Harvard Catalyst Profiles

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Robert Simon Magin, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Schauer NJ, Liu X, Magin RS, Doherty LM, Chan WC, Ficarro SB, Hu W, Roberts RM, Iacob RE, Stolte B, Giacomelli AO, Perera S, McKay K, Boswell SA, Weisberg EL, Ray A, Chauhan D, Dhe-Paganon S, Anderson KC, Griffin JD, Li J, Hahn WC, Sorger PK, Engen JR, Stegmaier K, Marto JA, Buhrlage SJ. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Sci Rep. 2020 Mar 24; 10(1):5324. PMID: 32210275.
  2. Yang J, Meng C, Weisberg E, Case A, Lamberto I, Magin RS, Adamia S, Wang J, Gray N, Liu S, Stone R, Sattler M, Buhrlage S, Griffin JD. Inhibition of the deubiquitinase USP10 induces degradation of SYK. Br J Cancer. 2020 Apr; 122(8):1175-1184. PMID: 32015510.
  3. Schauer NJ, Magin RS, Liu X, Doherty LM, Buhrlage SJ. Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors. J Med Chem. 2020 Mar 26; 63(6):2731-2750. PMID: 31682427.
  4. Deng S, Magin RS, Wei X, Pan B, Petersson EJ, Marmorstein R. Structure and Mechanism of Acetylation by the N-Terminal Dual Enzyme NatA/Naa50 Complex. Structure. 2019 07 02; 27(7):1057-1070.e4. PMID: 31155310.
  5. Magin RS, Doherty LM, Buhrlage SJ. Discovery of a First-In-Class Covalent Allosteric Inhibitor of SUMO E1 Activating Enzyme. Cell Chem Biol. 2019 02 21; 26(2):153-155. PMID: 30794786.
  6. Goris M, Magin RS, Foyn H, Myklebust LM, Varland S, Ree R, Drazic A, Bhambra P, Støve SI, Baumann M, Haug BE, Marmorstein R, Arnesen T. Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4405-4410. PMID: 29581307.
    Citations: 4     Fields:    Translation:HumansAnimals
  7. Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA. Characterization of histone acylations links chromatin modifications with metabolism. Nat Commun. 2017 10 26; 8(1):1141. PMID: 29070843.
    Citations: 4     Fields:    
  8. Magin RS, Deng S, Zhang H, Cooperman B, Marmorstein R. Probing the interaction between NatA and the ribosome for co-translational protein acetylation. PLoS One. 2017; 12(10):e0186278. PMID: 29016658.
    Citations: 3     Fields:    Translation:AnimalsCells
  9. Rong Z, Ouyang Z, Magin RS, Marmorstein R, Yu H. Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. J Biol Chem. 2016 09 02; 291(36):19079-91. PMID: 27422821.
    Citations: 2     Fields:    Translation:HumansCells
  10. Støve SI, Magin RS, Foyn H, Haug BE, Marmorstein R, Arnesen T. Crystal Structure of the Golgi-Associated Human Na-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation. Structure. 2016 07 06; 24(7):1044-56. PMID: 27320834.
    Citations: 7     Fields:    Translation:HumansCells
  11. Magin RS, March ZM, Marmorstein R. The N-terminal Acetyltransferase Naa10/ARD1 Does Not Acetylate Lysine Residues. J Biol Chem. 2016 Mar 04; 291(10):5270-7. PMID: 26755727.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  12. Magin RS, Liszczak GP, Marmorstein R. The molecular basis for histone H4- and H2A-specific amino-terminal acetylation by NatD. Structure. 2015 Feb 03; 23(2):332-41. PMID: 25619998.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.