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Ik-Kyung Jang, PH.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Libby P, Pasterkamp G, Crea F, Jang IK. Reassessing the Mechanisms of Acute Coronary Syndromes. Circ Res. 2019 Jan 04; 124(1):150-160. PMID: 30605419.
    Citations:    Fields:    
  2. Bryniarski KL, Yamamoto E, Sugiyama T, Xing L, Lee H, Jang IK. Differences in coronary plaque morphology between East Asian and Western White patients: an optical coherence tomography study. Coron Artery Dis. 2018 Nov; 29(7):597-602. PMID: 30020113.
    Citations:    Fields:    
  3. Yamamoto E, Thondapu V, Poon E, Sugiyama T, Fracassi F, Dijkstra J, Lee H, Ooi A, Barlis P, Jang IK. Endothelial Shear Stress and Plaque Erosion: A Computational Fluid Dynamics and Optical Coherence Tomography Study. JACC Cardiovasc Imaging. 2019 Feb; 12(2):374-375. PMID: 30343069.
    Citations:    Fields:    
  4. Duvjir G, Choi BK, Jang I, Ulstrup S, Kang S, Thi Ly T, Kim S, Choi YH, Jozwiak C, Bostwick A, Rotenberg E, Park JG, Sankar R, Kim KS, Kim J, Chang YJ. Emergence of a Metal-Insulator Transition and High-Temperature Charge-Density Waves in VSe2 at the Monolayer Limit. Nano Lett. 2018 Aug 02. PMID: 30063833.
    Citations:    Fields:    
  5. Al-Bawardy R, Thomas S, Cameron D, Jang IK. An accidentally crushed stent identified by optical coherence tomography. Coron Artery Dis. 2018 Aug; 29(5):438-440. PMID: 29649070.
    Citations:    Fields:    
  6. Sugiyama T, Yamamoto E, Bryniarski K, Xing L, Fracassi F, Lee H, Jang IK. Coronary Plaque Characteristics in Patients With Diabetes Mellitus Who Presented With Acute Coronary Syndromes. J Am Heart Assoc. 2018 Jul 13; 7(14). PMID: 30006490.
    Citations:    Fields:    
  7. Partida RA, Libby P, Crea F, Jang IK. Plaque erosion: a new in vivo diagnosis and a potential major shift in the management of patients with acute coronary syndromes. Eur Heart J. 2018 Jun 07; 39(22):2070-2076. PMID: 29329384.
    Citations: 3     Fields:    
  8. Fracassi F, Sugiyama T, Yamamoto E, Ghoshhajra B, Gin A, Albaghdadi M, Lee H, Melnitchouk S, Sundt TM, Jang IK. A combined fractional flow reserve and optical coherence tomography approach to guide coronary artery bypass grafting: A pilot study. J Thorac Cardiovasc Surg. 2018 Sep; 156(3):997-1000. PMID: 29960717.
    Citations:    Fields:    
  9. Sugiyama T, Xing L, Yamamoto E, Fracassi F, Lee H, Yu B, Jang IK. Thrombus resolution with tirofiban in the conservative management of patients presenting with plaque erosion. Coron Artery Dis. 2018 Jun; 29(4):301-308. PMID: 29494363.
    Citations:    Fields:    
  10. Bari S, Svaldi DO, Jang I, Shenk TE, Poole VN, Lee T, Dydak U, Rispoli JV, Nauman EA, Talavage TM. Dependence on subconcussive impacts of brain metabolism in collision sport athletes: an MR spectroscopic study. Brain Imaging Behav. 2018 May 25. PMID: 29802602.
    Citations:    Fields:    
  11. Sohn EJ, Kim JM, Kang SH, Kwon J, An HJ, Sung JS, Cho KA, Jang IS, Choi JS. Restoring Effects of Natural Anti-Oxidant Quercetin on Cellular Senescent Human Dermal Fibroblasts. Am J Chin Med. 2018; 46(4):853-873. PMID: 29737207.
