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profileIk-Kyung Jang, PH.D., M.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Cardiology, Gray/Bigelow 800
55 Fruit St
Boston MA 02114
Phone617/726-9226
Fax617/726-7419
vCardDownload vCard (login for email)

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Bryniarski KL, Yamamoto E, Takumi H, Xing L, Zanchin T, Sugiyama T, Lee H, Jang IK. Differences in coronary plaque characteristics between patients with and those without peripheral arterial disease. Coron Artery Dis. 2017 Dec; 28(8):658-663. PMID: 28692481.
    View in: PubMed
  2. Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK. Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography. Coron Artery Dis. 2017 Nov; 28(7):557-563. PMID: 28704243.
    View in: PubMed
  3. Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK. Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study. J Am Heart Assoc. 2017 Nov 01; 6(11). PMID: 29092845.
    View in: PubMed
  4. Hwang IH, Oh SY, Jang HJ, Jo E, Joo JC, Lee KB, Yoo HS, Lee MY, Park SJ, Jang IS. Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression. PLoS One. 2017; 12(10):e0186489. PMID: 29045468.
    View in: PubMed
  5. Jang IK. Plaque Progression: Slow Linear or Rapid Stepwise? Circ Cardiovasc Imaging. 2017 Sep; 10(9). PMID: 28893799.
    View in: PubMed
  6. Yamamoto E, Siasos G, Zaromytidou M, Coskun AU, Xing L, Bryniarski K, Zanchin T, Sugiyama T, Lee H, Stone PH, Jang IK. Low Endothelial Shear Stress Predicts Evolution to High-Risk Coronary Plaque Phenotype in the Future: A Serial Optical Coherence Tomography and Computational Fluid Dynamics Study. Circ Cardiovasc Interv. 2017 Aug; 10(8). PMID: 28768758.
    View in: PubMed
  7. Bryniarski KL, Walters DL, Kim CJ, Soeda T, Higuma T, Yamamoto E, Xing L, Sugiyama T, Zanchin T, Bryniarski L, Dudek D, Lee H, Jang IK. SYNTAX Score and Pre- and Poststent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients With Stable Angina Pectoris. Am J Cardiol. 2017 Sep 15; 120(6):898-903. PMID: 28750824.
    View in: PubMed
  8. Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study. J Am Coll Cardiol. 2017 May 23; 69(20):2502-2513. PMID: 28521888.
    View in: PubMed
  9. Dai J, Hou J, Xing L, Jia H, Hu S, Soeda T, Minami Y, Ong D, Vergallo R, Zhang S, Lee H, Yu B, Jang IK. Is age an important factor for vascular response to statin therapy? A serial optical coherence tomography and intravascular ultrasound study. Coron Artery Dis. 2017 May; 28(3):209-217. PMID: 28059849.
    View in: PubMed
  10. Bryniarski KL, Tahk SJ, Choi SY, Soeda T, Higuma T, Yamamoto E, Xing L, Dai J, Zanchin T, Lee H, Jang IK. Clinical, angiographic, IVUS, and OCT predictors for irregular protrusion after coronary stenting. EuroIntervention. 2017 Apr 07; 12(18):e2204-e2211. PMID: 27993755.
    View in: PubMed
  11. Jia H, Dai J, Hou J, Xing L, Ma L, Liu H, Xu M, Yao Y, Hu S, Yamamoto E, Lee H, Zhang S, Yu B, Jang IK. Effective anti-thrombotic therapy without stenting: intravascular optical coherence tomography-based management in plaque erosion (the EROSION study). Eur Heart J. 2017 Mar 14; 38(11):792-800. PMID: 27578806.
    View in: PubMed
  12. Hu S, Wang C, Zhe C, Zhu Y, Yonetsu T, Jia H, Hou J, Zhang S, Jang IK, Yu B. Plaque erosion delays vascular healing after drug eluting stent implantation in patients with acute coronary syndrome: An In Vivo Optical Coherence Tomography Study. Catheter Cardiovasc Interv. 2017 Mar; 89(S1):592-600. PMID: 28318137.
    View in: PubMed
  13. Hwang JH, Park SJ, Ko WG, Kang SM, Lee DB, Bang J, Park BJ, Wee CB, Kim DJ, Jang IS, Ko JH. Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway. Am J Cancer Res. 2017; 7(3):417-432. PMID: 28401001.
    View in: PubMed
  14. Dai J, Xing L, Hou J, Jia H, Hu S, Tian J, Lin L, Li L, Zhu Y, Zheng G, Zhang S, Yu B, Jang IK. Chronic kidney disease predicts coronary plaque vulnerability: an optical coherence tomography study. Coron Artery Dis. 2017 Mar; 28(2):135-144. PMID: 27922522.
    View in: PubMed
  15. Hu S, Zhu Y, Zhang Y, Dai J, Li L, Dauerman H, Soeda T, Wang Z, Lee H, Wang C, Zhe C, Wang Y, Zheng G, Zhang S, Jia H, Yu B, Jang IK. Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study. J Am Heart Assoc. 2017 Feb 24; 6(3). PMID: 28235809.
    View in: PubMed
  16. Thondapu V, Bourantas CV, Foin N, Jang IK, Serruys PW, Barlis P. Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling. Eur Heart J. 2017 01 07; 38(2):81-92. PMID: 28158723.
    View in: PubMed
  17. Minami Y, Hoyt T, Phipps JE, Milner TE, Xing L, Lee H, Yu B, Feldman MD, Jang IK. Lipid-lowering therapy stabilizes the complexity of non-culprit plaques in human coronary artery: a quantitative assessment using OCT bright spot algorithm. Int J Cardiovasc Imaging. 2017 Apr; 33(4):453-461. PMID: 27987040.
    View in: PubMed
  18. Gin AL, Vergallo R, Minami Y, Ong DS, Hou J, Jia H, Soeda T, Hu S, Zhang S, Lee H, Yu B, Jang IK. Changes in coronary plaque morphology in patients with acute coronary syndrome versus stable angina pectoris after initiation of statin therapy. Coron Artery Dis. 2016 Dec; 27(8):629-635. PMID: 27468140.
    View in: PubMed
  19. Xie Z, Hou J, Yu H, Jia H, Du H, Lee H, Yu B, Tian J, Jang IK. Patterns of coronary plaque progression: phasic versus gradual. A combined optical coherence tomography and intravascular ultrasound study. Coron Artery Dis. 2016 Dec; 27(8):658-666. PMID: 27580090.
    View in: PubMed
  20. Albaghdadi M, Jang IK. Flow and plaque phenotype. Coron Artery Dis. 2016 12; 27(8):621-622. PMID: 27798412.
    View in: PubMed
  21. Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Izumiyama K, Nishizaki F, Minami Y, Xing L, Yamamoto E, Lee H, Okumura K, Jang IK. Does Residual Thrombus After Aspiration Thrombectomy Affect the Outcome of Primary PCI in Patients With ST-Segment Elevation Myocardial Infarction?: An Optical Coherence Tomography Study. JACC Cardiovasc Interv. 2016 Oct 10; 9(19):2002-2011. PMID: 27712735.
