Harvard Catalyst Profiles

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Jussi Jaakko Saukkonen, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL062977 (SAUKKONEN, JUSSI J) Sep 30, 1999 - Aug 31, 2004
    NIH
    CHEMOKINES IN HOST RESPONSE TO MYCOBACTERIAL INFECTION
    Role: Principal Investigator
  2. R29HL053249 (SAUKKONEN, JUSSI J) Aug 1, 1994 - Jul 31, 1999
    NIH
    PATHOGENESIS OF HIV ALVEOLITIS AND ROLE OF A CD8 SUBSET
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wilson KC, Schoenberg NC, Cohn DL, Crothers K, Fennelly KP, Metlay JP, Saukkonen JJ, Strange C, Waterer G, Dweik R. Community-acquired Pneumonia Guideline Recommendations-Impact of a Consensus-based Process versus Systematic Reviews. Clin Infect Dis. 2021 10 05; 73(7):e1467-e1475. PMID: 32964218.
    Citations:    Fields:    Translation:Humans
  2. Hedges KNC, Borisov AS, Saukkonen JJ, Scott NA, Hecker EJ, Bozeman L, Dukes Hamilton C, Kerrigan A, Bessler P, Moreno-Martinez A, Arevalo B, Goldberg SV. Nonparticipation reasons in a randomized international trial of a new latent tuberculosis infection regimen. Clin Trials. 2020 02; 17(1):39-51. PMID: 31690107; PMCID: PMC9446162.
    Citations:    Fields:    Translation:Humans
  3. Moro RN, Sterling TR, Saukkonen J, Vernon A, Horsburgh CR, Chaisson RE, Hamilton CD, Villarino ME, Goldberg S. Factors associated with non-completion of follow-up: 33-month latent tuberculous infection treatment trial. Int J Tuberc Lung Dis. 2017 03 01; 21(3):286-296. PMID: 28087928; PMCID: PMC6563818.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  4. Nahid P, Dorman SE, Alipanah N, Barry PM, Brozek JL, Cattamanchi A, Chaisson LH, Chaisson RE, Daley CL, Grzemska M, Higashi JM, Ho CS, Hopewell PC, Keshavjee SA, Lienhardt C, Menzies R, Merrifield C, Narita M, O'Brien R, Peloquin CA, Raftery A, Saukkonen J, Schaaf HS, Sotgiu G, Starke JR, Migliori GB, Vernon A. Executive Summary: Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis. Clin Infect Dis. 2016 10 01; 63(7):853-67. PMID: 27621353; PMCID: PMC6366011.
    Citations: 71     Fields:    Translation:HumansCellsPHPublic Health
  5. Nahid P, Dorman SE, Alipanah N, Barry PM, Brozek JL, Cattamanchi A, Chaisson LH, Chaisson RE, Daley CL, Grzemska M, Higashi JM, Ho CS, Hopewell PC, Keshavjee SA, Lienhardt C, Menzies R, Merrifield C, Narita M, O'Brien R, Peloquin CA, Raftery A, Saukkonen J, Schaaf HS, Sotgiu G, Starke JR, Migliori GB, Vernon A. Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis. Clin Infect Dis. 2016 10 01; 63(7):e147-e195. PMID: 27516382; PMCID: PMC6590850.
    Citations: 275     Fields:    Translation:HumansCellsPHPublic Health
  6. Moro RN, Borisov AS, Saukkonen J, Khan A, Sterling TR, Villarino ME, Scott NA, Shang N, Kerrigan A, Goldberg SV. Factors Associated With Noncompletion of Latent Tuberculosis Infection Treatment: Experience From the PREVENT TB Trial in the United States and Canada. Clin Infect Dis. 2016 06 01; 62(11):1390-1400. PMID: 26951571; PMCID: PMC6521957.
    Citations: 17     Fields:    Translation:Humans
  7. Jayakumar A, Vittinghoff E, Segal MR, MacKenzie WR, Johnson JL, Gitta P, Saukkonen J, Anderson J, Weiner M, Engle M, Yoon C, Kato-Maeda M, Nahid P. Serum biomarkers of treatment response within a randomized clinical trial for pulmonary tuberculosis. Tuberculosis (Edinb). 2015 Jul; 95(4):415-20. PMID: 26022314.
    Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
  8. Kane M, Korn B, Saukkonen J, McDonald C, Walsh C, Waters R, McLaughlin AM, Keane J. Barriers to accepting and completing latent tuberculosis infection treatment. Ir Med J. 2013 Jul-Aug; 106(7):200-4. PMID: 24218745.
    Citations: 1     Fields:    Translation:Humans
  9. Hales CM, Heilig CM, Chaisson R, Leung CC, Chang KC, Goldberg SV, Gordin F, Johnson JL, Muzanyi G, Saukkonen J, Vernon A, Villarino ME, Burman WJ. The association between symptoms and microbiologically defined response to tuberculosis treatment. Ann Am Thorac Soc. 2013 Feb; 10(1):18-25. PMID: 23509328.
