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Jun R Huh, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hang S, Paik D, Yao L, Kim E, Trinath J, Lu J, Ha S, Nelson BN, Kelly SP, Wu L, Zheng Y, Longman RS, Rastinejad F, Devlin AS, Krout MR, Fischbach MA, Littman DR, Huh JR. Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2020 03; 579(7798):E7. PMID: 32094662.
    Citations:    
  2. Cho HS, Ha S, Shin HM, Reboldi A, Hall JA, Huh JR, Usherwood EJ, Berg LJ. CD8+ T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. Immunohorizons. 2020 02 07; 4(2):57-71. PMID: 32034085.
    Citations:    
  3. Reed MD, Yim YS, Wimmer RD, Kim H, Ryu C, Welch GM, Andina M, King HO, Waisman A, Halassa MM, Huh JR, Choi GB. IL-17a promotes sociability in mouse models of neurodevelopmental disorders. Nature. 2020 01; 577(7789):249-253. PMID: 31853066.
    Citations:    
  4. Huh JR, Veiga-Fernandes H. Neuroimmune circuits in inter-organ communication. Nat Rev Immunol. 2020 04; 20(4):217-228. PMID: 31848462.
    Citations:    
  5. Lee S, Song Y, Ko Y, Ko Y, Ko J, Kwon CH, Huh J, Kim SW, Yeom B, Cho J. A Metal-Like Conductive Elastomer with a Hierarchical Wrinkled Structure. Adv Mater. 2020 Feb; 32(7):e1906460. PMID: 31830359.
    Citations:    
  6. Lai NY, Musser MA, Pinho-Ribeiro FA, Baral P, Jacobson A, Ma P, Potts DE, Chen Z, Paik D, Soualhi S, Yan Y, Misra A, Goldstein K, Lagomarsino VN, Nordstrom A, Sivanathan KN, Wallrapp A, Kuchroo VK, Nowarski R, Starnbach MN, Shi H, Surana NK, An D, Wu C, Huh JR, Rao M, Chiu IM. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020 01 09; 180(1):33-49.e22. PMID: 31813624.
    Citations:    
  7. Hang S, Paik D, Yao L, Kim E, Trinath J, Lu J, Ha S, Nelson BN, Kelly SP, Wu L, Zheng Y, Longman RS, Rastinejad F, Devlin AS, Krout MR, Fischbach MA, Littman DR, Huh JR. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019 12; 576(7785):143-148. PMID: 31776512.
    Citations:    
  8. Kim E, Huh JR. NMD Takes the Immune Road to NDD. Neuron. 2019 11 20; 104(4):625-626. PMID: 31751540.
    Citations:    
  9. Hang S, Huh JR. The Immune-Mind Connection. Cell. 2019 10 31; 179(4):803-805. PMID: 31675492.
    Citations:    
  10. Kim HJ, Kim BG, Park JE, Ki CS, Huh J, Youm JB, Kang JS, Cho H. Characterization of a novel LQT3 variant with a selective efficacy of mexiletine treatment. Sci Rep. 2019 09 10; 9(1):12997. PMID: 31506521.
    Citations:    
  11. Park H, Song J, Kim ES, Huh J, Kang IS. Erratum: Early Experiences Using Cocoon Occluders for Closure of a Ventricular Septal Defect. J Cardiovasc Imaging. 2018 Dec; 26(4):256-257. PMID: 30607396.
    Citations:    
  12. Chen Y, Sharma S, Assis PA, Jiang Z, Elling R, Olive AJ, Hang S, Bernier J, Huh JR, Sassetti CM, Knipe DM, Gazzinelli RT, Fitzgerald KA. CNBP controls IL-12 gene transcription and Th1 immunity. J Exp Med. 2018 12 03; 215(12):3136-3150. PMID: 30442645.
    Citations:    Fields:    
  13. Park H, Song J, Kim ES, Huh J, Kang IS. Early Experiences Using Cocoon Occluders for Closure of a Ventricular Septal Defect. J Cardiovasc Imaging. 2018 Sep; 26(3):165-174. PMID: 30310884.
    Citations:    
  14. Tusi BK, Wolock SL, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, Waisman A, Huh JR, Klein AM, Socolovsky M. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018 03 01; 555(7694):54-60. PMID: 29466336.
