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Changyu Shen, Ph.D.

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Biography
University of Science & Technology of China, Anhui, ChinaBS07/1998Biology
University of Pittsburgh, PittsburghPhD05/2004Biostatistics

Overview
Dr. Changyu Shen is a senior biostatistician at the Richard and Susan Smith Center for Outcomes Research in Cardiology at the Beth Israel Deaconess Medical Center. His research areas include empirical Bayesian methods for randomized clinical trials, missing data, causal inference and heterogeneity of treatment effect. His main collaborative area is cardiovascular diseases.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HS024520 (SHEN, CHANGYU) Apr 1, 2016 - Jan 31, 2019
    AHRQ
    A unified method to study heterogeneity in treatment effect
    Role: Principal Investigator
  2. R21CA152463 (LI, LINGLING) Sep 14, 2011 - Aug 31, 2014
    NIH/NCI
    Unified Approaches for Missing Data in Observational Studies
    Role: Co-Principal Investigator
  3. (Changyu Shen) Jul 1, 2008 - Jun 30, 2009
    Showalter Trust
    A Unified Statistical Framework for High-throughput Label-free Protein Quantification Using Mass Spectrometry
    Role Description: The goal of this project is to develop a statistical model for accurate metabolite identification and false discovery rate estimate.
    Role: PI

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li X, Shen C. Doubly Robust Estimation of Causal Effect: Upping the Odds of Getting the Right Answers. Circ Cardiovasc Qual Outcomes. 2020 Jan; 13(1):e006065. PMID: 31888348.
    Citations:    
  2. Wasfy JH, Bhambhani V, Healy EW, Choirat C, Dominici F, Wadhera RK, Shen C, Wang Y, Yeh RW. Relative Effects of the Hospital Readmissions Reduction Program on Hospitals That Serve Poorer Patients. Med Care. 2019 Dec; 57(12):968-976. PMID: 31567860.
    Citations:    
  3. Anderson JD, Wadhera RK, Joynt Maddox KE, Wang Y, Shen C, Stevens JP, Yeh RW. Thirty-Day Spending and Outcomes for an Episode of Pneumonia Care Among Medicare Beneficiaries. Chest. 2019 Nov 21. PMID: 31759965.
    Citations:    
  4. Kusayama T, Douglas A, Wan J, Doytchinova A, Wong J, Mitscher G, Straka S, Shen C, Everett TH, Chen PS. Skin sympathetic nerve activity and ventricular rate control during atrial fibrillation. Heart Rhythm. 2019 Nov 19. PMID: 31756526.
    Citations:    
  5. Wadhera RK, Khatana SAM, Choi E, Jiang G, Shen C, Yeh RW, Joynt Maddox KE. Disparities in Care and Mortality Among Homeless Adults Hospitalized for Cardiovascular Conditions. JAMA Intern Med. 2019 Nov 18. PMID: 31738826.
    Citations:    
  6. Strom JB, Zhao Y, Faridi KF, Tamez H, Butala NM, Valsdottir LR, Curtis J, Brennan JM, Shen C, Boulware M, Popma JJ, Yeh RW. Comparison of Clinical Trials and Administrative Claims to Identify Stroke Among Patients Undergoing Aortic Valve Replacement: Findings From the EXTEND Study. Circ Cardiovasc Interv. 2019 Nov; 12(11):e008231. PMID: 31694411.
    Citations:    
  7. Kundi H, Wadhera RK, Strom JB, Valsdottir LR, Shen C, Kazi DS, Yeh RW. Association of Frailty With 30-Day Outcomes for Acute Myocardial Infarction, Heart Failure, and Pneumonia Among Elderly Adults. JAMA Cardiol. 2019 Sep 25. PMID: 31553402.
    Citations:    
  8. Muensterman ET, Jaynes HA, Sowinski KM, Overholser BR, Shen C, Kovacs RJ, Tisdale JE. Effect of Transdermal Testosterone and Oral Progesterone on Drug-Induced QT Interval Lengthening in Older Men: A Randomized, Double-Blind, Placebo-Controlled Crossover-Design Study. Circulation. 2019 Sep 24; 140(13):1127-1129. PMID: 31545681.
    Citations:    
  9. Stabenau HF, Shen C, Tereshchenko LG, Waks JW. Changes in global electrical heterogeneity associated with dofetilide, quinidine, ranolazine, and verapamil. Heart Rhythm. 2019 Sep 17. PMID: 31539628.
    Citations:    
  10. Yin D, Yang N, Tian Z, Wu AZ, Xu D, Chen M, Kamp NJ, Wang Z, Shen C, Chen Z, Lin SF, Rubart-von der Lohe M, Chen PS, Everett TH. Effects of ondansetron on apamin-sensitive small conductance calcium-activated potassium currents in pacing-induced failing rabbit hearts. Heart Rhythm. 2019 Sep 09. PMID: 31513946.
    Citations:    
  11. Jain R, Gautam S, Wu C, Shen C, Jain A, Giesdal O, Chahal H, Lin H, Bluemke DA, Soliman EZ, Nazarian S, Lima JAC. Prognostic implications of QRS dispersion for major adverse cardiovascular events in asymptomatic women and men: the Multi-Ethnic Study of Atherosclerosis. J Interv Card Electrophysiol. 2019 Oct; 56(1):45-53. PMID: 31482330.
    Citations:    
  12. Reeder HT, Shen C, Buxton AE, Haneuse SJ, Kramer DB. Joint Shock/Death Risk Prediction Model for Patients Considering Implantable Cardioverter-Defibrillators. Circ Cardiovasc Qual Outcomes. 2019 Aug; 12(8):e005675. PMID: 31412732.
    Citations:    
  13. Wadhera RK, Joynt Maddox KE, Kazi DS, Shen C, Yeh RW. Hospital revisits within 30 days after discharge for medical conditions targeted by the Hospital Readmissions Reduction Program in the United States: national retrospective analysis. BMJ. 2019 08 12; 366:l4563. PMID: 31405902.
    Citations:    
  14. Taft L, Shen C. A non-parametric statistical test of null treatment effect in sub-populations. J Biopharm Stat. 2019 Jul 15; 1-17. PMID: 31304862.
    Citations:    
  15. Kundi H, Popma JJ, Reynolds MR, Strom JB, Pinto DS, Valsdottir LR, Shen C, Choi E, Yeh RW. Frailty and related outcomes in patients undergoing transcatheter valve therapies in a nationwide cohort. Eur Heart J. 2019 Jul 14; 40(27):2231-2239. PMID: 30977798.
    Citations:    
  16. Khatana SAM, Bhatla A, Nathan AS, Giri J, Shen C, Kazi DS, Yeh RW, Groeneveld PW. Association of Medicaid Expansion With Cardiovascular Mortality. JAMA Cardiol. 2019 Jul 01; 4(7):671-679. PMID: 31166575.
    Citations:    
  17. Kundi H, Cohen DJ, Strom JB, Valsdottir L, Shen C, Choi E, Popma JJ, Yeh RW. Trends in isolated aortic valve replacement in the United States in the early phase of expansion of TAVR. Int J Cardiol. 2019 10 01; 292:68-72. PMID: 31255451.
    Citations:    
  18. Li Q, Liu H, Zhang S, Zhang D, Liu X, He Y, Mi L, Zhang J, Liu C, Shen C, Guo Z. Superhydrophobic Electrically Conductive Paper for Ultrasensitive Strain Sensor with Excellent Anticorrosion and Self-Cleaning Property. ACS Appl Mater Interfaces. 2019 Jun 19; 11(24):21904-21914. PMID: 31124646.
    Citations:    
  19. Yuan Y, Liu X, Wan J, Wong J, Bedwell AA, Persohn SA, Shen C, Fishbein MC, Chen LS, Chen Z, Everett TH, Territo PR, Chen PS. Subcutaneous nerve stimulation for rate control in ambulatory dogs with persistent atrial fibrillation. Heart Rhythm. 2019 Sep; 16(9):1383-1391. PMID: 31150819.
    Citations:    
  20. Ferro EG, Secemsky EA, Wadhera RK, Choi E, Strom JB, Wasfy JH, Wang Y, Shen C, Yeh RW. Patient Readmission Rates For All Insurance Types After Implementation Of The Hospital Readmissions Reduction Program. Health Aff (Millwood). 2019 Apr; 38(4):585-593. PMID: 30933582.
    Citations:    
  21. Danford CJ, Iriana S, Shen C, Curry MP, Lai M. Evidence of bias during liver transplant evaluation of non-alcoholic steatohepatitis cirrhosis patients. Liver Int. 2019 Jun; 39(6):1165-1173. PMID: 30809932.
    Citations:    
  22. Zhang S, Liu H, Yang S, Shi X, Zhang D, Shan C, Mi L, Liu C, Shen C, Guo Z. Ultrasensitive and Highly Compressible Piezoresistive Sensor Based on Polyurethane Sponge Coated with a Cracked Cellulose Nanofibril/Silver Nanowire Layer. ACS Appl Mater Interfaces. 2019 Mar 20; 11(11):10922-10932. PMID: 30794745.
