Harvard Catalyst Profiles

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Sven Kratochvil, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Melzi E, Willis JR, Ma KM, Lin YC, Kratochvil S, Berndsen ZT, Landais EA, Kalyuzhniy O, Nair U, Warner J, Steichen JM, Kalyuzhniy A, Le A, Pecetta S, Perez M, Kirsch K, Weldon SR, Falcone S, Himansu S, Carfi A, Sok D, Ward AB, Schief WR, Batista FD. Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice. Immunity. 2022 Nov 08; 55(11):2168-2186.e6. PMID: 36179690; PMCID: PMC9671093.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. Lemke MM, Theisen RM, Bozich ER, McLean MR, Lee CY, Lopez E, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kratochvil S, Wines BD, Hogarth PM, Kent SJ, Chung AW, Arnold KB. A Quantitative Approach to Unravel the Role of Host Genetics in IgG-Fc?R Complex Formation After Vaccination. Front Immunol. 2022; 13:820148. PMID: 35273603; PMCID: PMC8902241.
    Citations:    Fields:    Translation:HumansPHPublic Health
  3. Pecetta S, Kratochvil S, Kato Y, Vadivelu K, Rappuoli R. Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines. Pharmacol Rev. 2022 01; 74(1):313-339. PMID: 35101964.
    Citations:    Fields:    Translation:HumansCells
  4. Kratochvil S, Shen CH, Lin YC, Xu K, Nair U, Da Silva Pereira L, Tripathi P, Arnold J, Chuang GY, Melzi E, Schön A, Zhang B, Dillon M, Bonilla B, Flynn BJ, Kirsch KH, Kisalu NK, Kiyuka PK, Liu T, Ou L, Pancera M, Rawi R, Reveiz M, Seignon K, Wang LT, Waring MT, Warner J, Yang Y, Francica JR, Idris AH, Seder RA, Kwong PD, Batista FD. Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity. 2021 12 14; 54(12):2859-2876.e7. PMID: 34788599; PMCID: PMC9087378.
    Citations: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  5. Lemke MM, McLean MR, Lee CY, Lopez E, Bozich ER, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Kratochvil S, Wines BD, Hogarth PM, Kent SJ, Chung AW, Arnold KB. A systems approach to elucidate personalized mechanistic complexities of antibody-Fc receptor activation post-vaccination. Cell Rep Med. 2021 09 21; 2(9):100386. PMID: 34622227; PMCID: PMC8484512.
    Citations: 3     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  6. Wang X, Ray R, Kratochvil S, Melzi E, Lin YC, Giguere S, Xu L, Warner J, Cheon D, Liguori A, Groschel B, Phelps N, Adachi Y, Tingle R, Wu L, Crotty S, Kirsch KH, Nair U, Schief WR, Batista FD. Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors. EMBO J. 2021 01 15; 40(2):e105926. PMID: 33258500.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  7. Aldon Y, Kratochvil S, Shattock RJ, McKay PF. Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non-Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae. J Immunol. 2020 02 15; 204(4):903-913. PMID: 31915263; PMCID: PMC6994839.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  8. Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science. 2019 12 06; 366(6470). PMID: 31672916.
    Citations: 76     Fields:    Translation:HumansAnimalsCells
  9. Cheeseman HM, Day S, McFarlane LR, Fleck S, Miller A, Cole T, Sousa-Santos N, Cope A, Cizmeci D, Tolazzi M, Hwekwete E, Hannaman D, Kratochvil S, McKay PF, Chung AW, Kent SJ, Cook A, Scarlatti G, Abraham S, Combadiere B, McCormack S, Lewis DJ, Shattock RJ. Combined Skin and Muscle DNA Priming Provides Enhanced Humoral Responses to a Human Immunodeficency Virus Type 1 Clade C Envelope Vaccine. Hum Gene Ther. 2018 09; 29(9):1011-1028. PMID: 30027768.
    Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic HealthCTClinical Trials
  10. Lin YC, Pecetta S, Steichen JM, Kratochvil S, Melzi E, Arnold J, Dougan SK, Wu L, Kirsch KH, Nair U, Schief WR, Batista FD. One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice. EMBO J. 2018 09 14; 37(18). PMID: 30087111; PMCID: PMC6138433.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  11. Kratochvil S, McKay PF, Chung AW, Kent SJ, Gilmour J, Shattock RJ. Corrigendum: Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination. Front Immunol. 2018; 9:342. PMID: 29508861.
    Citations:    Fields:    
  12. Anderson J, Olafsdottir TA, Kratochvil S, McKay PF, Östensson M, Persson J, Shattock RJ, Harandi AM. Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans. Front Immunol. 2018; 9:301. PMID: 29535712.
    Citations: 9     Fields:    Translation:HumansCells
  13. Kratochvil S, McKay PF, Chung AW, Kent SJ, Gilmour J, Shattock RJ. Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination. Front Immunol. 2017; 8:1883. PMID: 29326728.
    Citations: 9     Fields:    
  14. Pinder CL, Kratochvil S, Cizmeci D, Muir L, Guo Y, Shattock RJ, McKay PF. Isolation and Characterization of Antigen-Specific Plasmablasts Using a Novel Flow Cytometry-Based Ig Capture Assay. J Immunol. 2017 12 15; 199(12):4180-4188. PMID: 29118244; PMCID: PMC5720343.
    Citations: 11     Fields:    Translation:HumansCellsPHPublic Health
  15. Muir L, McKay PF, Petrova VN, Klymenko OV, Kratochvil S, Pinder CL, Kellam P, Shattock RJ. Optimisation of ex vivo memory B cell expansion/differentiation for interrogation of rare peripheral memory B cell subset responses. Wellcome Open Res. 2017; 2:97. PMID: 29588920.
    Citations: 4     
  16. Kratochvil S, McKay PF, Kopycinski JT, Bishop C, Hayes PJ, Muir L, Pinder CL, Cizmeci D, King D, Aldon Y, Wines BD, Hogarth PM, Chung AW, Kent SJ, Held K, Geldmacher C, Dally L, Santos NS, Cole T, Gilmour J, Fidler S, Shattock RJ. A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens. Front Immunol. 2017; 8:595. PMID: 28596770.
    Citations: 12     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.