    Citations: 6     Fields:    Translation:AnimalsCells
  15. Kim JH, Lee E, Friedline RH, Suk S, Jung DY, Dagdeviren S, Hu X, Inashima K, Noh HL, Kwon JY, Nambu A, Huh JR, Han MS, Davis RJ, Lee AS, Lee KW, Kim JK. Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity. FASEB J. 2018 04; 32(4):2292-2304. PMID: 29242277.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Choi YS, Jung MK, Lee J, Choi SJ, Choi SH, Lee HW, Lee JJ, Kim HJ, Ahn SH, Lee DH, Kim W, Park SH, Huh JR, Kim HP, Park JY, Shin EC. Tumor Necrosis Factor-producing T-regulatory Cells Are Associated With Severe Liver Injury in Patients With Acute Hepatitis A. Gastroenterology. 2018 03; 154(4):1047-1060. PMID: 29229400.
    Citations:    Fields:    Translation:HumansCells
  17. Kim S, Kim H, Yim YS, Ha S, Atarashi K, Tan TG, Longman RS, Honda K, Littman DR, Choi GB, Huh JR. Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring. Nature. 2017 09 28; 549(7673):528-532. PMID: 28902840.
    Citations: 19     Fields:    Translation:AnimalsCells
  18. Shin Yim Y, Park A, Berrios J, Lafourcade M, Pascual LM, Soares N, Yeon Kim J, Kim S, Kim H, Waisman A, Littman DR, Wickersham IR, Harnett MT, Huh JR, Choi GB. Reversing behavioural abnormalities in mice exposed to maternal inflammation. Nature. 2017 09 28; 549(7673):482-487. PMID: 28902835.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  19. Silverstein NJ, Huh JR. Interleukin-17: Why the Worms Squirm. Immunity. 2017 03 21; 46(3):347-349. PMID: 28329701.
    Citations:    Fields:    Translation:AnimalsCells
  20. Guerra ES, Lee CK, Specht CA, Yadav B, Huang H, Akalin A, Huh JR, Mueller C, Levitz SM. Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog. 2017 01; 13(1):e1006175. PMID: 28095479.
    Citations: 8     Fields:    Translation:AnimalsCells
  21. Kim HY, Jang SY, Moon JR, Kim EK, Chang SA, Song J, Huh J, Kang IS, Yang JH, Jun TG, Park SW. Natural Course of Adult Ebstein Anomaly When Treated according to Current Recommendation. J Korean Med Sci. 2016 Nov; 31(11):1749-1754. PMID: 27709852.
    Citations:    
  22. Lim AY, Song JS, Kim EK, Jang SY, Chung TY, Choi SH, Sung K, Huh J, Kang IS, Choe YH, Ki CS, Kim DK. Clinical Characteristics of Marfan Syndrome in Korea. Korean Circ J. 2016 Nov; 46(6):841-845. PMID: 27826344.
    Citations:    
  23. Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, Huh JR. The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science. 2016 Feb 26; 351(6276):933-9. PMID: 26822608.
    Citations: 78     Fields:    Translation:AnimalsCells
  24. Sellars M, Huh JR, Day K, Issuree PD, Galan C, Gobeil S, Absher D, Green MR, Littman DR. Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages. Nat Immunol. 2015 Jul; 16(7):746-54. PMID: 26030024.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  25. Longman RS, Diehl GE, Victorio DA, Huh JR, Galan C, Miraldi ER, Swaminath A, Bonneau R, Scherl EJ, Littman DR. CX3CR1? mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J Exp Med. 2014 Jul 28; 211(8):1571-83. PMID: 25024136.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  26. Yi SH, Kim SJ, Huh J, Jun TG, Cheon HJ, Kwon JY. Dysphagia in infants after open heart procedures. Am J Phys Med Rehabil. 2013 Jun; 92(6):496-503. PMID: 23478454.
    Citations: 3     Fields:    Translation:Humans
  27. Huh JR, Englund EE, Wang H, Huang R, Huang P, Rastinejad F, Inglese J, Austin CP, Johnson RL, Huang W, Littman DR. Identification of Potent and Selective Diphenylpropanamide ROR? Inhibitors. ACS Med Chem Lett. 2013 Jan 10; 4(1):79-84. PMID: 24040486.