    Citations: 13     Fields:    Translation:HumansCells
  10. Padayatchi N, Mac Kenzie WR, Hirsch-Moverman Y, Feng PJ, Villarino E, Saukkonen J, Heilig CM, Weiner M, El-Sadr WM. Lessons from a randomised clinical trial for multidrug-resistant tuberculosis. Int J Tuberc Lung Dis. 2012 Dec; 16(12):1582-7. PMID: 23131255.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  11. Goswami ND, Gadkowski LB, Piedrahita C, Bissette D, Ahearn MA, Blain ML, Østbye T, Saukkonen J, Stout JE. Predictors of latent tuberculosis treatment initiation and completion at a U.S. public health clinic: a prospective cohort study. BMC Public Health. 2012 Jun 21; 12:468. PMID: 22720842.
    Citations: 26     Fields:    Translation:Humans
  12. Lamunu D, Chapman KN, Nsubuga P, Muzanyi G, Mulumba Y, Mugerwa MA, Goldberg S, Bozeman L, Engle M, Saukkonen J, Mastranunzio S, Mayanja-Kizza H, Johnson JL. Reasons for non-participation in an international multicenter trial of a new drug for tuberculosis treatment. Int J Tuberc Lung Dis. 2012 Apr; 16(4):480-5. PMID: 22640513.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  13. Saukkonen JJ, Powell K, Jereb JA. Monitoring for tuberculosis drug hepatotoxicity: moving from opinion to evidence. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):598-9. PMID: 22422902.
    Citations: 6     Fields:    Translation:Humans
  14. Nahid P, Saukkonen J, Mac Kenzie WR, Johnson JL, Phillips PP, Andersen J, Bliven-Sizemore E, Belisle JT, Boom WH, Luetkemeyer A, Campbell TB, Eisenach KD, Hafner R, Lennox JL, Makhene M, Swindells S, Villarino ME, Weiner M, Benson C, Burman W. CDC/NIH Workshop. Tuberculosis biomarker and surrogate endpoint research roadmap. Am J Respir Crit Care Med. 2011 Oct 15; 184(8):972-9. PMID: 21737585; PMCID: PMC3208659.
    Citations: 34     Fields:    Translation:Humans
  15. O'Donnell MR, Coe A, Bliss C, Lee D, Tumilty S, Skolnik PR, Horsburgh CR, Cotton D, Saukkonen J. Acceptance of interferon-gamma release assay by a high-risk urban cohort. Int J Tuberc Lung Dis. 2011 Oct; 15(10):1334-9. PMID: 22283891.
    Citations:    Fields:    Translation:Humans
  16. Heilig CM, Chia D, El-Sadr WM, Hirsch-Moverman Y, Kenzie WR, Saukkonen J, Villarino ME, Padayatchi N. Justifying research risks in a clinical trial for treatment of multidrug-resistant tuberculosis. IRB. 2011 Jul-Aug; 33(4):10-7. PMID: 21932482.
    Citations: 2     Fields:    Translation:Humans
  17. Al Husseini AM, Lee HJ, Negrete J, Powelson S, Servi AT, Slocum AH, Saukkonen J. Design and Prototyping of a Low-Cost Portable Mechanical Ventilator. J Med Device. 2010 Jun 01; 4(2):027514. PMID: 32328214; PMCID: PMC7164497.
    Citations: 22     
  18. Saukkonen J. Challenges in reintroducing tuberculosis medications after hepatotoxicity. Clin Infect Dis. 2010 Mar 15; 50(6):840-2. PMID: 20156056.
    Citations: 1     Fields:    Translation:Humans
  19. Patel NR, Zhu J, Tachado SD, Zhang J, Wan Z, Saukkonen J, Koziel H. HIV impairs TNF-alpha mediated macrophage apoptotic response to Mycobacterium tuberculosis. J Immunol. 2007 Nov 15; 179(10):6973-80. PMID: 17982088.
    Citations: 48     Fields:    Translation:HumansCells
  20. Saukkonen JJ, Cohn DL, Jasmer RM, Schenker S, Jereb JA, Nolan CM, Peloquin CA, Gordin FM, Nunes D, Strader DB, Bernardo J, Venkataramanan R, Sterling TR. An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med. 2006 Oct 15; 174(8):935-52. PMID: 17021358.
    Citations: 270     Fields:    Translation:Humans
  21. Shieh FK, Snyder G, Horsburgh CR, Bernardo J, Murphy C, Saukkonen JJ. Predicting non-completion of treatment for latent tuberculous infection: a prospective survey. Am J Respir Crit Care Med. 2006 Sep 15; 174(6):717-21. PMID: 16809632.
    Citations: 34     Fields:    Translation:HumansPHPublic Health
  22. Parsyan AE, Saukkonen J, Barry MA, Sharnprapai S, Horsburgh CR. Predictors of failure to complete treatment for latent tuberculosis infection. J Infect. 2007 Mar; 54(3):262-6. PMID: 16772095.
