Harvard Catalyst Profiles

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Laura Alice Stransky, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F31CA189321 (STRANSKY, LAURA ALICE) Apr 1, 2015 - Sep 30, 2017
    Elucidating the mechanism of mTORC1 activation by amino acids
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Grubb T, Maganti S, Krill-Burger JM, Fraser C, Stransky L, Radivoyevitch T, Sarosiek KA, Vazquez F, Kaelin WG, Chakraborty AA. A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Antiapoptotic Protein in Kidney Cancer. Clin Cancer Res. 2022 Nov 01; 28(21):4689-4701. PMID: 35776130; PMCID: PMC9633392.
    Citations:    Fields:    
  2. Stransky LA, Vigeant SM, Huang B, West D, Denize T, Walton E, Signoretti S, Kaelin WG. Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not require an intact p53 pathway. Proc Natl Acad Sci U S A. 2022 04 05; 119(14):e2120403119. PMID: 35357972; PMCID: PMC9168943.
    Citations: 1     Fields:    Translation:HumansCells
  3. Collins MP, Stransky LA, Forgac M. AKT Ser/Thr kinase increases V-ATPase-dependent lysosomal acidification in response to amino acid starvation in mammalian cells. J Biol Chem. 2020 07 10; 295(28):9433-9444. PMID: 32409581.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  4. Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG. HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species. Sci Signal. 2019 10 01; 12(601). PMID: 31575731.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  5. McGuire C, Stransky L, Cotter K, Forgac M. Regulation of V-ATPase activity. Front Biosci (Landmark Ed). 2017 01 01; 22(4):609-622. PMID: 27814636.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  6. Stransky L, Cotter K, Forgac M. The Function of V-ATPases in Cancer. Physiol Rev. 2016 07; 96(3):1071-91. PMID: 27335445; PMCID: PMC4982037.
    Citations: 98     Fields:    Translation:HumansAnimalsCells
  7. McGuire C, Cotter K, Stransky L, Forgac M. Regulation of V-ATPase assembly and function of V-ATPases in tumor cell invasiveness. Biochim Biophys Acta. 2016 Aug; 1857(8):1213-1218. PMID: 26906430; PMCID: PMC4922897.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  8. Cotter K, Stransky L, McGuire C, Forgac M. Recent Insights into the Structure, Regulation, and Function of the V-ATPases. Trends Biochem Sci. 2015 Oct; 40(10):611-622. PMID: 26410601; PMCID: PMC4589219.
    Citations: 124     Fields:    Translation:HumansAnimalsCells
  9. Stransky LA, Forgac M. Amino Acid Availability Modulates Vacuolar H+-ATPase Assembly. J Biol Chem. 2015 Nov 06; 290(45):27360-27369. PMID: 26378229; PMCID: PMC4646367.
    Citations: 62     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.