Harvard Catalyst Profiles

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Mark Wade, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wade M, Fox NA, Zeanah CH, Nelson CA. Long-term effects of institutional rearing, foster care, and brain activity on memory and executive functioning. Proc Natl Acad Sci U S A. 2019 Jan 29; 116(5):1808-1813. PMID: 30642973.
    Citations:    Fields:    
  2. Wade M, Prime H, Jenkins JM, Yeates KO, Williams T, Lee K. On the relation between theory of mind and executive functioning: A developmental cognitive neuroscience perspective. Psychon Bull Rev. 2018 Dec; 25(6):2119-2140. PMID: 29619648.
    Citations:    Fields:    Translation:Humans
  3. Wade M, Fox NA, Zeanah CH, Nelson CA. Effect of Foster Care Intervention on Trajectories of General and Specific Psychopathology Among Children With Histories of Institutional Rearing: A Randomized Clinical Trial. JAMA Psychiatry. 2018 Nov 01; 75(11):1137-1145. PMID: 30267045.
  4. Browne DT, Wade M, Plamondon A, Leckie G, Perlman M, Madigan S, Jenkins JM. Child and contextual effects in the emergence of differential maternal sensitivity across siblings. Dev Psychol. 2018 Jul; 54(7):1265-1276. PMID: 29658742.
    Citations:    Fields:    Translation:Humans
  5. Wade M, Madigan S, Plamondon A, Rodrigues M, Browne D, Jenkins JM. Cumulative psychosocial risk, parental socialization, and child cognitive functioning: A longitudinal cascade model. Dev Psychol. 2018 06; 54(6):1038-1050. PMID: 29265828.
    Citations:    Fields:    Translation:Humans
  6. Madigan S, Wade M, Plamondon A, Maguire JL, Jenkins JM. Maternal Adverse Childhood Experience and Infant Health: Biomedical and Psychosocial Risks as Intermediary Mechanisms. J Pediatr. 2017 08; 187:282-289.e1. PMID: 28549634.
    Citations:    Fields:    Translation:Humans
  7. Wade M, Prime H, Hoffmann TJ, Schmidt LA, O'Connor TG, Jenkins JM. Birth weight interacts with a functional variant of the oxytocin receptor gene (OXTR) to predict executive functioning in children. Dev Psychopathol. 2018 02; 30(1):203-211. PMID: 28511728.
    Citations:    Fields:    Translation:Humans
  8. Madigan S, Wade M, Plamondon A, Jenkins JM. Trajectories of maternal depressive symptoms in the early childhood period and family-wide clustering of risk. J Affect Disord. 2017 06; 215:49-55. PMID: 28319691.
    Citations:    Fields:    Translation:Humans
  9. Madigan S, Wade M, Plamondon A, Jenkins JM. Neighborhood Collective Efficacy Moderates the Association between Maternal Adverse Childhood Experiences and Marital Conflict. Am J Community Psychol. 2016 06; 57(3-4):437-47. PMID: 27250904.
    Citations:    Fields:    Translation:Humans
  10. Wade M, Hoffmann TJ, Knafo-Noam A, O'Connor TG, Jenkins JM. Oxytocin and vasopressin hormone genes in children's externalizing problems: A cognitive endophenotype approach. Horm Behav. 2016 06; 82:78-86. PMID: 27155104.
    Citations:    Fields:    Translation:Humans
  11. Verhoef LG, Mattioli M, Ricci F, Li YC, Wade M. Multiplex detection of protein-protein interactions using a next generation luciferase reporter. Biochim Biophys Acta. 2016 Feb; 1863(2):284-92. PMID: 26646257.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  12. Adams CJ, Yu JS, Mao JH, Jen KY, Costes SV, Wade M, Shoemake J, Aina OH, Del Rosario R, Menchavez PT, Cardiff RD, Wahl GM, Balmain A. The Trp53 delta proline (Trp53?P) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development. Mol Carcinog. 2016 09; 55(9):1387-96. PMID: 26310697; PMCID: PMC4891300.
