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Charles Allen Boucher, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nichols BE, Boucher CA, van Dijk JH, Thuma PE, Nouwen JL, Baltussen R, van de Wijgert J, Sloot PM, van de Vijver DA. Cost-effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV-1 infections in rural Zambia: a modeling study. PLoS One. 2013; 8(3):e59549. PMID: 23527217.
    Citations: 26     Fields:    Translation:HumansCellsPHPublic Health
  2. Abecasis AB, Wensing AM, Paraskevis D, Vercauteren J, Theys K, Van de Vijver DA, Albert J, Asjö B, Balotta C, Beshkov D, Camacho RJ, Clotet B, De Gascun C, Griskevicius A, Grossman Z, Hamouda O, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Stanekova D, Stanojevic M, Struck D, Boucher CA, Vandamme AM. HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics. Retrovirology. 2013 Jan 14; 10:7. PMID: 23317093.
    Citations: 62     Fields:    Translation:HumansCellsPHPublic Health
  3. Whitley RJ, Boucher CA, Lina B, Nguyen-Van-Tam JS, Osterhaus A, Schutten M, Monto AS. Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS). Clin Infect Dis. 2013 May; 56(9):1197-205. PMID: 23307766.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  4. Theys K, Deforche K, Vercauteren J, Libin P, van de Vijver DA, Albert J, Asjö B, Balotta C, Bruckova M, Camacho RJ, Clotet B, Coughlan S, Grossman Z, Hamouda O, Horban A, Korn K, Kostrikis LG, Kücherer C, Nielsen C, Paraskevis D, Poljak M, Puchhammer-Stockl E, Riva C, Ruiz L, Liitsola K, Schmit JC, Schuurman R, Sönnerborg A, Stanekova D, Stanojevic M, Struck D, Van Laethem K, Wensing AM, Boucher CA, Vandamme AM. Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients. Retrovirology. 2012 Oct 03; 9:81. PMID: 23031662.
    Citations: 15     Fields:    Translation:HumansCells
  5. van der Vries E, Collins PJ, Vachieri SG, Xiong X, Liu J, Walker PA, Haire LF, Hay AJ, Schutten M, Osterhaus AD, Martin SR, Boucher CA, Skehel JJ, Gamblin SJ. H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis. PLoS Pathog. 2012 Sep; 8(9):e1002914. PMID: 23028314; PMCID: PMC3447749.
    Citations: 38     Fields:    Translation:HumansCellsPHPublic Health
  6. Hoek RA, Paats MS, Pas SD, Bakker M, Hoogsteden HC, Boucher CA, van der Eerden MM. Incidence of viral respiratory pathogens causing exacerbations in adult cystic fibrosis patients. Scand J Infect Dis. 2013 Jan; 45(1):65-9. PMID: 22992129.
    Citations: 37     Fields:    Translation:HumansCells
  7. Rijckborst V, Ferenci P, Akdogan M, Pinarbasi B, ter Borg MJ, Simon K, Flisiak R, Akarca US, Raptopoulou-Gigi M, Verhey E, van Vuuren AJ, Boucher CA, Hansen BE, Janssen HL. Long-term follow-up of hepatitis B e antigen-negative patients treated with peginterferon a-2a: progressive decrease in hepatitis B surface antigen in responders. Eur J Gastroenterol Hepatol. 2012 Sep; 24(9):1012-9. PMID: 22668876.
    Citations: 3     Fields:    Translation:Humans
  8. Veldhuijzen IK, Wolter R, Rijckborst V, Mostert M, Voeten HA, Cheung Y, Boucher CA, Reijnders JG, de Zwart O, Janssen HL. Identification and treatment of chronic hepatitis B in Chinese migrants: results of a project offering on-site testing in Rotterdam, The Netherlands. J Hepatol. 2012 Dec; 57(6):1171-6. PMID: 22885717.
    Citations: 27     Fields:    Translation:Humans
  9. Pingen M, Nouwen JL, Dinant S, Albert J, Mild M, Brodin J, Simen BB, Walsh S, Kayser M, van der Ende ME, Schutten M, Boucher CA. Therapy failure resulting from superinfection by a drug-resistant HIV variant. Antivir Ther. 2012; 17(8):1621-5. PMID: 22846173.
    Citations: 8     Fields:    Translation:HumansCells
  10. Fibriani A, Farah N, Kusumadewi I, Pas SD, van Crevel R, van der Ven A, Boucher CA, Schutten M. Low cost HIV-1 quantitative RT-PCR assay in resource-limited settings: improvement and implementation. J Virol Methods. 2012 Oct; 185(1):118-23. PMID: 22766178.
