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Vikram Khedgikar, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ahmad N, Kushwaha P, Karvande A, Tripathi AK, Kothari P, Adhikary S, Khedgikar V, Mishra VK, Trivedi R. MicroRNA-672-5p Identified during Weaning Reverses Osteopenia and Sarcopenia in Ovariectomized Mice. Mol Ther Nucleic Acids. 2019 Mar 01; 14:536-549. PMID: 30769134.
    Citations:    
  2. Karvande A, Kushwaha P, Ahmad N, Adhikary S, Kothari P, Tripathi AK, Khedgikar V, Trivedi R. Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation. Bone. 2018 12; 117:98-115. PMID: 30218791.
    Citations:    Fields:    
  3. Khedgikar V, Lehoczky JA. Evidence for Lgr6 as a Novel Marker of Osteoblastic Progenitors in Mice. JBMR Plus. 2019 Feb; 3(2):e10075. PMID: 30828690.
    Citations:    
  4. Karvande A, Khan S, Khan I, Singh D, Khedgikar V, Kushwaha P, Ahmad N, Kothari P, Dhasmana A, Kant R, Trivedi R, Chauhan PMS. Discovery of a tetrazolyl ß-carboline with in vitro and in vivo osteoprotective activity under estrogen-deficient conditions. Medchemcomm. 2018 Jul 01; 9(7):1213-1225. PMID: 30109010.
    Citations:    
  5. Mathavan K, Khedgikar V, Bartolo V, Alfandari D. The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration. PLoS One. 2017; 12(11):e0188963. PMID: 29190819.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Khedgikar V, Abbruzzese G, Mathavan K, Szydlo H, Cousin H, Alfandari D. Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2a and arid3a. Elife. 2017 08 22; 6. PMID: 28829038.
    Citations: 3     Fields:    Translation:AnimalsCells
  7. Karvande A, Khedgikar V, Kushwaha P, Ahmad N, Kothari P, Verma A, Kumar P, Nagar GK, Mishra PR, Maurya R, Trivedi R. Heartwood extract from Dalbergia sissoo promotes fracture healing and its application in ovariectomy-induced osteoporotic rats. J Pharm Pharmacol. 2017 Oct; 69(10):1381-1397. PMID: 28664619.
    Citations: 2     Fields:    Translation:Animals
  8. Gautam J, Khedgikar V, Kushwaha P, Choudhary D, Nagar GK, Dev K, Dixit P, Singh D, Maurya R, Trivedi R. Formononetin, an isoflavone, activates AMP-activated protein kinase/ß-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss. Br J Nutr. 2017 Mar; 117(5):645-661. PMID: 28367764.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Kumar P, Kushwaha P, Ahmad N, Maurya SW, Dev K, Khedgikar V, Siddiqui IR, Trivedi R, Maurya R. Design and synthesis of dalbergin analogues and evaluation of anti-osteoporotic activity. Bioorg Med Chem Lett. 2017 04 15; 27(8):1765-1775. PMID: 28274632.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Ahmad N, Chillara R, Kushwaha P, Khedgikar V, Karvande A, Choudhary D, Adhikary S, Maurya R, Trivedi R. Evaluation of anti-osteoporotic activity of butanolic fraction from Passiflora foetida in ovariectomy-induced bone loss in mice. Biomed Pharmacother. 2017 Apr; 88:804-813. PMID: 28160755.
    Citations: 3     Fields:    Translation:AnimalsCells
  11. Khedgikar V, Kushwaha P, Ahmad N, Gautam J, Kumar P, Maurya R, Trivedi R. Ethanolic extract of Dalbergia sissoo promotes rapid regeneration of cortical bone in drill-hole defect model of rat. Biomed Pharmacother. 2017 Feb; 86:16-22. PMID: 27936389.