    Citations: 1     Fields:    Translation:Cells
  12. Park S, Kim JM, Shin W, Han SW, Jeon M, Jang HJ, Jang IS, Kang J. BTNET : boosted tree based gene regulatory network inference algorithm using time-course measurement data. BMC Syst Biol. 2018 03 19; 12(Suppl 2):20. PMID: 29560827.
    Citations:    Fields:    
  13. Sugiyama T, Yamamoto E, Bryniarski K, Xing L, Lee H, Isobe M, Libby P, Jang IK. Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture: A 3-Vessel Optical Coherence Tomography Study. JAMA Cardiol. 2018 Mar 01; 3(3):207-214. PMID: 29417141.
    Citations: 3     Fields:    
  14. Bryniarski KL, Yamamoto E, Takumi H, Xing L, Zanchin T, Sugiyama T, Lee H, Jang IK. Differences in coronary plaque characteristics between patients with and those without peripheral arterial disease. Coron Artery Dis. 2017 Dec; 28(8):658-663. PMID: 28692481.
    Citations: 1     Fields:    Translation:HumansCells
  15. Xing L, Yamamoto E, Sugiyama T, Jia H, Ma L, Hu S, Wang C, Zhu Y, Li L, Xu M, Liu H, Bryniarski K, Hou J, Zhang S, Lee H, Yu B, Jang IK. EROSION Study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion): A 1-Year Follow-Up Report. Circ Cardiovasc Interv. 2017 Dec; 10(12). PMID: 29246916.
    Citations: 1     Fields:    Translation:Humans
  16. Yonetsu T, Jang IK. Advances in Intravascular Imaging: New Insights into the Vulnerable Plaque from Imaging Studies. Korean Circ J. 2018 Jan; 48(1):1-15. PMID: 29171202.
    Citations: 1     
  17. Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK. Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study. J Am Heart Assoc. 2017 Nov 01; 6(11). PMID: 29092845.
    Citations:    Fields:    Translation:Humans
  18. Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK. Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography. Coron Artery Dis. 2017 Nov; 28(7):557-563. PMID: 28704243.
    Citations:    Fields:    Translation:Humans
  19. Hwang IH, Oh SY, Jang HJ, Jo E, Joo JC, Lee KB, Yoo HS, Lee MY, Park SJ, Jang IS. Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression. PLoS One. 2017; 12(10):e0186489. PMID: 29045468.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  20. Jang IK. Plaque Progression: Slow Linear or Rapid Stepwise? Circ Cardiovasc Imaging. 2017 Sep; 10(9). PMID: 28893799.
    Citations:    Fields:    
  21. Yamamoto E, Siasos G, Zaromytidou M, Coskun AU, Xing L, Bryniarski K, Zanchin T, Sugiyama T, Lee H, Stone PH, Jang IK. Low Endothelial Shear Stress Predicts Evolution to High-Risk Coronary Plaque Phenotype in the Future: A Serial Optical Coherence Tomography and Computational Fluid Dynamics Study. Circ Cardiovasc Interv. 2017 Aug; 10(8). PMID: 28768758.
    Citations:    Fields:    Translation:Humans
  22. Bryniarski KL, Walters DL, Kim CJ, Soeda T, Higuma T, Yamamoto E, Xing L, Sugiyama T, Zanchin T, Bryniarski L, Dudek D, Lee H, Jang IK. SYNTAX Score and Pre- and Poststent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients With Stable Angina Pectoris. Am J Cardiol. 2017 Sep 15; 120(6):898-903. PMID: 28750824.
