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Angeliki Vgontzas, M.D.

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National Institutes of Health - Intramural Research Training Award, Bethesda, MD2007Migraine; Genetic Epidemiology
Penn State College of Medicine, Hershey, PAMD05/2013
Albert Einstein College of Medicine - Montefiore Medical Center, Bronx, NY06/2017Neurology Residency
Harvard Medical School - Graham Headache Center, Brigham and Women's Hospital, Boston, MA06/2018Clinical Headache Fellowship

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Vgontzas A, Loder E. Addressing inequities in headache care by embedding services in a community health center in Boston, MA. Headache. 2022 Nov; 62(10):1416-1418. PMID: 36322009.
    Citations:    Fields:    Translation:Humans
  2. Yoo A, Vgontzas A, Chung J, Mostofsky E, Li W, Rueschman M, Buysse D, Mittleman M, Bertisch S. The association between multidimensional sleep health and migraine burden among patients with episodic migraine. J Clin Sleep Med. 2022 Oct 21. PMID: 36263856.
    Citations:    Fields:    
  3. Vgontzas A, Mostofsky E, Hagan K, Rueschman M, Mittleman MA, Bertisch SM. Napping behavior in adults with episodic migraine: a six-week prospective cohort study. Sleep. 2022 03 14; 45(3). PMID: 34791487; PMCID: PMC8919195.
    Citations:    Fields:    Translation:Humans
  4. Loder EW, Vgontzas A. Equal Pay for Women Neurologists: Show Us the Money! Neurology. 2022 03 01; 98(9):347-348. PMID: 35064026.
    Citations:    Fields:    Translation:Humans
  5. Gheihman G, Vgontzas A, Paulson J, Pilgrim D, Batchelor T, O'Neal MA, Doughty CT. Integrating Advanced Practice Providers in an Academic Department of Neurology. Neurol Clin Pract. 2021 Dec; 11(6):462-471. PMID: 34992954; PMCID: PMC8723928.
  6. Vgontzas A, Li W, Mostofsky E, Mittleman MA, Bertisch SM. Baseline sleep quality, stress, and depressive symptoms, and subsequent headache occurrence in a six-week prospective cohort study of patients with episodic migraine. Headache. 2021 May; 61(5):727-733. PMID: 33749835.
    Citations: 2     Fields:    Translation:Humans
  7. Hagan KK, Li W, Mostofsky E, Bertisch SM, Vgontzas A, Buettner C, Mittleman MA. Prospective cohort study of routine exercise and headache outcomes among adults with episodic migraine. Headache. 2021 Mar; 61(3):493-499. PMID: 33349935; PMCID: PMC7987744.
    Citations:    Fields:    Translation:Humans
  8. Vgontzas A, Li W, Mostofsky E, Mittleman MA, Bertisch SM. The Sleep - Migraine Enigma: A Comment. Headache. 2020 11; 60(10):2610. PMID: 33249586.
    Citations:    Fields:    Translation:Humans
  9. Daghlas I, Vgontzas A, Guo Y, Chasman DI, Saxena R. Habitual sleep disturbances and migraine: a Mendelian randomization study. Ann Clin Transl Neurol. 2020 12; 7(12):2370-2380. PMID: 33125193; PMCID: PMC7732254.
    Citations: 2     Fields:    Translation:Humans
  10. Vgontzas A, Li W, Mostofsky E, Rueschman M, Mittleman MA, Bertisch SM. Associations between migraine attacks and nightly sleep characteristics among adults with episodic migraine: a prospective cohort study. Sleep. 2020 07 13; 43(7). PMID: 31930318.
    Citations: 2     Fields:    Translation:Humans
  11. Vgontzas A, Renthal W. Predicting erenumab adverse events with single-cell genomics. Lancet. 2020 07 11; 396(10244):95-96. PMID: 32653068.
