Harvard Catalyst Profiles

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Hassan A Khalil, M.D.


University of Texas at Houston, Houston, TXMD05/2010Medicine
University of California, Los Angeles, Los Angeles, CA05/2017General Surgery
Brigham & Women's Hospital, Boston, MA06/2018Thoracic Surgery

Available: 12/01/22, Expires: 12/01/23

Esophageal and bowel anastomotic leaks are devastating complications after surgery. Our lab studies how vacuum (in the form of microdeformation) affects healing of intestinal anastomotic healing in an animal model, but in vitro model would be helpful. A creative student investigator can initiate an in vitro model system to study microdeformation in my laboratory. The role will include learning how to grow and sustain chick embryos in culture, and potentially some cell culture work. The student will have an opportunity to learn immunofluorescence, microscopy, and quantitative PCR.

Available: 12/01/22, Expires: 11/01/23

Classically, lung cancer has been known to metastasize via lymphatic or hematogenous spread. A more recently discovered metastatic pathway is spread through air spaces, possibly related to tumor discohesion and implantation of tumor cells away from the primary tumor. My laboratory investigates this mode of spread via histology, high resolution X-ray imaging, and other methods. It's an exciting field with little known and great potential for discovery. The role will include working with a clinical database, using statistical methods, and analyzing advanced imaging data including histology and high-resolution X-rays.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.