    View in: PubMed
  22. Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK. Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study. Arterioscler Thromb Vasc Biol. 2016 Nov; 36(11):2229-2238. PMID: 27634834.
    View in: PubMed
  23. Higuma T, Soeda T, Yamada M, Yokota T, Yokoyama H, Nishizaki F, Xing L, Yamamoto E, Bryniarski K, Dai J, Lee H, Okumura K, Jang IK. Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment-Elevation Myocardial Infarction: A Combined Optical Coherence Tomography and Intravascular Ultrasound Study. Circ Cardiovasc Interv. 2016 Sep; 9(9). PMID: 27609831.
    View in: PubMed
  24. Vergallo R, Xing L, Minami Y, Soeda T, Ong DS, Gao L, Lee H, Guagliumi G, Biasucci LM, Crea F, Yu B, Uemura S, O'Donnell CJ, Jang IK. Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography. Coron Artery Dis. 2016 Sep; 27(6):460-6. PMID: 27218146.
    View in: PubMed
  25. Wang Z, Cho YS, Soeda T, Minami Y, Xing L, Jia H, Aguirre A, Vergallo R, Lee H, Fujimoto JG, Yu B, Jang IK. Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study. Coron Artery Dis. 2016 Aug; 27(5):350-6. PMID: 27105047; PMCID: PMC4912393 [Available on 08/01/17].
  26. Hwang IH, Kwon YK, Cho CK, Lee YW, Sung JS, Joo JC, Lee KB, Yoo HS, Jang IS. Modified Panax ginseng Extract Inhibits uPAR-Mediated a[Formula: see text]ß1-Integrin Signaling by Modulating Caveolin-1 to Induce Early Apoptosis in Lung Cancer Cells. Am J Chin Med. 2016; 44(5):1081-97. PMID: 27430913.
    View in: PubMed
  27. Phipps JE, Hoyt T, Vela D, Wang T, Michalek JE, Buja LM, Jang IK, Milner TE, Feldman MD. Diagnosis of Thin-Capped Fibroatheromas in Intravascular Optical Coherence Tomography Images: Effects of Light Scattering. Circ Cardiovasc Interv. 2016 Jul; 9(7). PMID: 27406987; PMCID: PMC4946571 [Available on 07/01/17].
  28. Minami Y, Hou J, Xing L, Jia H, Hu S, Vergallo R, Soeda T, Lee H, Zhang S, Yu B, Jang IK. Serial Optical Coherence Tomography and Intravascular Ultrasound Analysis of Gender Difference in Changes of Plaque Phenotype in Response to Lipid-Lowering Therapy. Am J Cardiol. 2016 Jun 15; 117(12):1890-5. PMID: 27138187.
    View in: PubMed
  29. Thondapu V, Bourantas CV, Foin N, Jang IK, Serruys PW, Barlis P. Biomechanical stress in coronary atherosclerosis: emerging insights from computational modelling. Eur Heart J. 2016 Feb 22. PMID: 26903533.
    View in: PubMed
  30. Soeda T, Higuma T, Abe N, Yamada M, Yokoyama H, Shibutani S, Ong DS, Vergallo R, Minami Y, Lee H, Okumura K, Jang IK. Morphological predictors for no reflow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction caused by plaque rupture. Eur Heart J Cardiovasc Imaging. 2017 Jan; 18(1):103-110. PMID: 26800769.
    View in: PubMed
  31. Ong DS, Lee JS, Soeda T, Higuma T, Minami Y, Wang Z, Lee H, Yokoyama H, Yokota T, Okumura K, Jang IK. Coronary Calcification and Plaque Vulnerability: An Optical Coherence Tomographic Study. Circ Cardiovasc Imaging. 2016 Jan; 9(1). PMID: 26743463.
    View in: PubMed
  32. Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK. Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents. Coron Artery Dis. 2016 Jan; 27(1):19-28. PMID: 26554662.
    View in: PubMed
  33. Hou J, Xing L, Jia H, Vergallo R, Soeda T, Minami Y, Hu S, Yang S, Zhang S, Lee H, Yu B, Jang IK. Comparison of Intensive Versus Moderate Lipid-Lowering Therapy on Fibrous Cap and Atheroma Volume of Coronary Lipid-Rich Plaque Using Serial Optical Coherence Tomography and Intravascular Ultrasound Imaging. Am J Cardiol. 2016 Mar 01; 117(5):800-6. PMID: 26778524.
    View in: PubMed
  34. Gao L, Lee S, Kim CJ, Minami Y, Ong DS, Soeda T, Lowe H, Choi SY, Lerman A, Lee J, Lee H, Uemura S, Yu B, Jang IK. Incidence and Morphological Predictors of Intrastent Coronary Thrombus After Drug-Eluting Stent Implantation (from a Multicenter Registry). Am J Cardiol. 2016 Feb 01; 117(3):369-75. PMID: 26705880.
    View in: PubMed
  35. Iannaccone M, Quadri G, Taha S, D'Ascenzo F, Montefusco A, Omede' P, Jang IK, Niccoli G, Souteyrand G, Yundai C, Toutouzas K, Benedetto S, Barbero U, Annone U, Lonni E, Imori Y, Biondi-Zoccai G, Templin C, Moretti C, Luscher TF, Gaita F. Prevalence and predictors of culprit plaque rupture at OCT in patients with coronary artery disease: a meta-analysis. Eur Heart J Cardiovasc Imaging. 2016 Oct; 17(10):1128-37. PMID: 26508517.
    View in: PubMed
  36. Vergallo R, Aguirre AD, Abtahian F, Minami Y, Soeda T, Chatzizisis YS, Croce K, Jang IK. Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome. Thromb Haemost. 2016 Jan; 115(2):237-9. PMID: 26423215.
    View in: PubMed
  37. Jones CR, Khandhar SJ, Ramratnam M, Mulukutla SR, Marroquin OC, Althouse AD, Rao A, Kato K, Jang IK, Toma C. Identification of Intrastent Pathology Associated With Late Stent Thrombosis Using Optical Coherence Tomography. J Interv Cardiol. 2015 Oct; 28(5):439-48. PMID: 26381509.
    View in: PubMed
  38. Ain DL, Jang IK. Natural history of coronary atherosclerosis: did contemporary medical therapy change the course? Coron Artery Dis. 2015 Sep; 26(6):463-5. PMID: 26217890.
    View in: PubMed
  39. Hayat U, Thondapu V, Ul Haq MA, Foin N, Jang IK, Barlis P. Optical coherence tomography to evaluate coronary stent implantation and complications. Coron Artery Dis. 2015 Aug; 26 Suppl 1:e55-68. PMID: 26247272.