    Citations:    
  23. Strom JB, Tamez H, Zhao Y, Valsdottir LR, Curtis J, Brennan JM, Shen C, Popma JJ, Mauri L, Yeh RW. Validating the use of registries and claims data to support randomized trials: Rationale and design of the Extending Trial-Based Evaluations of Medical Therapies Using Novel Sources of Data (EXTEND) Study. Am Heart J. 2019 Jun; 212:64-71. PMID: 30953936.
    Citations:    
  24. Chung M, Zhao Y, Strom JB, Shen C, Yeh RW. Extracorporeal Membrane Oxygenation Use in Cardiogenic Shock: Impact of Age on In-Hospital Mortality, Length of Stay, and Costs. Crit Care Med. 2019 03; 47(3):e214-e221. PMID: 30585830.
    Citations:    Fields:    
  25. Wan J, Chen M, Yuan Y, Wang Z, Shen C, Fishbein MC, Chen Z, Wong J, Grant MB, Everett TH, Chen PS. Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs. Heart Rhythm. 2019 Aug; 16(8):1251-1260. PMID: 30818091.
    Citations:    
  26. Kusayama T, Wan J, Doytchinova A, Wong J, Kabir RA, Mitscher G, Straka S, Shen C, Everett TH, Chen PS. Skin sympathetic nerve activity and the temporal clustering of cardiac arrhythmias. JCI Insight. 2019 02 21; 4(4). PMID: 30811928.
    Citations:    
  27. Wadhera RK, Sukul D, Secemsky EA, Shen C, Gurm HS, Boden WE, Yeh RW. Temporal Trends in Unstable Angina Diagnosis Codes for Outpatient Percutaneous Coronary Interventions. JAMA Intern Med. 2019 Feb 01; 179(2):259-261. PMID: 30556822.
    Citations:    Fields:    
  28. Strom JB, Shen C, Yeh RW. SCOT-HEART: Does it live up to the PROMISE? J Cardiovasc Comput Tomogr. 2019 May - Jun; 13(3):48-50. PMID: 30638707.
    Citations:    Fields:    
  29. Barkagan M, Shapira-Daniels A, Leshem E, Shen C, Anter E. Pseudoblock of the Posterior Mitral Line With Epicardial Bridging Connections Is a Frequent Cause of Complex Perimitral Tachycardias. Circ Arrhythm Electrophysiol. 2019 01; 12(1):e006933. PMID: 30606034.
    Citations:    Fields:    
  30. Strom JB, Zhao Y, Shen C, Chung M, Pinto DS, Popma JJ, Cohen DJ, Yeh RW. Hospital Variation in the Utilization of Short-Term Nondurable Mechanical Circulatory Support in Myocardial Infarction Complicated by Cardiogenic Shock. Circ Cardiovasc Interv. 2019 01; 12(1):e007270. PMID: 30608880.
    Citations:    Fields:    
  31. Wadhera RK, Choi E, Shen C, Yeh RW, Joynt Maddox KE. Trends, Causes, and Outcomes of Hospitalizations for Homeless Individuals: A Retrospective Cohort Study. Med Care. 2019 01; 57(1):21-27. PMID: 30461584.
    Citations:    Fields:    
  32. Kundi H, Popma JJ, Khabbaz KR, Chu LM, Strom JB, Valsdottir LR, Shen C, Yeh RW. Association of Hospital Surgical Aortic Valve Replacement Quality With 30-Day and 1-Year Mortality After Transcatheter Aortic Valve Replacement. JAMA Cardiol. 2019 Jan 01; 4(1):16-22. PMID: 30516798.
    Citations:    Fields:    
  33. Wadhera RK, Joynt Maddox KE, Wasfy JH, Haneuse S, Shen C, Yeh RW. Association of the Hospital Readmissions Reduction Program With Mortality Among Medicare Beneficiaries Hospitalized for Heart Failure, Acute Myocardial Infarction, and Pneumonia. JAMA. 2018 12 25; 320(24):2542-2552. PMID: 30575880.
    Citations:    Fields:    Translation:Humans
  34. Yeh RW, Valsdottir LR, Yeh MW, Shen C, Kramer DB, Strom JB, Secemsky EA, Healy JL, Domeier RM, Kazi DS, Nallamothu BK. Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial. BMJ. 2018 Dec 13; 363:k5094. PMID: 30545967.
    Citations:    Fields:    
  35. Cheng X, Shi H, Wang Z, Zheng G, Liu P, Dai K, Liu C, Shen C. Bioinspired Concentric-Cylindrical Multilayered Scaffolds with Controllable Architectures: Facile Preparation and Biological Applications. ACS Appl Mater Interfaces. 2018 Dec 19; 10(50):43512-43522. PMID: 30474950.
    Citations:    
  36. Wan J, Chen M, Wang Z, Everett TH, Rubart-von der Lohe M, Shen C, Qu Z, Weiss JN, Boyden PA, Chen PS. Small-conductance calcium-activated potassium current modulates the ventricular escape rhythm in normal rabbit hearts. Heart Rhythm. 2019 Apr; 16(4):615-623. PMID: 30445170.
    Citations:    Fields:    
  37. Kundi H, Strom JB, Valsdottir LR, Elmariah S, Popma JJ, Shen C, Yeh RW. Trends in Isolated Surgical Aortic Valve Replacement According to Hospital-Based Transcatheter Aortic Valve Replacement Volumes. JACC Cardiovasc Interv. 2018 11 12; 11(21):2148-2156. PMID: 30343022.
    Citations:    Fields:    
  38. Kundi H, Popma JJ, Valsdottir LR, Shen C, Faridi KF, Pinto DS, Yeh RW. The Value of Claims-Based Nontraditional Risk Factors in Predicting Long-term Mortality After MitraClip Procedure. Can J Cardiol. 2018 12; 34(12):1648-1654. PMID: 30527154.
    Citations:    Fields:    
  39. Barkagan M, Rottmann M, Leshem E, Shen C, Buxton AE, Anter E. Effect of Baseline Impedance on Ablation Lesion Dimensions. Circ Arrhythm Electrophysiol. 2018 10; 11(10):e006690. PMID: 30354405.
    Citations:    Fields:    
  40. Kundi H, Valsdottir LR, Popma JJ, Cohen DJ, Strom JB, Pinto DS, Shen C, Yeh RW. Impact of a Claims-Based Frailty Indicator on the Prediction of Long-Term Mortality After Transcatheter Aortic Valve Replacement in Medicare Beneficiaries. Circ Cardiovasc Qual Outcomes. 2018 10; 11(10):e005048. PMID: 30354574.
    Citations:    Fields:    
  41. Kundi H, Popma JJ, Cohen DJ, Liu DC, Laham RJ, Pinto DS, Chu LM, Strom JB, Shen C, Yeh RW. Prevalence and Outcomes of Isolated Tricuspid Valve Surgery Among Medicare Beneficiaries. Am J Cardiol. 2019 01 01; 123(1):132-138. PMID: 30442362.
    Citations:    Fields:    
  42. Ko SQ, Valsdottir LR, Strom JB, Cheng YC, Hirayama A, Liu PH, Yanagisawa N, Yen H, Shen C, Yeh RW. Meta-Analysis of Bleeding Risk Prediction Scores in Patients After Percutaneous Coronary Intervention on Dual Antiplatelet Therapy. Am J Cardiol. 2018 12 01; 122(11):1843-1852. PMID: 30309627.
    Citations:    Fields:    
  43. Anter E, Duytschaever M, Shen C, Strisciuglio T, Leshem E, Contreras-Valdes FM, Waks JW, Zimetbaum PJ, Kumar K, Spector PS, Lee A, Gerstenfeld EP, Nakar E, Bar-Tal M, Buxton AE. Activation Mapping With Integration of Vector and Velocity Information Improves the Ability to Identify the Mechanism and Location of Complex Scar-Related Atrial Tachycardias. Circ Arrhythm Electrophysiol. 2018 08; 11(8):e006536. PMID: 30354312.
    Citations:    Fields:    
  44. Blumenthal DM, Valsdottir LR, Zhao Y, Shen C, Kirtane AJ, Pinto DS, Resnic FS, Maddox KEJ, Wasfy JH, Mehran R, Rosenfield K, Yeh RW. A Survey of Interventional Cardiologists' Attitudes and Beliefs About Public Reporting of Percutaneous Coronary Intervention. JAMA Cardiol. 2018 07 01; 3(7):629-634. PMID: 29801157.
    Citations: 1     Fields:    
  45. Secemsky EA, Shen C, Yeh RW. Exposure Misclassification in Observational Studies: Setting New Standards. Circ Cardiovasc Qual Outcomes. 2018 07; 11(7):e004939. PMID: 29991648.
    Citations:    Fields:    
  46. Jiang Z, Zhao Y, Tsai WC, Yuan Y, Chinda K, Tan J, Onkka P, Shen C, Chen LS, Fishbein MC, Lin SF, Chen PS, Everett TH. Effects of Vagal Nerve Stimulation on Ganglionated Plexi Nerve Activity and Ventricular Rate in Ambulatory Dogs With Persistent Atrial Fibrillation. JACC Clin Electrophysiol. 2018 08; 4(8):1106-1114. PMID: 30139493.