    Citations: 2     Fields:    Translation:AnimalsCells
  13. Wade M, Prime H, Madigan S. Using Sibling Designs to Understand Neurodevelopmental Disorders: From Genes and Environments to Prevention Programming. Biomed Res Int. 2015; 2015:672784. PMID: 26258141; PMCID: PMC4518166.
    Citations: 3     Fields:    Translation:Humans
  14. Madigan S, Wade M, Plamondon A, Browne D, Jenkins JM. Birth Weight Variability and Language Development: Risk, Resilience, and Responsive Parenting. J Pediatr Psychol. 2015 Oct; 40(9):869-77. PMID: 26112158.
    Citations: 5     Fields:    Translation:Humans
  15. Nahta R, Al-Mulla F, Al-Temaimi R, Amedei A, Andrade-Vieira R, Bay SN, Brown DG, Calaf GM, Castellino RC, Cohen-Solal KA, Colacci A, Cruickshanks N, Dent P, Di Fiore R, Forte S, Goldberg GS, Hamid RA, Krishnan H, Laird DW, Lasfar A, Marignani PA, Memeo L, Mondello C, Naus CC, Ponce-Cusi R, Raju J, Roy D, Roy R, Ryan EP, Salem HK, Scovassi AI, Singh N, Vaccari M, Vento R, Vondr√°cek J, Wade M, Woodrick J, Bisson WH. Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis. 2015 Jun; 36 Suppl 1:S2-18. PMID: 26106139.
    Citations: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  16. Wade M, Hoffmann TJ, Jenkins JM. Gene-environment interaction between the oxytocin receptor (OXTR) gene and parenting behaviour on children's theory of mind. Soc Cogn Affect Neurosci. 2015 Dec; 10(12):1749-57. PMID: 25977357; PMCID: PMC4666114.
    Citations: 3     Fields:    Translation:Humans
  17. Browne DT, Plamondon A, Prime H, Puente-Duran S, Wade M. Cumulative risk and developmental health: an argument for the importance of a family-wide science. Wiley Interdiscip Rev Cogn Sci. 2015 Jul-Aug; 6(4):397-407. PMID: 26263428.
    Citations:    Fields:    Translation:Humans
  18. Wade M, Browne DT, Plamondon A, Daniel E, Jenkins JM. Cumulative risk disparities in children's neurocognitive functioning: a developmental cascade model. Dev Sci. 2016 Mar; 19(2):179-94. PMID: 25845409.
    Citations:    Fields:    Translation:Humans
  19. Wade M, Madigan S, Akbari E, Jenkins JM. Cumulative biomedical risk and social cognition in the second year of life: prediction and moderation by responsive parenting. Front Psychol. 2015; 6:354. PMID: 25883576; PMCID: PMC4381485.
    Citations: 1     
  20. Madigan S, Wade M, Plamondon A, Jenkins J. Maternal abuse history, postpartum depression, and parenting: links with preschoolers' internalizing problems. Infant Ment Health J. 2015 Mar-Apr; 36(2):146-55. PMID: 25583550.
    Citations: 5     Fields:    Translation:Humans
  21. Wade M, Jenkins JM. Pregnancy hypertension and the risk for neuropsychological difficulties across early development: A brief report. Child Neuropsychol. 2016; 22(2):247-54. PMID: 25319507.
    Citations: 1     Fields:    Translation:Humans
  22. Prime H, Browne D, Akbari E, Wade M, Madigan S, Jenkins JM. The development of a measure of maternal cognitive sensitivity appropriate for use in primary care health settings. J Child Psychol Psychiatry. 2015 Apr; 56(4):488-95. PMID: 25185716.