    View in: PubMed
  40. Papafaklis MI, Bourantas CV, Yonetsu T, Vergallo R, Kotsia A, Nakatani S, Lakkas LS, Athanasiou LS, Naka KK, Fotiadis DI, Feldman CL, Stone PH, Serruys PW, Jang IK, Michalis LK. Anatomically correct three-dimensional coronary artery reconstruction using frequency domain optical coherence tomographic and angiographic data: head-to-head comparison with intravascular ultrasound for endothelial shear stress assessment in humans. EuroIntervention. 2015 Aug; 11(4):407-15. PMID: 24974809.
    View in: PubMed
  41. Minami Y, Phipps JE, Hoyt T, Milner TE, Ong DS, Soeda T, Vergallo R, Feldman MD, Jang IK. Clinical utility of quantitative bright spots analysis in patients with acute coronary syndrome: an optical coherence tomography study. Int J Cardiovasc Imaging. 2015 Dec; 31(8):1479-87. PMID: 26202158.
    View in: PubMed
  42. Soeda T, Uemura S, Park SJ, Jang Y, Lee S, Cho JM, Kim SJ, Vergallo R, Minami Y, Ong DS, Gao L, Lee H, Zhang S, Yu B, Saito Y, Jang IK. Incidence and Clinical Significance of Poststent Optical Coherence Tomography Findings: One-Year Follow-Up Study From a Multicenter Registry. Circulation. 2015 Sep 15; 132(11):1020-9. PMID: 26162917.
    View in: PubMed
  43. Higuma T, Soeda T, Abe N, Yamada M, Yokoyama H, Shibutani S, Vergallo R, Minami Y, Ong DS, Lee H, Okumura K, Jang IK. A Combined Optical Coherence Tomography and Intravascular Ultrasound Study on Plaque Rupture, Plaque Erosion, and Calcified Nodule in Patients With ST-Segment Elevation Myocardial Infarction: Incidence, Morphologic Characteristics, and Outcomes After Percutaneous Coronary Intervention. JACC Cardiovasc Interv. 2015 Aug 17; 8(9):1166-1176. PMID: 26117464.
    View in: PubMed
  44. Gao L, Park SJ, Jang Y, Lee S, Kim CJ, Minami Y, Ong D, Soeda T, Vergallo R, Lee H, Yu B, Uemura S, Jang IK. Comparison of Neoatherosclerosis and Neovascularization Between Patients With and Without Diabetes: An Optical Coherence Tomography Study. JACC Cardiovasc Interv. 2015 Jul; 8(8):1044-1052. PMID: 26117465.
    View in: PubMed
  45. Ong DS, Jang IK. Fundamentals of Optical Coherence Tomography: Image Acquisition and Interpretation. Interv Cardiol Clin. 2015 Jul; 4(3):225-237. PMID: 28581942.
    View in: PubMed
  46. Minami Y, Jang IK. Can optical coherence tomography objectively assess neointimal pattern after stenting? Coron Artery Dis. 2015 May; 26(3):192-3. PMID: 25837649.
    View in: PubMed
  47. Minami Y, Ong DS, Uemura S, Wang Z, Aguirre AD, Mukhopadhyay S, Soeda T, Vergallo R, Jia H, Tian J, Hu S, Kim SJ, Park CB, Dauerman HL, Lee S, Jang IK. Impacts of lesion angle on incidence and distribution of acute vessel wall injuries and strut malapposition after drug-eluting stent implantation assessed by optical coherence tomography. Eur Heart J Cardiovasc Imaging. 2015 Dec; 16(12):1390-8. PMID: 25925215.
    View in: PubMed
  48. Abtahian F, Waldo S, Jang IK. Comparison of heparin and bivalirudin in patients undergoing percutaneous coronary intervention without use of glycoprotein IIb/IIIa inhibitors. Catheter Cardiovasc Interv. 2015 Sep; 86(3):390-6. PMID: 25753749.
    View in: PubMed
  49. Ong DS, Jang IK. Causes, assessment, and treatment of stent thrombosis--intravascular imaging insights. Nat Rev Cardiol. 2015 Jun; 12(6):325-36. PMID: 25781415.
    View in: PubMed
  50. Jia H, Hu S, Uemura S, Park SJ, Jang Y, Prasad A, Lee S, Soeda T, Abtahian F, Vergallo R, Tian J, Lee H, Stone PH, Yu B, Jang IK. Insights into the spatial distribution of lipid-rich plaques in relation to coronary artery bifurcations: an in-vivo optical coherence tomography study. Coron Artery Dis. 2015 Mar; 26(2):133-41. PMID: 25356817.
    View in: PubMed
  51. Gao L, Park SJ, Jang Y, Lee S, Tian J, Minami Y, Jia H, Ong D, Soeda T, Vergallo R, Lee H, Yu B, Uemura S, Jang IK. Optical coherence tomographic evaluation of the effect of cigarette smoking on vascular healing after sirolimus-eluting stent implantation. Am J Cardiol. 2015 Mar 15; 115(6):751-7. PMID: 25620038.
    View in: PubMed
  52. Hwang JH, Sung JS, Kim JM, Chung YH, Park JS, Lee SH, Jang IS. Caveolin-1-dependent and -independent uPAR signaling pathways contribute to ganglioside GT1b induced early apoptosis in A549 lung cancer cells. Am J Cancer Res. 2014; 4(6):801-10. PMID: 25520869; PMCID: PMC4266713.
  53. Rassi AN, O'Dea JA, Jia H, Seto AH, Jang IK. Nonangiographic assessment of coronary artery disease: a practical approach to optical coherence tomography and fractional flow reserve. Coron Artery Dis. 2014 Nov; 25(7):608-18. PMID: 25203101.
    View in: PubMed
  54. Walters DL, Christopher Raffel O, Jang IK. Are the findings of optical coherence tomography sufficient for the evaluation of the safety and efficacy of the next generation of drug eluting stents? Int J Cardiol. 2015 Jan 20; 179:127-8. PMID: 25464431.
    View in: PubMed
  55. Vergallo R, Papafaklis MI, Yonetsu T, Bourantas CV, Andreou I, Wang Z, Fujimoto JG, McNulty I, Lee H, Biasucci LM, Crea F, Feldman CL, Michalis LK, Stone PH, Jang IK. Endothelial shear stress and coronary plaque characteristics in humans: combined frequency-domain optical coherence tomography and computational fluid dynamics study. Circ Cardiovasc Imaging. 2014 Nov; 7(6):905-11. PMID: 25190591.
