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Yann Cormerais, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Byles V, Cormerais Y, Kalafut K, Barrera V, Hughes Hallett JE, Sui SH, Asara JM, Adams CM, Hoxhaj G, Ben-Sahra I, Manning BD. Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin. Mol Metab. 2021 11; 53:101309. PMID: 34303878; PMCID: PMC8368025.
    Citations: 2     Fields:    Translation:AnimalsCells
  2. Meira W, Daher B, Parks SK, Cormerais Y, Durivault J, Tambutte E, Pouyssegur J, Vucetic M. A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCTKO Pancreatic Ductal Adenocarcinoma Cells. Cancers (Basel). 2021 Mar 21; 13(6). PMID: 33801101.
    Citations: 1     
  3. Cormerais Y, Vucetic M, Parks SK, Pouyssegur J. Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer. Int J Mol Sci. 2020 Dec 22; 22(1). PMID: 33375025; PMCID: PMC7792758.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  4. Cormerais Y, Vucetic M, Pouysségur J. Targeting amino acids transporters (SLCs) to starve cancer cells to death. Biochem Biophys Res Commun. 2019 12 17; 520(4):691-693. PMID: 31761081.
    Citations: 3     Fields:    Translation:HumansCells
  5. Daher B, Parks SK, Durivault J, Cormerais Y, Baidarjad H, Tambutte E, Pouysségur J, Vucetic M. Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses. Cancer Res. 2019 08 01; 79(15):3877-3890. PMID: 31175120.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  6. Cormerais Y, Pagnuzzi-Boncompagni M, Schrötter S, Giuliano S, Tambutté E, Endou H, Wempe MF, Pagès G, Pouysségur J, Picco V. Inhibition of the amino-acid transporter LAT1 demonstrates anti-neoplastic activity in medulloblastoma. J Cell Mol Med. 2019 04; 23(4):2711-2718. PMID: 30784173; PMCID: PMC6433660.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  7. Giuliano S, Dufies M, Ndiaye PD, Viotti J, Borchiellini D, Parola J, Vial V, Cormerais Y, Ohanna M, Imbert V, Chamorey E, Rioux-Leclercq N, Savina A, Ferrero JM, Mograbi B, Pagès G. Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5. Theranostics. 2019; 9(4):1181-1199. PMID: 30867824; PMCID: PMC6401402.
    Citations: 9     Fields:    Translation:HumansCells
  8. Cormerais Y, Massard PA, Vucetic M, Giuliano S, Tambutté E, Durivault J, Vial V, Endou H, Wempe MF, Parks SK, Pouyssegur J. The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5). J Biol Chem. 2018 02 23; 293(8):2877-2887. PMID: 29326164.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  9. Persaud A, Cormerais Y, Pouyssegur J, Rotin D. Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin. J Cell Sci. 2018 01 04; 131(1). PMID: 29150487.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  10. Vucetic M, Cormerais Y, Parks SK, Pouysségur J. The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code. Front Oncol. 2017; 7:319. PMID: 29312889; PMCID: PMC5742588.
    Citations: 33     
  11. Courtial L, Picco V, Grover R, Cormerais Y, Rottier C, Labbe A, Pagès G, Ferrier-Pagès C. The c-Jun N-terminal kinase prevents oxidative stress induced by UV and thermal stresses in corals and human cells. Sci Rep. 2017 04 04; 7:45713. PMID: 28374828.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  12. Parks SK, Cormerais Y, Pouysségur J. Hypoxia and cellular metabolism in tumour pathophysiology. J Physiol. 2017 04 15; 595(8):2439-2450. PMID: 28074546; PMCID: PMC5390873.
    Citations: 50     Fields:    Translation:HumansAnimals
  13. Parks SK, Cormerais Y, Durivault J, Pouyssegur J. Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells. Oncotarget. 2017 Feb 07; 8(6):10225-10237. PMID: 28055960.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  14. Cormerais Y, Giuliano S, LeFloch R, Front B, Durivault J, Tambutté E, Massard PA, de la Ballina LR, Endou H, Wempe MF, Palacin M, Parks SK, Pouyssegur J. Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth. Cancer Res. 2016 08 01; 76(15):4481-92. PMID: 27302165.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  15. Parks SK, Cormerais Y, Marchiq I, Pouyssegur J. Hypoxia optimises tumour growth by controlling nutrient import and acidic metabolite export. Mol Aspects Med. 2016 Feb-Mar; 47-48:3-14. PMID: 26724171.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  16. Giuliano S, Cormerais Y, Dufies M, Grépin R, Colosetti P, Belaid A, Parola J, Martin A, Lacas-Gervais S, Mazure NM, Benhida R, Auberger P, Mograbi B, Pagès G. Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux. Autophagy. 2015; 11(10):1891-904. PMID: 26312386.
    Citations: 55     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.