    Citations: 2     Fields:    Translation:HumansAnimals
  12. Li W, Bertisch SM, Mostofsky E, Vgontzas A, Mittleman MA. Associations of daily weather and ambient air pollution with objectively assessed sleep duration and fragmentation: a prospective cohort study. Sleep Med. 2020 11; 75:181-187. PMID: 32858358.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  13. Mostofsky E, Bertisch SM, Vgontzas A, Buettner C, Li W, Rueschman M, Mittleman MA. Prospective cohort study of daily alcoholic beverage intake as a potential trigger of headaches among adults with episodic migraine. Ann Med. 2020 11; 52(7):386-392. PMID: 32306754.
    Citations: 3     Fields:    Translation:Humans
  14. Vgontzas A, Renthal W. Migraine-associated gene expression in cell types of the central and peripheral nervous system. Cephalalgia. 2020 04; 40(5):517-523. PMID: 31660761.
    Citations: 3     Fields:    Translation:HumansCells
  15. VanderPluym JH, Hamilton K, Hindiyeh NA, Robbins MS, Starling AJ, Vargas BB, Gibbons SK, Vgontzas A. Online Migraine Education and Support for Patients: Perspectives from the American Headache Society Emerging Leaders Program. Headache. 2019 10; 59(9):1656-1658. PMID: 31508808.
    Citations:    Fields:    Translation:Humans
  16. Vgontzas A, Rizzoli PB. Nonmigraine Headache and Facial Pain. Med Clin North Am. 2019 Mar; 103(2):235-250. PMID: 30704679.
    Citations:    Fields:    Translation:Humans
  17. Vgontzas A, Burch R. Episodic Migraine With and Without Aura: Key Differences and Implications for Pathophysiology, Management, and Assessing Risks. Curr Pain Headache Rep. 2018 Oct 05; 22(12):78. PMID: 30291554.
    Citations: 15     Fields:    Translation:Humans
  18. Vgontzas A, Pavlovic JM. Sleep Disorders and Migraine: Review of Literature and Potential Pathophysiology Mechanisms. Headache. 2018 Jul; 58(7):1030-1039. PMID: 30091160; PMCID: PMC6527324.
    Citations: 38     Fields:    Translation:Humans
  19. Vgontzas A, Renthal W. Introduction to Neurogenetics. Am J Med. 2019 02; 132(2):142-152. PMID: 30098310.
    Citations: 2     Fields:    Translation:Humans
  20. Vgontzas A, Papke DJ, Bernstein CA. Giant Cell Arteritis. Headache. 2018 Jun; 58(6):883-884. PMID: 29924413.
    Citations:    Fields:    Translation:Humans
  21. Vgontzas A, Robbins MS. A Hospital Based Retrospective Study of Acute Postpartum Headache. Headache. 2018 Jun; 58(6):845-851. PMID: 29446070.
    Citations: 3     Fields:    Translation:Humans
  22. Vgontzas A, Prasad S, Burch RC. Papilledema in Idiopathic Intracranial Hypertension. Headache. 2018 Apr; 58(4):579-580. PMID: 29399792.
    Citations:    Fields:    Translation:Humans
  23. LaGrotte C, Fernandez-Mendoza J, Calhoun SL, Liao D, Bixler EO, Vgontzas AN. The relative association of obstructive sleep apnea, obesity and excessive daytime sleepiness with incident depression: a longitudinal, population-based study. Int J Obes (Lond). 2016 09; 40(9):1397-404. PMID: 27143032.
    Citations: 23     Fields:    Translation:Humans
  24. Vgontzas A, Charleston L, Robbins MS. Headache and Facial Pain in Sickle Cell Disease. Curr Pain Headache Rep. 2016 Mar; 20(3):20. PMID: 26879878.
    Citations: 4     Fields:    Translation:Humans
  25. Tekin I, Vgontzas A, Lewis MM, Kothari S, Kong L, Lu Y, Vrana KE, Huang X. Previous Injury and Chronic Pain are Associated with Side of Onset in Parkinson's Disease. J Neurol Neurobiol. 2015 Jul; 1(3). PMID: 26937489; PMCID: PMC4771383.
  26. Fernandez-Mendoza J, Vgontzas AN, Calhoun SL, Vgontzas A, Tsaoussoglou M, Gaines J, Liao D, Chrousos GP, Bixler EO. Insomnia symptoms, objective sleep duration and hypothalamic-pituitary-adrenal activity in children. Eur J Clin Invest. 2014 May; 44(5):493-500. PMID: 24635035.