    View in: PubMed
  56. Vergallo R, Joye R, Barlis P, Jia H, Tian J, Soeda T, Minami Y, Hu S, Dauerman HL, Toma C, Chan J, Lee H, Biasucci LM, Crea F, Jang IK. Bivalirudin versus unfractionated heparin for residual thrombus burden: a frequency-domain optical coherence tomography study. Catheter Cardiovasc Interv. 2015 Mar; 85(4):575-82. PMID: 25115992.
    View in: PubMed
  57. Tian J, Dauerman H, Toma C, Samady H, Itoh T, Kuramitsu S, Domei T, Jia H, Vergallo R, Soeda T, Hu S, Minami Y, Lee H, Yu B, Jang IK. Prevalence and characteristics of TCFA and degree of coronary artery stenosis: an OCT, IVUS, and angiographic study. J Am Coll Cardiol. 2014 Aug 19; 64(7):672-80. PMID: 25125298.
    View in: PubMed
  58. Tian J, Vergallo R, Jia H, Soeda T, Lee H, Yu B, Jang IK. Morphologic characteristics of eroded coronary plaques: a combined angiographic, optical coherence tomography, and intravascular ultrasound study. Int J Cardiol. 2014 Oct 20; 176(3):e137-9. PMID: 25127333.
    View in: PubMed
  59. Samy B, Soeda T, Januzzi JL, Gaggin HK, Jang IK. Different vascular responses within the same stent detected by optical coherence tomography. Coron Artery Dis. 2014 Aug; 25(5):450-1. PMID: 24842613.
    View in: PubMed
  60. Wang Z, Jia H, Tian J, Soeda T, Vergallo R, Minami Y, Lee H, Aguirre A, Fujimoto JG, Jang IK. Computer-aided image analysis algorithm to enhance in vivo diagnosis of plaque erosion by intravascular optical coherence tomography. Circ Cardiovasc Imaging. 2014 Sep; 7(5):805-10. PMID: 25034595.
    View in: PubMed
  61. Park EC, Kim SI, Hong Y, Hwang JW, Cho GS, Cha HN, Han JK, Yun CH, Park SY, Jang IS, Lee ZW, Choi JS, Kim S, Kim GH. Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in mice. Gastroenterology. 2014 Oct; 147(4):860-9. PMID: 24983671.
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  62. Abtahian F, Yonetsu T, Kato K, Jia H, Vergallo R, Tian J, Hu S, McNulty I, Lee H, Yu B, Jang IK. Comparison by optical coherence tomography of the frequency of lipid coronary plaques in current smokers, former smokers, and nonsmokers. Am J Cardiol. 2014 Sep 01; 114(5):674-80. PMID: 25048344.
    View in: PubMed
  63. Garcia-Garcia HM, Jang IK, Serruys PW, Kovacic JC, Narula J, Fayad ZA. Imaging plaques to predict and better manage patients with acute coronary events. Circ Res. 2014 Jun 06; 114(12):1904-17. PMID: 24902974; PMCID: PMC4128696.
  64. Hu S, Jia H, Vergallo R, Abtahian F, Tian J, Soeda T, Rosenfield K, Jang IK. Plaque erosion: in vivo diagnosis and treatment guided by optical coherence tomography. JACC Cardiovasc Interv. 2014 Jun; 7(6):e63-4. PMID: 24947729.
    View in: PubMed
  65. Vergallo R, Jia H, Soeda T, Tian J, Jang IK. Interpretation of optical coherence tomography images. Lancet. 2014 May 31; 383(9932):1887. PMID: 24881991.
    View in: PubMed
  66. Tian J, Ren X, Uemura S, Dauerman H, Prasad A, Toma C, Jia H, Abtahian F, Vergallo R, Hu S, McNulty I, Lee H, Lee S, Yu B, Jang IK. Spatial heterogeneity of neoatherosclerosis and its relationship with neovascularization and adjacent plaque characteristics: optical coherence tomography study. Am Heart J. 2014 Jun; 167(6):884-92.e2. PMID: 24890539.
    View in: PubMed
  67. Tian J, Ren X, Vergallo R, Xing L, Yu H, Jia H, Soeda T, McNulty I, Hu S, Lee H, Yu B, Jang IK. Distinct morphological features of ruptured culprit plaque for acute coronary events compared to those with silent rupture and thin-cap fibroatheroma: a combined optical coherence tomography and intravascular ultrasound study. J Am Coll Cardiol. 2014 Jun 03; 63(21):2209-16. PMID: 24632266.
    View in: PubMed
  68. Di Vito L, Yoon JH, Kato K, Yonetsu T, Vergallo R, Costa M, Bezerra HG, Arbustini E, Narula J, Crea F, Prati F, Jang IK. Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses. Coron Artery Dis. 2014 Mar; 25(2):172-85. PMID: 24356250.
    View in: PubMed
  69. Ryu HW, Choi SH, Namkoong S, Jang IS, Seo DH, Choi I, Kim HS, Park J. Simulated microgravity contributes to autophagy induction by regulating AMP-activated protein kinase. DNA Cell Biol. 2014 Mar; 33(3):128-35. PMID: 24387300.
    View in: PubMed
  70. Gu X, Hou J, Yang S, Yu H, Tian J, Liu F, Li N, Yu B, Jang IK. Is lipoprotein-associated phospholipase A2 activity correlated with fibrous-cap thickness and plaque volume in patients with acute coronary syndrome? Coron Artery Dis. 2014 Jan; 25(1):10-5. PMID: 24089018.
    View in: PubMed
  71. Hu S, Yonetsu T, Jia H, Karanasos A, Aguirre AD, Tian J, Abtahian F, Vergallo R, Soeda T, Lee H, McNulty I, Kato K, Yu B, Mizuno K, Toutouzas K, Stefanadis C, Jang IK. Residual thrombus pattern in patients with ST-segment elevation myocardial infarction caused by plaque erosion versus plaque rupture after successful fibrinolysis: an optical coherence tomography study. J Am Coll Cardiol. 2014 Apr 08; 63(13):1336-1338. PMID: 24361315.
    View in: PubMed
  72. Zeglin-Sawczuk M, Jang IK, Kato K, Yonetsu T, Kim S, Choi SY, Kratlian C, Lee H, Dauerman HL. Lipid rich plaque, female gender and proximal coronary stent edge dissections. J Thromb Thrombolysis. 2013 Nov; 36(4):507-13. PMID: 23378150.
    View in: PubMed
  73. Vergallo R, Ren X, Yonetsu T, Kato K, Uemura S, Yu B, Jia H, Abtahian F, Aguirre AD, Tian J, Hu S, Soeda T, Lee H, McNulty I, Park SJ, Jang Y, Prasad A, Lee S, Zhang S, Porto I, Biasucci LM, Crea F, Jang IK. Pancoronary plaque vulnerability in patients with acute coronary syndrome and ruptured culprit plaque: a 3-vessel optical coherence tomography study. Am Heart J. 2014 Jan; 167(1):59-67. PMID: 24332143.
