Harvard Catalyst Profiles

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David Lawrence Mayhew, M.D., Ph.D.


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  1. F30AG031623 (MAYHEW, DAVID L.) Nov 1, 2007 - Oct 31, 2010
    Mechanisms of Skeletal Muscle Satellite Cell Regulation in Aging
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. So J, Mabe NW, Englinger B, Chow KH, Moyer SM, Yerrum S, Trissal MC, Marques JG, Kwon JJ, Shim B, Pal S, Panditharatna E, Quinn T, Schaefer DA, Jeong D, Mayhew DL, Hwang J, Beroukhim R, Ligon KL, Stegmaier K, Filbin MG, Hahn WC. VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system. JCI Insight. 2022 10 10; 7(19). PMID: 36040810; PMCID: PMC9675470.
    Citations:    Fields:    Translation:HumansCells
  2. Kwon JJ, Hajian B, Bian Y, Young LC, Amor AJ, Fuller JR, Fraley CV, Sykes AM, So J, Pan J, Baker L, Lee SJ, Wheeler DB, Mayhew DL, Persky NS, Yang X, Root DE, Barsotti AM, Stamford AW, Perry CK, Burgin A, McCormick F, Lemke CT, Hahn WC, Aguirre AJ. Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Nature. 2022 09; 609(7926):408-415. PMID: 35831509; PMCID: PMC9694338.
    Citations:    Fields:    
  3. Bekele RT, Samant AS, Nassar AH, So J, Garcia EP, Curran CR, Hwang JH, Mayhew DL, Nag A, Thorner AR, Börcsök J, Sztupinszki Z, Pan CX, Bellmunt J, Kwiatkowski DJ, Sonpavde GP, Van Allen EM, Mouw KW. RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics. J Clin Invest. 2021 11 15; 131(22). PMID: 34554931; PMCID: PMC8592548.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  4. Blitzer GC, Parekh AD, Chen S, Taparra K, Kahn JM, Fields EC, Stahl JM, Rosenberg SA, Buatti JM, Laucis AM, Wang Y, Mayhew DL, McDonald AM, Harari PM, Brower JV. Why an Increasing Number of Unmatched Residency Positions in Radiation Oncology? A Survey of Fourth-Year Medical Students. Adv Radiat Oncol. 2021 Sep-Oct; 6(5):100743. PMID: 34466713; PMCID: PMC8385400.
  5. Richter C, Mayhew D, Rennhack JP, So J, Stover EH, Hwang JH, Szczesna-Cordary D. Genomic Amplification and Functional Dependency of the Gamma Actin Gene ACTG1 in Uterine Cancer. Int J Mol Sci. 2020 Nov 18; 21(22). PMID: 33217970.
    Citations: 8     Fields:    Translation:HumansCells
  6. Roberts BM, Lavin KM, Many GM, Thalacker-Mercer A, Merritt EK, Bickel CS, Mayhew DL, Tuggle SC, Cross JM, Kosek DJ, Petrella JK, Brown CJ, Hunter GR, Windham ST, Allman RM, Bamman MM. Human neuromuscular aging: Sex differences revealed at the myocellular level. Exp Gerontol. 2018 06; 106:116-124. PMID: 29481967.
    Citations: 21     Fields:    Translation:HumansCells
  7. Ramirez-Fort MK, Zeng J, Feily A, Ramirez-Pacheco LA, Jenrette JM, Mayhew DL, Syed T, Cooper SL, Linden C, Graybill WS, French LE, Lange CS. Radiotherapy-induced reactivation of neurotrophic human herpes viruses: Overview and management. J Clin Virol. 2018 01; 98:18-27. PMID: 29197712.
    Citations: 14     Fields:    Translation:HumansCells
  8. Stec MJ, Thalacker-Mercer A, Mayhew DL, Kelly NA, Tuggle SC, Merritt EK, Brown CJ, Windham ST, Dell'Italia LJ, Bickel CS, Roberts BM, Vaughn KM, Isakova-Donahue I, Many GM, Bamman MM. Randomized, four-arm, dose-response clinical trial to optimize resistance exercise training for older adults with age-related muscle atrophy. Exp Gerontol. 2017 12 01; 99:98-109. PMID: 28964826; PMCID: PMC5765758.
