Harvard Catalyst Profiles

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Sepideh Afshar, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yuan G, Dhaynaut M, Guehl NJ, Neelamegam R, Moon SH, Qu X, Poutiainen P, Afshar S, Fakhri GE, Normandin MD, Brownell AL. PET imaging studies to investigate functional expression of mGluR2 using [11C]mG2P001. J Cereb Blood Flow Metab. 2023 02; 43(2):296-308. PMID: 36172629; PMCID: PMC9903221.
    Citations:    Fields:    Translation:Animals
  2. Yuan G, Dhaynaut M, Guehl NJ, Afshar S, Huynh D, Moon SH, Iyengar SM, Jain MK, Pickett JE, Kang HJ, Ondrechen MJ, El Fakhri G, Normandin MD, Brownell AL. Design, Synthesis, and Characterization of [18F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2. J Med Chem. 2022 07 28; 65(14):9939-9954. PMID: 35802702; PMCID: PMC9434700.
    Citations:    Fields:    Translation:Animals
  3. Bai P, Liu Y, Xu Y, Striar R, Yuan G, Afshar S, Langan AG, Rattray AK, Wang C. Synthesis and characterization of a new Positron emission tomography probe for orexin 2 receptors neuroimaging. Bioorg Chem. 2022 06; 123:105779. PMID: 35397430; PMCID: PMC9050936.
    Citations:    Fields:    Translation:Animals
  4. Xu Y, Liu Y, Striar R, Langan A, Kate Rattray A, Afshar S, Wang C. Preliminary studies of an imidazole-based alcohol derivative for imaging of Heme oxygenase 1. Bioorg Med Chem Lett. 2022 05 15; 64:128674. PMID: 35292342.
    Citations:    Fields:    Translation:Animals
  5. Yuan G, Dhaynaut M, Lan Y, Guehl NJ, Huynh D, Iyengar SM, Afshar S, Jain MK, Pickett JE, Kang HJ, Wang H, Moon SH, Ondrechen MJ, Wang C, Shoup TM, El Fakhri G, Normandin MD, Brownell AL. Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2. J Med Chem. 2022 02 10; 65(3):2593-2609. PMID: 35089713; PMCID: PMC9434702.
    Citations:    Fields:    Translation:Animals
  6. Afshar S, Lule S, Yuan G, Qu X, Pan C, Whalen M, Brownell AL, Mody M. Longitudinal PET studies of mGluR5 in FXS using an FMR1 knockout mouse model. Transl Neurosci. 2022 Jan 01; 13(1):80-92. PMID: 35582646; PMCID: PMC9055256.
    Citations:    
  7. Lan Y, Bai P, Liu Y, Afshar S, Striar R, Rattray AK, Meyer TN, Langan AG, Posner AM, Shen S, Tanzi RE, Zhang C, Wang C. Visualization of Receptor-Interacting Protein Kinase 1 (RIPK1) by Brain Imaging with Positron Emission Tomography. J Med Chem. 2021 10 28; 64(20):15420-15428. PMID: 34652135; PMCID: PMC8858444.
    Citations: 1     Fields:    Translation:AnimalsCells
  8. Bai P, Lan Y, Patnaik D, Wang H, Liu Y, Chen Z, Yuan G, Afshar S, Striar R, Zagaroli JS, Tocci DR, Langan AG, Haggarty SJ, Wang C. Design, Synthesis, and Evaluation of Thienodiazepine Derivatives as Positron Emission Tomography Imaging Probes for Bromodomain and Extra-Terminal Domain Family Proteins. J Med Chem. 2021 10 14; 64(19):14745-14756. PMID: 34549949.
    Citations:    Fields:    Translation:AnimalsCells
  9. Bai P, Lan Y, Wang H, Liu Y, Striar R, Yuan G, Afshar S, Zagaroli JS, Tocci DR, Langan AG, Wang C. Synthesis and Characterization of a Positron Emission Tomography Imaging Probe Selectively Targeting the Second Bromodomain of Bromodomain Protein BRD4. Bioconjug Chem. 2021 08 18; 32(8):1711-1718. PMID: 34139120.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Yuan G, Guehl NJ, Zheng B, Qu X, Moon SH, Dhaynaut M, Shoup TM, Afshar S, Kang HJ, Zhang Z, El Fakhri G, Normandin MD, Brownell AL. Synthesis and Characterization of [18F]JNJ-46356479 as the First 18F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2. Mol Imaging Biol. 2021 08; 23(4):527-536. PMID: 33559035; PMCID: PMC8277681.
    Citations: 1     Fields:    Translation:Animals
  11. Yuan G, Qu X, Zheng B, Neelamegam R, Afshar S, Iyengar S, Pan C, Wang J, Kang HJ, Ondrechen MJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Design, Synthesis, and Characterization of Benzimidazole Derivatives as Positron Emission Tomography Imaging Ligands for Metabotropic Glutamate Receptor 2. J Med Chem. 2020 10 22; 63(20):12060-12072. PMID: 32981322.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  12. Wang J, Qu X, Shoup TM, Yuan G, Afshar S, Pan C, Zhu A, Choi JK, Kang HJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d2)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain. J Med Chem. 2020 03 26; 63(6):3381-3389. PMID: 32081008.
    Citations:    Fields:    Translation:AnimalsCells
  13. Wertheimer CM, Elhardt C, Kaminsky SM, Pham L, Pei Q, Mendes B, Afshar S, Kochevar IE. Enhancing Rose Bengal-Photosensitized Protein Crosslinking in the Cornea. Invest Ophthalmol Vis Sci. 2019 05 01; 60(6):1845-1852. PMID: 31042790.
    Citations: 11     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.