    View in: PubMed
  74. Yonetsu T, Kato K, Uemura S, Kim BK, Jang Y, Kang SJ, Park SJ, Lee S, Kim SJ, Jia H, Vergallo R, Abtahian F, Tian J, Hu S, Yeh RW, Sakhuja R, McNulty I, Lee H, Zhang S, Yu B, Kakuta T, Jang IK. Features of coronary plaque in patients with metabolic syndrome and diabetes mellitus assessed by 3-vessel optical coherence tomography. Circ Cardiovasc Imaging. 2013 Sep; 6(5):665-73. PMID: 23922003.
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  93. Namkoong S, Lee EJ, Jang IS, Park J. Elevated level of human RPA interacting protein a (hRIPa) in cervical tumor cells is involved in cell proliferation through regulating RPA transport. FEBS Lett. 2012 Oct 19; 586(20):3753-60. PMID: 23010595.
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  101. Hou J, Lv H, Jia H, Zhang S, Xing L, Liu H, Kong J, Zhang S, Yu B, Jang IK. OCT assessment of allograft vasculopathy in heart transplant recipients. JACC Cardiovasc Imaging. 2012 Jun; 5(6):662-3. PMID: 22698538.
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  104. Yoon JH, Di Vito L, Moses JW, Fearon WF, Yeung AC, Zhang S, Bezerra HG, Costa MA, Jang IK. Feasibility and safety of the second-generation, frequency domain optical coherence tomography (FD-OCT): a multicenter study. J Invasive Cardiol. 2012 May; 24(5):206-9. PMID: 22562913.
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  112. Harikrishnan R, Kim JS, Jang IS, Kim MC, Balasundaram C, Heo MS. Molecular characterization and tissue distribution of ferritin M in kelp grouper, Epinephelus bruneus. J Biosci Bioeng. 2011 Dec; 112(6):541-4. PMID: 21885330.
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  114. Yoon JH, Her S, Kim M, Jang IS, Park J. The expression of damage-regulated autophagy modulator 2 (DRAM2) contributes to autophagy induction. Mol Biol Rep. 2012 Feb; 39(2):1087-93. PMID: 21584698.
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  116. Yoon JH, Jang IK. Heparin-induced thrombocytopenia in cardiovascular patients: pathophysiology, diagnosis, and treatment. Cardiol Rev. 2011 May-Jun; 19(3):143-53. PMID: 21464642.
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  129. Yoon JH, Yeh RW, Nam KH, Hoffman WD, Agnihotri AK, Jang IK. Safety and efficacy of the argatroban therapy during the early post-cardiac surgery period. J Thromb Thrombolysis. 2010 Oct; 30(3):276-80. PMID: 20449633.
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  132. Rhim JH, Jang IS, Kwon ST, Song KY, Yeo EJ, Park SC. Activation of wound healing in aged rats by altering the cellular mitogenic potential. J Gerontol A Biol Sci Med Sci. 2010 Jul; 65(7):704-11. PMID: 20457578.
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  138. Harikrishnan R, Kim MC, Kim JS, Han YJ, Jang IS, Balasundaram C, Heo MS. Immune response and expression analysis of cathepsin K in goldfish during Aeromonas hydrophila infection. Fish Shellfish Immunol. 2010 Apr; 28(4):511-6. PMID: 20025977.
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  139. Park SM, Chae M, Kim BK, Seo T, Jang IS, Choi JS, Kim IC, Lee JH, Park J. SUMOylated IRF-1 shows oncogenic potential by mimicking IRF-2. Biochem Biophys Res Commun. 2010 Jan 01; 391(1):926-30. PMID: 19962964.
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  141. Cho JM, Sohn IS, Jang IK. Late sequela of Kawasaki's disease: Optical coherence tomographic finding. J Invasive Cardiol. 2009 Dec; 21(12):668. PMID: 19966372.
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  142. Prati F, Regar E, Mintz GS, Arbustini E, Di Mario C, Jang IK, Akasaka T, Costa M, Guagliumi G, Grube E, Ozaki Y, Pinto F, Serruys PW. Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis. Eur Heart J. 2010 Feb; 31(4):401-15. PMID: 19892716.
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  143. Park SM, Kim K, Lee EJ, Kim BK, Lee TJ, Seo T, Jang IS, Lee SH, Kim S, Lee JH, Park J. Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death. Biochem Biophys Res Commun. 2009 Dec 25; 390(4):1340-4. PMID: 19895784.
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  146. Rhim JH, Jang IS, Choi JS, Kwon HJ, Yeo EJ, Park SC. Time-dependent differential gene expression in lysophosphatidic acid-treated young and senescent human diploid fibroblasts. Mech Ageing Dev. 2009 Sep; 130(9):648-51. PMID: 19563823.
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  150. Low AF, Kawase Y, Chan YH, Tearney GJ, Bouma BE, Jang IK. In vivo characterisation of coronary plaques with conventional grey-scale intravascular ultrasound: correlation with optical coherence tomography. EuroIntervention. 2009 Mar; 4(5):626-32. PMID: 19378684; PMCID: PMC3425358.
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  154. Hursting MJ, Jang IK. Dosing patterns and outcomes in African American, Asian, and Hispanic patients with heparin-induced thrombocytopenia treated with argatroban. J Thromb Thrombolysis. 2009 Jul; 28(1):10-5. PMID: 19016311.
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  155. Chia S, Nagurney JT, Brown DF, Raffel OC, Bamberg F, Senatore F, Wackers FJ, Jang IK. Association of leukocyte and neutrophil counts with infarct size, left ventricular function and outcomes after percutaneous coronary intervention for ST-elevation myocardial infarction. Am J Cardiol. 2009 Feb 01; 103(3):333-7. PMID: 19166685.
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  156. Rogg JG, De Neve JW, Huang C, Brown D, Jang IK, Chang Y, Marill K, Parry B, Hoffmann U, Nagurney JT. The triple work-up for emergency department patients with acute chest pain: how often does it occur? J Emerg Med. 2011 Feb; 40(2):128-34. PMID: 18790585.
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  158. Rhim JH, Jang IS, Song KY, Ha MK, Cho SC, Yeo EJ, Park SC. Lysophosphatidic acid and adenylyl cyclase inhibitor increase proliferation of senescent human diploid fibroblasts by inhibiting adenosine monophosphate-activated protein kinase. Rejuvenation Res. 2008 Aug; 11(4):781-92. PMID: 18729810.
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  241. Jang IS, Yeo EJ, Park JA, Ahn JS, Park JS, Cho KA, Juhnn YS, Park SC. Altered cAMP signaling induced by lysophosphatidic acid in senescent human diploid fibroblasts. Biochem Biophys Res Commun. 2003 Mar 21; 302(4):778-84. PMID: 12646237.