    Citations:    
  47. Wadhera RK, Shen C, Secemsky EA, Strom JB, Yeh RW. State Variation in the Use of Non-Acute Coronary Angiograms and Coronary Revascularization Procedures. JACC Cardiovasc Interv. 2018 05 14; 11(9):912-913. PMID: 29747922.
    Citations:    Fields:    
  48. Shen C. Interval estimation of a population mean using existing knowledge or data on effect sizes. Stat Methods Med Res. 2019 06; 28(6):1703-1715. PMID: 29734870.
    Citations:    Fields:    
  49. Zhao Y, Yuan Y, Tsai WC, Jiang Z, Tian ZP, Shen C, Lin SF, Fishbein MC, Everett TH, Chen Z, Chen PS. Antiarrhythmic effects of stimulating the left dorsal branch of the thoracic nerve in a canine model of paroxysmal atrial tachyarrhythmias. Heart Rhythm. 2018 08; 15(8):1242-1251. PMID: 29654853.
    Citations:    Fields:    
  50. Wadhera RK, Joynt Maddox KE, Wang Y, Shen C, Yeh RW. 30-Day Episode Payments and Heart Failure Outcomes Among Medicare Beneficiaries. JACC Heart Fail. 2018 05; 6(5):379-387. PMID: 29655827.
    Citations:    Fields:    
  51. Strom JB, Zhao Y, Shen C, Chung M, Pinto DS, Popma JJ, Yeh RW. National trends, predictors of use, and in-hospital outcomes in mechanical circulatory support for cardiogenic shock. EuroIntervention. 2018 04 06; 13(18):e2152-e2159. PMID: 29400657.
    Citations:    Fields:    
  52. Shelton RS, Ogawa M, Lin H, Shen C, Wong J, Lin SF, Chen PS, Everett TH. Effects of Stellate Ganglion Cryoablation on Subcutaneous Nerve Activity and Atrial Tachyarrhythmias in a Canine Model of Pacing-Induced Heart Failure. JACC Clin Electrophysiol. 2018 05; 4(5):686-695. PMID: 29798799.
    Citations:    
  53. Butala NM, Kramer DB, Shen C, Strom JB, Kennedy KF, Wang Y, Valsdottir LR, Wasfy JH, Yeh RW. Applicability of Publicly Reported Hospital Readmission Measures to Unreported Conditions and Other Patient Populations: A Cross-sectional All-Payer Study. Ann Intern Med. 2018 05 01; 168(9):631-639. PMID: 29582086.
    Citations:    Fields:    
  54. Ren X, Li S, Shen C, Yu Z. Linear and nonlinear variable selection in competing risks data. Stat Med. 2018 06 15; 37(13):2134-2147. PMID: 29579776.
    Citations:    Fields:    
  55. Faridi KF, Popma JJ, Strom JB, Shen C, Choi E, Yeh RW. Utilization, In-Hospital Mortality, and 30-Day Readmission After Percutaneous Mitral Valve Repair in the United States Shortly After Device Approval. Am J Cardiol. 2018 06 01; 121(11):1365-1372. PMID: 29627105.
    Citations:    Fields:    
  56. Wadhera RK, Joynt Maddox KE, Wang Y, Shen C, Bhatt DL, Yeh RW. Association Between 30-Day Episode Payments and Acute Myocardial Infarction Outcomes Among Medicare Beneficiaries. Circ Cardiovasc Qual Outcomes. 2018 03; 11(3):e004397. PMID: 29530887.
    Citations:    Fields:    
  57. Ko SQ, Strom JB, Shen C, Yeh RW. Mortality, Length of Stay, and Cost of Weekend Admissions. J Hosp Med. 2018 07 01; 13(7):476-481. PMID: 29370319.
    Citations:    Fields:    
  58. Yin D, Chen M, Yang N, Wu AZ, Xu D, Tsai WC, Yuan Y, Tian Z, Chan YH, Shen C, Chen Z, Lin SF, Weiss JN, Chen PS, Everett TH. Role of apamin-sensitive small conductance calcium-activated potassium currents in long-term cardiac memory in rabbits. Heart Rhythm. 2018 05; 15(5):761-769. PMID: 29325977.
    Citations:    Fields:    Translation:Animals
  59. Layton J, Li X, Shen C, de Groot M, Lange L, Correa A, Wessel J. Type 2 Diabetes Genetic Risk Scores Are Associated With Increased Type 2 Diabetes Risk Among African Americans by Cardiometabolic Status. Clin Med Insights Endocrinol Diabetes. 2018; 11:1179551417748942. PMID: 29326538.
    Citations:    
  60. Kabir RA, Doytchinova A, Liu X, Adams D, Straka S, Chen LS, Shen C, Lin SF, Everett TH, Chen PS. Crescendo Skin Sympathetic Nerve Activity and Ventricular Arrhythmia. J Am Coll Cardiol. 2017 12 26; 70(25):3201-3202. PMID: 29268931.
    Citations:    Fields:    
  61. Secemsky EA, Schermerhorn M, Carroll BJ, Kennedy KF, Shen C, Valsdottir LR, Landon B, Yeh RW. Readmissions After Revascularization Procedures for Peripheral Arterial Disease: A Nationwide Cohort Study. Ann Intern Med. 2018 01 16; 168(2):93-99. PMID: 29204656.
    Citations:    Fields:    Translation:Humans
  62. Yuan Y, Jiang Z, Zhao Y, Tsai WC, Patel J, Chen LS, Shen C, Lin SF, Chen HV, Everett TH, Fishbein MC, Chen Z, Chen PS. Long-term intermittent high-amplitude subcutaneous nerve stimulation reduces sympathetic tone in ambulatory dogs. Heart Rhythm. 2018 03; 15(3):451-459. PMID: 29081397.
    Citations:    Fields:    Translation:Animals
  63. Shen C, Li X. Using previous trial results to inform hypothesis testing of new interventions. J Biopharm Stat. 2018; 28(5):884-892. PMID: 29157104.
    Citations:    Fields:    
  64. Temu TM, Lane KA, Shen C, Ng'ang'a L, Akwanalo CO, Chen PS, Emonyi W, Heckbert SR, Koech MM, Manji I, Vatta M, Velazquez EJ, Wessel J, Kimaiyo S, Inui TS, Bloomfield GS. Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya. PLoS One. 2017; 12(9):e0185204. PMID: 28934312.
    Citations:    Fields:    Translation:Humans
  65. Yuan Y, Hassel JL, Doytchinova A, Adams D, Wright KC, Meshberger C, Chen LS, Guerra MP, Shen C, Lin SF, Everett TH, Salanova V, Chen PS. Left cervical vagal nerve stimulation reduces skin sympathetic nerve activity in patients with drug resistant epilepsy. Heart Rhythm. 2017 12; 14(12):1771-1778. PMID: 28778733.
    Citations: 1     Fields:    Translation:Humans
  66. Strom JB, Kramer DB, Wang Y, Shen C, Wasfy JH, Landon BE, Wilker EH, Yeh RW. Short-term rehospitalization across the spectrum of age and insurance types in the United States. PLoS One. 2017; 12(7):e0180767. PMID: 28700736.
    Citations: 3     Fields:    Translation:Humans
  67. Shen MJ, Coffey AC, Straka S, Adams DE, Wagner DB, Kovacs RJ, Clark M, Shen C, Chen LS, Everett TH, Lin SF, Chen PS. Simultaneous recordings of intrinsic cardiac nerve activity and skin sympathetic nerve activity from human patients during the postoperative period. Heart Rhythm. 2017 11; 14(11):1587-1593. PMID: 28648667.
    Citations: 1     Fields:    Translation:Humans
  68. Reher TA, Wang Z, Hsueh CH, Chang PC, Pan Z, Kumar M, Patel J, Tan J, Shen C, Chen Z, Fishbein MC, Rubart M, Boyden P, Chen PS. Small-Conductance Calcium-Activated Potassium Current in Normal Rabbit Cardiac Purkinje Cells. J Am Heart Assoc. 2017 May 26; 6(6). PMID: 28550095.
    Citations: 1     Fields:    Translation:AnimalsCells
  69. Hunter BR, Collins SP, Fermann GJ, Levy PD, Shen C, Ayaz SI, Cole ML, Miller KF, Soliman AA, Pang PS. Design and rationale of the high-sensitivity Troponin T Rules Out Acute Cardiac Insufficiency Trial. Pragmat Obs Res. 2017; 8:85-90. PMID: 28572743.
    Citations:    
  70. Pang PS, Lane KA, Tavares M, Storrow AB, Shen C, Peacock WF, Nowak R, Mebazaa A, Laribi S, Hollander JE, Gheorghiade M, Collins SP. Is there a clinically meaningful difference in patient reported dyspnea in acute heart failure? An analysis from URGENT Dyspnea. Heart Lung. 2017 Jul - Aug; 46(4):300-307. PMID: 28433323.