    Citations: 2     Fields:    Translation:HumansCells
  11. van Maarseveen NM, Andersson D, Lepšík M, Fun A, Schipper PJ, de Jong D, Boucher CA, Nijhuis M. Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity. Retrovirology. 2012 Apr 01; 9:29. PMID: 22462820.
    Citations: 11     Fields:    Translation:HumansCells
  12. Verjans GM, Boucher CA. Aciclovir for dual infection with HIV and HSV. Lancet Infect Dis. 2012 Jun; 12(6):424-5. PMID: 22433278.
    Citations:    Fields:    Translation:HumansCells
  13. Sonneveld MJ, Rijckborst V, Cakaloglu Y, Simon K, Heathcote EJ, Tabak F, Mach T, Boucher CA, Hansen BE, Zeuzem S, Janssen HL. Durable hepatitis B surface antigen decline in hepatitis B e antigen-positive chronic hepatitis B patients treated with pegylated interferon-a2b: relation to response and HBV genotype. Antivir Ther. 2012; 17(1):9-17. PMID: 22267464.
    Citations: 19     Fields:    Translation:HumansCells
  14. Frentz D, Boucher CA, van de Vijver DA. Temporal changes in the epidemiology of transmission of drug-resistant HIV-1 across the world. AIDS Rev. 2012 Jan-Mar; 14(1):17-27. PMID: 22297501.
    Citations: 82     Fields:    Translation:HumansCells
  15. Dijkstra F, Jonges M, van Beek R, Donker GA, Schellevis FG, Koopmans M, van der Sande MA, Osterhaus AD, Boucher CA, Rimmelzwaan GF, Meijer A. Influenza A(H1N1) Oseltamivir Resistant Viruses in the Netherlands During the Winter 2007/2008. Open Virol J. 2011; 5:154-62. PMID: 22253652.
    Citations: 2     
  16. Frentz D, van de Vijver DA, Boucher CA, Albert J. Estimates of HIV transmitted drug resistance can be inflated due to natural sequence polymorphisms. J Acquir Immune Defic Syndr. 2011 Dec 15; 58(5):e135-7. PMID: 22075602.
    Citations: 3     Fields:    Translation:HumansCells
  17. van der Vries E, Schutten M, Boucher CA. The potential for multidrug-resistant influenza. Curr Opin Infect Dis. 2011 Dec; 24(6):599-604. PMID: 22001947.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  18. Nichols BE, Boucher CA, van de Vijver DA. HIV testing and antiretroviral treatment strategies for prevention of HIV infection: impact on antiretroviral drug resistance. J Intern Med. 2011 Dec; 270(6):532-49. PMID: 21929723.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  19. van der Vries E, Veldhuis Kroeze EJ, Stittelaar KJ, Linster M, Van der Linden A, Schrauwen EJ, Leijten LM, van Amerongen G, Schutten M, Kuiken T, Osterhaus AD, Fouchier RA, Boucher CA, Herfst S. Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets. PLoS Pathog. 2011 Sep; 7(9):e1002276. PMID: 21980293.
    Citations: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  20. Fraaij PL, van der Vries E, Beersma MF, Riezebos-Brilman A, Niesters HG, van der Eijk AA, de Jong MD, Reis Miranda D, Horrevorts AM, Ridwan BU, Wolfhagen MJ, Houmes RJ, van Dissel JT, Fouchier RA, Kroes AC, Koopmans MP, Osterhaus AD, Boucher CA. Evaluation of the antiviral response to zanamivir administered intravenously for treatment of critically ill patients with pandemic influenza A (H1N1) infection. J Infect Dis. 2011 Sep 01; 204(5):777-82. PMID: 21844304; PMCID: PMC3156108.
    Citations: 18     Fields:    Translation:HumansCells
  21. Zoutendijk R, Hansen BE, van Vuuren AJ, Boucher CA, Janssen HL. Serum HBsAg decline during long-term potent nucleos(t)ide analogue therapy for chronic hepatitis B and prediction of HBsAg loss. J Infect Dis. 2011 Aug 01; 204(3):415-8. PMID: 21742840.