    Citations:    Fields:    Translation:AnimalsCells
  12. Kushwaha P, Khedgikar V, Ahmad N, Karvande A, Gautam J, Kumar P, Maurya R, Trivedi R. A neoflavonoid dalsissooal isolated from heartwood of Dalbergia sissoo Roxb. has bone forming effects in mice model for osteoporosis. Eur J Pharmacol. 2016 Oct 05; 788:65-74. PMID: 27316792.
    Citations: 4     Fields:    Translation:AnimalsCells
  13. Gautam J, Khedgikar V, Choudhary D, Kushwaha P, Dixit P, Singh D, Maurya R, Trivedi R. An isoflavone cladrin prevents high-fat diet-induced bone loss and inhibits the expression of adipogenic gene regulators in 3T3-L1 adipocyte. J Pharm Pharmacol. 2016 Aug; 68(8):1051-63. PMID: 27265669.
    Citations:    Fields:    Translation:AnimalsCells
  14. Kushwaha P, Khedgikar V, Haldar S, Gautam J, Mulani FA, Thulasiram HV, Trivedi R. Azadirachta indica triterpenoids promote osteoblast differentiation and mineralization in vitro and in vivo. Bioorg Med Chem Lett. 2016 08 01; 26(15):3719-24. PMID: 27317644.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  15. Khedgikar V, Kushwaha P, Gautam J, Sharma S, Verma A, Choudhary D, Mishra PR, Trivedi R. Kaempferol targets Krt-14 and induces cytoskeletal mineralization in osteoblasts: A mechanistic approach. Life Sci. 2016 Apr 15; 151:207-217. PMID: 26956522.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Kushwaha P, Khedgikar V, Sharma D, Yuen T, Gautam J, Ahmad N, Karvande A, Mishra PR, Trivedi PK, Sun L, Bhadada SK, Zaidi M, Trivedi R. MicroRNA 874-3p Exerts Skeletal Anabolic Effects Epigenetically during Weaning by Suppressing Hdac1 Expression. J Biol Chem. 2016 Feb 19; 291(8):3959-66. PMID: 26663087.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Gautam J, Kumar P, Kushwaha P, Khedgikar V, Choudhary D, Singh D, Maurya R, Trivedi R. Neoflavonoid dalbergiphenol from heartwood of Dalbergia sissoo acts as bone savior in an estrogen withdrawal model for osteoporosis. Menopause. 2015 Nov; 22(11):1246-55. PMID: 25850356.
    Citations:    Fields:    Translation:HumansAnimals
  18. Shukla P, Mathur V, Kumar A, Khedgikar V, Teja VB, Chaudhary D, Kushwaha P, Bora HK, Konwar R, Trivedi R, Mishra PR. Nanoemulsion based concomitant delivery of curcumin and etoposide: impact on cross talk between prostate cancer cells and osteoblast during metastasis. J Biomed Nanotechnol. 2014 Nov; 10(11):3381-91. PMID: 26000396.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  19. Kushwaha P, Khedgikar V, Gautam J, Dixit P, Chillara R, Verma A, Thakur R, Mishra DP, Singh D, Maurya R, Chattopadhyay N, Mishra PR, Trivedi R. A novel therapeutic approach with Caviunin-based isoflavonoid that en routes bone marrow cells to bone formation via BMP2/Wnt-ß-catenin signaling. Cell Death Dis. 2014 Sep 18; 5:e1422. PMID: 25232676.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  20. Khedgikar V, Ahmad N, Kushwaha P, Gautam J, Nagar GK, Singh D, Trivedi PK, Mishra PR, Sangwan NS, Trivedi R. Preventive effects of withaferin A isolated from the leaves of an Indian medicinal plant Withania somnifera (L.): comparisons with 17-ß-estradiol and alendronate. Nutrition. 2015 Jan; 31(1):205-13. PMID: 25466667.
    Citations: 3     Fields:    Translation:AnimalsCells
  21. Kumar P, Kushwaha P, Khedgikar V, Gautam J, Choudhary D, Singh D, Trivedi R, Maurya R. Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood. Bioorg Med Chem Lett. 2014 Jun 15; 24(12):2664-8. PMID: 24803361.