    Citations:    Fields:    Translation:Humans
  71. Strom JB, Whelan JB, Shen C, Zheng SQ, Mortele KJ, Kramer DB. Safety and utility of magnetic resonance imaging in patients with cardiac implantable electronic devices. Heart Rhythm. 2017 08; 14(8):1138-1144. PMID: 28385671.
    Citations: 2     Fields:    Translation:Humans
  72. Uradu A, Wan J, Doytchinova A, Wright KC, Lin AYT, Chen LS, Shen C, Lin SF, Everett TH, Chen PS. Skin sympathetic nerve activity precedes the onset and termination of paroxysmal atrial tachycardia and fibrillation. Heart Rhythm. 2017 07; 14(7):964-971. PMID: 28347833.
    Citations: 4     Fields:    Translation:Humans
  73. Yin D, Hsieh YC, Tsai WC, Wu AZ, Jiang Z, Chan YH, Xu D, Yang N, Shen C, Chen Z, Lin SF, Chen PS, Everett TH. Role of Apamin-Sensitive Calcium-Activated Small-Conductance Potassium Currents on the Mechanisms of Ventricular Fibrillation in Pacing-Induced Failing Rabbit Hearts. Circ Arrhythm Electrophysiol. 2017 02; 10(2):e004434. PMID: 28213506.
    Citations:    Fields:    Translation:AnimalsCells
  74. Ajam T, Kalra V, Shen C, Li X, Gautam S, Kambur T, Barmeda M, Yancey KW, Ajam S, Garlie J, Miller JM, Jain R. Natural History of Implantable Cardioverter-Defibrillator Implanted at or after the Age of 70 years in a Veteran Population: A Single Center Study. J Atr Fibrillation. 2016 Dec; 9(4):1496. PMID: 29250256.
    Citations:    
  75. Hellman Y, Malik AS, Lane KA, Shen C, Wang IW, Wozniak TC, Hashmi ZA, Munson SD, Pickrell J, Caccamo MA, Gradus-Pizlo I, Hadi A. Pulse Oximeter Derived Blood Pressure Measurement in Patients With a Continuous Flow Left Ventricular Assist Device. Artif Organs. 2017 May; 41(5):424-430. PMID: 27782305.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  76. Tsai WC, Chan YH, Chinda K, Chen Z, Patel J, Shen C, Zhao Y, Jiang Z, Yuan Y, Ye M, Chen LS, Riley AA, Persohn SA, Territo PR, Everett TH, Lin SF, Vinters HV, Fishbein MC, Chen PS. Effects of renal sympathetic denervation on the stellate ganglion and brain stem in dogs. Heart Rhythm. 2017 02; 14(2):255-262. PMID: 27720832.
    Citations: 6     Fields:    Translation:Animals
  77. Doytchinova A, Hassel JL, Yuan Y, Lin H, Yin D, Adams D, Straka S, Wright K, Smith K, Wagner D, Shen C, Salanova V, Meshberger C, Chen LS, Kincaid JC, Coffey AC, Wu G, Li Y, Kovacs RJ, Everett TH, Victor R, Cha YM, Lin SF, Chen PS. Simultaneous noninvasive recording of skin sympathetic nerve activity and electrocardiogram. Heart Rhythm. 2017 01; 14(1):25-33. PMID: 27670627.
    Citations: 9     Fields:    Translation:Humans
  78. Shen C, Liu Z, Xu H, Liu H, Yue C. Control of false positives in randomized phase III clinical trials. J Biopharm Stat. 2017; 27(5):719-731. PMID: 27653151.
    Citations:    Fields:    
  79. Buxton AE, Waks JW, Shen C, Chen PS. Risk stratification for sudden cardiac death in North America - current perspectives. J Electrocardiol. 2016 Nov - Dec; 49(6):817-823. PMID: 27524476.
    Citations: 1     Fields:    Translation:Humans
  80. Li X, Xu H, Shen C, Grannis S. Automated linkage of patient records from disparate sources. Stat Methods Med Res. 2018 01; 27(1):172-184. PMID: 28034172.
    Citations:    Fields:    
  81. Shen C, Hu Y, Li X, Wang Y, Chen PS, Buxton AE. Identification of subpopulations with distinct treatment benefit rate using the Bayesian tree. Biom J. 2016 Nov; 58(6):1357-1375. PMID: 27356196.
    Citations:    Fields:    Translation:Humans
  82. Chou HY, Steenburg SD, Dunkle JW, Gussick SD, Petersen MJ, Kohli MD, Shen C, Lin H. Streamlining emergent hand and wrist radiography with a modified four-view protocol. Emerg Radiol. 2016 Aug; 23(4):333-8. PMID: 27220651.
    Citations:    Fields:    Translation:Humans
  83. Tsai WC, Chan YH, Hsueh CH, Everett TH, Chang PC, Choi EK, Olaopa MA, Lin SF, Shen C, Kudela MA, Rubart-von der Lohe M, Chen Z, Jadiya P, Tomar D, Luvison E, Anzalone N, Patel VV, Chen PS. Small conductance calcium-activated potassium current and the mechanism of atrial arrhythmia in mice with dysfunctional melanocyte-like cells. Heart Rhythm. 2016 07; 13(7):1527-35. PMID: 26961301.
    Citations: 5     Fields:    Translation:AnimalsCells
  84. Zhao Y, Chen NX, Shirazi JT, Shen C, Lin SF, Fishbein MC, Moe SM, Chen PS. Subcutaneous nerve activity and mechanisms of sudden death in a rat model of chronic kidney disease. Heart Rhythm. 2016 05; 13(5):1105-1112. PMID: 26744093.
    Citations: 2     Fields:    Translation:Animals
  85. Shen C, Li X. On the uncertainty of individual prediction because of sampling predictors. Stat Med. 2016 05 30; 35(12):2016-30. PMID: 26712471.
    Citations:    Fields:    Translation:Humans
  86. Chinda K, Tsai WC, Chan YH, Lin AY, Patel J, Zhao Y, Tan AY, Shen MJ, Lin H, Shen C, Chattipakorn N, Rubart-von der Lohe M, Chen LS, Fishbein MC, Lin SF, Chen Z, Chen PS. Intermittent left cervical vagal nerve stimulation damages the stellate ganglia and reduces the ventricular rate during sustained atrial fibrillation in ambulatory dogs. Heart Rhythm. 2016 Mar; 13(3):771-80. PMID: 26607063.
    Citations: 8     Fields:    Translation:Animals
  87. Tierney WM, Sidle JE, Diero LO, Sudoi A, Kiplagat J, Macharia S, Shen C, Yeung A, Were MC, Slaven JE, Wools-Kaloustian K. Assessing the impact of a primary care electronic medical record system in three Kenyan rural health centers. J Am Med Inform Assoc. 2016 05; 23(3):544-52. PMID: 26260246.
    Citations: 2     Fields:    Translation:Humans
  88. Were MC, Kessler J, Shen C, Sidle J, Macharia S, Lizcano J, Siika A, Wools-Kaloustian K, Kurth A. Implementation and Operational Research: A Time-Motion Analysis of HIV Transmission Prevention Counseling and Antiretroviral Adherence Messages in Western Kenya. J Acquir Immune Defic Syndr. 2015 Aug 01; 69(4):e135-41. PMID: 25950208.
    Citations:    Fields:    Translation:Humans
  89. Whitesell RT, Steenburg SD, Shen C, Lin H. Facial Fracture in the Setting of Whole-Body CT for Trauma: Incidence and Clinical Predictors. AJR Am J Roentgenol. 2015 Jul; 205(1):W4-10. PMID: 26102417.
    Citations: 3     Fields:    Translation:Humans
  90. Bloomfield GS, Temu TM, Akwanalo CO, Chen PS, Emonyi W, Heckbert SR, Koech MM, Manji I, Shen C, Vatta M, Velazquez EJ, Wessel J, Kimaiyo S, Inui TS. Genetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL). Am Heart J. 2015 Sep; 170(3):455-64.e5. PMID: 26385028.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  91. Shen C, Yu Z, Liu Z. The use of statistics in heart rhythm research: a review. Heart Rhythm. 2015 Jun; 12(6):1376-86. PMID: 26002137.
    Citations:    Fields:    
  92. Steenburg SD, Petersen MJ, Shen C, Lin H. Multi-detector CT of blunt mesenteric injuries: usefulness of imaging findings for predicting surgically significant bowel injuries. Abdom Imaging. 2015 Jun; 40(5):1026-33. PMID: 25296995.
    Citations: 1     Fields:    Translation:Humans
  93. Shen C, Li X, Jeong J. Estimation of treatment effect in a subpopulation: An empirical Bayes approach. J Biopharm Stat. 2016; 26(3):507-18. PMID: 26010422.
    Citations:    Fields:    Translation:Humans
  94. Yu CC, Corr C, Shen C, Shelton R, Yadava M, Rhea IB, Straka S, Fishbein MC, Chen Z, Lin SF, Lopshire JC, Chen PS. Small conductance calcium-activated potassium current is important in transmural repolarization of failing human ventricles. Circ Arrhythm Electrophysiol. 2015 Jun; 8(3):667-76. PMID: 25908692.