    Citations: 11     
  28. Huh JR, Littman DR. Small molecule inhibitors of ROR?t: targeting Th17 cells and other applications. Eur J Immunol. 2012 Sep; 42(9):2232-7. PMID: 22949321.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  29. Kim SK, Huh J, Kim SY, Byun Y, Lee DY, Moon HT. Physicochemical conjugation with deoxycholic acid and dimethylsulfoxide for heparin oral delivery. Bioconjug Chem. 2011 Jul 20; 22(7):1451-8. PMID: 21627301.
    Citations: 2     Fields:    Translation:AnimalsCells
  30. Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing ROR?t activity. Nature. 2011 Apr 28; 472(7344):486-90. PMID: 21441909.
    Citations: 156     Fields:    Translation:HumansAnimalsCells
  31. Huh JR, Foe I, Muro I, Chen CH, Seol JH, Yoo SJ, Guo M, Park JM, Hay BA. The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. J Biol Chem. 2007 Jan 19; 282(3):2056-68. PMID: 17068333.
    Citations: 32     Fields:    Translation:AnimalsCells
  32. Muro I, Berry DL, Huh JR, Chen CH, Huang H, Yoo SJ, Guo M, Baehrecke EH, Hay BA. The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. Development. 2006 Sep; 133(17):3305-15. PMID: 16887831.
    Citations: 56     Fields:    Translation:AnimalsCells
  33. Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature. 2006 Jun 29; 441(7097):1162-6. PMID: 16672981.
    Citations: 550     Fields:    Translation:HumansAnimalsCells
  34. Yan N, Huh JR, Schirf V, Demeler B, Hay BA, Shi Y. Structure and activation mechanism of the Drosophila initiator caspase Dronc. J Biol Chem. 2006 Mar 31; 281(13):8667-74. PMID: 16446367.
    Citations: 13     Fields:    Translation:AnimalsCells
  35. Hay BA, Huh JR, Guo M. The genetics of cell death: approaches, insights and opportunities in Drosophila. Nat Rev Genet. 2004 Dec; 5(12):911-22. PMID: 15573123.
    Citations: 24     Fields:    Translation:Animals
  36. Huh JR, Guo M, Hay BA. Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role. Curr Biol. 2004 Jul 27; 14(14):1262-6. PMID: 15268856.
    Citations: 102     Fields:    Translation:AnimalsCells
  37. Huh JR, Vernooy SY, Yu H, Yan N, Shi Y, Guo M, Hay BA. Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol. 2004 Jan; 2(1):E15. PMID: 14737191.
    Citations: 55     Fields:    Translation:AnimalsCells
  38. Chai J, Yan N, Huh JR, Wu JW, Li W, Hay BA, Shi Y. Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. Nat Struct Biol. 2003 Nov; 10(11):892-8. PMID: 14517550.
    Citations: 48     Fields:    Translation:AnimalsCells
  39. Choi HS, Huh J, Jo WH. Similarity of force-induced unfolding of apomyoglobin to its chemical-induced unfolding: an atomistic molecular dynamics simulation approach. Biophys J. 2003 Sep; 85(3):1492-502. PMID: 12944267.
    Citations: 1     Fields:    Translation:AnimalsCells
  40. Olson MR, Holley CL, Yoo SJ, Huh JR, Hay BA, Kornbluth S. Reaper is regulated by IAP-mediated ubiquitination. J Biol Chem. 2003 Feb 07; 278(6):4028-34. PMID: 12446669.
    Citations: 17     Fields:    Translation:AnimalsCells
  41. Huh JR, Hay BA. Apoptosis: sculpture of a fly's head. Nature. 2002 Aug 29; 418(6901):926-8. PMID: 12198529.
    Citations:    Fields:    Translation:Animals
  42. Yoo SJ, Huh JR, Muro I, Yu H, Wang L, Wang SL, Feldman RM, Clem RJ, Müller HA, Hay BA. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol. 2002 Jun; 4(6):416-24. PMID: 12021767.
    Citations: 106     Fields:    Translation:AnimalsCells
  43. Dorstyn L, Read S, Cakouros D, Huh JR, Hay BA, Kumar S. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. J Cell Biol. 2002 Mar 18; 156(6):1089-98. PMID: 11901173.
    Citations: 49     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.