    Citations: 27     Fields:    Translation:Humans
  9. McDonald AM, Swain TA, Mayhew DL, Cardan RA, Baker CB, Harris DM, Yang ES, Fiveash JB. CT Measures of Bone Mineral Density and Muscle Mass Can Be Used to Predict Noncancer Death in Men with Prostate Cancer. Radiology. 2017 Feb; 282(2):475-483. PMID: 27598538.
    Citations: 17     Fields:    Translation:Humans
  10. Olivry T, Mayhew D, Paps JS, Linder KE, Peredo C, Rajpal D, Hofland H, Cote-Sierra J. Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions. J Invest Dermatol. 2016 10; 136(10):1961-1969. PMID: 27342734.
    Citations: 25     Fields:    Translation:AnimalsCells
  11. McDonald AM, Jones JA, Cardan RA, Saag KS, Mayhew DL, Fiveash JB. Combining Computed Tomography-Based Bone Density Assessment with FRAX Screening in Men with Prostate Cancer. J Clin Densitom. 2016 10; 19(4):430-435. PMID: 27241940.
    Citations: 4     Fields:    Translation:Humans
  12. Stec MJ, Mayhew DL, Bamman MM. The effects of age and resistance loading on skeletal muscle ribosome biogenesis. J Appl Physiol (1985). 2015 Oct 15; 119(8):851-7. PMID: 26294750; PMCID: PMC4747892.
    Citations: 32     Fields:    Translation:HumansCells
  13. Danilchanka O, Sun J, Pavlenok M, Maueröder C, Speer A, Siroy A, Marrero J, Trujillo C, Mayhew DL, Doornbos KS, Muñoz LE, Herrmann M, Ehrt S, Berens C, Niederweis M. An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity. Proc Natl Acad Sci U S A. 2014 May 06; 111(18):6750-5. PMID: 24753609.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  14. Goodman CA, Mayhew DL, Hornberger TA. Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass. Cell Signal. 2011 Dec; 23(12):1896-906. PMID: 21821120; PMCID: PMC3744211.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  15. Mayhew DL, Hornberger TA, Lincoln HC, Bamman MM. Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy. J Physiol. 2011 Jun 15; 589(Pt 12):3023-37. PMID: 21486778.
    Citations: 39     Fields:    Translation:AnimalsCells
  16. Mayhew DL, Kim JS, Cross JM, Ferrando AA, Bamman MM. Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans. J Appl Physiol (1985). 2009 Nov; 107(5):1655-62. PMID: 19589955.
    Citations: 93     Fields:    Translation:HumansCells
  17. Petrella JK, Kim JS, Mayhew DL, Cross JM, Bamman MM. Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis. J Appl Physiol (1985). 2008 Jun; 104(6):1736-42. PMID: 18436694.
    Citations: 163     Fields:    Translation:HumansCells
  18. Benos DJ, Bashari E, Chaves JM, Gaggar A, Kapoor N, LaFrance M, Mans R, Mayhew D, McGowan S, Polter A, Qadri Y, Sarfare S, Schultz K, Splittgerber R, Stephenson J, Tower C, Walton RG, Zotov A. The ups and downs of peer review. Adv Physiol Educ. 2007 Jun; 31(2):145-52. PMID: 17562902.
    Citations: 34     Fields:    Translation:Humans
  19. Bamman MM, Petrella JK, Kim JS, Mayhew DL, Cross JM. Cluster analysis tests the importance of myogenic gene expression during myofiber hypertrophy in humans. J Appl Physiol (1985). 2007 Jun; 102(6):2232-9. PMID: 17395765.
    Citations: 70     Fields:    Translation:Humans
  20. Mayhew DL, Thyfault JP, Koch AJ. Rest-interval length affects leukocyte levels during heavy resistance exercise. J Strength Cond Res. 2005 Feb; 19(1):16-22. PMID: 15705028.
    Citations: 12     Fields:    Translation:HumansCells
  21. Mayhew DL, Mayhew JL, Ware JS. Effects of long-term creatine supplementation on liver and kidney functions in American college football players. Int J Sport Nutr Exerc Metab. 2002 Dec; 12(4):453-60. PMID: 12500988.
    Citations: 9     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.