    Citations: 9     Fields:    Translation:Humans
  95. Hellman Y, Malik AS, Lin H, Shen C, Wang IW, Wozniak TC, Hashmi ZA, Pickrell J, Jani M, Caccamo MA, Gradus-Pizlo I, Hadi A. B-Type Natriuretic Peptide Levels Predict Ventricular Arrhythmia Post Left Ventricular Assist Device Implantation. Artif Organs. 2015 Dec; 39(12):1051-5. PMID: 25864448.
    Citations:    Fields:    Translation:Humans
  96. Chan YH, Tsai WC, Shen C, Han S, Chen LS, Lin SF, Chen PS. Subcutaneous nerve activity is more accurate than heart rate variability in estimating cardiac sympathetic tone in ambulatory dogs with myocardial infarction. Heart Rhythm. 2015 Jul; 12(7):1619-27. PMID: 25778433.
    Citations: 2     Fields:    Translation:Animals
  97. Hellman Y, Malik AS, Lin H, Shen C, Wang IW, Wozniak TC, Hashmi ZA, Shaukat A, Pickrell J, Caccamo MA, Gradus-Pizlo I, Hadi A. B-type natriuretic peptide-guided therapy and length of hospital stay post left ventricular assist device implantation. ASAIO J. 2015 Mar-Apr; 61(2):156-60. PMID: 25485560.
    Citations: 3     Fields:    Translation:Humans
  98. Jiang Z, Zhao Y, Doytchinova A, Kamp NJ, Tsai WC, Yuan Y, Adams D, Wagner D, Shen C, Chen LS, Everett TH, Lin SF, Chen PS. Using skin sympathetic nerve activity to estimate stellate ganglion nerve activity in dogs. Heart Rhythm. 2015 Jun; 12(6):1324-32. PMID: 25681792.
    Citations: 8     Fields:    Translation:Animals
  99. Li X, Girman CJ, Ofner S, Shen C, Brodovicz KG, Simonaitis L, Santanello N. Sensitivity analysis of methods for active surveillance of acute myocardial infarction using electronic databases. Epidemiology. 2015 Jan; 26(1):130-2. PMID: 25390030.
    Citations:    Fields:    Translation:Humans
  100. Shen C, Wang Y, Chu J, Lu Y, Li Y, Dong X. Optical fiber axial micro-displacement sensor based on Mach-Zehnder interferometer. Opt Express. 2014 Dec 29; 22(26):31984-92. PMID: 25607166.
    Citations: 1     Fields:    
  101. Mourad R, Hsu PY, Juan L, Shen C, Koneru P, Lin H, Liu Y, Nephew K, Huang TH, Li L. Estrogen induces global reorganization of chromatin structure in human breast cancer cells. PLoS One. 2014; 9(12):e113354. PMID: 25470140.
    Citations: 11     Fields:    Translation:HumansCells
  102. Doytchinova A, Patel J, Zhou S, Chen LS, Lin H, Shen C, Everett TH, Lin SF, Chen PS. Subcutaneous nerve activity and spontaneous ventricular arrhythmias in ambulatory dogs. Heart Rhythm. 2015 Mar; 12(3):612-620. PMID: 25460171.
    Citations: 6     Fields:    Translation:Animals
  103. Balint BJ, Steenburg SD, Lin H, Shen C, Steele JL, Gunderman RB. Do telephone call interruptions have an impact on radiology resident diagnostic accuracy? Acad Radiol. 2014 Dec; 21(12):1623-8. PMID: 25281360.
    Citations: 11     Fields:    Translation:Humans
  104. Shaukat A, Habib A, Lane KA, Shen C, Khan S, Hellman YM, Boustani M, Malik AS. Anticholinergic medications: an additional contributor to cognitive impairment in the heart failure population? Drugs Aging. 2014 Oct; 31(10):749-54. PMID: 25142050.
    Citations: 1     Fields:    Translation:Humans
  105. Robinson EA, Rhee KS, Doytchinova A, Kumar M, Shelton R, Jiang Z, Kamp NJ, Adams D, Wagner D, Shen C, Chen LS, Everett TH, Fishbein MC, Lin SF, Chen PS. Estimating sympathetic tone by recording subcutaneous nerve activity in ambulatory dogs. J Cardiovasc Electrophysiol. 2015 Jan; 26(1):70-8. PMID: 25091691.
    Citations: 8     Fields:    Translation:Animals
  106. Gökmen-Polar Y, Goswami CP, Toroni RA, Sanders KL, Mehta R, Sirimalle U, Tanasa B, Shen C, Li L, Ivan M, Badve S, Sledge GW. Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer. J Cancer. 2014; 5(8):633-45. PMID: 25157274.
    Citations: 5     
  107. Marino N, Collins JW, Shen C, Caplen NJ, Merchant AS, Gökmen-Polar Y, Goswami CP, Hoshino T, Qian Y, Sledge GW, Steeg PS. Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines. Clin Exp Metastasis. 2014 Oct; 31(7):771-86. PMID: 25086928.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  108. Xie J, Xu B, Li Y, Kang J, Shen C, Wang J, Jin Y, Liu H, Ni K, Dong X, Zhao C, Jin S. High-sensitivity temperature sensor based on a droplet-like fiber circle. Appl Opt. 2014 Jun 20; 53(18):4085-8. PMID: 24979444.
    Citations:    Fields:    
  109. Fang F, Zuo Q, Pilrose J, Wang Y, Shen C, Li M, Wulfridge P, Matei D, Nephew KP. Decitabine reactivated pathways in platinum resistant ovarian cancer. Oncotarget. 2014 Jun 15; 5(11):3579-89. PMID: 25003579.
    Citations: 11     Fields:    Translation:HumansCells
  110. Steenburg SD, Persohn S, Shen C, Dunkle JW, Gussick SD, Petersen MJ, Wisnewski-Rhodes A, Whitesell RT. Iterative reconstruction improves image quality and preserves diagnostic accuracy in the setting of blunt solid organ injuries. Emerg Radiol. 2015 Feb; 22(1):43-51. PMID: 24906680.
    Citations: 1     Fields:    Translation:Humans
  111. Maddur H, Bourdillon PD, Liangpunsakul S, Joseph Tector A, Fridell JA, Ghabril M, Lacerda MA, Bourdillon C, Shen C, Kwo PY. Role of cardiac catheterization and percutaneous coronary intervention in the preoperative assessment and management of patients before orthotopic liver transplantation. Liver Transpl. 2014 Jun; 20(6):664-72. PMID: 24648247.
    Citations: 4     Fields:    Translation:Humans
  112. Kim S, Ouyang M, Jeong J, Shen C, Zhang X. A NEW METHOD OF PEAK DETECTION FOR ANALYSIS OF COMPREHENSIVE TWO-DIMENSIONAL GAS CHROMATOGRAPHY MASS SPECTROMETRY DATA. Ann Appl Stat. 2014 Jun; 8(2):1209-1231. PMID: 25264474.
    Citations: 1     
  113. Hoang A, Shen C, Zheng J, Taylor S, Groh WJ, Rosenman M, Buxton AE, Chen PS. Utilization rates of implantable cardioverter-defibrillators for primary prevention of sudden cardiac death: a 2012 calculation for a midwestern health referral region. Heart Rhythm. 2014 May; 11(5):849-55. PMID: 24566233.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  114. Njoku VC, Howard TJ, Shen C, Zyromski NJ, Schmidt CM, Pitt HA, Nakeeb A, Lillemoe KD. Pyogenic liver abscess following pancreaticoduodenectomy: risk factors, treatment, and long-term outcome. J Gastrointest Surg. 2014 May; 18(5):922-8. PMID: 24510300.
    Citations: 5     Fields:    Translation:Humans
  115. Hellyer J, George Akingba A, Rhee KS, Tan AY, Lane KA, Shen C, Patel J, Fishbein MC, Chen PS. Autonomic nerve activity and blood pressure in ambulatory dogs. Heart Rhythm. 2014 Feb; 11(2):307-13. PMID: 24275433.
    Citations:    Fields:    Translation:Animals
  116. Akingba AG, Bojalian M, Shen C, Rubin J. Managing recurrent carotid artery disease with redo carotid endarterectomy: a 10-year retrospective case series. Ann Vasc Surg. 2014 May; 28(4):908-16. PMID: 24529820.
    Citations: 1     Fields:    Translation:Humans
  117. Timmons T, Shen C, Aldrovandi G, Rollie A, Gupta SK, Stein JH, Dubé MP. Microbial translocation and metabolic and body composition measures in treated and untreated HIV infection. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):272-7. PMID: 24033288.
    Citations: 7     Fields:    Translation:Humans
  118. Shen C, Li X, Li L. Inverse probability weighting for covariate adjustment in randomized studies. Stat Med. 2014 Feb 20; 33(4):555-68. PMID: 24038458.
