Harvard Catalyst Profiles

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Viral Shailesh Shah, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F30HL123239 (SHAH, VIRAL SHAILESH) May 1, 2014 - Apr 30, 2018
    Mechanisms Controlling Airway Surface Liquid pH
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kadar A, Shah VS, Mendoza DP, Lai PS, Aghajan Y, Piazza G, Camargo EC, Viswanathan K. Case 39-2021: A 26-Year-Old Woman with Respiratory Failure and Altered Mental Status. N Engl J Med. 2021 Dec 23; 385(26):2464-2474. PMID: 34936743.
    Citations: 1     Fields:    Translation:Humans
  2. Zureigat H, Frank R, Shah VS, Makarenko V, Hucker W, Ho JE, Wood MJ, Osborne MT. Cardiac Sarcoidosis Initially Diagnosed as Spontaneous Coronary Artery Dissection. JACC Case Rep. 2021 Nov 03; 3(15):1656-1660. PMID: 34766013.
  3. Matasic DS, Holland N, Gautam M, Gibbons DD, Kusama N, Harding AMS, Shah VS, Snyder PM, Benson CJ. Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel. Front Physiol. 2021; 12:750696. PMID: 34721074; PMCID: PMC8555766.
  4. Shah VS, Chivukula RR, Lin B, Waghray A, Rajagopal J. Cystic Fibrosis and the Cells of the Airway Epithelium: What Are Ionocytes and What Do They Do? Annu Rev Pathol. 2022 01 24; 17:23-46. PMID: 34437820.
    Citations:    Fields:    Translation:HumansAnimalsCells
  5. Shah V, Jacob DJ, Thackray CP, Wang X, Sunderland EM, Dibble TS, Saiz-Lopez A, Cernušák I, Kellö V, Castro PJ, Wu R, Wang C. Improved Mechanistic Model of the Atmospheric Redox Chemistry of Mercury. Environ Sci Technol. 2021 11 02; 55(21):14445-14456. PMID: 34724789.
    Citations: 2     Fields:    Translation:CellsPHPublic Health
  6. Qu Z, Jacob DJ, Silvern RF, Shah V, Campbell PC, Valin LC, Murray LT. US COVID-19 Shutdown Demonstrates Importance of Background NO2 in Inferring NOx Emissions From Satellite NO2 Observations. Geophys Res Lett. 2021 May 28; 48(10):e2021GL092783. PMID: 34149109.
    Citations: 4     
  7. Cooney AL, Thornell IM, Singh BK, Shah VS, Stoltz DA, McCray PB, Zabner J, Sinn PL. A Novel AAV-mediated Gene Delivery System Corrects CFTR Function in Pigs. Am J Respir Cell Mol Biol. 2019 12; 61(6):747-754. PMID: 31184507.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  8. Muraglia KA, Chorghade RS, Kim BR, Tang XX, Shah VS, Grillo AS, Daniels PN, Cioffi AG, Karp PH, Zhu L, Welsh MJ, Burke MD. Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia. Nature. 2019 03; 567(7748):405-408. PMID: 30867598.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  9. Cooney AL, Abou Alaiwa MH, Shah VS, Bouzek DC, Stroik MR, Powers LS, Gansemer ND, Meyerholz DK, Welsh MJ, Stoltz DA, Sinn PL, McCray PB. Lentiviral-mediated phenotypic correction of cystic fibrosis pigs. JCI Insight. 2016 09 08; 1(14). PMID: 27656681; PMCID: PMC5027966.
    Citations: 40     Fields:    Translation:AnimalsCells
  10. Steines B, Dickey DD, Bergen J, Excoffon KJ, Weinstein JR, Li X, Yan Z, Abou Alaiwa MH, Shah VS, Bouzek DC, Powers LS, Gansemer ND, Ostedgaard LS, Engelhardt JF, Stoltz DA, Welsh MJ, Sinn PL, Schaffer DV, Zabner J. CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes. JCI Insight. 2016 09 08; 1(14):e88728. PMID: 27699238.
    Citations: 41     Fields:    Translation:AnimalsCells
  11. Shah VS, Ernst S, Tang XX, Karp PH, Parker CP, Ostedgaard LS, Welsh MJ. Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5382-7. PMID: 27114540.
    Citations: 29     Fields:    Translation:Animals
  12. Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ. Airway acidification initiates host defense abnormalities in cystic fibrosis mice. Science. 2016 Jan 29; 351(6272):503-7. PMID: 26823428.
    Citations: 142     Fields:    Translation:HumansAnimals
  13. Dong Q, Ernst SE, Ostedgaard LS, Shah VS, Ver Heul AR, Welsh MJ, Randak CO. Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia. J Biol Chem. 2015 May 29; 290(22):14140-53. PMID: 25887396.
    Citations: 3     Fields:    Translation:HumansCells
  14. Shah VS, Jung NL, Lee DK, Nepple KG. Does Routine Pathology Analysis of Adult Circumcision Tissue Identify Penile Cancer? Urology. 2015 Jun; 85(6):1431-1434. PMID: 25872693.
    Citations: 2     Fields:    Translation:Humans
  15. Chang EH, Tang XX, Shah VS, Launspach JL, Ernst SE, Hilkin B, Karp PH, Abou Alaiwa MH, Graham SM, Hornick DB, Welsh MJ, Stoltz DA, Zabner J. Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor. Int Forum Allergy Rhinol. 2015 Feb; 5(2):178-81. PMID: 25363320.
    Citations: 20     Fields:    Translation:HumansCells
  16. Shah VS, Nepple KG, Lee DK. Routine pathology evaluation of hydrocele and spermatocele specimens is associated with significant costs and no identifiable benefit. J Urol. 2014 Oct; 192(4):1179-82. PMID: 24768992.
    Citations: 4     Fields:    Translation:Humans
  17. Mark MD, Maejima T, Kuckelsberg D, Yoo JW, Hyde RA, Shah V, Gutierrez D, Moreno RL, Kruse W, Noebels JL, Herlitze S. Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations. J Neurosci. 2011 Mar 16; 31(11):4311-26. PMID: 21411672.
    Citations: 52     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.