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Beth Elinda Zucconi, Ph.D.

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  1. K99GM124357 (ZUCCONI, BETH) Aug 1, 2017 - Jul 31, 2019
    NIH/NIGMS
    p300/CBP and MOZ Acetyltransferase Function and Substrate Selectivity
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zucconi BE, Makofske JL, Meyers DJ, Hwang Y, Wu M, Kuroda MI, Cole PA. Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP. Biochemistry. 2019 Apr 23; 58(16):2133-2143. PMID: 30924641.
    Citations:    
  2. Kim E, Zucconi BE, Wu M, Nocco SE, Meyers DJ, McGee JS, Venkatesh S, Cohen DL, Gonzalez EC, Ryu B, Cole PA, Alani RM. MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma. Cancer Res. 2019 Mar 25. PMID: 30910803.
    Citations:    
  3. Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Schölz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, Choudhary C. Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome. Cell. 2018 06 28; 174(1):231-244.e12. PMID: 29804834.
    Citations:    Fields:    
  4. Zucconi BE, Cole PA. Allosteric regulation of epigenetic modifying enzymes. Curr Opin Chem Biol. 2017 Aug; 39:109-115. PMID: 28689145.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  5. Zucconi BE, Luef B, Xu W, Henry RA, Nodelman IM, Bowman GD, Andrews AJ, Cole PA. Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112. Biochemistry. 2016 07 12; 55(27):3727-34. PMID: 27332697.
    Citations: 9     Fields:    Translation:HumansCells
  6. Shimberg GD, Michalek JL, Oluyadi AA, Rodrigues AV, Zucconi BE, Neu HM, Ghosh S, Sureschandra K, Wilson GM, Stemmler TL, Michel SL. Cleavage and polyadenylation specificity factor 30: An RNA-binding zinc-finger protein with an unexpected 2Fe-2S cluster. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4700-5. PMID: 27071088.
    Citations: 2     Fields:    Translation:HumansCells
  7. Yoon JH, Jo MH, White EJ, De S, Hafner M, Zucconi BE, Abdelmohsen K, Martindale JL, Yang X, Wood WH, Shin YM, Song JJ, Tuschl T, Becker KG, Wilson GM, Hohng S, Gorospe M. AUF1 promotes let-7b loading on Argonaute 2. Genes Dev. 2015 Aug 01; 29(15):1599-604. PMID: 26253535.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  8. Bordbar E, Taghipour M, Zucconi BE. Reliability of Different RBC Indices and Formulas in Discriminating between ß-Thalassemia Minor and other Microcytic Hypochromic Cases. Mediterr J Hematol Infect Dis. 2015; 7(1):e2015022. PMID: 25745549.
    Citations: 4     
  9. White MR, Khan MM, Deredge D, Ross CR, Quintyn R, Zucconi BE, Wysocki VH, Wintrode PL, Wilson GM, Garcin ED. A dimer interface mutation in glyceraldehyde 3-phosphate dehydrogenase regulates its binding to AU-rich RNA. J Biol Chem. 2015 Feb 13; 290(7):4129. PMID: 25681510.
    Citations: 1     Fields:    
  10. Wells ML, Washington OL, Hicks SN, Nobile CJ, Hartooni N, Wilson GM, Zucconi BE, Huang W, Li L, Fargo DC, Blackshear PJ. Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans. Mol Microbiol. 2015 Mar; 95(6):1036-53. PMID: 25524641.
    Citations: 10     Fields:    Translation:AnimalsCells
  11. White MR, Khan MM, Deredge D, Ross CR, Quintyn R, Zucconi BE, Wysocki VH, Wintrode PL, Wilson GM, Garcin ED. A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA. J Biol Chem. 2015 Jan 16; 290(3):1770-85. PMID: 25451934.
    Citations: 5     Fields:    Translation:HumansCells
  12. Zucconi BE, Wilson GM. Assembly of functional ribonucleoprotein complexes by AU-rich element RNA-binding protein 1 (AUF1) requires base-dependent and -independent RNA contacts. J Biol Chem. 2013 Sep 27; 288(39):28034-48. PMID: 23940053.
    Citations: 4     Fields:    Translation:HumansCells
  13. Wu X, Chesoni S, Rondeau G, Tempesta C, Patel R, Charles S, Daginawala N, Zucconi BE, Kishor A, Xu G, Shi Y, Li ML, Irizarry-Barreto P, Welsh J, Wilson GM, Brewer G. Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs. Nucleic Acids Res. 2013 Feb 01; 41(4):2644-58. PMID: 23303783.
    Citations: 19     Fields:    Translation:HumansCells
  14. Kedar VP, Zucconi BE, Wilson GM, Blackshear PJ. Direct binding of specific AUF1 isoforms to tandem zinc finger domains of tristetraprolin (TTP) family proteins. J Biol Chem. 2012 Feb 17; 287(8):5459-71. PMID: 22203679.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  15. Zucconi BE, Wilson GM. Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed). 2011 Jun 01; 16:2307-25. PMID: 21622178.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  16. Zucconi BE, Ballin JD, Brewer BY, Ross CR, Huang J, Toth EA, Wilson GM. Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands. J Biol Chem. 2010 Dec 10; 285(50):39127-39. PMID: 20926381.
    Citations: 32     Fields:    Translation:HumansCells
  17. Mayo DJ, Turner DP, Zucconi BE, Predecki AH. DNA cleavage by photolysis of aryl sulfoxides. Bioorg Med Chem Lett. 2007 Nov 15; 17(22):6116-8. PMID: 17904368.
    Citations:    Fields:    Translation:Cells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.