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Theodorus Van Den Broek, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. van der Poel CE, Bajic G, Macaulay CW, van den Broek T, Ellson CD, Bouma G, Victora GD, Degn SE, Carroll MC. Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through Fc?RIIB. Cell Rep. 2019 11 26; 29(9):2745-2755.e4. PMID: 31775042.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  2. van den Broek T, Janssen NG, Hetem DJ, Bekers W, Kamst M, Fluit AC, van Ingen J, Kusters JG, Rentenaar RJ. INNO-LiPA DNA line probe assay misidentification of M. smegmatis as Mycobacterium fortuitum complex. Diagn Microbiol Infect Dis. 2019 Nov; 95(3):114858. PMID: 31358343.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  3. van den Broek T, Borghans JAM, van Wijk F. The full spectrum of human naive T cells. Nat Rev Immunol. 2018 06; 18(6):363-373. PMID: 29520044.
    Citations: 49     Fields:    Translation:HumansCells
  4. van den Broek T, Madi A, Delemarre EM, Schadenberg AWL, Tesselaar K, Borghans JAM, Nierkens S, Redegeld FA, Otten HG, Rossetti M, Albani S, Sorek R, Cohen IR, Jansen NJG, van Wijk F. Human neonatal thymectomy induces altered B-cell responses and autoreactivity. Eur J Immunol. 2017 11; 47(11):1970-1981. PMID: 28691750.
    Citations: 2     Fields:    Translation:HumansCells
  5. Kassa D, Ran L, Jager W, van den Broek T, Jacobi R, Mekonen M, Messele T, Haks MC, Ottenhoff THM, van Baarle D. Discriminative expression of whole blood genes in HIV patients with latent and active TB in Ethiopia. Tuberculosis (Edinb). 2016 09; 100:25-31. PMID: 27553407.
    Citations: 5     Fields:    Translation:Humans
  6. van den Broek T, Delemarre EM, Janssen WJ, Nievelstein RA, Broen JC, Tesselaar K, Borghans JA, Nieuwenhuis EE, Prakken BJ, Mokry M, Jansen NJ, van Wijk F. Neonatal thymectomy reveals differentiation and plasticity within human naive T cells. J Clin Invest. 2016 Mar 01; 126(3):1126-36. PMID: 26901814.
    Citations: 29     Fields:    Translation:HumansCells
  7. Delemarre EM, van den Broek T, Mijnheer G, Meerding J, Wehrens EJ, Olek S, Boes M, van Herwijnen MJ, Broere F, van Royen A, Wulffraat NM, Prakken BJ, Spierings E, van Wijk F. Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells. Blood. 2016 Jan 07; 127(1):91-101. PMID: 26480932.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  8. van den Broek T, Hoppenreijs E, Meerding J, Scholman R, Otten HG, Swart JF, Martini A, Prakken B, de Jager W. Cytokine profiling at disease onset: support for classification of young antinuclear antibody-positive patients as a separate category of juvenile idiopathic arthritis. Ann Rheum Dis. 2015 Feb; 74(2):470-2. PMID: 25384964.
    Citations: 3     Fields:    Translation:Humans
  9. Audia S, Rossato M, Santegoets K, Spijkers S, Wichers C, Bekker C, Bloem A, Boon L, Flinsenberg T, Compeer E, van den Broek T, Facy O, Ortega-Deballon P, Berthier S, Leguy-Seguin V, Martin L, Ciudad M, Samson M, Trad M, Lorcerie B, Janikashvili N, Saas P, Bonnotte B, Radstake TR. Splenic TFH expansion participates in B-cell differentiation and antiplatelet-antibody production during immune thrombocytopenia. Blood. 2014 Oct 30; 124(18):2858-66. PMID: 25232056.
    Citations: 19     Fields:    Translation:HumansCells
  10. Spreafico R, Rossetti M, van den Broek T, Jansen NJ, Zhang H, Moshref M, Prakken B, van Loosdregt J, van Wijk F, Albani S. A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples. Eur J Immunol. 2014 Oct; 44(10):3141-3. PMID: 25042685.
    Citations: 10     Fields:    Translation:HumansCells
  11. Delemarre EM, Roord ST, van den Broek T, Zonneveld-Huijssoon E, de Jager W, Rozemuller H, Martens AC, Broere F, Wulffraat NM, Glant TT, Prakken BJ, van Wijk F. Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and modulation of the Teff cell compartment. Arthritis Rheumatol. 2014 Feb; 66(2):350-6. PMID: 24504807.
    Citations: 3     Fields:    Translation:AnimalsCells
  12. Swart JF, de Roock S, Hofhuis FM, Rozemuller H, van den Broek T, Moerer P, Broere F, van Wijk F, Kuis W, Prakken BJ, Martens AC, Wulffraat NM. Mesenchymal stem cell therapy in proteoglycan induced arthritis. Ann Rheum Dis. 2015 Apr; 74(4):769-77. PMID: 24395558.