    Citations:    Fields:    Translation:Humans
  23. Choi BY, Joo JC, Lee YK, Jang IS, Park SJ, Park YJ. Anti-cancer effect of Scutellaria baicalensis in combination with cisplatin in human ovarian cancer cell. BMC Complement Altern Med. 2017 May 25; 17(1):277. PMID: 28545442.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  24. Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study. J Am Coll Cardiol. 2017 May 23; 69(20):2502-2513. PMID: 28521888.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  25. Dai J, Hou J, Xing L, Jia H, Hu S, Soeda T, Minami Y, Ong D, Vergallo R, Zhang S, Lee H, Yu B, Jang IK. Is age an important factor for vascular response to statin therapy? A serial optical coherence tomography and intravascular ultrasound study. Coron Artery Dis. 2017 May; 28(3):209-217. PMID: 28059849.
    Citations:    Fields:    Translation:Humans
  26. Kim JS, Son SH, Kim MY, Choi D, Jang IS, Paik SS, Chae JH, Uversky VN, Kim CG. Diagnostic and prognostic relevance of CP2c and YY1 expression in hepatocellular carcinoma. Oncotarget. 2017 Apr 11; 8(15):24389-24400. PMID: 28412749.
    Citations:    Fields:    Translation:Humans
  27. Bryniarski KL, Tahk SJ, Choi SY, Soeda T, Higuma T, Yamamoto E, Xing L, Dai J, Zanchin T, Lee H, Jang IK. Clinical, angiographic, IVUS, and OCT predictors for irregular protrusion after coronary stenting. EuroIntervention. 2017 Apr 07; 12(18):e2204-e2211. PMID: 27993755.
    Citations:    Fields:    Translation:Humans
  28. Jia H, Dai J, Hou J, Xing L, Ma L, Liu H, Xu M, Yao Y, Hu S, Yamamoto E, Lee H, Zhang S, Yu B, Jang IK. Effective anti-thrombotic therapy without stenting: intravascular optical coherence tomography-based management in plaque erosion (the EROSION study). Eur Heart J. 2017 Mar 14; 38(11):792-800. PMID: 27578806.
    Citations: 17     Fields:    Translation:Humans
  29. Hu S, Wang C, Zhe C, Zhu Y, Yonetsu T, Jia H, Hou J, Zhang S, Jang IK, Yu B. Plaque erosion delays vascular healing after drug eluting stent implantation in patients with acute coronary syndrome: An In Vivo Optical Coherence Tomography Study. Catheter Cardiovasc Interv. 2017 Mar; 89(S1):592-600. PMID: 28318137.
    Citations: 1     Fields:    Translation:Humans
  30. Hwang JH, Park SJ, Ko WG, Kang SM, Lee DB, Bang J, Park BJ, Wee CB, Kim DJ, Jang IS, Ko JH. Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway. Am J Cancer Res. 2017; 7(3):417-432. PMID: 28401001.
    Citations: 3     
  31. Dai J, Xing L, Hou J, Jia H, Hu S, Tian J, Lin L, Li L, Zhu Y, Zheng G, Zhang S, Yu B, Jang IK. Chronic kidney disease predicts coronary plaque vulnerability: an optical coherence tomography study. Coron Artery Dis. 2017 Mar; 28(2):135-144. PMID: 27922522.
    Citations:    Fields:    Translation:Humans
  32. Hu S, Zhu Y, Zhang Y, Dai J, Li L, Dauerman H, Soeda T, Wang Z, Lee H, Wang C, Zhe C, Wang Y, Zheng G, Zhang S, Jia H, Yu B, Jang IK. Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study. J Am Heart Assoc. 2017 Feb 24; 6(3). PMID: 28235809.
    Citations: 3     Fields:    Translation:Humans
  33. Thondapu V, Bourantas CV, Foin N, Jang IK, Serruys PW, Barlis P. Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling. Eur Heart J. 2017 01 07; 38(2):81-92. PMID: 28158723.
