Harvard Catalyst Profiles

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Gavin Reinhardt Schnitzler, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21HL107964 (SCHNITZLER, GAVIN R.) Jan 1, 2012 - Nov 30, 2013
    NIH/NHLBI
    Mechanisms of vascular-specific gene regulation by estrogen
    Role: Principal Investigator
  2. R21DA027747 (SCHNITZLER, GAVIN R) Sep 1, 2009 - Aug 31, 2011
    NIH/NIDA
    Does the extreme variability of methadone metabolism have an epigenetic cause?
    Role: Principal Investigator
  3. R21DK079300 (SCHNITZLER, GAVIN R) Aug 1, 2007 - Jul 31, 2010
    NIH/NIDDK
    Do chromatin changes control polymorphic expression of drug metabolizing genes?
    Role: Principal Investigator
  4. K01CA088835 (SCHNITZLER, GAVIN R) Apr 1, 2000 - Mar 31, 2005
    NIH/NCI
    ROLE OF CHROMATIN REMODELING IN GROWTH CONTROL
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Esposito ML, Zhang Y, Qiao X, Reyelt L, Paruchuri V, Schnitzler GR, Morine KJ, Annamalai SK, Bogins C, Natov PS, Pedicini R, Breton C, Mullin A, Mackey EE, Patel A, Rowin E, Jaffe IZ, Karas RH, Kapur NK. Left Ventricular Unloading Before Reperfusion Promotes Functional Recovery After Acute Myocardial Infarction. J Am Coll Cardiol. 2018 Jul 31; 72(5):501-514. PMID: 30049311.
    Citations:    Fields:    
  2. Lu Q, Schnitzler GR, Vallaster CS, Ueda K, Erdkamp S, Briggs CE, Iyer LK, Jaffe IZ, Karas RH. Unliganded estrogen receptor alpha regulates vascular cell function and gene expression. Mol Cell Endocrinol. 2017 02 15; 442:12-23. PMID: 27888004.
    Citations: 2     Fields:    Translation:AnimalsCells
  3. Zhao J, Schnitzler GR, Iyer LK, Aronovitz MJ, Baur WE, Karas RH. MicroRNA-Offset RNA Alters Gene Expression and Cell Proliferation. PLoS One. 2016; 11(6):e0156772. PMID: 27276022.
    Citations: 5     Fields:    Translation:AnimalsCells
  4. Lu Q, Schnitzler GR, Ueda K, Iyer LK, Diomede OI, Andrade T, Karas RH. ER Alpha Rapid Signaling Is Required for Estrogen Induced Proliferation and Migration of Vascular Endothelial Cells. PLoS One. 2016; 11(4):e0152807. PMID: 27035664.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  5. Richardson K, Schnitzler GR, Lai CQ, Ordovas JM. Functional Genomics Analysis of Big Data Identifies Novel Peroxisome Proliferator-Activated Receptor ? Target Single Nucleotide Polymorphisms Showing Association With Cardiometabolic Outcomes. Circ Cardiovasc Genet. 2015 Dec; 8(6):842-51. PMID: 26518621.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  6. Gordon FK, Vallaster CS, Westerling T, Iyer LK, Brown M, Schnitzler GR. Research resource: Aorta- and liver-specific ERa-binding patterns and gene regulation by estrogen. Mol Endocrinol. 2014 Aug; 28(8):1337-51. PMID: 24992180.
    Citations: 5     Fields:    Translation:AnimalsCells
  7. Bernelot Moens SJ, Schnitzler GR, Nickerson M, Guo H, Ueda K, Lu Q, Aronovitz MJ, Nickerson H, Baur WE, Hansen U, Iyer LK, Karas RH. Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury. Circulation. 2012 Oct 16; 126(16):1993-2004. PMID: 22997253.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  8. Sims HI, Pham CD, Schnitzler GR. Mapping assembly favored and remodeled nucleosome positions on polynucleosomal templates. Methods Mol Biol. 2012; 833:311-36. PMID: 22183602.
    Citations:    Fields:    Translation:HumansCells
  9. Pham CD, Sims HI, Archer TK, Schnitzler GR. Multiple distinct stimuli increase measured nucleosome occupancy around human promoters. PLoS One. 2011; 6(8):e23490. PMID: 21853138.
    Citations: 3     Fields:    Translation:HumansCells
  10. Denis GV, Nikolajczyk BS, Schnitzler GR. An emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis. FEBS Lett. 2010 Aug 04; 584(15):3260-8. PMID: 20493850.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  11. Pham CD, He X, Schnitzler GR. Divergent human remodeling complexes remove nucleosomes from strong positioning sequences. Nucleic Acids Res. 2010 Jan; 38(2):400-13. PMID: 19906705.
    Citations: 6     Fields:    Translation:HumansCells
  12. Neuman NA, Ma S, Schnitzler GR, Zhu Y, Lagna G, Hata A. The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone. J Biol Chem. 2009 May 08; 284(19):13202-12. PMID: 19265191.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  13. Wan M, Zhang J, Lai D, Jani A, Prestone-Hurlburt P, Zhao L, Ramachandran A, Schnitzler GR, Chi T. Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex. Eur J Immunol. 2009 Feb; 39(2):580-8. PMID: 19180471.
    Citations: 12     Fields:    Translation:AnimalsCells
  14. Sims HI, Baughman CB, Schnitzler GR. Human SWI/SNF directs sequence-specific chromatin changes on promoter polynucleosomes. Nucleic Acids Res. 2008 Nov; 36(19):6118-31. PMID: 18820294.
    Citations: 9     Fields:    Translation:HumansCells
  15. Schnitzler GR. Control of nucleosome positions by DNA sequence and remodeling machines. Cell Biochem Biophys. 2008; 51(2-3):67-80. PMID: 18543113.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  16. Sims HI, Lane JM, Ulyanova NP, Schnitzler GR. Human SWI/SNF drives sequence-directed repositioning of nucleosomes on C-myc promoter DNA minicircles. Biochemistry. 2007 Oct 09; 46(40):11377-88. PMID: 17877373.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  17. Ulyanova NP, Schnitzler GR. Inverted factor access and slow reversion characterize SWI/SNF-altered nucleosome dimers. J Biol Chem. 2007 Jan 12; 282(2):1018-28. PMID: 17121825.
    Citations: 8     Fields:    Translation:HumansCells
  18. Ulyanova NP, Schnitzler GR. Human SWI/SNF generates abundant, structurally altered dinucleosomes on polynucleosomal templates. Mol Cell Biol. 2005 Dec; 25(24):11156-70. PMID: 16314535.
    Citations: 25     Fields:    Translation:HumansCells
  19. Ramachandran A, Omar M, Cheslock P, Schnitzler GR. Linker histone H1 modulates nucleosome remodeling by human SWI/SNF. J Biol Chem. 2003 Dec 05; 278(49):48590-601. PMID: 14512420.
    Citations: 17     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.