    Citations: 14     Fields:    Translation:AnimalsCells
  13. Schadenberg AW, van den Broek T, Siemelink MA, Algra SO, de Jong PR, Jansen NJ, Prakken BJ, van Wijk F. Differential homeostatic dynamics of human regulatory T-cell subsets following neonatal thymectomy. J Allergy Clin Immunol. 2014 Jan; 133(1):277-80.e1-6. PMID: 24139831.
    Citations: 7     Fields:    Translation:HumansCells
  14. de Jong PR, Schadenberg AW, van den Broek T, Beekman JM, van Wijk F, Coffer PJ, Prakken BJ, Jansen NJ. STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass. PLoS One. 2012; 7(4):e35070. PMID: 22506067.
    Citations: 17     Fields:    Translation:HumansCells
  15. Puga Yung GL, Fidler M, Albani E, Spermon N, Teklenburg G, Newbury R, Schechter N, van den Broek T, Prakken B, Billetta R, Dohil R, Albani S. Heat shock protein-derived T-cell epitopes contribute to autoimmune inflammation in pediatric Crohn's disease. PLoS One. 2009 Nov 02; 4(11):e7714. PMID: 19888320.
    Citations: 10     Fields:    Translation:Humans
  16. Koffeman EC, Genovese M, Amox D, Keogh E, Santana E, Matteson EL, Kavanaugh A, Molitor JA, Schiff MH, Posever JO, Bathon JM, Kivitz AJ, Samodal R, Belardi F, Dennehey C, van den Broek T, van Wijk F, Zhang X, Zieseniss P, Le T, Prakken BA, Cutter GC, Albani S. Epitope-specific immunotherapy of rheumatoid arthritis: clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase II trial. Arthritis Rheum. 2009 Nov; 60(11):3207-16. PMID: 19877047.
    Citations: 63     Fields:    Translation:HumansCellsCTClinical Trials
  17. van den Broek T, Bulk S, Pruijs JE, Beek FJ. Radiological "bone within a bone" appearance with atraumatic fractures. Postgrad Med J. 2009 Oct; 85(1008):514. PMID: 19789189.
    Citations: 1     Fields:    Translation:Humans
  18. van den Broek T, Lalezari F, Brouwers HA, Beek FJ. Unilateral thymus displacement. JBR-BTR. 2009 May-Jun; 92(3):174-5. PMID: 19670585.
    Citations:    Fields:    Translation:Humans
  19. Hellings WE, Pasterkamp G, Verhoeven BA, de Kleijn DP, de Vries JP, Seldenrijk CA, van den Broek T, Moll FL. [Differences between men and women in the composition of atherosclerotic plaque, as an explanation for the lower success rate of carotid endarterectomy in women]. Ned Tijdschr Geneeskd. 2008 Nov 29; 152(48):2624-31. PMID: 19102439.
    Citations: 2     Fields:    
  20. van den Broek T, Tesser JR, Albani S. The evolution of biomarkers in rheumatoid arthritis: from clinical research to clinical care. Expert Opin Biol Ther. 2008 Nov; 8(11):1773-85. PMID: 18847311.
    Citations: 2     Fields:    Translation:HumansAnimals
  21. Rodriguez-Feo JA, Hellings WE, Moll FL, De Vries JP, van Middelaar BJ, Algra A, Sluijter J, Velema E, van den Broek T, Sessa WC, De Kleijn DP, Pasterkamp G. Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease. PLoS One. 2008 Jul 02; 3(7):e2612. PMID: 18596970.
    Citations: 13     Fields:    Translation:HumansAnimals
  22. Van Den Broek T, Liqui Lung PF, Suttorp MJ, Eefting FD, Schipper ME, Vink A. Vascular occlusion as a late complication of the Angio-Seal closure device. A review of literature. Minerva Cardioangiol. 2007 Dec; 55(6):815-9. PMID: 18091648.
    Citations: 3     Fields:    Translation:Humans
  23. van den Broek T, Liqui Lung PF, Suttorp MJ, Eefting FD, Schipper ME, Vink A. Arterial occlusion after repetitive angio-seal device closure. Vasc Endovascular Surg. 2007 Aug-Sep; 41(4):346-7. PMID: 17704339.
    Citations:    Fields:    Translation:Humans
  24. Hellings WE, Pasterkamp G, Verhoeven BA, De Kleijn DP, De Vries JP, Seldenrijk KA, van den Broek T, Moll FL. Gender-associated differences in plaque phenotype of patients undergoing carotid endarterectomy. J Vasc Surg. 2007 Feb; 45(2):289-96; discussion 296-7. PMID: 17264005.
    Citations: 29     Fields:    Translation:HumansCells
  25. Hellings WE, Verhoeven BA, Moll FL, Van den Broek T, Pasterkamp G. Pathophysiology of gender difference in prognosis of asymptomatic carotid stenosis: research and future implications. Stroke. 2006 Feb; 37(2):332. PMID: 16397166.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.