    Citations: 25     Fields:    Translation:Humans
  27. Pejovic S, Vgontzas AN, Basta M, Tsaoussoglou M, Zoumakis E, Vgontzas A, Bixler EO, Chrousos GP. Leptin and hunger levels in young healthy adults after one night of sleep loss. J Sleep Res. 2010 Dec; 19(4):552-8. PMID: 20545838.
    Citations: 52     Fields:    Translation:Humans
  28. Vgontzas A, Cui L, Merikangas KR. Are sleep difficulties associated with migraine attributable to anxiety and depression? Headache. 2008 Nov-Dec; 48(10):1451-9. PMID: 18624714.
    Citations: 30     Fields:    Translation:Humans
  29. Vgontzas AN, Zoumakis E, Lin HM, Bixler EO, Trakada G, Chrousos GP. Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist. J Clin Endocrinol Metab. 2004 Sep; 89(9):4409-13. PMID: 15356039.
    Citations: 111     Fields:    Translation:HumansCTClinical Trials
  30. Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Follett H, Kales A, Chrousos GP. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab. 2004 May; 89(5):2119-26. PMID: 15126529.
    Citations: 329     Fields:    Translation:Humans
  31. Vgontzas AN, Bixler EO, Chrousos GP. Metabolic disturbances in obesity versus sleep apnoea: the importance of visceral obesity and insulin resistance. J Intern Med. 2003 Jul; 254(1):32-44. PMID: 12823641.
    Citations: 71     Fields:    Translation:Humans
  32. Vgontzas AN, Zoumakis M, Papanicolaou DA, Bixler EO, Prolo P, Lin HM, Vela-Bueno A, Kales A, Chrousos GP. Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime. Metabolism. 2002 Jul; 51(7):887-92. PMID: 12077736.
    Citations: 91     Fields:    Translation:HumansCTClinical Trials
  33. Bixler EO, Vgontzas AN, Lin HM, Vela-Bueno A, Kales A. Insomnia in central Pennsylvania. J Psychosom Res. 2002 Jul; 53(1):589-92. PMID: 12127176.
    Citations: 55     Fields:    Translation:Humans
  34. Vgontzas AN, Bixler EO, Lin HM, Prolo P, Mastorakos G, Vela-Bueno A, Kales A, Chrousos GP. Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications. J Clin Endocrinol Metab. 2001 Aug; 86(8):3787-94. PMID: 11502812.
    Citations: 203     Fields:    Translation:Humans
  35. Vgontzas AN, Bixler EO, Wittman AM, Zachman K, Lin HM, Vela-Bueno A, Kales A, Chrousos GP. Middle-aged men show higher sensitivity of sleep to the arousing effects of corticotropin-releasing hormone than young men: clinical implications. J Clin Endocrinol Metab. 2001 Apr; 86(4):1489-95. PMID: 11297573.
    Citations: 17     Fields:    Translation:HumansAnimals
  36. Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Rein J, Vela-Bueno A, Kales A. Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med. 2001 Mar; 163(3 Pt 1):608-13. PMID: 11254512.
    Citations: 396     Fields:    Translation:Humans
  37. Vgontzas AN, Legro RS, Bixler EO, Grayev A, Kales A, Chrousos GP. Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: role of insulin resistance. J Clin Endocrinol Metab. 2001 Feb; 86(2):517-20. PMID: 11158002.
    Citations: 80     Fields:    Translation:Humans
  38. Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Leiby BE, Vela-Bueno A, Kales A. Association of hypertension and sleep-disordered breathing. Arch Intern Med. 2000 Aug 14-28; 160(15):2289-95. PMID: 10927725.
    Citations: 115     Fields:    Translation:Humans
  39. Vgontzas AN, Bixler EO, Papanicolaou DA, Chrousos GP. Chronic systemic inflammation in overweight and obese adults. JAMA. 2000 May 03; 283(17):2235; author reply 2236. PMID: 10807374.
