Harvard Catalyst Profiles

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Gilbert Rahme, Ph.D.


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  1. F32CA236432 (RAHME, GILBERT J) Jan 1, 2019 - Dec 31, 2021
    Epigenetic Induction of Gliomagenesis in Neural Progenitor Cells
    Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kim KL, van Galen P, Hovestadt V, Rahme GJ, Andreishcheva EN, Shinde A, Gaskell E, Jones DR, Shema E, Bernstein BE. Systematic detection of m6A-modified transcripts at single-molecule and single-cell resolution. Cell Rep Methods. 2021 Sep 27; 1(5). PMID: 34734208.
  2. Jenkins TW, Downey-Kopyscinski SL, Fields JL, Rahme GJ, Colley WC, Israel MA, Maksimenko AV, Fiering SN, Kisselev AF. Activity of immunoproteasome inhibitor ONX-0914 in acute lymphoblastic leukemia expressing MLL-AF4 fusion protein. Sci Rep. 2021 05 25; 11(1):10883. PMID: 34035431.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  3. Kim IS, Wu J, Rahme GJ, Battaglia S, Dixit A, Gaskell E, Chen H, Pinello L, Bernstein BE. Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies. Cell Rep. 2020 10 06; 33(1):108222. PMID: 33027665.
    Citations: 5     Fields:    Translation:HumansCells
  4. Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà ML. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. 2019 08 08; 178(4):835-849.e21. PMID: 31327527; PMCID: PMC6703186.
    Citations: 428     Fields:    Translation:HumansAnimalsCells
  5. Rahme GJ, Gaskell E, Bernstein BE. GABPß1L Wakes Up TERT. Cancer Cell. 2018 09 10; 34(3):358-360. PMID: 30205042.
    Citations:    Fields:    Translation:HumansCells
  6. Rahme GJ, Luikart BW, Cheng C, Israel MA. A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma. Neuro Oncol. 2018 02 19; 20(3):332-342. PMID: 29016807; PMCID: PMC5817944.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  7. Howe JR, Li ES, Streeter SE, Rahme GJ, Chipumuro E, Russo GB, Litzky JF, Hills LB, Rodgers KR, Skelton PD, Luikart BW. MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation. PLoS One. 2017; 12(5):e0177661. PMID: 28493990.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  8. Zhang Z, Rahme GJ, Chatterjee PD, Havrda MC, Israel MA. ID2 promotes survival of glioblastoma cells during metabolic stress by regulating mitochondrial function. Cell Death Dis. 2017 02 16; 8(2):e2615. PMID: 28206987.
    Citations: 10     Fields:    Translation:HumansCells
  9. Thomas AA, Fisher JL, Hampton TH, Christensen BC, Tsongalis GJ, Rahme GJ, Whipple CA, Steel SE, Davis MC, Gaur AB, Lewis LD, Ernstoff MS, Fadul CE. Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma. Cancer Immunol Immunother. 2017 Mar; 66(3):379-389. PMID: 27942839.
    Citations: 12     Fields:    Translation:HumansCells
  10. Glod J, Rahme GJ, Kaur H, H Raabe E, Hwang EI, Israel MA. Pediatric Brain Tumors: Current Knowledge and Therapeutic Opportunities. J Pediatr Hematol Oncol. 2016 05; 38(4):249-60. PMID: 26989915; PMCID: PMC5003110.
    Citations: 8     Fields:    Translation:Humans
  11. Rahme GJ, Zhang Z, Young AL, Cheng C, Bivona EJ, Fiering SN, Hitoshi Y, Israel MA. PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells. Cancer Res. 2016 05 15; 76(10):2964-76. PMID: 26951930.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  12. Thomas AA, Fisher JL, Rahme GJ, Hampton TH, Baron U, Olek S, Schwachula T, Rhodes CH, Gui J, Tafe LJ, Tsongalis GJ, Lefferts JA, Wishart H, Kleen J, Miller M, Whipple CA, de Abreu FB, Ernstoff MS, Fadul CE. Regulatory T cells are not a strong predictor of survival for patients with glioblastoma. Neuro Oncol. 2015 Jun; 17(6):801-9. PMID: 25618892; PMCID: PMC4483125.
    Citations: 22     Fields:    Translation:HumansCells
  13. Rahme GJ, Israel MA. Id4 suppresses MMP2-mediated invasion of glioblastoma-derived cells by direct inactivation of Twist1 function. Oncogene. 2015 Jan 02; 34(1):53-62. PMID: 24413082.
    Citations: 34     Fields:    Translation:HumansCells
  14. Mao P, Hever-Jardine MP, Rahme GJ, Yang E, Tam J, Kodali A, Biswal B, Fadul CE, Gaur A, Israel MA, Spinella MJ. Serine/threonine kinase 17A is a novel candidate for therapeutic targeting in glioblastoma. PLoS One. 2013; 8(11):e81803. PMID: 24312360; PMCID: PMC3842963.
    Citations: 12     Fields:    Translation:HumansCells
  15. Talhouk RS, Fares MB, Rahme GJ, Hariri HH, Rayess T, Dbouk HA, Bazzoun D, Al-Labban D, El-Sabban ME. Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: role of ß-catenin/connexin43 association. Exp Cell Res. 2013 Dec 10; 319(20):3065-80. PMID: 24120736.
    Citations: 26     Fields:    Translation:HumansCells
  16. Talhouk RS, Khalil AA, Bajjani R, Rahme GJ, El-Sabban ME. Gap junctions mediate STAT5-independent ß-casein expression in CID-9 mammary epithelial cells. Cell Commun Adhes. 2011 Oct; 18(5):104-16. PMID: 22142338.
    Citations: 2     Fields:    Translation:AnimalsCells
  17. Ramabhadran V, Korobova F, Rahme GJ, Higgs HN. Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture. Mol Biol Cell. 2011 Dec; 22(24):4822-33. PMID: 21998196.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.