    Citations: 4     Fields:    Translation:Humans
  119. Shen C, Jeong J, Li X, Chen PS, Buxton A. Treatment benefit and treatment harm rate to characterize heterogeneity in treatment effect. Biometrics. 2013 Sep; 69(3):724-31. PMID: 23865447.
    Citations:    Fields:    Translation:Humans
  120. Mun HS, Shen C, Pak HN, Lee MH, Lin SF, Chen PS, Joung B. Chronic amiodarone therapy impairs the function of the superior sinoatrial node in patients with atrial fibrillation. Circ J. 2013; 77(9):2255-63. PMID: 23739532.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  121. Lee YS, Chang PC, Hsueh CH, Maruyama M, Park HW, Rhee KS, Hsieh YC, Shen C, Weiss JN, Chen Z, Lin SF, Chen PS. Apamin-sensitive calcium-activated potassium currents in rabbit ventricles with chronic myocardial infarction. J Cardiovasc Electrophysiol. 2013 Oct; 24(10):1144-53. PMID: 23718850.
    Citations: 14     Fields:    Translation:Animals
  122. Jeong J, Zhang X, Shi X, Kim S, Shen C. An efficient post-hoc integration method improving peak alignment of metabolomics data from GCxGC/TOF-MS. BMC Bioinformatics. 2013 Apr 10; 14:123. PMID: 23575005.
    Citations: 3     Fields:    Translation:Animals
  123. Were MC, Nyandiko WM, Huang KT, Slaven JE, Shen C, Tierney WM, Vreeman RC. Computer-generated reminders and quality of pediatric HIV care in a resource-limited setting. Pediatrics. 2013 Mar; 131(3):e789-96. PMID: 23439898.
    Citations: 7     Fields:    Translation:Humans
  124. Hsieh YC, Chang PC, Hsueh CH, Lee YS, Shen C, Weiss JN, Chen Z, Ai T, Lin SF, Chen PS. Apamin-sensitive potassium current modulates action potential duration restitution and arrhythmogenesis of failing rabbit ventricles. Circ Arrhythm Electrophysiol. 2013 Apr; 6(2):410-8. PMID: 23420832.
    Citations: 22     Fields:    Translation:Animals
  125. Shen MJ, Park HW, George Akingba A, Chang PC, Lin SF, Shen C, Chen LS, Chen Z, Fishbein MC, Chiamvimonvat N, Chen PS. Low-level vagus nerve stimulation upregulates small conductance calcium-activated potassium channels in the stellate ganglion. Heart Rhythm. 2013 Jun; 10(6):910-5. PMID: 23357541.
    Citations: 16     Fields:    Translation:AnimalsCells
  126. Gupta SK, Shen C, Moe SM, Kamendulis LM, Goldman M, Dubé MP. Worsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective study. PLoS One. 2012; 7(9):e45716. PMID: 23029197.
    Citations: 14     Fields:    Translation:Humans
  127. Blodget E, Shen C, Aldrovandi G, Rollie A, Gupta SK, Stein JH, Dubé MP. Relationship between microbial translocation and endothelial function in HIV infected patients. PLoS One. 2012; 7(8):e42624. PMID: 22952600.
    Citations: 17     Fields:    Translation:Humans
  128. Teng M, Wang Y, Kim S, Li L, Shen C, Wang G, Liu Y, Huang TH, Nephew KP, Balch C. Empirical bayes model comparisons for differential methylation analysis. Comp Funct Genomics. 2012; 2012:376706. PMID: 22956892.
    Citations: 1     
  129. Bell AJ, Wools-Kaloustian K, Kimaiyo S, Liu H, Katschke A, Shen C, Simiyu G, Musick BS, Sidle JE, Siika A, Braitstein P. Short-Term Rationing of Combination Antiretroviral Therapy: Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya. AIDS Res Treat. 2012; 2012:814564. PMID: 22690332.
    Citations: 1     
  130. Park HW, Shen MJ, Han S, Shinohara T, Maruyama M, Lee YS, Shen C, Hwang C, Chen LS, Fishbein MC, Lin SF, Chen PS. Neural control of ventricular rate in ambulatory dogs with pacing-induced sustained atrial fibrillation. Circ Arrhythm Electrophysiol. 2012 Jun 01; 5(3):571-80. PMID: 22586260.
    Citations: 5     Fields:    Translation:Animals
  131. Matei D, Fang F, Shen C, Schilder J, Arnold A, Zeng Y, Berry WA, Huang T, Nephew KP. Epigenetic resensitization to platinum in ovarian cancer. Cancer Res. 2012 May 01; 72(9):2197-205. PMID: 22549947.
    Citations: 97     Fields:    Translation:HumansCellsCTClinical Trials
  132. Han S, Kobayashi K, Joung B, Piccirillo G, Maruyama M, Vinters HV, March K, Lin SF, Shen C, Fishbein MC, Chen PS, Chen LS. Electroanatomic remodeling of the left stellate ganglion after myocardial infarction. J Am Coll Cardiol. 2012 Mar 06; 59(10):954-61. PMID: 22381432.
    Citations: 32     Fields:    Translation:AnimalsCells
  133. Lee YS, Maruyama M, Chang PC, Park HW, Rhee KS, Hsieh YC, Hsueh CH, Shen C, Lin SF, Hwang HS, Yin H, Knollmann BC, Chen PS. Ryanodine receptor inhibition potentiates the activity of Na channel blockers against spontaneous calcium elevations and delayed afterdepolarizations in Langendorff-perfused rabbit ventricles. Heart Rhythm. 2012 Jul; 9(7):1125-32. PMID: 22387372.
    Citations: 8     Fields:    Translation:Animals
  134. Jeong J, Shi X, Zhang X, Kim S, Shen C. Model-based peak alignment of metabolomic profiling from comprehensive two-dimensional gas chromatography mass spectrometry. BMC Bioinformatics. 2012 Feb 08; 13:27. PMID: 22316124.
    Citations: 6     Fields:    Translation:Animals
  135. Kosgei RJ, Lubano KM, Shen C, Wools-Kaloustian KK, Musick BS, Siika AM, Mabeya H, Carter EJ, Mwangi A, Kiarie J. Impact of integrated family planning and HIV care services on contraceptive use and pregnancy outcomes: a retrospective cohort study. J Acquir Immune Defic Syndr. 2011 Dec 15; 58(5):e121-6. PMID: 21963940.
    Citations: 12     Fields:    Translation:Humans
  136. Shinohara T, Shen MJ, Han S, Maruyama M, Park HW, Fishbein MC, Shen C, Chen PS, Lin SF. Heart failure decreases nerve activity in the right atrial ganglionated plexus. J Cardiovasc Electrophysiol. 2012 Apr; 23(4):404-12. PMID: 22035201.
    Citations: 6     Fields:    Translation:Animals
  137. Bhakta D, Shen C, Kron J, Epstein AE, Pascuzzi RM, Groh WJ. Pacemaker and implantable cardioverter-defibrillator use in a US myotonic dystrophy type 1 population. J Cardiovasc Electrophysiol. 2011 Dec; 22(12):1369-75. PMID: 22035077.
    Citations: 6     Fields:    Translation:Humans
  138. Gupta SK, Shen C, Mather KJ, Agarwal R, Dubé MP. Neither proteinuria nor albuminuria is associated with endothelial dysfunction in HIV-infected patients without diabetes or hypertension. J Infect Dis. 2011 Dec 15; 204(12):1946-50. PMID: 22013226.
    Citations: 5     Fields:    Translation:Humans
  139. Joung B, Hwang HJ, Pak HN, Lee MH, Shen C, Lin SF, Chen PS. Abnormal response of superior sinoatrial node to sympathetic stimulation is a characteristic finding in patients with atrial fibrillation and symptomatic bradycardia. Circ Arrhythm Electrophysiol. 2011 Dec; 4(6):799-807. PMID: 22007035.
    Citations: 4     Fields:    Translation:Humans
  140. Jeong J, Shi X, Zhang X, Kim S, Shen C. An empirical Bayes model using a competition score for metabolite identification in gas chromatography mass spectrometry. BMC Bioinformatics. 2011 Oct 10; 12:392. PMID: 21985394.
    Citations: 5     Fields:    Translation:Animals
  141. Wang Y, Zhao CL, Hu L, Dong X, Jin Y, Shen C, Jin S. A tilt sensor with a compact dimension based on a long-period fiber grating. Rev Sci Instrum. 2011 Sep; 82(9):093106. PMID: 21974572.
    Citations:    Fields:    
  142. Shen C, Li X, Li L, Were MC. Sensitivity analysis for causal inference using inverse probability weighting. Biom J. 2011 Sep; 53(5):822-37. PMID: 21770046.
    Citations: 4     Fields:    Translation:Humans
  143. Li L, Shen C, Li X, Robins JM. On weighting approaches for missing data. Stat Methods Med Res. 2013 Feb; 22(1):14-30. PMID: 21705435.