    Citations: 14     Fields:    Translation:Humans
  40. Vgontzas AN, Papanicolaou DA, Bixler EO, Hopper K, Lotsikas A, Lin HM, Kales A, Chrousos GP. Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia. J Clin Endocrinol Metab. 2000 Mar; 85(3):1151-8. PMID: 10720054.
    Citations: 312     Fields:    Translation:HumansCTClinical Trials
  41. Vgontzas AN, Bixler EO, Kales A, Criley C, Vela-Bueno A. Differences in nocturnal and daytime sleep between primary and psychiatric hypersomnia: diagnostic and treatment implications. Psychosom Med. 2000 Mar-Apr; 62(2):220-6. PMID: 10772401.
    Citations: 22     Fields:    Translation:Humans
  42. Vgontzas AN, Mastorakos G, Bixler EO, Kales A, Gold PW, Chrousos GP. Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications. Clin Endocrinol (Oxf). 1999 Aug; 51(2):205-15. PMID: 10468992.
    Citations: 48     Fields:    Translation:HumansCTClinical Trials
  43. Vgontzas AN, Papanicolaou DA, Bixler EO, Lotsikas A, Zachman K, Kales A, Prolo P, Wong ML, Licinio J, Gold PW, Hermida RC, Mastorakos G, Chrousos GP. Circadian interleukin-6 secretion and quantity and depth of sleep. J Clin Endocrinol Metab. 1999 Aug; 84(8):2603-7. PMID: 10443646.
    Citations: 145     Fields:    Translation:Humans
  44. Vgontzas AN, Kales A. Sleep and its disorders. Annu Rev Med. 1999; 50:387-400. PMID: 10073285.
    Citations: 36     Fields:    Translation:Humans
  45. Vgontzas AN, Tsigos C, Bixler EO, Stratakis CA, Zachman K, Kales A, Vela-Bueno A, Chrousos GP. Chronic insomnia and activity of the stress system: a preliminary study. J Psychosom Res. 1998 Jul; 45(1):21-31. PMID: 9720852.
    Citations: 94     Fields:    Translation:Humans
  46. Vgontzas AN, Bixler EO, Tan TL, Kantner D, Martin LF, Kales A. Obesity without sleep apnea is associated with daytime sleepiness. Arch Intern Med. 1998 Jun 22; 158(12):1333-7. PMID: 9645828.
    Citations: 75     Fields:    Translation:Humans
  47. Bixler EO, Vgontzas AN, Ten Have T, Tyson K, Kales A. Effects of age on sleep apnea in men: I. Prevalence and severity. Am J Respir Crit Care Med. 1998 Jan; 157(1):144-8. PMID: 9445292.
    Citations: 330     Fields:    Translation:Humans
  48. Nowell PD, Buysse DJ, Reynolds CF, Hauri PJ, Roth T, Stepanski EJ, Thorpy MJ, Bixler E, Kales A, Manfredi RL, Vgontzas AN, Stapf DM, Houck PR, Kupfer DJ. Clinical factors contributing to the differential diagnosis of primary insomnia and insomnia related to mental disorders. Am J Psychiatry. 1997 Oct; 154(10):1412-6. PMID: 9326824.
    Citations: 9     Fields:    Translation:Humans
  49. Vgontzas AN, Bixler EO, Papanicolaou DA, Kales A, Stratakis CA, Vela-Bueno A, Gold PW, Chrousos GP. Rapid eye movement sleep correlates with the overall activities of the hypothalamic-pituitary-adrenal axis and sympathetic system in healthy humans. J Clin Endocrinol Metab. 1997 Oct; 82(10):3278-80. PMID: 9329353.
    Citations: 8     Fields:    Translation:Humans
  50. Vgontzas AN, Papanicolaou DA, Bixler EO, Kales A, Tyson K, Chrousos GP. Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity. J Clin Endocrinol Metab. 1997 May; 82(5):1313-6. PMID: 9141509.
    Citations: 244     Fields:    Translation:Humans
  51. Vgontzas AN, Bixler EO, Kales A, Centurione A, Rogan PK, Mascari M, Vela-Bueno A. Daytime sleepiness and REM abnormalities in Prader-Willi syndrome: evidence of generalized hypoarousal. Int J Neurosci. 1996 Nov; 87(3-4):127-39. PMID: 9003974.