    Citations: 3     Fields:    Translation:HumansCells
  34. Minami Y, Hoyt T, Phipps JE, Milner TE, Xing L, Lee H, Yu B, Feldman MD, Jang IK. Lipid-lowering therapy stabilizes the complexity of non-culprit plaques in human coronary artery: a quantitative assessment using OCT bright spot algorithm. Int J Cardiovasc Imaging. 2017 Apr; 33(4):453-461. PMID: 27987040.
    Citations: 1     Fields:    Translation:Humans
  35. Gin AL, Vergallo R, Minami Y, Ong DS, Hou J, Jia H, Soeda T, Hu S, Zhang S, Lee H, Yu B, Jang IK. Changes in coronary plaque morphology in patients with acute coronary syndrome versus stable angina pectoris after initiation of statin therapy. Coron Artery Dis. 2016 Dec; 27(8):629-635. PMID: 27468140.
    Citations:    Fields:    Translation:Humans
  36. Xie Z, Hou J, Yu H, Jia H, Du H, Lee H, Yu B, Tian J, Jang IK. Patterns of coronary plaque progression: phasic versus gradual. A combined optical coherence tomography and intravascular ultrasound study. Coron Artery Dis. 2016 Dec; 27(8):658-666. PMID: 27580090.
    Citations:    Fields:    Translation:Humans
  37. Albaghdadi M, Jang IK. Flow and plaque phenotype. Coron Artery Dis. 2016 12; 27(8):621-622. PMID: 27798412.
    Citations:    Fields:    Translation:Humans
  38. Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Izumiyama K, Nishizaki F, Minami Y, Xing L, Yamamoto E, Lee H, Okumura K, Jang IK. Does Residual Thrombus After Aspiration Thrombectomy Affect the Outcome of Primary PCI in Patients With ST-Segment Elevation Myocardial Infarction?: An Optical Coherence Tomography Study. JACC Cardiovasc Interv. 2016 10 10; 9(19):2002-2011. PMID: 27712735.
    Citations: 4     Fields:    Translation:Humans
  39. Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK. Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study. Arterioscler Thromb Vasc Biol. 2016 11; 36(11):2229-2238. PMID: 27634834.
    Citations: 5     Fields:    Translation:Humans
  40. Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Nishizaki F, Xing L, Yamamoto E, Bryniarski K, Dai J, Lee H, Okumura K, Jang IK. Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment-Elevation Myocardial Infarction: A Combined Optical Coherence Tomography and Intravascular Ultrasound Study. Circ Cardiovasc Interv. 2016 09; 9(9). PMID: 27609831.
    Citations: 2     Fields:    Translation:Humans
  41. Vergallo R, Xing L, Minami Y, Soeda T, Ong DS, Gao L, Lee H, Guagliumi G, Biasucci LM, Crea F, Yu B, Uemura S, O'Donnell CJ, Jang IK. Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography. Coron Artery Dis. 2016 Sep; 27(6):460-6. PMID: 27218146.
    Citations:    Fields:    Translation:Humans
  42. Wang Z, Cho YS, Soeda T, Minami Y, Xing L, Jia H, Aguirre A, Vergallo R, Lee H, Fujimoto JG, Yu B, Jang IK. Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study. Coron Artery Dis. 2016 Aug; 27(5):350-6. PMID: 27105047; PMCID: PMC4912393.
    Citations:    Fields:    Translation:Humans
  43. Hwang IH, Kwon YK, Cho CK, Lee YW, Sung JS, Joo JC, Lee KB, Yoo HS, Jang IS. Modified Panax ginseng Extract Inhibits uPAR-Mediated a[Formula: see text]ß1-Integrin Signaling by Modulating Caveolin-1 to Induce Early Apoptosis in Lung Cancer Cells. Am J Chin Med. 2016; 44(5):1081-97. PMID: 27430913.
    Citations:    Fields:    Translation:HumansAnimalsCells
  44. Phipps JE, Hoyt T, Vela D, Wang T, Michalek JE, Buja LM, Jang IK, Milner TE, Feldman MD. Diagnosis of Thin-Capped Fibroatheromas in Intravascular Optical Coherence Tomography Images: Effects of Light Scattering. Circ Cardiovasc Interv. 2016 07; 9(7). PMID: 27406987.
