Harvard Catalyst Profiles

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Nagendran Ramalingam, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AG085401 (Nagendran Ramalingam) Aug 15, 2024 - Apr 30, 2026
    NIH
    Distinguishing a-Synuclein S129 Phosphorylation in Health and Lewy Body Dementia
    Role Description: The goal of this project is to refine serine-129 phosphorylated a-synuclein as a biomarker.
    Role: Principal Investigator
  2. RF1NS133979 (Ulf Dettmer and Nagendran Ramalingam) Aug 1, 2023 - Jul 31, 2028
    NIH
    How serine-129 phosphorylation status affects the spreading of a-synuclein pathology in vivo: a study in knock-in animals.
    Role Description: The goal of this project is to explain the contribution of a-synuclein serine-129 phosphorylation in synucleinopathies mechanistically.
    Role: Principal Investigator
  3. RF1AG079569 (Jasmeer Chatwal) Aug 12, 2022 - Jul 31, 2027
    NIH
    Leveraging Heterogeneity in Autosomal Dominant AD to Elucidate Pathophysiology and Improve AD Biomarkers.
    Role Description: The goal of this project is to stratify AD pathophysiology using plasma and CSF biomarkers.
    Role: Co-Investigator
  4. RF1NS122880 (Ulf Dettmer and Nagendran Ramalingam) Jul 1, 2022 - Jun 30, 2027
    NIH
    Polo-like-kinase-2-dependent a-synuclein serine-129 phosphorylation: a physiological role during synaptic activity.
    Role Description: The goal of this project is to understand the physiological role of a-synuclein serine-129 phosphorylation at active synapses during neuronal activity.
    Role: Principal Investigator
  5. PIN award (Nagendran Ramalingam) Jan 1, 2019 - Jan 31, 2022
    Program in Neuroscience, Brigham & Women's Hospital
    The role of alpha-synuclein tetramerization at the synapse.
    Role Description: The goal of this project was to characterize the structure-function relationship of a-synuclein during neuronal activity.
    Role: Principal Inverstigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.