    Citations: 17     Fields:    
  144. Fishel ML, Jiang Y, Rajeshkumar NV, Scandura G, Sinn AL, He Y, Shen C, Jones DR, Pollok KE, Ivan M, Maitra A, Kelley MR. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth. Mol Cancer Ther. 2011 Sep; 10(9):1698-708. PMID: 21700832.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  145. Gupta SK, Ong'or WO, Shen C, Musick B, Goldman M, Wools-Kaloustian K. Reduced renal function is associated with progression to AIDS but not with overall mortality in HIV-infected Kenyan adults not initially requiring combination antiretroviral therapy. J Int AIDS Soc. 2011 Jun 11; 14:31. PMID: 21663693.
    Citations: 6     Fields:    Translation:Humans
  146. Li X, Shen C. Linkage of patient records from disparate sources. Stat Methods Med Res. 2013 Feb; 22(1):31-8. PMID: 21665896.
    Citations: 6     Fields:    
  147. Li L, Shen C, Wu AC, Li X. Propensity score-based sensitivity analysis method for uncontrolled confounding. Am J Epidemiol. 2011 Aug 01; 174(3):345-53. PMID: 21659349.
    Citations: 8     Fields:    Translation:Humans
  148. Shen MJ, Shinohara T, Park HW, Frick K, Ice DS, Choi EK, Han S, Maruyama M, Sharma R, Shen C, Fishbein MC, Chen LS, Lopshire JC, Zipes DP, Lin SF, Chen PS. Continuous low-level vagus nerve stimulation reduces stellate ganglion nerve activity and paroxysmal atrial tachyarrhythmias in ambulatory canines. Circulation. 2011 May 24; 123(20):2204-12. PMID: 21555706.
    Citations: 42     Fields:    Translation:Animals
  149. Shen C, Huang Y, Liu Y, Wang G, Zhao Y, Wang Z, Teng M, Wang Y, Flockhart DA, Skaar TC, Yan P, Nephew KP, Huang TH, Li L. A modulated empirical Bayes model for identifying topological and temporal estrogen receptor a regulatory networks in breast cancer. BMC Syst Biol. 2011 May 09; 5:67. PMID: 21554733.
    Citations: 16     Fields:    Translation:HumansCells
  150. Groh WJ, Groh MR, Shen C, Monckton DG, Bodkin CL, Pascuzzi RM. Survival and CTG repeat expansion in adults with myotonic dystrophy type 1. Muscle Nerve. 2011 May; 43(5):648-51. PMID: 21484823.
    Citations: 15     Fields:    Translation:HumansCells
  151. Chua SK, Chang PC, Maruyama M, Turker I, Shinohara T, Shen MJ, Chen Z, Shen C, Rubart-von der Lohe M, Lopshire JC, Ogawa M, Weiss JN, Lin SF, Ai T, Chen PS. Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles. Circ Res. 2011 Apr 15; 108(8):971-9. PMID: 21350217.
    Citations: 59     Fields:    Translation:AnimalsCellsPHPublic Health
  152. Were MC, Shen C, Tierney WM, Mamlin JJ, Biondich PG, Li X, Kimaiyo S, Mamlin BW. Evaluation of computer-generated reminders to improve CD4 laboratory monitoring in sub-Saharan Africa: a prospective comparative study. J Am Med Inform Assoc. 2011 Mar-Apr; 18(2):150-5. PMID: 21252053.
    Citations: 12     Fields:    Translation:Humans
  153. Bhakta D, Groh MR, Shen C, Pascuzzi RM, Groh WJ. Increased mortality with left ventricular systolic dysfunction and heart failure in adults with myotonic dystrophy type 1. Am Heart J. 2010 Dec; 160(6):1137-41, 1141.e1. PMID: 21146669.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  154. Selke HM, Kimaiyo S, Sidle JE, Vedanthan R, Tierney WM, Shen C, Denski CD, Katschke AR, Wools-Kaloustian K. Task-shifting of antiretroviral delivery from health care workers to persons living with HIV/AIDS: clinical outcomes of a community-based program in Kenya. J Acquir Immune Defic Syndr. 2010 Dec; 55(4):483-90. PMID: 20683336.
    Citations: 79     Fields:    Translation:Humans
  155. Shen MJ, Choi EK, Tan AY, Han S, Shinohara T, Maruyama M, Chen LS, Shen C, Hwang C, Lin SF, Chen PS. Patterns of baseline autonomic nerve activity and the development of pacing-induced sustained atrial fibrillation. Heart Rhythm. 2011 Apr; 8(4):583-9. PMID: 21118728.
    Citations: 19     Fields:    Translation:Animals
  156. Jeong J, Li L, Liu Y, Nephew KP, Huang TH, Shen C. An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer. BMC Med Genomics. 2010 Nov 25; 3:55. PMID: 21108837.
    Citations: 6     Fields:    Translation:HumansCells
  157. Simonaitis L, Belsito A, Cravens G, Shen C, Overhage JM. Continuity of Care Document (CCD) Enables Delivery of Medication Histories to the Primary Care Clinician. AMIA Annu Symp Proc. 2010 Nov 13; 2010:747-51. PMID: 21347078.
    Citations: 4     Fields:    Translation:Humans
  158. Wang G, Wang Y, Shen C, Huang YW, Huang K, Huang TH, Nephew KP, Li L, Liu Y. RNA polymerase II binding patterns reveal genomic regions involved in microRNA gene regulation. PLoS One. 2010 Nov 02; 5(11):e13798. PMID: 21072189.
    Citations: 28     Fields:    Translation:HumansCells
  159. Fang F, Balch C, Schilder J, Breen T, Zhang S, Shen C, Li L, Kulesavage C, Snyder AJ, Nephew KP, Matei DE. A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer. Cancer. 2010 Sep 01; 116(17):4043-53. PMID: 20564122.
    Citations: 54     Fields:    Translation:HumansCellsCTClinical Trials
  160. Dubé MP, Shen C, Mather KJ, Waltz J, Greenwald M, Gupta SK. Relationship of body composition, metabolic status, antiretroviral use, and HIV disease factors to endothelial dysfunction in HIV-infected subjects. AIDS Res Hum Retroviruses. 2010 Aug; 26(8):847-54. PMID: 20673142.
    Citations: 6     Fields:    Translation:HumansCells
  161. Gökmen-Polar Y, Toroni RA, Hocevar BA, Badve S, Zhao Q, Shen C, Bruckheimer E, Kinch MS, Miller KD. Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer. Breast Cancer Res Treat. 2011 Jun; 127(2):375-84. PMID: 20602165.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  162. Braitstein P, Katshcke A, Shen C, Sang E, Nyandiko W, Ochieng VO, Vreeman R, Yiannoutsos CT, Wools-Kaloustian K, Ayaya S. Retention of HIV-infected and HIV-exposed children in a comprehensive HIV clinical care programme in Western Kenya. Trop Med Int Health. 2010 Jul; 15(7):833-41. PMID: 20487430.
    Citations: 21     Fields:    Translation:Humans
  163. Were MC, Emenyonu N, Achieng M, Shen C, Ssali J, Masaba JP, Tierney WM. Evaluating a scalable model for implementing electronic health records in resource-limited settings. J Am Med Inform Assoc. 2010 May-Jun; 17(3):237-44. PMID: 20442140.
    Citations: 14     Fields:    Translation:Humans
  164. Li L, Borges S, Jason RD, Shen C, Desta Z, Flockhart D. A penalized mixture model approach in genotype/phenotype association analysis for quantitative phenotypes. Cancer Inform. 2010 Apr 27; 9:93-103. PMID: 20467479.
    Citations: 1     
  165. Were MC, Shen C, Bwana M, Emenyonu N, Musinguzi N, Nkuyahaga F, Kembabazi A, Tierney WM. Creation and evaluation of EMR-based paper clinical summaries to support HIV-care in Uganda, Africa. Int J Med Inform. 2010 Feb; 79(2):90-6. PMID: 20036193.
    Citations: 16     Fields:    Translation:HumansCells
  166. Das MK, Michael MA, Suradi H, Peng J, Sinha A, Shen C, Mahenthiran J, Kovacs RJ. Usefulness of fragmented QRS on a 12-lead electrocardiogram in acute coronary syndrome for predicting mortality. Am J Cardiol. 2009 Dec 15; 104(12):1631-7. PMID: 19962466.
    Citations: 27     Fields:    Translation:Humans
  167. Shao M, Cao L, Shen C, Satpathy M, Chelladurai B, Bigsby RM, Nakshatri H, Matei D. Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase. Cancer Res. 2009 Dec 15; 69(24):9192-201. PMID: 19951993.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  168. Das MK, Maskoun W, Shen C, Michael MA, Suradi H, Desai M, Subbarao R, Bhakta D. Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy. Heart Rhythm. 2010 Jan; 7(1):74-80. PMID: 20129288.
    Citations: 37     Fields:    Translation:HumansPHPublic Health
  169. Okereke IC, Gangadharan SP, Kent MS, Nicotera SP, Shen C, DeCamp MM. Standard uptake value predicts survival in non-small cell lung cancer. Ann Thorac Surg. 2009 Sep; 88(3):911-5; discussion 915-6. PMID: 19699919.