    Citations: 13     Fields:    Translation:Humans
  52. Vgontzas AN, Kales A, Seip J, Mascari MJ, Bixler EO, Myers DC, Vela-Bueno AV, Rogan PK. Relationship of sleep abnormalities to patient genotypes in Prader-Willi syndrome. Am J Med Genet. 1996 Sep 20; 67(5):478-82. PMID: 8886165.
    Citations: 14     Fields:    Translation:HumansCells
  53. Vgontzas AN, Sollenberger SE, Kales A, Bixler EO, Vela-Bueno A. Narcolepsy-cataplexy and loss of sphincter control. Postgrad Med J. 1996 Aug; 72(850):493-4. PMID: 8796217.
    Citations:    Fields:    Translation:Humans
  54. Kales A, Vgontzas AN, Bixler EO. A reassessment of triazolam. Int J Risk Saf Med. 1996; 9(1):7-27. PMID: 23512020.
    Citations:    Fields:    
  55. Vgontzas AN, Kales A, Bixler EO. Benzodiazepine side effects: role of pharmacokinetics and pharmacodynamics. Pharmacology. 1995 Oct; 51(4):205-23. PMID: 8577815.
    Citations: 17     Fields:    Translation:Humans
  56. Vgontzas AN, Bixler EO, Kales A, Vela-Bueno A. Prader-Willi syndrome: effects of weight loss on sleep-disordered breathing, daytime sleepiness and REM sleep disturbance. Acta Paediatr. 1995 Jul; 84(7):813-4. PMID: 7549304.
    Citations: 6     Fields:    Translation:Humans
  57. Vgontzas AN, Kales A, Bixler EO, Manfredi RL, Vela-Bueno A. Usefulness of polysomnographic studies in the differential diagnosis of insomnia. Int J Neurosci. 1995 May; 82(1-2):47-60. PMID: 7591515.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  58. Vgontzas AN, Friedman TC, Chrousos GP, Bixler EO, Vela-Bueno A, Kales A. Delta sleep-inducing peptide in normal humans and in patients with sleep apnea and narcolepsy. Peptides. 1995; 16(6):1153-6. PMID: 8532601.
    Citations:    Fields:    Translation:HumansCells
  59. Buysse DJ, Reynolds CF, Hauri PJ, Roth T, Stepanski EJ, Thorpy MJ, Bixler EO, Kales A, Manfredi RL, Vgontzas AN, et al. Diagnostic concordance for DSM-IV sleep disorders: a report from the APA/NIMH DSM-IV field trial. Am J Psychiatry. 1994 Sep; 151(9):1351-60. PMID: 8067492.
    Citations: 21     Fields:    Translation:Humans
  60. Vgontzas AN, Tan TL, Bixler EO, Martin LF, Shubert D, Kales A. Sleep apnea and sleep disruption in obese patients. Arch Intern Med. 1994 Aug 08; 154(15):1705-11. PMID: 8042887.
    Citations: 113     Fields:    Translation:Humans
  61. Vgontzas AN, Bixler EO, Kales A, Manfredi RL, Tyson K. Validity and clinical utility of sleep laboratory criteria for insomnia. Int J Neurosci. 1994 Jul; 77(1-2):11-21. PMID: 7989156.
    Citations: 14     Fields:    Translation:Humans
  62. Vgontzas AN, Kales A, Bixler EO, Myers DC. Temazepam 7.5 mg: effects on sleep in elderly insomniacs. Eur J Clin Pharmacol. 1994; 46(3):209-13. PMID: 8070501.
    Citations: 3     Fields:    Translation:Humans
  63. Kales A, Bixler EO, Vgontzas AN. Triazolam. The evidence against is extensive and consistent. BMJ. 1993 Sep 04; 307(6904):626. PMID: 8401035; PMCID: PMC1678896.
    Citations:    Fields:    Translation:HumansPHPublic Health
  64. Vgontzas AN, Kales JD, Ballard JO, Vela-Bueno A, Tan TL. Porphyria and panic disorder with agoraphobia. Psychosomatics. 1993 Sep-Oct; 34(5):440-3. PMID: 8140193.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.