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  242. Bouma BE, Tearney GJ, Yabushita H, Shishkov M, Kauffman CR, DeJoseph Gauthier D, MacNeill BD, Houser SL, Aretz HT, Halpern EF, Jang IK. Evaluation of intracoronary stenting by intravascular optical coherence tomography. Heart. 2003 Mar; 89(3):317-20. PMID: 12591841; PMCID: PMC1767586.
  243. Januzzi JL, Sabatine MS, Wan Y, Servoss SJ, DiBattiste PM, Jang Ik, Theroux P. Interactions between age, outcome of acute coronary syndromes, and tirofiban therapy. Am J Cardiol. 2003 Feb 15; 91(4):457-61. PMID: 12586266.
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  244. Wykrzykowska JJ, Kathiresan S, Jang IK. Clinician update: direct thrombin inhibitors in acute coronary syndromes. J Thromb Thrombolysis. 2003 Feb; 15(1):47-57. PMID: 14574076.
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  245. Tearney GJ, Yabushita H, Houser SL, Aretz HT, Jang IK, Schlendorf KH, Kauffman CR, Shishkov M, Halpern EF, Bouma BE. Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography. Circulation. 2003 Jan 07; 107(1):113-9. PMID: 12515752.
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  246. Lowe HC, Neill BD, Van de Werf F, Jang IK. Pharmacologic reperfusion therapy for acute myocardial infarction. J Thromb Thrombolysis. 2002 Dec; 14(3):179-96. PMID: 12913398.
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  247. Mac Neill BD, Hayase M, Jang IK. The comparison between optical coherence tomography and intravascular ultrasound. Minerva Cardioangiol. 2002 Oct; 50(5):497-506. PMID: 12384632.
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  248. Yabushita H, Bouma BE, Houser SL, Aretz HT, Jang IK, Schlendorf KH, Kauffman CR, Shishkov M, Kang DH, Halpern EF, Tearney GJ. Characterization of human atherosclerosis by optical coherence tomography. Circulation. 2002 Sep 24; 106(13):1640-5. PMID: 12270856.
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  249. Jang IK. Direct thrombin inhibitors in acute coronary syndromes. Lancet. 2002 Aug 10; 360(9331):491-2; author reply 492. PMID: 12241752.
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  250. Januzzi JL, Snapinn SM, DiBattiste PM, Jang IK, Theroux P. Benefits and safety of tirofiban among acute coronary syndrome patients with mild to moderate renal insufficiency: results from the Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) trial. Circulation. 2002 May 21; 105(20):2361-6. PMID: 12021221.
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  251. Sheynberg BV, Jang IK, Han RO, Sabatine MS, Brown DF, Dinsmore R. Comparison of two different methods of quantitative coronary angiography in patients with acute coronary syndromes. Catheter Cardiovasc Interv. 2002 Apr; 55(4):442-9. PMID: 11948889.
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  252. Walters DL, Harding SA, Walsh CR, Wong P, Pomerantsev E, Jang IK. Acute coronary syndrome is a common clinical presentation of in-stent restenosis. Am J Cardiol. 2002 Mar 01; 89(5):491-4. PMID: 11867029.
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  253. Jang IK, Bouma BE, Kang DH, Park SJ, Park SW, Seung KB, Choi KB, Shishkov M, Schlendorf K, Pomerantsev E, Houser SL, Aretz HT, Tearney GJ. Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound. J Am Coll Cardiol. 2002 Feb 20; 39(4):604-9. PMID: 11849858.
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  254. Kathiresan S, Shiomura J, Jang IK. Argatroban. J Thromb Thrombolysis. 2002 Feb; 13(1):41-7. PMID: 11994559.
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  255. Jang IK, Tearney G, Bouma B. Visualization of tissue prolapse between coronary stent struts by optical coherence tomography: comparison with intravascular ultrasound. Circulation. 2001 Nov 27; 104(22):2754. PMID: 11723031.
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  256. Sabatine MS, Januzzi JL, Snapinn S, Théroux P, Jang IK. A risk score system for predicting adverse outcomes and magnitude of benefit with glycoprotein IIb/IIIa inhibitor therapy in patients with unstable angina pectoris. Am J Cardiol. 2001 Sep 01; 88(5):488-92. PMID: 11524055.
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  257. Wong P, Harding S, Walters D, Hull ML, Jang IK. Vascular complications after hemostatic puncture closure device (Angio-Seal) are not higher in overweight patients. J Invasive Cardiol. 2001 Sep; 13(9):623-5. PMID: 11533497.
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  258. Januzzi JL, Chae CU, Sabatine MS, Jang IK. Elevation in serum troponin I predicts the benefit of tirofiban. J Thromb Thrombolysis. 2001 May; 11(3):211-5. PMID: 11577259.
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  259. Lewis BE, Wallis DE, Berkowitz SD, Matthai WH, Fareed J, Walenga JM, Bartholomew J, Sham R, Lerner RG, Zeigler ZR, Rustagi PK, Jang IK, Rifkin SD, Moran J, Hursting MJ, Kelton JG. Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation. 2001 Apr 10; 103(14):1838-43. PMID: 11294800.
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  260. Jang IK. Fundamental concepts in the pathobiology of heparin-induced thrombocytopenia. J Thromb Thrombolysis. 2000 Nov; 10 Suppl 1:7-11. PMID: 11155189.
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  261. Abernethy WB, Choo JK, Oesterle SN, Jang IK. Balloon deflection technique: A method to facilitate entry of a balloon catheter into a deployed stent. Catheter Cardiovasc Interv. 2000 Nov; 51(3):312-3. PMID: 11066114.
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  262. Januzzi JL, Hahn SS, Chae CU, Giugliano R, Lewandrowski K, Theroux P, Jang IK. Effects of tirofiban plus heparin versus heparin alone on troponin I levels in patients with acute coronary syndromes. Am J Cardiol. 2000 Oct 01; 86(7):713-7. PMID: 11018188.
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  263. Kalra A, Jang IK. Prevalence of early left ventricular thrombus after primary coronary intervention for acute myocardial infarction. J Thromb Thrombolysis. 2000 Oct; 10(2):133-6. PMID: 11005935.
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  264. Sabatine MS, Tu TM, Jang IK. Combination of a direct thrombin inhibitor and a platelet glycoprotein IIb/IIIa blocking peptide facilitates and maintains reperfusion of platelet-rich thrombus with alteplase. J Thromb Thrombolysis. 2000 Oct; 10(2):189-96. PMID: 11005941.
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  265. Sabatine MS, Jang IK. The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease. Am J Med. 2000 Aug 15; 109(3):224-37. PMID: 10974186.