    Citations: 1     Fields:    Translation:Humans
  23. Madigan S, Wade M, Tarabulsy G, Jenkins JM, Shouldice M. Association between abuse history and adolescent pregnancy: a meta-analysis. J Adolesc Health. 2014 Aug; 55(2):151-9. PMID: 25049043.
    Citations: 6     Fields:    Translation:Humans
  24. Wade M, Moore C, Astington JW, Frampton K, Jenkins JM. Cumulative contextual risk, maternal responsivity, and social cognition at 18 months. Dev Psychopathol. 2015 Feb; 27(1):189-203. PMID: 25017298.
    Citations: 2     Fields:    Translation:Humans
  25. Wade M, Hoffmann TJ, Jenkins JM. Association between the arginine vasopressin receptor 1A (AVPR1A) gene and preschoolers' executive functioning. Brain Cogn. 2014 Oct; 90:116-23. PMID: 25016245.
    Citations: 1     Fields:    Translation:Humans
  26. Madigan S, Wade M, Plamondon A, Vaillancourt K, Jenkins JM, Shouldice M, Benoit D. Course of depression and anxiety symptoms during the transition to parenthood for female adolescents with histories of victimization. Child Abuse Negl. 2014 Jul; 38(7):1160-70. PMID: 24862921.
    Citations: 6     Fields:    Translation:Humans
  27. Wade M, Li YC, Wahl GM. MDM2, MDMX and p53 in oncogenesis and cancer therapy. Nat Rev Cancer. 2013 Feb; 13(2):83-96. PMID: 23303139; PMCID: PMC4161369.
    Citations: 243     Fields:    Translation:HumansAnimals
  28. Bernal F, Wade M, Godes M, Davis TN, Whitehead DG, Kung AL, Wahl GM, Walensky LD. A stapled p53 helix overcomes HDMX-mediated suppression of p53. Cancer Cell. 2010 Nov 16; 18(5):411-22. PMID: 21075307.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  29. Wade M, Wang YV, Wahl GM. The p53 orchestra: Mdm2 and Mdmx set the tone. Trends Cell Biol. 2010 May; 20(5):299-309. PMID: 20172729; PMCID: PMC2910097.
    Citations: 170     Fields:    Translation:HumansAnimalsCells
  30. Wang YV, Wade M, Wahl GM. Guarding the guardian: Mdmx plays important roles in setting p53 basal activity and determining biological responses in vivo. Cell Cycle. 2009 Nov 01; 8(21):3443-4. PMID: 19838055; PMCID: PMC2777705.
    Citations: 4     Fields:    Translation:AnimalsCells
  31. Wang YV, Leblanc M, Wade M, Jochemsen AG, Wahl GM. Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases. Cancer Cell. 2009 Jul 07; 16(1):33-43. PMID: 19573810; PMCID: PMC2758524.
    Citations: 49     Fields:    Translation:AnimalsCells
  32. Wade M, Wahl GM. Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry? Mol Cancer Res. 2009 Jan; 7(1):1-11. PMID: 19147532; PMCID: PMC2629357.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  33. Wade M, Rodewald LW, Espinosa JM, Wahl GM. BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death. Cell Cycle. 2008 Jul 01; 7(13):1973-82. PMID: 18604177; PMCID: PMC2625302.
    Citations: 26     Fields:    Translation:HumansCells
  34. Wang YV, Wade M, Wong E, Li YC, Rodewald LW, Wahl GM. Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12365-70. PMID: 17640893; PMCID: PMC1941475.
    Citations: 50     Fields:    Translation:HumansCells
  35. Wade M, Wong ET, Tang M, Stommel JM, Wahl GM. Hdmx modulates the outcome of p53 activation in human tumor cells. J Biol Chem. 2006 Nov 03; 281(44):33036-44. PMID: 16905769.
    Citations: 64     Fields:    Translation:HumansCells
  36. Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, Wahl GM. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell. 2002 May; 9(5):1031-44. PMID: 12049739.
    Citations: 270     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.