    Citations: 33     Fields:    Translation:Humans
  22. Meijer A, Jonges M, Abbink F, Ang W, van Beek J, Beersma M, Bloembergen P, Boucher C, Claas E, Donker G, van Gageldonk-Lafeber R, Isken L, de Jong A, Kroes A, Leenders S, van der Lubben M, Mascini E, Niesters B, Oosterheert JJ, Osterhaus A, Riesmeijer R, Riezebos-Brilman A, Schutten M, Sebens F, Stelma F, Swaan C, Timen A, van 't Veen A, van der Vries E, te Wierik M, Koopmans M. Oseltamivir-resistant pandemic A(H1N1) 2009 influenza viruses detected through enhanced surveillance in the Netherlands, 2009-2010. Antiviral Res. 2011 Oct; 92(1):81-9. PMID: 21767571.
    Citations: 14     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  23. Sonneveld MJ, Rijckborst V, Boucher CA, Zwang L, Beersma MF, Hansen BE, Janssen HL. A comparison of two assays for quantification of Hepatitis B surface Antigen in patients with chronic hepatitis B. J Clin Virol. 2011 Jul; 51(3):175-8. PMID: 21592855.
    Citations: 11     Fields:    Translation:Humans
  24. Pingen M, Nijhuis M, de Bruijn JA, Boucher CA, Wensing AM. Evolutionary pathways of transmitted drug-resistant HIV-1. J Antimicrob Chemother. 2011 Jul; 66(7):1467-80. PMID: 21502281.
    Citations: 34     Fields:    Translation:HumansCells
  25. Vandekerckhove LP, Wensing AM, Kaiser R, Brun-Vézinet F, Clotet B, De Luca A, Dressler S, Garcia F, Geretti AM, Klimkait T, Korn K, Masquelier B, Perno CF, Schapiro JM, Soriano V, Sönnerborg A, Vandamme AM, Verhofstede C, Walter H, Zazzi M, Boucher CA. European guidelines on the clinical management of HIV-1 tropism testing. Lancet Infect Dis. 2011 May; 11(5):394-407. PMID: 21429803.
    Citations: 92     Fields:    Translation:HumansCells
  26. Mascolini M, Mellors JW, Richman DD, Boucher CA, Larder BA. HIV and hepatitis virus resistance to antivirals: review of data from the XIX International HIV and Hepatitis Virus Drug Resistance Workshop and curative strategies. Antivir Ther. 2011; 16(2):263-86. PMID: 21447877.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  27. Schapiro JM, Boucher CA, Kuritzkes DR, van de Vijver DA, Llibre JM, Lewis M, Simpson P, Delogne C, McFadyen L, Chapman D, Perros M, Valdez H, van der Ryst E, Westby M. Baseline CD4(+) T-cell counts and weighted background susceptibility scores strongly predict response to maraviroc regimens in treatment-experienced patients. Antivir Ther. 2011; 16(3):395-404. PMID: 21555822.
    Citations: 11     Fields:    Translation:HumansCells
  28. Stoye JP, Silverman RH, Boucher CA, Le Grice SF. The xenotropic murine leukemia virus-related retrovirus debate continues at first international workshop. Retrovirology. 2010 Dec 22; 7:113. PMID: 21176195.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  29. van de Vijver DA, Wensing AM, Åsjö B, Bruckova M, Jorgensen LB, Camacho R, Horban A, Linka M, Lazanas M, Loveday C, MacRae E, Nielsen C, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Ruiz L, Schmit JC, Stanczak G, Stanojevic M, Vandamme AM, Vercauteren J, Zazzi M, Bacheler L, Lecocq P, Villacian J, Boucher CA. HIV-1 drug-resistance patterns among patients on failing treatment in a large number of European countries. Acta Dermatovenerol Alp Pannonica Adriat. 2010 Dec; 19(4):3-9. PMID: 21390473.
    Citations: 4     Fields:    Translation:HumansCells
  30. van de Vijver DA, Boucher CA. The risk of HIV drug resistance following implementation of pre-exposure prophylaxis. Curr Opin Infect Dis. 2010 Dec; 23(6):621-7. PMID: 20847692.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  31. Reijnders JG, Rijckborst V, Sonneveld MJ, Scherbeijn SM, Boucher CA, Hansen BE, Janssen HL. Kinetics of hepatitis B surface antigen differ between treatment with peginterferon and entecavir. J Hepatol. 2011 Mar; 54(3):449-54. PMID: 21112655.