    Citations: 5     Fields:    Translation:Humans
  170. Qin L, Weissfeld LA, Shen C, Levine MD. A Two-Latent-Class Model for Smoking Cessation Data with Informative Dropouts. Commun Stat Theory Methods. 2009 Sep 01; 38(15):2604-2619. PMID: 20523912.
    Citations:    
  171. Goldblatt EM, Gentry ER, Fox MJ, Gryaznov SM, Shen C, Herbert BS. The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel. Mol Cancer Ther. 2009 Jul; 8(7):2027-35. PMID: 19509275.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  172. Cao M, Liang Y, Shen C, Miller KD, Stantz KM. Developing DCE-CT to quantify intra-tumor heterogeneity in breast tumors with differing angiogenic phenotype. IEEE Trans Med Imaging. 2009 Jun; 28(6):861-71. PMID: 19150783.
    Citations: 10     Fields:    Translation:HumansAnimals
  173. Shen C, Sheng Q, Dai J, Li Y, Zeng R, Tang H. On the estimation of false positives in peptide identifications using decoy search strategy. Proteomics. 2009 Jan; 9(1):194-204. PMID: 19053142.
    Citations: 3     Fields:    
  174. Howard TJ, Browne JS, Zyromski NJ, Lavu H, Baker MS, Shen C, Madura JA. Mechanisms of primary operative failure and results of remedial operation in patients with chronic pancreatitis. J Gastrointest Surg. 2008 Dec; 12(12):2087-95; discussion 2095-6. PMID: 18846404.
    Citations: 4     Fields:    Translation:Humans
  175. Dubé MP, Shen C, Greenwald M, Mather KJ. No impairment of endothelial function or insulin sensitivity with 4 weeks of the HIV protease inhibitors atazanavir or lopinavir-ritonavir in healthy subjects without HIV infection: a placebo-controlled trial. Clin Infect Dis. 2008 Aug 15; 47(4):567-74. PMID: 18636958.
    Citations: 18     Fields:    Translation:Humans
  176. Das MK, Suradi H, Maskoun W, Michael MA, Shen C, Peng J, Dandamudi G, Mahenthiran J. Fragmented wide QRS on a 12-lead ECG: a sign of myocardial scar and poor prognosis. Circ Arrhythm Electrophysiol. 2008 Oct; 1(4):258-68. PMID: 19808417.
    Citations: 51     Fields:    Translation:Humans
  177. Saha S, Harrison SH, Shen C, Tang H, Radivojac P, Arnold RJ, Zhang X, Chen JY. HIP2: an online database of human plasma proteins from healthy individuals. BMC Med Genomics. 2008 Apr 25; 1:12. PMID: 18439290.
    Citations: 10     Fields:    
  178. Dodge HH, Shen C, Ganguli M. Application of the Pattern-Mixture Latent Trajectory Model in an Epidemiological Study with Non-Ignorable Missingness. J Data Sci. 2008 Apr 01; 6(2):247-259. PMID: 20401339.
    Citations: 9     
  179. Dubé MP, Gorski JC, Shen C. Severe impairment of endothelial function with the HIV-1 protease inhibitor indinavir is not mediated by insulin resistance in healthy subjects. Cardiovasc Toxicol. 2008 Mar; 8(1):15-22. PMID: 18172783.
    Citations: 7     Fields:    Translation:Humans
  180. Li L, Yu M, Jason RD, Shen C, Azzouz F, McLeod HL, Borges-Gonzales S, Nguyen A, Skaar T, Desta Z, Sweeney CJ, Flockhart DA. A mixture model approach in gene-gene and gene-environmental interactions for binary phenotypes. J Biopharm Stat. 2008; 18(6):1150-77. PMID: 18991114.
    Citations: 3     Fields:    Translation:Humans
  181. Wang X, Wang G, Shen C, Li L, Wang X, Mooney SD, Edenberg HJ, Sanford JR, Liu Y. Using RNase sequence specificity to refine the identification of RNA-protein binding regions. BMC Genomics. 2008; 9 Suppl 1:S17. PMID: 18366606.
    Citations: 4     Fields:    Translation:Cells
  182. Lavu H, Knuth JL, Baker MS, Shen C, Zyromski NJ, Schmidt M, Nakeeb A, Howard TJ. Middle segment pancreatectomy can be safely incorporated into a pancreatic surgeon's clinical practice. HPB (Oxford). 2008; 10(6):491-7. PMID: 19088938.
    Citations: 9     Fields:    
  183. Shen C, Breen TE, Dobrolecki LE, Schmidt CM, Sledge GW, Miller KD, Hickey RJ. Comparison of computational algorithms for the classification of liver cancer using SELDI mass spectrometry: a case study. Cancer Inform. 2007 Dec 11; 3:329-39. PMID: 19455252.
    Citations: 2     
  184. Shen C, Wang Z, Shankar G, Zhang X, Li L. A hierarchical statistical model to assess the confidence of peptides and proteins inferred from tandem mass spectrometry. Bioinformatics. 2008 Jan 15; 24(2):202-8. PMID: 18024968.
    Citations: 15     Fields:    
  185. Chen JY, Yan Z, Shen C, Fitzpatrick DP, Wang M. A systems biology approach to the study of cisplatin drug resistance in ovarian cancers. J Bioinform Comput Biol. 2007 Apr; 5(2a):383-405. PMID: 17589967.
    Citations: 7     Fields:    Translation:HumansCells
  186. Shen C, Gao S. A mixed-effects model for cognitive decline with non-monotone non-response from a two-phase longitudinal study of dementia. Stat Med. 2007 Jan 30; 26(2):409-25. PMID: 16345034.
    Citations: 4     Fields:    Translation:Humans
  187. Kirkman MS, Shankar RR, Shankar S, Shen C, Brizendine E, Baron A, McGill J. Treating postprandial hyperglycemia does not appear to delay progression of early type 2 diabetes: the Early Diabetes Intervention Program. Diabetes Care. 2006 Sep; 29(9):2095-101. PMID: 16936159.
    Citations: 9     Fields:    Translation:Humans
  188. Shen C, Li L, Chen JY. A statistical framework to discover true associations from multiprotein complex pull-down proteomics data sets. Proteins. 2006 Aug 01; 64(2):436-43. PMID: 16705649.
    Citations:    Fields:    Translation:AnimalsCells
  189. Shen C, Weissfeld L. A copula model for repeated measurements with non-ignorable non-monotone missing outcome. Stat Med. 2006 Jul 30; 25(14):2427-40. PMID: 16143999.
    Citations: 2     Fields:    Translation:Humans
  190. Chen JY, Shen C, Sivachenko AY. Mining Alzheimer disease relevant proteins from integrated protein interactome data. Pac Symp Biocomput. 2006; 367-78. PMID: 17094253.
    Citations: 45     Fields:    Translation:Humans
  191. Chen JY, Shen C, Yan Z, Brown DP, Wang M. A systems biology case study of ovarian cancer drug resistance. Comput Syst Bioinformatics Conf. 2006; 389-98. PMID: 17369659.
    Citations: 7     Fields:    Translation:Humans
  192. Ganguli M, Dodge HH, Shen C, Pandav RS, DeKosky ST. Alzheimer disease and mortality: a 15-year epidemiological study. Arch Neurol. 2005 May; 62(5):779-84. PMID: 15883266.
    Citations: 35     Fields:    Translation:Humans
  193. Shen C, Weissfeld L. Application of pattern-mixture models to outcomes that are potentially missing not at random using pseudo maximum likelihood estimation. Biostatistics. 2005 Apr; 6(2):333-47. PMID: 15772110.
    Citations: 3     Fields:    Translation:Humans
  194. Shen C, Li L, Chen JY. Discover true association rates in multi-protein complex proteomics data sets. Proc IEEE Comput Syst Bioinform Conf. 2005; 167-74. PMID: 16447974.
    Citations: 1     Fields:    Translation:AnimalsCells
  195. Ganguli M, Dodge HH, Shen C, DeKosky ST. Mild cognitive impairment, amnestic type: an epidemiologic study. Neurology. 2004 Jul 13; 63(1):115-21. PMID: 15249620.
    Citations: 136     Fields:    Translation:Humans
  196. Bharucha AJ, Pandav R, Shen C, Dodge HH, Ganguli M. Predictors of nursing facility admission: a 12-year epidemiological study in the United States. J Am Geriatr Soc. 2004 Mar; 52(3):434-9. PMID: 14962161.
    Citations: 29     Fields:    Translation:Humans
  197. Dodge HH, Shen C, Pandav R, DeKosky ST, Ganguli M. Functional transitions and active life expectancy associated with Alzheimer disease. Arch Neurol. 2003 Feb; 60(2):253-9. PMID: 12580712.
    Citations: 13     Fields:    Translation:Humans
  198. Mulsant BH, Pollock BG, Kirshner M, Shen C, Dodge H, Ganguli M. Serum anticholinergic activity in a community-based sample of older adults: relationship with cognitive performance. Arch Gen Psychiatry. 2003 Feb; 60(2):198-203. PMID: 12578438.
    Citations: 59     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.