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  266. Tearney GJ, Jang IK, Kang DH, Aretz HT, Houser SL, Brady TJ, Schlendorf K, Shishkov M, Bouma BE. Porcine coronary imaging in vivo by optical coherence tomography. Acta Cardiol. 2000 Aug; 55(4):233-7. PMID: 11041121.
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  267. Gimelli G, Kalra A, Sabatine MS, Jang IK. Primary versus rescue percutaneous coronary intervention in patients with acute myocardial infarction. Acta Cardiol. 2000 Jun; 55(3):187-92. PMID: 10902044.
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  268. Chiang YJ, Kole HK, Brown K, Naramura M, Fukuhara S, Hu RJ, Jang IK, Gutkind JS, Shevach E, Gu H. Cbl-b regulates the CD28 dependence of T-cell activation. Nature. 2000 Jan 13; 403(6766):216-20. PMID: 10646609.
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  269. Kathiresan S, Jordan MK, Gimelli G, Lopez-Cuellar J, Madhi N, Jang IK. Frequency of silent myocardial ischemia following coronary stenting. Am J Cardiol. 1999 Oct 15; 84(8):930-2, A7. PMID: 10532514.
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  270. Januzzi JL, Jang IK. Heparin induced thrombocytopenia: diagnosis and contemporary antithrombin management. J Thromb Thrombolysis. 1999 Jun; 7(3):259-64. PMID: 10375387.
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  271. Jang IK, Brown DF, Giugliano RP, Anderson HV, Losordo D, Nicolau JC, Dutra OP, Bazzino O, Viamonte VM, Norbady R, Liprandi AS, Massey TJ, Dinsmore R, Schwarz RP. A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol. 1999 Jun; 33(7):1879-85. PMID: 10362188.
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  272. Sabatine MS, Jang IK. Antithrombotic therapy in acute coronary syndromes. Acta Cardiol. 1999 Feb; 54(1):3-29. PMID: 10214473.
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  273. Boeve TJ, Reed GL, Titus J, Janssens S, Giugliano RP, Torchiana D, Daggett W, Schwarz R, Jang IK. Comparison of Argatroban and Hirudin for the Reperfusion of Thrombotic Arterial Occlusion by Tissue Plasminogen Activator. J Thromb Thrombolysis. 1998 Sep; 6(2):103-108. PMID: 10751791.
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  274. Seckler JI, Butte A, Harrell L, Palacios I, Jang IK. Acute Occlusion During Coronary Interventions: The Changing Pattern in the Era of Stents. J Invasive Cardiol. 1998 May; 10(4):208-212. PMID: 10973343.
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  275. Mahdi NA, Lopez J, Leon M, Pathan A, Harrell L, Jang IK, Palacios IF. Comparison of primary coronary stenting to primary balloon angioplasty with stent bailout for the treatment of patients with acute myocardial infarction. Am J Cardiol. 1998 Apr 15; 81(8):957-63. PMID: 9576153.
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  276. Toussaint JF, Southern JF, Kantor HL, Jang IK, Fuster V. Behavior of atherosclerotic plaque components after in vitro angioplasty and atherectomy studied by high field MR imaging. Magn Reson Imaging. 1998; 16(2):175-83. PMID: 9508274.
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  277. Serebruany VL, Jang IK, Giugliano RP, Massey TJ, Schwarz Jr . A Randomized, Blinded Study of Two Doses of Novastan(R) (Brand of Argatroban) Versus Heparin as Adjunctive Therapy to Recombinant Tissue Plasminogen Activator (Accelerated Administration) in Acute Myocardial Infarction: Rationale and Design of the Myocardial Infarction using Novastan(R) and T-PA (MINT) Study. J Thromb Thrombolysis. 1998; 5(1):49-52. PMID: 10608050.
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  278. Butte AN, Houng AK, Jang IK, Reed GL. Alpha 2-antiplasmin causes thrombi to resist fibrinolysis induced by tissue plasminogen activator in experimental pulmonary embolism. Circulation. 1997 Apr 01; 95(7):1886-91. PMID: 9107177.
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  279. Grabowski EF, Jang IK, Gold H, Head C, Benoit SE, Michelson AD. Variability of platelet degranulation by different contrast media. Acad Radiol. 1996 Sep; 3 Suppl 3:S485-7. PMID: 8883525.
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  280. Grabowski EF, Boor SE, Rodino LJ, Jang IK, Gold H, Michelson AD. Platelets are degranulated by some, but not all, contrast media. Acad Radiol. 1996 Aug; 3 Suppl 2:S328-30. PMID: 8796594.
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  281. Smith AJ, Holt RE, Fitzpatrick JB, Palacios IF, Gold HK, Werner W, Bovill EG, Fuster V, Jang IK. Transient thrombotic state after abrupt discontinuation of heparin in percutaneous coronary angioplasty. Am Heart J. 1996 Mar; 131(3):434-9. PMID: 8604621.
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  282. Moreu J, Silver MT, Palacios IF, Jang IK. Morphologic characteristics of restenotic lesions following coronary interventions: balloon angioplasty versus directional atherectomy: can we speculate about the mechanism of restenosis from morphologic analysis? Cathet Cardiovasc Diagn. 1995 Oct; 36(2):103-9; discussion 110-1. PMID: 8829829.
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  283. Jang IK, Block PC, Newell JB, Tuzcu EM, Palacios IF. Percutaneous mitral balloon valvotomy for recurrent mitral stenosis after surgical commissurotomy. Am J Cardiol. 1995 Mar 15; 75(8):601-5. PMID: 7887386.
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  284. Aubert AE, Jang IK, Brzostek T, Van de Werf F, De Geest H. Determinants of transmitral inflow pattern 10-14 days after acute myocardial infarction. Coron Artery Dis. 1995 Feb; 6(2):137-45. PMID: 7780619.
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  285. Grabowski EF, Jang IK, Gold H, Palacios IF, Boor SE, Rodino LJ, Michelson AD. Platelet degranulation induced by some contrast media is independent of their nonionic vs ionic nature. Acta Radiol Suppl. 1995; 399:182-4. PMID: 8610512.
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  286. Cigarroa JE, Midha S, Jang IK. Directional atherectomy, rotational atherectomy and coronary stent, followed by coronary bypass operation in a patient with the aggressive restenotic process. Acta Cardiol. 1995; 50(6):469-75. PMID: 8932567.
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  287. Grabowski EF, Head C, Michail HA, Jang IK, Gold H, Benoit SE, Michelson AD. Effects of contrast media on platelet activation using flowing whole blood aggregometry and flow cytometry of platelet membrane glycoproteins. Invest Radiol. 1994 Jun; 29 Suppl 2:S198-200. PMID: 7928228.
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  288. Jang IK. Images in clinical medicine. Acute myocardial infarction and coronary spasm. N Engl J Med. 1994 May 19; 330(20):1420. PMID: 8159196.