    Citations: 40     Fields:    Translation:Humans
  32. Schreuder I, van der Sande MA, de Wit M, Bongaerts M, Boucher CA, Croes EA, van Veen MG. Seroprevalence of HIV, hepatitis b, and hepatitis c among opioid drug users on methadone treatment in the netherlands. Harm Reduct J. 2010 Oct 26; 7:25. PMID: 20977742.
    Citations: 14     Fields:    
  33. Sonneveld MJ, Rijckborst V, Boucher CA, Hansen BE, Janssen HL. Prediction of sustained response to peginterferon alfa-2b for hepatitis B e antigen-positive chronic hepatitis B using on-treatment hepatitis B surface antigen decline. Hepatology. 2010 Oct; 52(4):1251-7. PMID: 20830787.
    Citations: 75     Fields:    Translation:HumansCells
  34. van der Vries E, Stelma FF, Boucher CA. Emergence of a multidrug-resistant pandemic influenza A (H1N1) virus. N Engl J Med. 2010 Sep 30; 363(14):1381-2. PMID: 20879894.
    Citations: 87     Fields:    Translation:HumansCellsPHPublic Health
  35. Zazzi M, Kaiser R, Sönnerborg A, Struck D, Altmann A, Prosperi M, Rosen-Zvi M, Petroczi A, Peres Y, Schülter E, Boucher CA, Brun-Vezinet F, Harrigan PR, Morris L, Obermeier M, Perno CF, Phanuphak P, Pillay D, Shafer RW, Vandamme AM, van Laethem K, Wensing AM, Lengauer T, Incardona F. Prediction of response to antiretroviral therapy by human experts and by the EuResist data-driven expert system (the EVE study). HIV Med. 2011 Apr; 12(4):211-8. PMID: 20731728.
    Citations: 13     Fields:    Translation:HumansCells
  36. Rijckborst V, Hansen BE, Cakaloglu Y, Ferenci P, Tabak F, Akdogan M, Simon K, Akarca US, Flisiak R, Verhey E, Van Vuuren AJ, Boucher CA, ter Borg MJ, Janssen HL. Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels. Hepatology. 2010 Aug; 52(2):454-61. PMID: 20683945.
    Citations: 50     Fields:    Translation:HumansCells
  37. van Dijk D, Ertaylan G, Boucher CA, Sloot PM. Identifying potential survival strategies of HIV-1 through virus-host protein interaction networks. BMC Syst Biol. 2010 Jul 15; 4:96. PMID: 20633292.
    Citations: 15     Fields:    Translation:HumansCells
  38. Frentz D, Boucher CA, Assel M, De Luca A, Fabbiani M, Incardona F, Libin P, Manca N, Müller V, O Nualláin B, Paredes R, Prosperi M, Quiros-Roldan E, Ruiz L, Sloot PM, Torti C, Vandamme AM, Van Laethem K, Zazzi M, van de Vijver DA. Comparison of HIV-1 genotypic resistance test interpretation systems in predicting virological outcomes over time. PLoS One. 2010 Jul 09; 5(7):e11505. PMID: 20634893.
    Citations: 31     Fields:    Translation:HumansCells
  39. Liu W, Li ZD, Tang F, Wei MT, Tong YG, Zhang L, Xin ZT, Ma MJ, Zhang XA, Liu LJ, Zhan L, He C, Yang H, Boucher CA, Richardus JH, Cao WC. Mixed infections of pandemic H1N1 and seasonal H3N2 viruses in 1 outbreak. Clin Infect Dis. 2010 May 15; 50(10):1359-65. PMID: 20380566.
    Citations: 24     Fields:    Translation:HumansCellsPHPublic Health
  40. Bui QC, Nualláin BO, Boucher CA, Sloot PM. Extracting causal relations on HIV drug resistance from literature. BMC Bioinformatics. 2010 Feb 23; 11:101. PMID: 20178611.
    Citations: 7     Fields:    
  41. Bezemer D, van Sighem A, Lukashov VV, van der Hoek L, Back N, Schuurman R, Boucher CA, Claas EC, Boerlijst MC, Coutinho RA, de Wolf F. Transmission networks of HIV-1 among men having sex with men in the Netherlands. AIDS. 2010 Jan 16; 24(2):271-82. PMID: 20010072.
    Citations: 58     Fields:    Translation:HumansCells
  42. Schapiro JM, Scherer J, Boucher CA, Baxter JD, Tilke C, Perno CF, Maggiolo F, Santoro MM, Hall DB. Improving the prediction of virological response to tipranavir: the development and validation of a tipranavir-weighted mutation score. Antivir Ther. 2010; 15(7):1011-9. PMID: 21041916.
