Res. 2020 Dec 25; 194:110638. PMID: 33359703.
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  6. Fruh V, Claus Henn B, Weuve J, Wesselink AK, Orta OR, Heeren T, Hauser R, Calafat AM, Williams PL, Baird DD, Wise LA. Incidence of uterine leiomyoma in relation to urinary concentrations of phthalate and phthalate alternative biomarkers: A prospective ultrasound study. Environ Int. 2021 Feb; 147:106218. PMID: 33360166.
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