Harvard Catalyst Profiles

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James Donald Byrne, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Byrne JD, Wentworth AJ, Chai PR, Huang HW, Babaee S, Li C, Becker SL, Tov C, Min S, Traverso G. Injection Molded Autoclavable, Scalable, Conformable (iMASC) system for aerosol-based protection: a prospective single-arm feasibility study. BMJ Open. 2020 07 07; 10(7):e039120. PMID: 32641368.
  2. Sadtler K, Collins J, Byrne JD, Langer R. Parallel evolution of polymer chemistry and immunology: Integrating mechanistic biology with materials design. Adv Drug Deliv Rev. 2020 Jun 23. PMID: 32589903.
  3. Byrne JD, Botticello T, Niemierko A, Shih HA, Loeffler JS, Oh KS. Post-operative radiation therapy to the surgical cavity with standard fractionation in patients with brain metastases. Sci Rep. 2020 Apr 14; 10(1):6331. PMID: 32286375.
  4. Byrne JD, Yeh JJ, DeSimone JM. Use of iontophoresis for the treatment of cancer. J Control Release. 2018 08 28; 284:144-151. PMID: 29908892.
    Citations:    Fields:    
  5. Byrne JD, Jajja MRN, O'Neill AT, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer. Cancer Chemother Pharmacol. 2018 06; 81(6):991-998. PMID: 29603014.
    Citations:    Fields:    
  6. Bowerman CJ, Byrne JD, Chu KS, Schorzman AN, Keeler AW, Sherwood CA, Perry JL, Luft JC, Darr DB, Deal AM, Napier ME, Zamboni WC, Sharpless NE, Perou CM, DeSimone JM. Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer. Nano Lett. 2017 01 11; 17(1):242-248. PMID: 27966988.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  7. Byrne JD, Jajja MR, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2200-5. PMID: 26858448.
    Citations: 1     Fields:    Translation:HumansAnimals
  8. Roberts RA, Eitas TK, Byrne JD, Johnson BM, Short PJ, McKinnon KP, Reisdorf S, Luft JC, DeSimone JM, Ting JP. Towards programming immune tolerance through geometric manipulation of phosphatidylserine. Biomaterials. 2015 Dec; 72:1-10. PMID: 26325217.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  9. Byrne JD, Jajja MR, O'Neill AT, Bickford LR, Keeler AW, Hyder N, Wagner K, Deal A, Little RE, Moffitt RA, Stack C, Nelson M, Brooks CR, Lee W, Luft JC, Napier ME, Darr D, Anders CK, Stack R, Tepper JE, Wang AZ, Zamboni WC, Yeh JJ, DeSimone JM. Local iontophoretic administration of cytotoxic therapies to solid tumors. Sci Transl Med. 2015 Feb 04; 7(273):273ra14. PMID: 25653220.
    Citations: 5     Fields:    Translation:HumansAnimals
  10. Xu J, Wong DH, Byrne JD, Chen K, Bowerman C, DeSimone JM. Future of the particle replication in nonwetting templates (PRINT) technology. Angew Chem Int Ed Engl. 2013 Jun 24; 52(26):6580-9. PMID: 23670869.
    Citations: 13     Fields:    Translation:Humans
  11. Dunn SS, Byrne JD, Perry JL, Chen K, Desimone JM. Generating Better Medicines for Cancer. ACS Macro Lett. 2013 Apr 24; 2(5):393-397. PMID: 23772351.
  12. Wang Y, Byrne JD, Napier ME, DeSimone JM. Engineering nanomedicines using stimuli-responsive biomaterials. Adv Drug Deliv Rev. 2012 Aug; 64(11):1021-30. PMID: 22266128.
    Citations: 13     Fields:    
  13. Wang J, Byrne JD, Napier ME, DeSimone JM. More effective nanomedicines through particle design. Small. 2011 Jul 18; 7(14):1919-31. PMID: 21695781.
    Citations: 64     Fields:    Translation:Cells
  14. Parrott MC, Luft JC, Byrne JD, Fain JH, Napier ME, Desimone JM. Tunable bifunctional silyl ether cross-linkers for the design of acid-sensitive biomaterials. J Am Chem Soc. 2010 Dec 22; 132(50):17928-32. PMID: 21105720.
    Citations: 20     Fields:    Translation:Cells
  15. Betancourt T, Byrne JD, Sunaryo N, Crowder SW, Kadapakkam M, Patel S, Casciato S, Brannon-Peppas L. PEGylation strategies for active targeting of PLA/PLGA nanoparticles. J Biomed Mater Res A. 2009 Oct; 91(1):263-76. PMID: 18980197.
    Citations: 21     Fields:    Translation:Animals
  16. Byrne JD, Betancourt T, Brannon-Peppas L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev. 2008 Dec 14; 60(15):1615-26. PMID: 18840489.
    Citations: 180     Fields:    Translation:HumansAnimals
  17. Fonner JM, Forciniti L, Nguyen H, Byrne JD, Kou YF, Syeda-Nawaz J, Schmidt CE. Biocompatibility implications of polypyrrole synthesis techniques. Biomed Mater. 2008 Sep; 3(3):034124. PMID: 18765899.
    Citations: 16     Fields:    
  18. Byrne JD, Baugh JA. The significance of nanoparticles in particle-induced pulmonary fibrosis. Mcgill J Med. 2008 Jan; 11(1):43-50. PMID: 18523535.
    Citations: 11     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.