    Citations: 5     Fields:    Translation:Humans
  45. Minami Y, Hou J, Xing L, Jia H, Hu S, Vergallo R, Soeda T, Lee H, Zhang S, Yu B, Jang IK. Serial Optical Coherence Tomography and Intravascular Ultrasound Analysis of Gender Difference in Changes of Plaque Phenotype in Response to Lipid-Lowering Therapy. Am J Cardiol. 2016 Jun 15; 117(12):1890-5. PMID: 27138187.
    Citations:    Fields:    Translation:Humans
  46. Thondapu V, Bourantas CV, Foin N, Jang IK, Serruys PW, Barlis P. Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling. Eur Heart J. 2016 Feb 22. PMID: 26903533.
    Citations:    
  47. Soeda T, Higuma T, Abe N, Yamada M, Yokoyama H, Shibutani S, Ong DS, Vergallo R, Minami Y, Lee H, Okumura K, Jang IK. Morphological predictors for no reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction caused by plaque rupture. Eur Heart J Cardiovasc Imaging. 2017 Jan; 18(1):103-110. PMID: 26800769.
    Citations: 1     Fields:    Translation:Humans
  48. Ong DS, Lee JS, Soeda T, Higuma T, Minami Y, Wang Z, Lee H, Yokoyama H, Yokota T, Okumura K, Jang IK. Coronary Calcification and Plaque Vulnerability: An Optical Coherence Tomographic Study. Circ Cardiovasc Imaging. 2016 Jan; 9(1). PMID: 26743463.
    Citations: 5     Fields:    Translation:Humans
  49. Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK. Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents. Coron Artery Dis. 2016 Jan; 27(1):19-28. PMID: 26554662.
    Citations:    Fields:    Translation:Humans
  50. Hou J, Xing L, Jia H, Vergallo R, Soeda T, Minami Y, Hu S, Yang S, Zhang S, Lee H, Yu B, Jang IK. Comparison of Intensive Versus Moderate Lipid-Lowering Therapy on Fibrous Cap and Atheroma Volume of Coronary Lipid-Rich Plaque Using Serial Optical Coherence Tomography and Intravascular Ultrasound Imaging. Am J Cardiol. 2016 Mar 01; 117(5):800-6. PMID: 26778524.
    Citations: 7     Fields:    Translation:Humans
  51. Gao L, Lee S, Kim CJ, Minami Y, Ong DS, Soeda T, Lowe H, Choi SY, Lerman A, Lee J, Lee H, Uemura S, Yu B, Jang IK. Incidence and Morphological Predictors of Intrastent Coronary Thrombus After Drug-Eluting Stent Implantation (from a Multicenter Registry). Am J Cardiol. 2016 Feb 01; 117(3):369-75. PMID: 26705880.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  52. Iannaccone M, Quadri G, Taha S, D'Ascenzo F, Montefusco A, Omede' P, Jang IK, Niccoli G, Souteyrand G, Yundai C, Toutouzas K, Benedetto S, Barbero U, Annone U, Lonni E, Imori Y, Biondi-Zoccai G, Templin C, Moretti C, Luscher TF, Gaita F. Prevalence and predictors of culprit plaque rupture at OCT in patients with coronary artery disease: a meta-analysis. Eur Heart J Cardiovasc Imaging. 2016 Oct; 17(10):1128-37. PMID: 26508517.
    Citations: 28     Fields:    Translation:Humans
  53. Vergallo R, Aguirre AD, Abtahian F, Minami Y, Soeda T, Chatzizisis YS, Croce K, Jang IK. Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome. Thromb Haemost. 2016 Jan; 115(2):237-9. PMID: 26423215.
    Citations: 2     Fields:    Translation:Humans