    Citations: 19     Fields:    Translation:Humans
  23. Jasmer RM, Bozeman L, Schwartzman K, Cave MD, Saukkonen JJ, Metchock B, Khan A, Burman WJ. Recurrent tuberculosis in the United States and Canada: relapse or reinfection? Am J Respir Crit Care Med. 2004 Dec 15; 170(12):1360-6. PMID: 15477492.
    Citations: 55     Fields:    Translation:HumansCellsCTClinical Trials
  24. Saukkonen J. Rifampin and pyrazinamide for latent tuberculosis infection: clinical trials and general practice. Clin Infect Dis. 2004 Aug 15; 39(4):566-8. PMID: 15356823.
    Citations:    Fields:    Translation:Humans
  25. Wilson KC, Saukkonen JJ. Acute respiratory failure from abused substances. J Intensive Care Med. 2004 Jul-Aug; 19(4):183-93. PMID: 15296619.
    Citations: 27     Fields:    Translation:HumansAnimals
  26. Jasmer RM, Snyder DC, Saukkonen JJ, Hopewell PC, Bernardo J, King MD, Kawamura LM, Daley CL. Short-course rifampin and pyrazinamide compared with isoniazid for latent tuberculosis infection: a cost-effectiveness analysis based on a multicenter clinical trial. Clin Infect Dis. 2004 Feb 01; 38(3):363-9. PMID: 14727206.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  27. Jasmer RM, Saukkonen JJ, Blumberg HM, Daley CL, Bernardo J, Vittinghoff E, King MD, Kawamura LM, Hopewell PC. Short-course rifampin and pyrazinamide compared with isoniazid for latent tuberculosis infection: a multicenter clinical trial. Ann Intern Med. 2002 Oct 15; 137(8):640-7. PMID: 12379063.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  28. Saukkonen JJ, Bazydlo B, Thomas M, Strieter RM, Keane J, Kornfeld H. Beta-chemokines are induced by Mycobacterium tuberculosis and inhibit its growth. Infect Immun. 2002 Apr; 70(4):1684-93. PMID: 11895930.
    Citations: 48     Fields:    Translation:HumansCells
  29. Jones BW, Heldwein KA, Means TK, Saukkonen JJ, Fenton MJ. Differential roles of Toll-like receptors in the elicitation of proinflammatory responses by macrophages. Ann Rheum Dis. 2001 Nov; 60 Suppl 3:iii6-12. PMID: 11890657; PMCID: PMC1766663.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  30. Saukkonen JJ, Tantri A, Berman J. Costimulation of CD28- T cells through CD3 and beta1-integrins induces a limited Th1 cytokine response. Scand J Immunol. 1999 Aug; 50(2):145-9. PMID: 10447918.
    Citations: 1     Fields:    Translation:HumansCells
  31. Mashikian MV, Tarpy RE, Saukkonen JJ, Lim KG, Fine GD, Cruikshank WW, Center DM. Identification of IL-16 as the lymphocyte chemotactic activity in the bronchoalveolar lavage fluid of histamine-challenged asthmatic patients. J Allergy Clin Immunol. 1998 Jun; 101(6 Pt 1):786-92. PMID: 9648706.
    Citations: 5     Fields:    Translation:HumansCells
  32. Saukkonen JJ, Furfaro S, Mahoney KM, Strieter RM, Burdick M, Wright EA, Kornfeld H, Berman JS. In vitro transendothelial migration of blood T lymphocytes from HIV-infected individuals. AIDS. 1997 Nov; 11(13):1595-601. PMID: 9365764.
    Citations: 5     Fields:    Translation:HumansCells
  33. Hendra KP, Saukkonen JJ. Erosion of the right mainstem bronchus by an esophageal stent. Chest. 1996 Sep; 110(3):857-8. PMID: 8797444.
    Citations: 4     Fields:    Translation:Humans
  34. Berman JS, Mahoney K, Saukkonen JJ, Masuyama J. Migration of distinct subsets of CD8+ blood T cells through endothelial cell monolayers in vitro. J Leukoc Biol. 1995 Sep; 58(3):317-24. PMID: 7665987.
    Citations: 2     Fields:    Translation:HumansCells
  35. Saukkonen JJ, Kornfeld H, Berman JS. Expansion of a CD8+CD28- cell population in the blood and lung of HIV-positive patients. J Acquir Immune Defic Syndr (1988). 1993 Nov; 6(11):1194-204. PMID: 8229654.
    Citations: 23     Fields:    Translation:HumansCells
  36. Hollmén A, Saukkonen J. Postoperative serum glutamic-oxalacetic transaminase and glutamic-pyruvic transaminase changes in biliary patients. Acta Anaesthesiol Scand. 1967; 11(4):393-400. PMID: 5597538.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.