    Citations: 7     Fields:    Translation:HumansCells
  43. Aardema H, Tulleken JE, van den Biggelaar RJ, Wolters BA, de Jager CM, Boucher CA, Riezebos-Brilman A. [Fatal pneumonitis due to oseltamivir-resistant new influenza A(H1N1) in the case of an intensive care patient]. Ned Tijdschr Geneeskd. 2010; 154:A1634. PMID: 20482913.
    Citations: 1     Fields:    Translation:HumansCells
  44. Ciancio BC, Meerhoff TJ, Kramarz P, Bonmarin I, Borgen K, Boucher CA, Buchholz U, Buda S, Dijkstra F, Dudman S, Duwe S, Hauge SH, Hungnes O, Meijer A, Mossong J, Paget WJ, Phin N, van der Sande M, Schweiger B, Nicoll A. Oseltamivir-resistant influenza A(H1N1) viruses detected in Europe during season 2007-8 had epidemiologic and clinical characteristics similar to co-circulating susceptible A(H1N1) viruses. Euro Surveill. 2009 Nov 19; 14(46). PMID: 19941797.
    Citations: 15     Fields:    Translation:HumansCellsPHPublic Health
  45. Vercauteren J, Wensing AM, van de Vijver DA, Albert J, Balotta C, Hamouda O, Kücherer C, Struck D, Schmit JC, Asjö B, Bruckova M, Camacho RJ, Clotet B, Coughlan S, Grossman Z, Horban A, Korn K, Kostrikis L, Nielsen C, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Riva C, Ruiz L, Salminen M, Schuurman R, Sonnerborg A, Stanekova D, Stanojevic M, Vandamme AM, Boucher CA. Transmission of drug-resistant HIV-1 is stabilizing in Europe. J Infect Dis. 2009 Nov 15; 200(10):1503-8. PMID: 19835478.
    Citations: 95     Fields:    Translation:HumansCells
  46. van der Vries E, Jonges M, Herfst S, Maaskant J, Van der Linden A, Guldemeester J, Aron GI, Bestebroer TM, Koopmans M, Meijer A, Fouchier RA, Osterhaus AD, Boucher CA, Schutten M. Evaluation of a rapid molecular algorithm for detection of pandemic influenza A (H1N1) 2009 virus and screening for a key oseltamivir resistance (H275Y) substitution in neuraminidase. J Clin Virol. 2010 Jan; 47(1):34-7. PMID: 19857993.
    Citations: 31     Fields:    Translation:HumansCellsPHPublic Health
  47. Nijhuis M, Wensing AM, Bierman WF, de Jong D, Kagan R, Fun A, Jaspers CA, Schurink KA, van Agtmael MA, Boucher CA. Failure of treatment with first-line lopinavir boosted with ritonavir can be explained by novel resistance pathways with protease mutation 76V. J Infect Dis. 2009 Sep 01; 200(5):698-709. PMID: 19627247.
    Citations: 12     Fields:    Translation:HumansCells
  48. Sloot PM, Coveney PV, Ertaylan G, Müller V, Boucher CA, Bubak M. HIV decision support: from molecule to man. Philos Trans A Math Phys Eng Sci. 2009 Jul 13; 367(1898):2691-703. PMID: 19487205.
    Citations: 8     Fields:    Translation:Humans
  49. Munster VJ, de Wit E, van den Brand JM, Herfst S, Schrauwen EJ, Bestebroer TM, van de Vijver D, Boucher CA, Koopmans M, Rimmelzwaan GF, Kuiken T, Osterhaus AD, Fouchier RA. Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science. 2009 Jul 24; 325(5939):481-3. PMID: 19574348.
    Citations: 314     Fields:    Translation:HumansAnimalsCells
  50. van Asten L, van der Lubben M, van den Wijngaard C, van Pelt W, Verheij R, Jacobi A, Overduin P, Meijer A, Luijt D, Claas E, Hermans M, Melchers W, Rossen J, Schuurman R, Wolffs P, Boucher C, Bouchier C, Schirm J, Kroes L, Leenders S, Galama J, Peeters M, van Loon A, Stobberingh E, Schutten M, Koopmans M. Strengthening the diagnostic capacity to detect Bio Safety Level 3 organisms in unusual respiratory viral outbreaks. J Clin Virol. 2009 Jul; 45(3):185-90. PM