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  289. Moreno PR, Jang IK, Newell JB, Block PC, Palacios IF. The role of percutaneous aortic balloon valvuloplasty in patients with cardiogenic shock and critical aortic stenosis. J Am Coll Cardiol. 1994 Apr; 23(5):1071-5. PMID: 8144770.
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  290. Fernández-Ortiz A, Jang IK, Fuster V. Antiplatelet and antithrombin therapy. Coron Artery Dis. 1994 Apr; 5(4):297-305. PMID: 8044341.
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  291. Kiss RG, Lu HR, Roskams T, Jang IK, Plow EF, Gold HK, Collen D. Time course of the effects of a single bolus injection of F(ab')2 fragments of the antiplatelet GPIIb/IIIa antibody 7E3 on arterial eversion graft occlusion, platelet aggregation, and bleeding time in dogs. Arterioscler Thromb. 1994 Mar; 14(3):367-74. PMID: 8123640.
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  292. Jang IK, Lassila R, Fuster V. Atherogenesis and inflammation. Eur Heart J. 1993 Dec; 14 Suppl K:2-6. PMID: 8131783.
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  293. Gold HK, Torres FW, Garabedian HD, Werner W, Jang IK, Khan A, Hagstrom JN, Yasuda T, Leinbach RC, Newell JB, et al. Evidence for a rebound coagulation phenomenon after cessation of a 4-hour infusion of a specific thrombin inhibitor in patients with unstable angina pectoris. J Am Coll Cardiol. 1993 Apr; 21(5):1039-47. PMID: 8459055.
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  294. Curwin J, Jang IK, Fuster V. Expanded use of thrombolytic therapy. Mayo Clin Proc. 1992 Oct; 67(10):1004-5. PMID: 1434847.
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  295. Jang IK, Gold HK, Leinbach RC, Fallon JT, Collen D, Wilcox JN. Antithrombotic effect of a monoclonal antibody against tissue factor in a rabbit model of platelet-mediated arterial thrombosis. Arterioscler Thromb. 1992 Aug; 12(8):948-54. PMID: 1637793.
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  296. Jang IK, Gold HK. Angioscopic evaluation of coronary-artery thrombi in acute coronary syndromes. N Engl J Med. 1992 Jul 16; 327(3):206-7. PMID: 1608426.
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  297. Gold HK, Yasuda T, Jang IK, Guerrero JL, Fallon JT, Leinbach RC, Collen D. Animal models for arterial thrombolysis and prevention of reocclusion. Erythrocyte-rich versus platelet-rich thrombus. Circulation. 1991 Jun; 83(6 Suppl):IV26-40. PMID: 2040069.
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  298. Yasuda T, Gold HK, Leinbach RC, Saito T, Guerrero JL, Jang IK, Holt R, Fallon JT, Collen D. Lysis of plasminogen activator-resistant platelet-rich coronary artery thrombus with combined bolus injection of recombinant tissue-type plasminogen activator and antiplatelet GPIIb/IIIa antibody. J Am Coll Cardiol. 1990 Dec; 16(7):1728-35. PMID: 2123910.
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  299. Jang IK, Gold HK, Leinbach RC, Fallon JT, Collen D. In vivo thrombin inhibition enhances and sustains arterial recanalization with recombinant tissue-type plasminogen activator. Circ Res. 1990 Dec; 67(6):1552-61. PMID: 2123135.
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  300. Vanhaecke J, Flameng W, Borgers M, Jang IK, Van de Werf F, De Geest H. Evidence for decreased coronary flow reserve in viable postischemic myocardium. Circ Res. 1990 Nov; 67(5):1201-10. PMID: 2225354.
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  301. Yasuda T, Gold HK, Yaoita H, Leinbach RC, Guerrero JL, Jang IK, Holt R, Fallon JT, Collen D. Comparative effects of aspirin, a synthetic thrombin inhibitor and a monoclonal antiplatelet glycoprotein IIb/IIIa antibody on coronary artery reperfusion, reocclusion and bleeding with recombinant tissue-type plasminogen activator in a canine preparation. J Am Coll Cardiol. 1990 Sep; 16(3):714-22. PMID: 2117620.
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  302. Jang IK, van de Werf F, Vanhaecke J, Aubert A, De Geest H. Comparison of angiographic methods for the assessment of the extent of experimental anterior myocardial infarction in dog hearts. Int J Cardiol. 1990 Aug; 28(2):179-90. PMID: 1975569.
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  303. Jang IK, Gold HK, Ziskind AA, Leinbach RC, Fallon JT, Collen D. Prevention of platelet-rich arterial thrombosis by selective thrombin inhibition. Circulation. 1990 Jan; 81(1):219-25. PMID: 2297828.
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  304. Jang IK, Van de Werf F, Vanhaecke J, De Geest H. Coronary reperfusion by thrombolysis and early beta-adrenergic blockade in acute experimental myocardial infarction. J Am Coll Cardiol. 1989 Dec; 14(7):1816-23. PMID: 2511233.
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  305. Jang IK, Gold HK, Ziskind AA, Fallon JT, Holt RE, Leinbach RC, May JW, Collen D. Differential sensitivity of erythrocyte-rich and platelet-rich arterial thrombi to lysis with recombinant tissue-type plasminogen activator. A possible explanation for resistance to coronary thrombolysis. Circulation. 1989 Apr; 79(4):920-8. PMID: 2494006.
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  306. Jang IK, van de Werf F, Vanhaecke J, Flameng W, De Geest H. Long term spontaneous evolution of left ventricular function after experimental acute coronary occlusion. Cardiovasc Res. 1988 Jul; 22(7):501-4. PMID: 3252972.
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  307. Van de Werf F, Vanhaecke J, Jang IK, Flameng W, Collen D, De Geest H. Reduction in infarct size and enhanced recovery of systolic function after coronary thrombolysis with tissue-type plasminogen activator combined with beta-adrenergic blockade with metoprolol. Circulation. 1987 Apr; 75(4):830-6. PMID: 3103951.
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  308. Van de Werf F, Jang IK, Collen D. Thrombolysis with recombinant human single-chain urokinase-type plasminogen activator (rscu-PA): dose-response in dogs with coronary artery thrombosis. J Cardiovasc Pharmacol. 1987 Jan; 9(1):91-3. PMID: 2434801.
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  309. Jang IK, Vanhaecke J, De Geest H, Verstraete M, Collen D, Van de Werf F. Coronary thrombolysis with recombinant tissue-type plasminogen activator: patency rate and regional wall motion after 3 months. J Am Coll Cardiol. 1986 Dec; 8(6):1455-60. PMID: 3097099.
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  310. Collen D, Stump D, van de Werf F, Jang IK, Nobuhara M, Lijnen HR. Coronary thrombolysis in dogs with intravenously administered human pro-urokinase. Circulation. 1985 Aug; 72(2):384-8. PMID: 3924437.
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