    Citations: 1     Fields:    Translation:AnimalsCells
  22. Gautam J, Choudhary D, Khedgikar V, Kushwaha P, Singh RS, Singh D, Tiwari S, Trivedi R. Micro-architectural changes in cancellous bone differ in female and male C57BL/6 mice with high-fat diet-induced low bone mineral density. Br J Nutr. 2014 May 28; 111(10):1811-21. PMID: 24506951.
    Citations: 12     Fields:    Translation:AnimalsCells
  23. Sashidhara KV, Modukuri RK, Choudhary D, Bhaskara Rao K, Kumar M, Khedgikar V, Trivedi R. Synthesis and evaluation of new coumarin-pyridine hybrids with promising anti-osteoporotic activities. Eur J Med Chem. 2013; 70:802-10. PMID: 24246729.
    Citations: 1     Fields:    Translation:AnimalsCells
  24. Khedgikar V, Kushwaha P, Gautam J, Verma A, Changkija B, Kumar A, Sharma S, Nagar GK, Singh D, Trivedi PK, Sangwan NS, Mishra PR, Trivedi R. Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone. Cell Death Dis. 2013 Aug 22; 4:e778. PMID: 23969857.
    Citations: 24     Fields:    Translation:AnimalsCells
  25. Gupta GK, Kumar A, Khedgikar V, Kushwaha P, Gautam J, Nagar GK, Gupta V, Verma A, Dwivedi AK, Misra A, Trivedi R, Mishra PR. Osteogenic efficacy enhancement of kaempferol through an engineered layer-by-layer matrix: a study in ovariectomized rats. Nanomedicine (Lond). 2013 May; 8(5):757-71. PMID: 23311987.
    Citations: 1     Fields:    Translation:Animals
  26. Sashidhara KV, Kumar M, Khedgikar V, Kushwaha P, Modukuri RK, Kumar A, Gautam J, Singh D, Sridhar B, Trivedi R. Discovery of coumarin-dihydropyridine hybrids as bone anabolic agents. J Med Chem. 2013 Jan 10; 56(1):109-22. PMID: 23214410.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  27. Khedgikar V, Gautam J, Kushwaha P, Kumar A, Nagar GK, Dixit P, Chillara R, Voruganti S, Singh SP, Uddin W, Jain GK, Singh D, Maurya R, Chattopadhyay N, Trivedi R. A standardized phytopreparation from an Indian medicinal plant (Dalbergia sissoo) has antiresorptive and bone-forming effects on a postmenopausal osteoporosis model of rat. Menopause. 2012 Dec; 19(12):1336-46. PMID: 22850441.
    Citations: 3     Fields:    Translation:HumansAnimals
  28. Gautam J, Kushwaha P, Swarnkar G, Khedgikar V, Nagar GK, Singh D, Singh V, Jain M, Barthwal M, Trivedi R. EGb 761 promotes osteoblastogenesis, lowers bone marrow adipogenesis and atherosclerotic plaque formation. Phytomedicine. 2012 Sep 15; 19(12):1134-42. PMID: 22951391.
    Citations: 5     Fields:    Translation:AnimalsCells
  29. Kumar A, Gupta GK, Khedgikar V, Gautam J, Kushwaha P, Changkija B, Nagar GK, Gupta V, Verma A, Dwivedi AK, Chattopadhyay N, Mishra PR, Trivedi R. In vivo efficacy studies of layer-by-layer nano-matrix bearing kaempferol for the conditions of osteoporosis: a study in ovariectomized rat model. Eur J Pharm Biopharm. 2012 Nov; 82(3):508-17. PMID: 22926146.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Dixit P, Chillara R, Khedgikar V, Gautam J, Kushwaha P, Kumar A, Singh D, Trivedi R, Maurya R. Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity. Bioorg Med Chem Lett. 2012 Jan 15; 22(2):890-7. PMID: 22212722.
    Citations: 3     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.